AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Neoplasm, ResidualPancreatic NeoplasmsNeoplasmsNeoplasms, Cystic, Mucinous, and SerousSkin NeoplasmsNeoplasms, Multiple PrimaryKidney NeoplasmsNeoplasms, Second PrimaryThyroid NeoplasmsAdenocarcinoma, MucinousMyeloproliferative DisordersDNA, NeoplasmLung NeoplasmsOvarian NeoplasmsLiver NeoplasmsParotid NeoplasmsFunctional Residual CapacityCystadenomaNeoplasms, Connective and Soft TissueNeoplasms, Plasma CellAppendiceal NeoplasmsResidual VolumeTesticular NeoplasmsImmunohistochemistryCystadenoma, MucinousEndocrine Gland NeoplasmsGastrointestinal NeoplasmsNeoplasms, ExperimentalCarcinoma, Pancreatic DuctalNeoplasm StagingEye NeoplasmsNeoplasms, Vascular TissueNeoplasms, Glandular and EpithelialCarcinoma, PapillaryNose NeoplasmsNeoplasms, Radiation-InducedSalivary Gland NeoplasmsAdenocarcinoma, PapillaryAdenomaNeoplasm ProteinsNeoplasms, Muscle TissueSoft Tissue NeoplasmsHematologic NeoplasmsCystadenocarcinoma, MucinousUterine NeoplasmsLymphomaIntestinal NeoplasmsAntigens, NeoplasmNeoplasms, Adnexal and Skin AppendageTumor Markers, BiologicalBone NeoplasmsVascular NeoplasmsSweat Gland NeoplasmsNeoplasm InvasivenessPalatal NeoplasmsTreatment OutcomeNeoplasms, Germ Cell and EmbryonalRetrospective StudiesNeoplasms, Complex and MixedBile Duct NeoplasmsNeoplasm Recurrence, LocalThymus NeoplasmsBone Marrow NeoplasmsMandibular NeoplasmsCystadenocarcinomaColonic NeoplasmsHeart NeoplasmsSplenic NeoplasmsMeningeal NeoplasmsCystadenoma, SerousDog DiseasesMaxillary NeoplasmsMediastinal NeoplasmsTomography, X-Ray ComputedAnal Gland NeoplasmsColorectal NeoplasmsNeoplasms, Adipose TissueDuodenal NeoplasmsMouth NeoplasmsCarcinomaTime FactorsPrognosisAdenocarcinomaBreast NeoplasmsAdrenal Cortex NeoplasmsFollow-Up StudiesStomach NeoplasmsUrinary Bladder NeoplasmsNeoplasm MetastasisSpinal Cord NeoplasmsTongue NeoplasmsIleal NeoplasmsMuscle NeoplasmsCarcinoma, Acinar CellVaginal NeoplasmsCerebral Ventricle NeoplasmsHemangiosarcomaAdenoma, OxyphilicPancreatectomyLiver Neoplasms, Experimental
Breast NeoplasmsRecurrenceMyeloidMalignant neoplasmsMeasurableBenignLymphoid NeoplasmsMinimal residual diseaseNext-Generation SequencingCenters for DiseasCarcinoma in sDetectionAcute lymphoblaCancerDiagnosisBone marrowTumorPatients with residual diseaseSurvivalLiquid biopsyClinicalObstructivePathologicEvidence of residualGeneticRemissionPediatricsPeripheralLymphomaMultiple MyelomaFlowPostoperativeRadioactive iodinePediatricTrastuzumabMutationTumourTumorsPersistentRelapseRepresentsProgesteronePlasmaMeSH
Breast Neoplasms3
  • This is a systematic review of studies in the PubMed database to April 2013, which fit the eligibility criterion of "Inflammatory Breast Neoplasms" (MeSH Terms), filtered by Languages (English OR Portuguese OR Spanish). (bvsalud.org)
  • inflammatory breast neoplasms, medical oncology. (bvsalud.org)
  • What has been researched about inflammatory breast neoplasms? (bvsalud.org)
Recurrence6
  • The primary end point was invasive disease-free survival (defined as freedom from ipsilateral invasive breast tumor recurrence, ipsilateral locoregional invasive breast cancer recurrence, contralateral invasive breast cancer, distant recurrence, or death from any cause). (nih.gov)
  • Distant recurrence as the first invasive-disease event occurred in 10.5% of patients in the T-DM1 group and 15.9% of those in the trastuzumab group. (nih.gov)
  • Among patients with HER2-positive early breast cancer who had residual invasive disease after completion of neoadjuvant therapy, the risk of recurrence of invasive breast cancer or death was 50% lower with adjuvant T-DM1 than with trastuzumab alone. (nih.gov)
  • No patient developed disease recurrence. (ox.ac.uk)
  • Conversely, there are many arguments in favor of performing ND only for patients who have evidence of residual neck disease because of the very low probability of isolated neck recurrence following a complete response. (nih.gov)
  • it is also used to prognosticate the recurrence of diseases, particularly malignancies. (medscape.com)
Myeloid6
  • The purpose of this research study is to test the safety and efficacy of cytokine induced memory-like (CIML) natural killer (NK) cells expanded with Interleukin-2 (IL-2) at preventing relapse in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or MDS and myeloproliferative neoplasm (MPN) overlap syndrome after a standard-of-care stem cell transplant. (survivornet.com)
  • This is a phase I/Ib study of the pre-emptive treatment using related donor-derived cytokine induced memory-like (CIML) natural killer (NK) cells combined with Interleukin-2 (IL-2) for participants with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and MDS/myeloproliferative neoplasm (MDS/MPN) overlap syndrome at high risk for post-allogeneic stem cell transplant (SCT) relapse. (survivornet.com)
  • He is interested in functionally characterizing the role of sequentially acquired mutations in myeloid neoplasms. (mskcc.org)
  • Sufferers with myeloid neoplasms who relapsed after allogenic hematopoietic stem cell transplant (HSCT) have poor prognosis. (ngsbioinformatics.com)
  • Real-time quantitative polymerase chain reaction (qPCR) has been extensively validated for the detection of minimal residual disease (MRD) in acute myeloid leukaemia (AML). (elsevierpure.com)
  • The publication contains an introduction to immunophenotypic changes seen in normal hematopoiesis along with an overview of the evaluation of lymphomas, leukemias, and myeloid stem-cell neoplasms. (cap.org)
Malignant neoplasms3
  • Such clinical phenotypes can mimic infectious and autoimmune causes of meningoencephalitis.Objective: To ascertain whether CSF metagenomic next-generation sequencing (mNGS) can identify aneuploidy, a hallmark of malignant neoplasms, in difficult-to-diagnose cases of CNS malignant neoplasm.Design, Setting, and Participants: Two case-control studies were performed at the University of California, San Francisco (UCSF). (stanford.edu)
  • In state that the specific listing evaluates certain and specific malignant neoplasms, but not certain neoplasms associated with HIV infection. (disabilitybenefitscenter.org)
  • 1986. A retrospective study on malignant neoplasms of bladder, lung, and liver in Blackfoot disease endemic area in Taiwan. (cdc.gov)
Measurable6
  • It has been postulated that monitoring measurable residual disease (MRD) could be used as a surrogate marker of progression-free survival (PFS) in chronic lymphocytic leukemia (CLL) patients after treatment with immunochemotherapy regimens. (haematologica.org)
  • Administering time-limitedcombination regimens of venetoclax plus obinutuzumab or venetoclax plus obinutuzumab and ibrutinib was superior to chemoimmunotherapy in achieving undetectable measurable residual disease (MRD) in the peripheral blood at month 15 in fit patients with chronic lymphocytic. (ascopost.com)
  • Exposition found that fixed-duration treatment with ibrutinib and venetoclax achieved deep and sustained undetectable measurable residual disease (MRD) status when used as first-line therapy for. (ascopost.com)
  • Histologically or cytologically confirmed diagnosis of AML, MDS, or MDS/MPN that is at high risk for post-transplant relapse and that has measurable disease prior to transplant using MRD-depth next-generation duplex sequencing with error suppression. (survivornet.com)
  • Results with docetaxel as a single agent and in combination regimens with estramustine (Emcyt) have consistently achieved a palliative response, reduced serum PSA levels by 50% or more, and produced objective responses in patients with measurable disease. (cancernetwork.com)
  • Flow cytometric features in AML, MDS, CMML, CLL and measurable residual disease were significantly expanded. (ebooksmedicine.net)
Benign4
  • In benign prostatic hyperplasia normal values for NEC and TC were determined in stages without residual urine. (uni-muenchen.de)
  • FTC resembles the normal microscopic pattern of the thyroid, and a clear distinction between benign and malignant disease based solely on cytological examination of a needle biopsy specimen may be difficult. (medscape.com)
  • Neoplasms, benign, any specified part of respiratory system. (kdvma.com)
  • A definitive clinicopathologic correlation was obtained in 66.8% (1224/1831) and this was 64.8% for benign tumours, 60.4% for malignant tumours, 66.7% for inflammatory diseases, 70.8% for infections, 85.5% for scalp and hair disorders and 50% for dermal deposits. (bvsalud.org)
Lymphoid Neoplasms1
  • A new integrative, capture-based, next-generation sequencing (NGS) panel, LYmphoid NeXt-Generation Sequencing (LYNX), can detect and analyze standard and novel biomarkers in the most common lymphoid neoplasms simultaneously. (ceitec.eu)
Minimal residual disease1
  • Campana D. Should minimal residual disease monitoring in acute lymphoblastic leukemia be standard of care? (smw.ch)
Next-Generation Sequencing1
Centers for Diseas1
  • I'm Captain Ibad Khan and I'm I am representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch of the Centers for Disease Control and Prevention. (cdc.gov)
Carcinoma in s1
  • The aim of this report is to update pathologists, clinicians and researchers on TIL assessment in both the post-neoadjuvant residual disease and the ductal carcinoma in situ settings. (edu.pe)
Detection1
  • Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia. (smw.ch)
Acute lymphobla1
  • Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry. (smw.ch)
Cancer5
  • Patients who have residual invasive breast cancer after receiving neoadjuvant chemotherapy plus human epidermal growth factor receptor 2 (HER2)-targeted therapy have a worse prognosis than those who have no residual cancer. (nih.gov)
  • We conducted a phase 3, open-label trial involving patients with HER2-positive early breast cancer who were found to have residual invasive disease in the breast or axilla at surgery after receiving neoadjuvant therapy containing a taxane (with or without anthracycline) and trastuzumab. (nih.gov)
  • Current National Comprehensive Cancer Network (NCCN) guidelines recommend lobectomy plus isthmusectomy as the initial surgery for patients with follicular neoplasms, with prompt completion of thyroidectomy if invasive FTC is found on the final histologic section. (medscape.com)
  • The NCCN recommends total thyroidectomy as the initial procedure only if invasive cancer or metastatic disease is apparent at the time of surgery, or if the patient wishes to avoid a second, completion thyroidectomy should the pathologic review reveal cancer. (medscape.com)
  • Although testicular cancer is a rare disease accounting for only 1% of all male neoplasms, it represents a paradigm for cancer curability. (cancernetwork.com)
Diagnosis6
  • It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
  • Using multi-color techniques pioneered by Brent Wood, the text demonstrates a unique approach to diagnosis of hematopoietic malignancies as well as identification of small abnormal populations in the posttherapy setting (minimal residual disease testing). (cap.org)
  • Each case provides detailed, full-color images of flow cytometric dot plots that clearly outline the features of the disease, accompanied by a clinical history and thorough discussion, enabling readers to develop and work through a differential diagnosis and recognize potential diagnostic pitfalls. (cap.org)
  • Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM0902) study. (cdc.gov)
  • The diagnosis of many infectious diseases, both viral and bacterial, may include the use of reverse transcriptase-polymerase chain reaction (RT-PCR). (medscape.com)
  • Flow cytometry is an important methodology for the diagnosis of chronic B-cell lymphoproliferative diseases (B-CLPD), however, sometimes the cytometrist does not find sufficient elements for the exact definition of the pathological entity involved. (bvsalud.org)
Bone marrow3
  • Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia. (smw.ch)
  • Bone marrow (BM) MRD analysis was performed after the last planned induction course and every 6 months in cases with detectable residual disease during the 36 months of maintenance therapy. (haematologica.org)
  • Detecting minimal residual disease in bone marrow samples during treatment or after therapy has become increasingly important. (mayocliniclabs.com)
Tumor8
  • Solid pseudopapillary tumor of the pancreas is considered a rare neoplasm, which predominately affects young African American women [ 1 ]. (hindawi.com)
  • The origins of the tumor remain unknown, and there are no identifiable risk factors which have been associated with the development of the neoplasm. (hindawi.com)
  • Even after successful resection of the tumor, attention needs to be paid to patients who subsequently become pregnant, secondary to any residual disease having a heightened sensitivity to increased levels of progesterone. (hindawi.com)
  • Solid pseudopapillary tumor of the pancreas is a rare neoplasm of the pancreas, predominately affecting the exocrine function of the pancreas. (hindawi.com)
  • Hysterectomy specimens revealed 64.1% (50/78) of the patients had pathologic residual tumor. (koreamed.org)
  • Patients age less than 60, tumor size over 4 cm, stage IIB and persistent residual disease after CCRT were most likely to benefit from hysterectomy. (koreamed.org)
  • In a series of case presentations, we review the evaluation and management of patients with persistent elevation of serum tumor markers and postchemotherapy residual radiographic abnormalities. (cancernetwork.com)
  • We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)
Patients with residual disease1
  • As planned surgery will only benefit patients with residual disease in the neck alone, there is a high rate of unnecessary ND with its associated morbidity. (nih.gov)
Survival3
  • After a median followup of 6.30 years, the median overall survival (OS) and PFS had not been reached in patients with either undetectable or detectable residual disease in the BM, who had achieved a complete response at the time of starting maintenance therapy. (haematologica.org)
  • Patients who do not achieve a minimal residual disease (MRD) negative status will relapse faster and have a shorter survival length. (mayocliniclabs.com)
  • Proponents of a systematic planned ND argue that it improves regional control and possibly disease-specific survival. (nih.gov)
Liquid biopsy1
  • So, the negative predictive value is another important feature when we talk about liquid biopsy and in terms of disease monitoring. (medscape.com)
Clinical6
  • The first study used CSF specimens collected at the UCSF Clinical Laboratories between July 1, 2017, and December 31, 2019, and evaluated test performance in specimens from patients with a CNS malignant neoplasm (positive controls) or without (negative controls). (stanford.edu)
  • TILs in the post-neoadjuvant residual disease setting are acquiring increasing importance as a stratifying marker in clinical trials, considering the raising interest on immunotherapeutic strategies after neoadjuvant chemotherapy. (edu.pe)
  • Flow Cytometry in Evaluation of Hematopoietic Neoplasms provides pathologists, residents, laboratory technologists, and hematologists with both a study guide and an atlas for regular consultation in the clinical flow cytometry laboratory. (cap.org)
  • FTC and other thyroid neoplasms arising from follicular cells (adenomas, papillary/follicular carcinoma, and noninvasive follicular thyroid neoplasm with papillary-like nuclear features [NIFTP]) show a broad range of overlapping clinical and cytologic features. (medscape.com)
  • Special emphasis has been put on hematological neoplasms with crucial clinical significance such as acute promyelocytic leukemia, other acute leukemias, and difficult areas in flow cytometry. (ebooksmedicine.net)
  • The current debate is focused on N2-N3 disease and the ability of a clinical complete response to predict the absence of viable cells in the ND specimen. (nih.gov)
Obstructive1
  • Depending on the specific findings, rate residuals as interstitial lung disease, restrictive lung disease, or, when obstructive lung disease is the major residual, as chronic bronchitis (DC 6600 ). (kdvma.com)
Pathologic1
  • This edition incorporates the updated WHO classification of hematopoietic tumors and new immunophenotypic and molecular markers to provide a thorough pathologic overview of hematologic neoplasms while focusing on flow cytometric features. (ebooksmedicine.net)
Evidence of residual2
  • She was followed up in surgery clinic and underwent a CT of the abdomen and pelvis one year later which did not demonstrate any evidence of residual or metastatic disease. (hindawi.com)
  • There was no evidence of residual disease at the time of surgery. (hindawi.com)
Genetic1
  • Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status. (lu.se)
Remission1
  • Minimal residual disease (MRD) refers to the small number of malignant cells that remain after therapy when the patient is in remission and shows no symptoms or overt signs of disease. (smw.ch)
Pediatrics1
  • Dr. Bryant is a member of AAP's Committee on Infectious Diseases and she's a Professor of Pediatrics at the University of Louisville School of Medicine. (cdc.gov)
Peripheral3
  • Myeloproliferative diseases are a heterogeneous group of disorders characterized by cellular proliferation of one or more hematologic cell lines in the peripheral blood, distinct from acute leukemia. (medscape.com)
  • As per protocol, 15 patients (17.8%), who achieved a complete response and undetectable peripheral blood and BM residual disease after four courses of induction, were allowed to stop fludarabine and cyclophosphamide and complete two additional courses of rituximab and continue with maintenance therapy for 18 cycles. (haematologica.org)
  • is a practical, case-based guide to flow cytometric analysis in the workup of hematopoietic neoplasms presenting in the peripheral blood, marrow, lymphoid tissue, and extranodal sites. (cap.org)
Lymphoma1
  • Joshua Brody, MD, Director of the CLL/Lymphoma Immunotherapy Program, Icahn School of Medicine at Mount Sinai, New York, who was not involved in these trials, commented: "CLL is an extremely prevalent disease affecting nearly 200,000 patients in the United States. (ascopost.com)
Multiple Myeloma1
  • MASS-FIX is now included in International Myeloma Working Group recommendations as an accepted method for monitoring of M-protein-based diseases such as MGUS and multiple myeloma. (mayocliniclabs.com)
Flow2
  • Importance: Cerebrospinal fluid (CSF) cytologic testing and flow cytometry are insensitive for diagnosing neoplasms of the central nervous system (CNS). (stanford.edu)
  • The results emphasize that even though flow cytometry is important for the characterization of B-CLPD, sometimes the cytometrist needs to include the category "other chronic B-cell lymphoproliferative diseases not classified by flow cytometry" in the report to induce the prescriber to request additional complementary exams. (bvsalud.org)
Postoperative1
  • 4 cm or that are diffusely spreading require total or near-total thyroidectomy with postoperative radioiodine ablation of residual thyroid tissue with appropriately large doses of iodine-131 administered when the patient is hypothyroid or after recombinant thyroid-stimulating hormone (TSH) injections. (msdmanuals.com)
Radioactive iodine3
  • If all gross disease cannot be resected, or if residual disease is not avid for radioactive iodine, radiation therapy is often employed for locally advanced disease. (medscape.com)
  • Treatment is surgical removal, usually followed by ablation of residual tissue with radioactive iodine. (msdmanuals.com)
  • 1.5 cm, often followed by ablation of residual tissue with radioactive iodine. (msdmanuals.com)
Pediatric1
  • Pediatric Epidemiology and Infectious Diseases at Norton Children's Medical Group in Louisville, Kentucky. (cdc.gov)
Trastuzumab1
  • The estimated percentage of patients who were free of invasive disease at 3 years was 88.3% in the T-DM1 group and 77.0% in the trastuzumab group. (nih.gov)
Mutation1
  • By isolating and generating iPSC lines from cells of the major clone, cells of the minor clone and residual un-mutated cells all from within the same patient, this will allow for extensive experimentation into the biology and downstream consequences of sequential mutation acquisition in MDS. (mskcc.org)
Tumour1
  • The operation performed, the tumour stage and grade, the extent of residual disease, and the follow-up outcomes were evaluated. (ox.ac.uk)
Tumors1
  • NGS studies have identified several genomic alterations in hematologic malignant tumors, which have improved our understanding of the disease course as well as the evolution of these neoplasms. (ceitec.eu)
Persistent1
  • TSH-suppressive doses of levothyroxine are given after treatment, and serum thyroglobulin levels are measured to help detect recurrent or persistent disease. (msdmanuals.com)
Relapse1
  • Prospective minimal residual disease monitoring to predict relapse of acute promyelocytic leukemia and to direct pre-emptive arsenic trioxide therapy. (smw.ch)
Represents2
  • It usually represents a disease or a pathogen, but it can also be an isolated symptom or (developmental) anomaly of the body. (wikipedia.org)
  • This represents a crucial step towards more effective personalized treatment of these diseases and facilitates further research, report researchers in The Journal of Molecular Diagnostics . (ceitec.eu)
Progesterone1
  • however, increased attention was paid to the patient during her pregnancy secondary to elevated hormonal levels of progesterone, which any residual disease would have a heightened sensitivity to. (hindawi.com)
Plasma1
  • High-dose B vitamin supplementation acid, vitamins B6, B12, D and calcium improves folate and folate levels uncovered making use of deeply and cognitive decline in Alzheimer disease: status and decreases plasma homocysteine sequenced large datasets [url=https://modestedu.com/technology/order-online-pirfenex-no-rx/] medications neuropathy purchase generic pirfenex online[/url]. (ehd.org)
MeSH1
  • 29 disease terms (MeSH) has been reported with BIRC3 gene. (cdc.gov)