• The cause of Jessner lymphocytic infiltration of the skin (LIS) is unknown. (medscape.com)
  • One study has linked Borrelia infection with lymphocytic infiltration of the skin. (medscape.com)
  • Both UVA and/or UVB elicit abnormal papular phototest reactions resembling lesions of lymphocytic infiltration of the skin both clinically and histologically in some patients. (medscape.com)
  • Some data suggest that a photosensitivity history in patients with Jessner lymphocytic infiltration of the skin should be sought and confirmed using provocative phototesting. (medscape.com)
  • This relevant event could guide the therapeutic strategy because antimalarials have been effective for Jessner lymphocytic infiltration of the skin patients with photosensitivity. (medscape.com)
  • Prevention is not possible because the etiology of lymphocytic infiltration of the skin is unknown. (medscape.com)
  • Sun avoidance and photoprotection are strongly recommended in all cases with or without a history of photo-aggravation because lymphocytic infiltration of the skin is very likely a photosensitive disorder. (medscape.com)
  • The [ 18 F]FB-IL2 binding potential is a suitable measure for accurate quantification of lymphocytic infiltration in pathological conditions with PET. (springer.com)
  • We do not understand the inducers of the disease and it appears that there are some factors which induce the onset of lymphocytic infiltration. (vin.com)
  • The clinical picture ranges from focal bone lesions to systemic disease with life threatening visceral involvement. (bmj.com)
  • Suprasellar region extension, due to the infiltration of ECD lesions, can cause neurologic manifestations by mass effects, such as headache, visual disturbance, and cranial nerve palsies. (iasp-pain.org)
  • Although SSc-associated ILD (SSc-ILD) is associated more frequently with a nonspecific interstitial pneumonia pattern, which is characterised by homogeneous lesions with predominant inflammatory infiltrates, some aspects of IPF and SSc-ILD suggest that these diseases could share some common features [ 7 ]. (ersjournals.com)
  • Immune infiltration and tumor microenvironment evaluations were assessed by ImmuneScore, ImmuCellAI, and TIMER databases. (frontiersin.org)
  • Increased levels of POGLUT2 could result in the dysregulated immune cell infiltration and tumor microenvironment and showed a significant regulatory effect on the progression of breast cancer through Notch-related signaling. (frontiersin.org)
  • Furthermore, the risk score was significantly related to tumor immune infiltration profiles and genome changes. (biomedcentral.com)
  • It works by increasing immune cell infiltration to the tumor. (survivingmesothelioma.com)
  • Inflammation increased both MCP-1 and TNF-α expression and macrophage infiltration in radial arteries. (medsci.org)
  • Increased levels of ALP are also associated with Von Recklinghausen's disease with bone involvement and malignant infiltrations of bone. (cdc.gov)
  • Studies in animals infected experimentally with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19, provide opportunities to study aspects of the disease that are not easily investigated in human patients. (nature.com)
  • The infiltration of PBMC in the inflammatory lesion is the histopathological hallmark of chronic inflammation, in contrast to the granulocyte infiltration found in acute inflammatory conditions. (springer.com)
  • In some conditions there is a long time of our infectious diseases clinic with acute between the initial and final diagnosis of presentation of pneumonia failed to respond chronic pneumonia, which usually occurs to treatment. (who.int)
  • 3. Acute or chronic infectious diseases (including flu, ARVI) within 30 days before the start of the trial. (who.int)
  • The most frequent abnormality was glycosaminoglycan infiltration and fibrocartilaginous transformation. (bmj.com)
  • Cystic abnormality (honeycombing) occurs in all patients and increases with advanced disease. (msdmanuals.com)
  • Jessner lymphocytic infiltrate of the skin (LIS) is a benign yet chronic, T-cell infiltrative disease, first described in 1953 by Jessner and Kanof. (medscape.com)
  • He was a cigarette smoker with a history of arterial hypertension and chronic obstructive airway disease. (ispub.com)
  • A minority of persons with long-standing T cruzi infection develop the serious cardiac and gastrointestinal problems that characterize chronic symptomatic Chagas disease. (medscape.com)
  • Stereotactic biopsy revealed infiltration by lymphocytes compatible with the diagnosis of chronic lymphocytic leukaemia (CLL). (karger.com)
  • Majumdar G: Chronic lymphocytic leukemia with cerebral infiltration. (karger.com)
  • So encapsulating the cells described in this protocol will give us more of a chronic release of amyloid to use in both in vitro and in vivo systems, and the idea would be this would give us a better understanding of the mechanisms of disease and also allow us to test new treatments. (jove.com)
  • Because IL-2R expression is low in resting immune cells, the receptor might be a suitable biomarker to study active inflammation in chronic inflammatory diseases. (springer.com)
  • An increase in serum phosphatase activity is associated with primary hyperparathyroidism, secondary hyperparathyroidism owing to chronic renal disease, rickets, and osteitis deformans juvenilia due to vitamin D deficiency and malabsorption or renal tubular dystrophies. (cdc.gov)
  • These post-COVID-19 and among patients with fever and chronic kidney or symptoms delay complete recovery and a return to full liver disease, increased creatinine levels, or bilateral functionality ( 3 , 4 ). (who.int)
  • Both SARS-CoV-2 and SARS-CoV use hACE2 but show differences in disease manifestations in patients. (nature.com)
  • It is more frequent in adults, and early diagnosis is crucial since it has been reported to be associated with serious underlying systemic disorders, such as myeloproliferative diseases and severe manifestations like anaphylaxis (2,3). (nih.gov)
  • Neuroendocrine manifestations of Erdheim-Chester disease. (iasp-pain.org)
  • Neuroendocrine manifestations are common in Erdheim-Chester disease (ECD) patients. (iasp-pain.org)
  • Interstitial lung disease (ILD) encompasses a large and diverse group of pathological conditions that share similar clinical, radiological and pathological manifestations, despite potentially having quite different aetiologies and comorbidities. (ersjournals.com)
  • Treatment of MPCM depends on the presence of systemic involvement and/or the clinical symptoms of the disease itself. (nih.gov)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • According to data from the country's Centers for Disease Control and Prevention, synthetic opioids claimed 194 lives a day in 2021. (newslite.tv)
  • The disorder can be confused clinically with rectal cancer or other conditions such as inflammatory bowel disease, even when a biopsy is done. (wikipedia.org)
  • In this project, the DPhil student will assess whether type I and type II perivascular architecture is specific to the synovium, or a universal feature of blood and lymphatic vessels across human pathology, including inflammatory bowel disease, fibrotic diseases, and tumours. (ox.ac.uk)
  • Originally, hormonal stimulation (particularly with progesterone) was suggested in the etiology of PASH, on the basis of observations that this disease is most frequently seen in premenopausal women or in elderly women taking hormone-replacement therapy, and because similar histologic findings are seen in normal mammary stroma during the luteal phase of the menstrual cycle. (health.am)
  • Overview of Idiopathic Interstitial Pneumonias Idiopathic interstitial pneumonias (IIPs) are interstitial lung diseases of unknown etiology that share similar clinical and radiologic features and are distinguished primarily by the histopathologic. (msdmanuals.com)
  • In 1994, after three years of progressive neurological dysfunction, diagnosis of Erdheim-Chester disease was made by analysis of biopsies of the femur bones, showing infiltration with foamy histiocytes lacking Birbeck granules and S-100 protein, and with few lymphocytes. (bmj.com)
  • At the start of the disease there is a small focal infiltration of lymphocytes beneath the capsule of the thyroid. (vin.com)
  • A focal infiltration by lymphocytes occurs. (vin.com)
  • They are all here - some as well-known drugs ~ Cyclosporin, Penicillin ~ some as the scourge of lung diseases ~ Aspergillus ~ some you love to eat and drink ~ Camembert, Roquefort, Beer, Alcoholus, Lager, Quorn, Agaricus campestris, Cantharellus, Bovista ~ and some to blow your mind ~ LSD and Psilocybe. (homeopathic.com)
  • The interstitial lung diseases (ILDs) are a group of diffuse parenchymal lung disorders that are classified according to specific clinical, radiological and histopathological features. (ersjournals.com)
  • Moreover, POGLUT2 on survival and disease progression in pan-cancer was performed using TCGA data. (frontiersin.org)
  • The goal of our research is to develop a novel eye-movement technique to aid the diagnosis and progression monitoring of Huntington's disease (HD). (hdsa.org)
  • This paper focuses on reviewing the existing data on the use of TE in the diagnosis of fibrosis and in monitoring disease progression in alcoholic liver disease, on the factors that may influence the result of fibrosis prediction, and last but not least, on its potential use in assessing the steatosis degree. (wjgnet.com)
  • We have studied the histological progression of the disease. (vin.com)
  • And it may have an impact on disease progression. (survivingmesothelioma.com)
  • Elucidation of the time course of disease onset, the mechanisms of disease progression, and the identity of etiologic agents is essential for effective prevention and treatment. (cdc.gov)
  • Unidimensional transient elastography (TE) is a noninvasive technique, which has been increasingly used in the assessment of diffuse liver diseases. (wjgnet.com)
  • Since these symptoms happen even in the early stages of the disease, can these symptoms be explained by an inability of the striatum to properly signal rewards? (hdsa.org)
  • In fact, we know that in people with other diseases that involve the striatum such as Parkinson's disease, these symptoms are related to abnormal reward signals in the striatum. (hdsa.org)
  • 3 4 We report on two patients with Erdheim-Chester disease with slowly progressive cerebellar dysfunction, associated with pyramidal symptoms. (bmj.com)
  • Serum elevations of ALT activity are rarely observed except in parenchymal liver disease, since ALT is a more liver-specific enzyme than aspartate aminotransferase (AST). (cdc.gov)
  • Idiopathic pulmonary fibrosis (IPF) represents probably the most aggressive form of ILD and systemic sclerosis is a multiorgan fibrotic disease frequently associated with ILD. (ersjournals.com)
  • In SSc, pulmonary disease can exist as a heterogeneous combination of pulmonary fibrosis and pulmonary arterial hypertension (PAH), but the pathogenic mechanisms that induce different pulmonary responses are poorly understood. (ersjournals.com)
  • This schematic view of the morpho-functional unit of the lung (alveolus) depicts the main differences in cellular composition in idiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung disease (SSc-ILD) compared with normal physiological cellular components. (ersjournals.com)
  • Pulmonary fibrosis is a well-known pulmonary infiltration ( 11 ). (who.int)
  • Atherosclerosis, which is believed to be the common pathophysiological basis of cardiovascular disease, is caused by inflammation, oxidative stress, and impaired lipid metabolism [ 2 , 3 ] . (medsci.org)
  • Rheumatoid arthritis (RA) is an autoimmune disease of poorly understood aetiology, primarily characterised by inflammation and swelling of the joints, and which can lead to loss of function and disability (1). (ox.ac.uk)
  • Scattered interstitial inflammation occurs with lymphocyte, plasma cell, and histiocyte infiltration. (msdmanuals.com)
  • Comparative toxicogenomics database analysis revealed associations between core genes (CD14 and CSF1R) and diseases such as OA, osteoporosis, gastritis, juvenile arthritis, diarrhea, and inflammation. (bvsalud.org)
  • 1Department of Infectious Diseases, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran (Correspondence to M. Avijgan: [email protected]). (who.int)
  • Our results therefore demonstrate that activation of the coagulation system at the bacterial surface contributes to the pathophysiology of bacterial infectious diseases. (lu.se)
  • They all share histologically a significant infiltration of affected tissues by langerhans cells. (scirp.org)
  • While much study has been devoted to genetic "triggers" of CNS neurodegeneration-notably mutant Htt in Huntington's disease (HD)-such inherited triggers are typically expressed from early fetal development and are fundamentally inaccessible to timely clinical intervention. (hdsa.org)
  • Notably, although pre-treatment with convalescent plasma prevented most signs of clinical disease, it did not prevent anosmia. (nature.com)
  • Cellular infiltration and exudation characterize conjunctivitis on a cellular level. (medscape.com)
  • Matrix architecture in the perivascular niche: a master regulator of lymphocyte infiltration in inflammatory disease? (ox.ac.uk)
  • This perivascular organization is conserved in different synovial diseases, and matrix composition in this niche significantly correlates with tissue lymphocyte levels in arthritis patient synovial biopsy sections. (ox.ac.uk)
  • Erdheim-Chester disease is a rare, non-Langerhans form of systemic histiocytosis of unknown aetiology. (bmj.com)
  • ECD is a rare non-Langerhans form of histiocytosis with multisystemic infiltration. (iasp-pain.org)
  • Langerhans cell histiocytosis is a rare disease involving clonal proliferation of langerhans cells seen in children and young adults. (scirp.org)
  • Here, using K18-hACE2 transgenic mice that were originally developed for SARS studies 4 , we show that infection with SARS-CoV-2 causes severe disease in the lung and, in some mice, the brain. (nature.com)
  • Here we demonstrate the use of K18-hACE2 mice for studies of COVID-19 disease and treatments. (nature.com)
  • We investigated the expression of immune checkpoints (ICs) on lymphoid populations within the CRC TME and compared with cells from normal colon tissues using samples from 50 patients with varying disease stages. (mdpi.com)
  • Kurowska-Stolarska M, Alivernini S. Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission. (ox.ac.uk)
  • 1 It is associated with tissue infiltration by foamy histiocytes. (bmj.com)
  • Frequently, however, ILDs can also be associated with a specific environmental exposure or an underlying connective tissue disease. (ersjournals.com)
  • The disease probably represents an immune reaction to the abnormal accumulation of altered extracellular matrix in the breast, which is a manifestation of the effects of hyperglycemia on connective tissue. (health.am)
  • Osteoarthritis (OA) is a non-inflammatory degenerative joint disease that mainly involves articular cartilage damage and involves the whole joint tissue. (bvsalud.org)
  • Abdominal echography and CT showed "fat kidneys" with perirenal infiltration. (bmj.com)
  • Albumin measurements are used in the diagnosis and treatment of numerous diseases primarily involving the liver or kidneys. (cdc.gov)
  • CD14 and CSF1R are highly expressed in OA and gastritis, making them potential therapeutic targets for both diseases. (bvsalud.org)
  • In many countries, cancer ranks the second most common cause of death following cardiovascular diseases. (health.am)
  • One year after diagnosis, the patient is in stable disease. (karger.com)
  • This battery of measurements are used in the diagnosis and treatment of certain liver, heart, and kidney diseases, acid-base imbalance in the respiratory and metabolic systems, other diseases involving lipid metabolism and various endocrine disorders as well as other metabolic or nutritional disorders. (cdc.gov)
  • Alanine aminotransferase measurements are used in the diagnosis and treatment of certain liver diseases (e.g., viral hepatitis and cirrhosis) and heart diseases. (cdc.gov)
  • AST measurements are used in the diagnosis and treatment of certain types of liver and heart disease. (cdc.gov)
  • BUN measurements are used in the diagnosis of certain renal and metabolic diseases. (cdc.gov)
  • Bilateral disease is typically infectious or allergic. (medscape.com)
  • This syndrome is synonymous with farmers' lung, mushroom workers' lung, bark strippers' disease, and allergic alveolitis. (cdc.gov)
  • The ongoing coronavirus disease 2019 (COVID-19) pandemic is associated with substantial morbidity and mortality. (nature.com)
  • Huntington's disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. (hdsa.org)
  • Huntington's disease affects a part of the brain called the striatum that we know is very important for controlling behavior. (hdsa.org)
  • In the early stages of HD, most of the disease in the brain is in the striatum. (hdsa.org)
  • This study aimed to determine the effects of the CXC chemokine ligand 16 (CXCL16)/CXC chemokine receptor 6 (CXCR6) pathway on cholesterol accumulation in the radial arteries of end-stage renal disease (ESRD) patients with concomitant microinflammation and to further investigate the potential effects of the purinergic receptor P2X ligand-gated ion channel 7 (P2X7R). (medsci.org)
  • Cardiovascular disease is the most common cause of death for patients with end-stage renal disease (ESRD). (medsci.org)
  • All performed tests were normal, thus excluding systemic disease. (nih.gov)
  • Very few dogs are affected with this autoimmune disease prior to 1 year of age. (vin.com)
  • Elevated levels of the transaminases can indicate myocardial infarction, hepatic disease, muscular dystrophy, or organ damage. (cdc.gov)
  • 9. A history of diseases affecting lymphoid organs (Hodgkin lymphoma, other lymphomas, leukemias, sarcoidosis). (who.int)
  • To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world. (asn-online.org)
  • Increased ALP activity is associated with two groups of diseases: those affecting liver function and those involving osteoblastic activity in the bones. (cdc.gov)
  • Classification can also be based on age of occurrence or course of disease. (medscape.com)
  • ESRD patients have an increased risk of cardiovascular death, 10-20 times that of the general public, and are more likely to die of cardiovascular disease than to progress to dialysis [ 1 ] . (medsci.org)
  • [ 2 ] Options for second-line therapy in patients with relapsed/refractory disease include chemotherapy-free regimens with biologic targeted agents such as covalent Bruton tyrosine kinase (BTK) inhibitors, lenalidomide,venetoclax, and chimeric antigen receptor (CAR) T-cell therapy. (medscape.com)
  • Small bowel metastases from primary carcinoma of the lung are very uncommon and occur usually in patients with terminal stage disease. (ispub.com)
  • Two patients with Erdheim-Chester disease with progressive cerebellar dysfunction and pyramidal signs are reported on. (bmj.com)
  • as monotherapy for the treatment of those patients who have received at least two chemotherapy regimens for their metastatic disease. (who.int)
  • Biocon Biologics Ltd), BT-ON014 - in combination with docetaxel for the treatment of those patients who have not received chemotherapy for their metastatic disease - in combination with an aromatase inhibitor for the treatment of postmenopausal patients with hormone-receptor positive MBC, not previously treated with trastuzumab. (who.int)
  • To make optimal use of available hospital resources, reasons that directly or indirectly contributed to the prolonged hospitalization of patients should be considered and addressed during future pandemics or disease outbreaks. (who.int)
  • This illness is called organic dust toxic syndrome (ODTS) and is syn- onymous with grain fever, silo unloaders' disease, inhalation fever, and toxic pneu- monitis. (cdc.gov)
  • These results demonstrate that effector target-guided engineering of NLR receptors can provide new-to-nature disease resistance in crops. (elifesciences.org)
  • Bronchoalveolar lavage samples demonstrate marked infiltration of polymorphonuclear leukocytes (13,14). (cdc.gov)