• Previous studies have identified multiple quantitative trait loci (QTL) controlling different aspects of disease pathogenesis. (biomedcentral.com)
  • Recent GWAS have mapped several CKD susceptibility loci. (trainckdis.eu)
  • Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma. (kaiserpermanente.org)
  • Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. (ox.ac.uk)
  • One such determinant is the potential involvement of genetic susceptibility loci to asthma after viral bronchiolitis, a critical area that is just beginning to be evaluated. (atsjournals.org)
  • Thus, we selected three widely-studied polymorphism loci (rs3213172, rs3213173, and rs3213176) to find a novel marker for the risk prediction of ovarian cancer. (hindawi.com)
  • Genome-wide association studies (GWAS) have now identified 235 inflammatory bowel disease (IBD)-associated susceptibility loci, substantially expanding our understanding of the biology underlying these diseases. (medscape.com)
  • Antimicrobial susceptibility testing was performed to determine the appropriate selection of antibiotics. (unair.ac.id)
  • Our aims were (1) to isolate and molecular type the causative agent, and (2) to determine antibiotic susceptibility in vitro so as to ensure the most appropriate antimicrobial therapy for the dog. (frontiersin.org)
  • If necessary, the microbiologist gives training in basic microbiology to ICC and antimicrobial stewardship members and provides expertise (e.g., quality of preanalytical phase, interpretation of culture and antimicrobial susceptibility results, ready to use microbiological strategies to deal with each specific infection control situation, evaluation of resources needed). (isid.org)
  • These species were validated primarily on the basis of DNA-DNA hybridization, 16S rRNA gene sequence analysis, antimicrobial susceptibility and biochemical profiles, and, to a lesser degree, on high-performance liquid chromatography ( 22 , 54 , 55 , 69 ). (antimicrobe.org)
  • N. farcinica is particularly important to distinguish since it has increased virulence and differs in its antimicrobial susceptibility test results and its epidemiology ( 16 , 126 ). (antimicrobe.org)
  • Reports have been limited to antimicrobial susceptibility test results of clinical isolates, usually from reference laboratories, animal studies and case summaries ( 19 , 78 ). (antimicrobe.org)
  • Examine the lessons learnt from pilot laboratory development programmes in two Pacific island nations that focused on establishing standard procedures for micrological diagnostics and antimicrobial susceptibility testing (AST) and on improving the training of clinicians to increase their use of laboratory services. (who.int)
  • Knowledge of bacterial antimicrobial susceptibility testing (AST) patterns is the cornerstone of an effective clinical and public health response to AMR. (who.int)
  • So far we have confirmed C5 as a putative susceptibility gene for the Cia2 locus on chromosome 2. (biomedcentral.com)
  • We also identified the mitochondrial ATP8 as a novel susceptibility gene. (biomedcentral.com)
  • The breast cancer 1 (Brca1) susceptibility gene regulates the repair of reactive oxygen species (ROS)-mediated DNA damage, which is implicated in neurodevelopmental disorders. (bvsalud.org)
  • Gene co-expression network-based methods have been widely used in processing microarray data and have especially been used to identify meaningful functional modules [ 18 , 19 ]. (biomedcentral.com)
  • Rapid molecular identification and typing methods that may be useful include 16S rRNA gene sequencing, random amplified polymorphic DNA and a combination polymerase chain reaction-restriction fragment length polymorphism analysis ( 39 , 116 ). (antimicrobe.org)
  • Nucleic acids, such as antisense oligonucleotides (AONs) and small interfering RNAs (siRNAs) have enormous potential as therapeutics for life-threatening diseases because in principle, any problematic gene can be targeted with high efficacy and sequence-specificity. (grstiftung.ch)
  • 2006) it would be good if that future epidemiological studies of relationships between lead exposures and cancer should include evaluation of genetic susceptibility factors, such as the ALAD gene. (who.int)
  • To explore work on gene-environment interaction (GxE) at the Centers for Disease Control and Prevention (CDC) and the Agency for Toxic Substances and Disease Registry (ATSDR), we examined the CDC-Authored Genomics and Precision Health Publications Database (CDC-Authored GPHPD) , which includes articles published by CDC/ATSDR authors since 2011. (cdc.gov)
  • More than half (23 of 39) of the articles represent epidemiologic studies including candidate gene and genome-wide association studies (GWAS) examining genetic effect modification on disease risk. (cdc.gov)
  • Here we describe the isolation, molecular typing, and antibiotic susceptibility testing of the causative agent of a rare case of generalized mycobacteriosis in a crossbred dog. (frontiersin.org)
  • The Public Health Laboratory Service receives antibiotic susceptibility data for bacteria from bloodstream infections from most hospitals in England and Wales. (uea.ac.uk)
  • The serogroup distribution, antibiotic susceptibility and antigenic and molecular characteristics of N. meningitidis isolates were determined in patients aged 3 days-13 years between February 1998 and June 2013. (who.int)
  • However, the less com- sporadic cases of meningococcal in- Antibiotic susceptibility mon septic shock with the classical pur- vasive diseases ( 13 ). (who.int)
  • The countries, serogroup A and B isolates are Antibiotic susceptibility was performed case-fatality rate of invasive disease is predominant. (who.int)
  • Epidemiological and experimental studies indicate that the progression of chronic kidney disease after an initial injury is genetically determined. (trainckdis.eu)
  • However, the genes and the genetic networks that account for the increased susceptibility to CKD progression remain mostly unidentified. (trainckdis.eu)
  • Awareness of this disease and its progression to its complication deep vein thrombosis is required to understand the burden of this disease. (unair.ac.id)
  • This research may offer the potential to intervene and halt the progression of disease. (sciencedaily.com)
  • 14 , 15 Furthermore, in two studies among adults with HIV not receiving ART, persons who developed TB disease had higher viral loads 16 and a greater risk of HIV disease progression 16 and death 17 than CD4-matched control patients without TB. (hiv.gov)
  • The risk of progression from LTBI to TB disease in persons with HIV is reduced both by ART and by treatment of LTBI. (hiv.gov)
  • 2 This was also reiterated by Jason Sheltzer, a scientist at Cold Spring Harbor Laboratory, who has been studying the role of ACE2 enzymes as a correlation in disease progression. (rdhmag.com)
  • In terms of the disease control rate (complete response + partial response + stable disease ratio), response rate (complete response + partial response ratio), median progression-free survival, and median time to progression, lenvatinib shows significantly better results compared with sorafenib, another oral multi-kinase inhibitor (75.5 vs. 60.5%, 24.1 vs. 9.2%, 7.4 vs. 3.7 months, 8.9 vs. 3.7 months, respectively) ( 7 ). (spandidos-publications.com)
  • Age of onset, disease severity, and rate of progression vary significantly among affected males. (nih.gov)
  • We are also learning more about the effects of inherited traits, such as blood type, on disease susceptibility and progression. (cdc.gov)
  • Most of the isolates represented fortuitous isolations, although recent- ly its identification has posed concerns about its possible clinical importance. (cdc.gov)
  • Culture coupled with 16S rRNA identification identified over 74 isolates for human oral taxa without previously cultivated representatives. (sciencedaily.com)
  • Meningococcal meningitis is the most of meningococcal meningitis ( 12 ) and lance of meningococcal disease accord- common entity and the outcome is Europe, where isolates of serogroup B ing to the guidelines of the Tunisian usually good if patients are rapidly and are predominant and responsible for Department of Health. (who.int)
  • Murine collagen-induced arthritis (CIA) is a chronic inflammatory disease bearing all the hallmarks of rheumatoid arthritis. (biomedcentral.com)
  • Asthma is a complex inflammatory disease projected to be caused by genetic mutation or other environmental factors. (sbwire.com)
  • As disease research depends heavily on genomic DNA sequencing techniques for the identification of genetic variants associated with disease occurrence, understanding genomic DNA's importance can enable advancements in diagnostics, personalized medicine, and genetic counseling services. (keydifference.info)
  • The current research is aimed at assessing the correlation between two functional GAS5 variants (rs145204276 and rs55829688) and susceptibility to IS in a Han Chinese population. (hindawi.com)
  • Variants in the GAS5 promoter region have been reported to be linked to mutiple diseases. (hindawi.com)
  • A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. (who.int)
  • [ 11-13 ] The most recent studies have undertaken low-coverage whole genome sequencing to interrogate low-frequency variants and define how much these variants contribute to IBD susceptibility. (medscape.com)
  • 3B: Discover polymorphisms in candidate genes for disease susceptibility and resistance in C. virginica and develop single nucleotide polymorphism (SNP) markers that can be genotyped in a high-throughput assay. (usda.gov)
  • Views on perceived susceptibility to and severity of tuberculosis varied widely and included many misconceptions. (itg.be)
  • By clarifying the roles of both host- (genetic) and virus- (environment) specific factors that contribute to the frequency and severity of viral LRTI, it may be possible to determine if severe LRTIs cause asthma, or if asthma susceptibility predisposes patients to severe LRTI in response to viral infection. (atsjournals.org)
  • It has also been determined that vaping or smoking can increase the risk of disease severity if an individual contracts SARS-CoV-2. (rdhmag.com)
  • The severity of activated PI3K-delta syndrome varies widely. (medlineplus.gov)
  • Identification of genes associated with oyster disease will provide markers that can be used to enhance and accelerate the development of high-performing oyster lines through selective breeding and will support the East Coast shellfish aquaculture industry. (usda.gov)
  • The molecular techniques (16S rDNA PCR and sequencing), and mass spectrometry appear as attractive methods for reliable identification to the genus. (wikipedia.org)
  • Many aspects regarding the molecular mechanisms of small heat shock proteins, both in health and disease, remain to be unraveled. (uantwerpen.be)
  • The use of molecular technology for identification and epidemiologic subtyping of the Nocardia species has been limited by the lack of simple and rapid assays. (antimicrobe.org)
  • Despite being a relatively common disease, the precise molecular mechanisms for the onset of ischemic stroke (IS) are still incompletely understood, with both environmental and genetic factors being implicated in this disease in a complex manner. (hindawi.com)
  • Emerging Infectious Diseases, 8 (5). (uea.ac.uk)
  • In line with the recommendations of the Asia Pacific technical Advisory Group (tAG) on Emerging Infectious Diseases and in response to requests from Member States, the WHO Western Pacific regional office has developed the following guide for the design of event-based surveillance systems. (who.int)
  • In contrast to epilepsy, sleep abnormalities are among the first noticeable symptoms of the disease. (uantwerpen.be)
  • Inflammatory bowel diseases (IBD) refer to a group of inflammatory conditions concerning colon and small intestine, which cause socially uncomfortable symptoms and often are associated with an increased risk of colon cancer. (biomedcentral.com)
  • Inflammatory bowel diseases (IBD) are a group of inflammatory conditions concerning colon and small intestine, which cause socially uncomfortable gastrointestinal symptoms. (biomedcentral.com)
  • Its lethality is a consequence of the lack of symptoms or biomarkers enabling the early diagnosis of disease, and the propensity of malignant cells to seed the peritoneal cavity. (biomedcentral.com)
  • patients may present with many years of symptoms or with acute, life-threatening disease. (medscape.com)
  • Early diagnosis and careful treatment tailored to individual patient symptoms have improved the prognosis in what was once perceived as an often-fatal disease. (medscape.com)
  • However, a majority of lower income countries do not have microbiological diagnostic testing for prompt, reliable confirmation of bloodstream infection and identification of AMR. (who.int)
  • The identification is carried out through various biochemical tests, used for the identification of Gram-negative bacterial species, and rapid determination of enzymatic reactions. (wikipedia.org)
  • The incidence rate of asthma is rising among children due to increasing susceptibility to various airborne allergens and other associated risk factors. (sbwire.com)
  • According to a 1993 report titled "Indoor Allergies," published by the Institute of Medicine (IOM), airborne fungal allergens were most often associated with allergic diseases, such as allergic rhinitis/conjunctivitis, allergic asthma, and hypersensitivity pneumonitis. (floridabar.org)
  • 2), birth defects caused by thalidomide (3), chron- acterize chemical respiratory allergens are best ic diseases associated with occupational expos- described as being still under development (11, ures, for example to vinyl chloride (4), and the 12). (cdc.gov)
  • Therefore, we used an event-history with risk-free model to simultaneously characterize alcoholism susceptibility and onset age in 65 independent non-Hispanic Caucasian males in the Collaborative Study on the Genetics of Alcoholism. (nature.com)
  • Whole genome sequencing (WGS) is widely used to characterize microbial genomes. (biomedcentral.com)
  • The Centers for Disease Control and Prevention (CDC) stopped tracking cases of e-cigarette or vaping-associated lung injury (EVALI) in February 2020, as cases had drastically dropped off from their peak in September 2019. (rdhmag.com)
  • Uptake in screening use in states can be influenced by Medicaid coverage and eligibility policies, public health outreach efforts, and the Centers for Disease Control and Prevention-funded National Breast and Cervical Cancer Early Detection Program. (cdc.gov)
  • Sequence-based predictive systems, based on identifying patterns in peptides with experimentally determined binding strength, are widely used to facilitate the identification of binding peptides to MHC class II molecules. (biomedcentral.com)
  • Genomic DNA is passed from parent to child during reproduction and determines their physical characteristics, susceptibilities to diseases, and predispositions. (keydifference.info)
  • Genomic DNA serves as an indispensable repository of genetic information that determines an organism's characteristics, susceptibility to illness, and overall characteristics of life forms. (keydifference.info)
  • However, they suffer from low bioavailability due to their poor permeation characteristics and susceptibility to degradation by nucleases. (grstiftung.ch)
  • However, cell lines are known for their susceptibility to genetic and metabolic alterations, which can alter their characteristics in relation to the primary malignant cells. (biomedcentral.com)
  • Social stigma in the context of health is the negative association between a person or group of people who share certain characteristics and a specific disease. (who.int)
  • People who don't have the disease but share other characteristics with this group may also suffer from stigma. (who.int)
  • Oral delivery of nucleic acid drugs to the colon would be highly desirable to provide new options for the treatment of serious and rare colonic diseases such as ulcerative colitis, Crohn's colitis, and Lynch syndrome, but has been challenging due to the harsh conditions found in the gastrointestinal tract and low cellular uptake. (grstiftung.ch)
  • In particular, Crohn's Disease (CD) and Ulcerative Colitis (UC) present the highest incidence in population and are associated with an increased risk for colon cancer [ 1 ]. (biomedcentral.com)
  • Methods A Medline search including items 'intestinal microbiota/microbiome', 'inflammatory bowel disease', 'ulcerative colitis', 'Crohn's disease', 'faecal microbial transplantation', 'dietary manipulation' was performed. (medscape.com)
  • This approach has identified a missense variant in ADCY 7, with mechanistic interpretation being that loss of function reduces cAMP production leading to an excessive inflammatory response that predisposes to ulcerative colitis but not Crohn's disease (CD). (medscape.com)
  • The bacterial species Streptococcus mutans is widely recognized as the primary pathogen in early childhood caries. (sciencedaily.com)
  • Infectious Disease Reports , 12 , Article e8725. (unair.ac.id)
  • Effendy, L, Octora, M & Kusumaningrum, D 2020, ' A case of deep vein thrombosis associated with methicillin sensitive Staphylococcal aureus genu septic arthritis ', Infectious Disease Reports , vol. 12, e8725. (unair.ac.id)
  • Early childhood caries, ECC, is the most common chronic infectious disease of childhood in the United States. (sciencedaily.com)
  • Tuberculosis (TB) (see the image below), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease-related mortality worldwide. (medscape.com)
  • The National Institute of Occupational Safety and Health (NIOSH) and the National Center for Emerging Zoonotic and Infectious Disease (NCEZID) contributed the most with 12 and 8 articles, respectively. (cdc.gov)
  • Septic arthritis caused by bacteria Gram positive Staphylococcus aureus (S. aureus) infection has been widely reported from Europe and the United States. (unair.ac.id)
  • Dental caries is caused by an interaction between bacteria, host susceptibility and a carbohydrate diet that contains large amounts of sugar. (sciencedaily.com)
  • 3C: Identify Single Nucleotide Polymorphisms (SNPs) associated with disease-susceptible and disease-resistant phenotypes in C. virginica. (usda.gov)
  • In addition, a number of different genetic determinants of IS risk have been identified in genome-wide association studies, with single-nucleotide polymorphisms (SNPs) in 9p21, PITX2, HDAC9, ABO, NINJ2, ALDH2, and TSPAN2, all being linked with stroke susceptibility [ 2 ]. (hindawi.com)
  • So far, the studies which explore the relationship between the E2F1 polymorphisms and ovarian cancer susceptibility are rare. (hindawi.com)
  • Although this association has been widely reported, the mechanisms underlying this increased incidence of wheezing after severe bronchiolitis are unclear. (atsjournals.org)
  • These medications can prevent severe disease, hospitalization, and death and are widely available but have been underused. (cdc.gov)
  • It is now widely appreciated that the environmental microbiome, composed of microbial communities associated with soil, water, atmosphere, and the built environment, impacts immune system development and susceptibility to immune-mediated disease 6 , 7 , 8 . (medrxiv.org)
  • MAC infections may cause granulomatous diseases, which range from localized granulomas to disseminated diseases. (frontiersin.org)
  • The strategy is based on integrating a genome scan to identify QTLs linked to clinical disease phenotypes and subtraits in a cross between the CIA-susceptible DBA1/J and resistant FVB/NJ mouse strains. (biomedcentral.com)
  • Together these findings suggest that clinically significant occult heart disease may be relatively common and represent a risk factor for an adverse clinical outcome. (vin.com)
  • Serogroup A strains are by the disc diffusion method and in- ~10% in treated cases but varies widely homogeneous and have the same an- cluded penicillin G, amoxicillin, cefo- depending on the clinical presentation tigenic formula, A:4:P1.9 ( 2 , 10 , 11 , 14 ), taxime, chloramphenicol and rifampin. (who.int)
  • However, the clinical presentation widely varies. (medscape.com)
  • Pulmonary disease is the major cause of morbidity and mortality in CF. (nih.gov)
  • Pulmonary disease manifests as pulmonary hemorrhage, fibrosis, or infarct. (medscape.com)
  • Case-control genetic association studies typically ignore possible later disease onset in currently healthy subjects and assume that subjects with diseases equally contribute to the likelihood for inference, regardless of their onset age. (nature.com)
  • Using these methods to analyse a dichotomous disease event alone ignores the probability of later disease onsets in currently healthy subjects and incorrectly considers that all subjects with diseases equally contribute to the likelihood for inference, irrespective of differences in their onset age. (nature.com)
  • Pesticide exposure is linked to cancers, asthma, neurodevelopmental disorders like autism and ADHD and to adult neurological diseases like Alzheimer's and Parkinson's. (foe.org)
  • CIA has been widely used to study the etiology, pathogenesis and new therapeutic approaches of rheumatoid arthritis. (biomedcentral.com)
  • Here we present preliminary data using an integrative genomics strategy to identify new putative susceptibility genes contributing to the pathogenesis of CIA. (biomedcentral.com)
  • Normally found in the oropharyngeal tract of mammals, they are involved in the pathogenesis of some animal bite wounds and periodontal diseases. (wikipedia.org)
  • In one case, the liver failure was considered to be due to advanced hepatitis or cirrhosis, but rheumatic heart disease was also present. (cdc.gov)
  • This previously unknown mitochondrial function of HSPB1 is disturbed by CMT disease-causing mutations. (uantwerpen.be)
  • A definitive diagnosis depends on the isolation and the identification of Nocardia species. (antimicrobe.org)
  • Further studies are required to identify barriers and facilitators to the improved identification and management of tuberculosis in hard-to-reach populations to inform recommendations for more effective tuberculosis control programmes. (itg.be)
  • Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. (encyclopedia.com)
  • Tuberculosis spread much more widely in Europe when the industrial revolution began in the late nineteenth century. (encyclopedia.com)
  • TB disease (defined as clinically active disease, often with positive smears and cultures) can develop soon after exposure to M. tuberculosis organisms (primary disease) or after reactivation of latent infection. (hiv.gov)
  • Cystic fibrosis (CF) is a multisystem disease affecting epithelia of the respiratory tract, exocrine pancreas, intestine, hepatobiliary system, and exocrine sweat glands. (nih.gov)
  • No organ is spared from the effects of this multisystem disease. (medscape.com)
  • With the development of markedly improved living standards throughout society, coronary artery disease (CAD) has emerged as a leading factor of mortality, functional deterioration, skyrocketing healthcare expenditure, disability and morbidity. (biomedcentral.com)
  • There is currently no specific data that links the types of the diseases and mortality to use of tobacco. (who.int)
  • The Centers for Disease Control in recent congressional testimony has attempted to set forth some basic general findings upon which it contends there is general agreement. (floridabar.org)
  • The authors say their findings could be used for interpreting medical scans of spinal disease. (biomedcentral.com)
  • Feline herpesvirus 1 (FHV-1) is a DNA virus that produces mainly upper respiratory tract disease in cats. (vin.com)
  • Mycoplasma ovipneumoniae is a critical pathogen that causes respiratory diseases that threaten Caprini health and cause economic damage. (biomedcentral.com)
  • Remarkably, our recent data showed that the predisposition to develop renal lesions after UUO varies widely among 16 strains of mice. (trainckdis.eu)
  • The human microbiome has been linked to individual COVID-19 disease outcomes 9 , but there are limited data on the influence of the environmental microbiome on geographic variation in COVID-19 across populations 10 . (medrxiv.org)
  • Also, often it is difficult to compare in vitro susceptibility results with data reported by other investigators because of differences in methodology, e.g., lack of interlaboratory standardization of inocula (e.g.,104 versus102 CFU/ml), and use of a broth microdilution method versus agar dilution or disk diffusion methods. (antimicrobe.org)
  • DISPATCHES diagnosis of chronic granulomatosis disease was excluded. (cdc.gov)
  • The estimated annual risk of developing TB disease among persons with LTBI (diagnosed by a positive tuberculin skin test [TST] or interferon gamma release assay [IGRA] in the absence of a TB disease diagnosis) is 3 to 12 times greater for untreated people with HIV than for those without HIV. (hiv.gov)
  • Therefore, improving the early diagnosis rate, chemotherapy drug sensitivity, reducing tumor recurrence, and improving disease prognosis are the focus of diagnosis and treatment research at the present stage [ 8 , 9 ]. (hindawi.com)
  • We have entered the "omics" era, which now allows us to undertake large-scale/high-throughput microbiota analysis which may well define how we approach diagnosis and treatment of inflammatory bowel disease (IBD) in the future, with a strong steer towards personalised therapeutics. (medscape.com)
  • Strategies using genomics and proteomics give hope for identification of biomarkers that can be used for early disease detection and treatment. (medscape.com)
  • For E. coli, ciprofloxacin resistance rose from 0.8% in 1990 to 3.7% in 1999 and became widely scattered among reporting hospitals. (uea.ac.uk)
  • Coffee breeding for rust resistance has been one of the most suitable and sustainable strategies for controlling the disease. (mdpi.com)
  • In those with early progressive disease, CNS involvement (manifest primarily by progressive cognitive deterioration), progressive airway disease, and cardiac disease usually result in death in the first or second decade of life. (nih.gov)
  • Osler was the first physician who recognized that systemic features of the disease could occur without skin involvement. (medscape.com)
  • Entire organizations were set up to study not only the disease as it affected individual patients, but its impact on the society as a whole. (encyclopedia.com)
  • Many elderly patients developed the infection some years ago when the disease was more widespread. (encyclopedia.com)
  • As patients continue to improve and survive, physicians now must assess patients for long-term disease sequelae, such as atherosclerosis, and develop prevention strategies. (medscape.com)
  • Patients with immune complex disease in the kidneys may present with nephritis or nephrotic syndrome. (medscape.com)
  • In parallel, this research allowed the identification of other local nucleic acid delivery strategies for the treatment of intestinal diseases. (grstiftung.ch)
  • This could help clinicians investigate an individual's vertebral shape and predict their susceptibility to intervertebral disc herniation. (biomedcentral.com)
  • The identification at the species level remains difficult when a single method is used. (wikipedia.org)
  • Phylogenetic analysis supported the morphological identification of the rodents and revealed a marked genetic difference between the two heterospecific species. (microbial-ecology.net)
  • This suggests that other species such as S. wiggsiae are also disease causing pathogens. (sciencedaily.com)
  • In particular, a loss of species richness in Crohn's disease has been widely observed. (medscape.com)
  • Traditional microbiologic methods remain suboptimal in providing rapid identification and susceptibility testing. (isid.org)
  • Some individuals progress to end-stage renal disease (ESRD) later in life. (nih.gov)
  • For children with renal disease, recognition of the steroid-sparing effect of immunosuppressive agents, such as azathioprine, mycophenolate, and cyclophosphamide, has greatly improved kidney organ survival and outcome. (medscape.com)
  • The Tripartite Zoonoses Guide (TZG) has been jointly developed by the FAO, OIE, and WHO to support countries in taking a multisectoral, One Health approach to address zoonotic diseases. (who.int)
  • IBD are complex disorders, which rely on genetic susceptibility, environmental factors, deregulation of the immune system, and host relationship with commensal microbiota. (biomedcentral.com)
  • Disparity on the sex hormones and stress adaptation may augment fatigue susceptibility. (ui.ac.id)
  • Because of its protean manifestations, lupus must be considered in the differential diagnoses of many conditions, including fevers of unknown origin, arthralgia, anemia, new-onset kidney disease, psychosis, and fatigue. (medscape.com)
  • In addition to the disease status, we often acquire additional phenotype information of subjects, such as the age of onset, which provides the time to determine disease development in subjects. (nature.com)
  • To fill the lack of a reference resource for 'omics' science analysis in the context of IBD, we developed the IBDsite (available at http://www.itb.cnr.it/ibd ), a disease-oriented platform, which collects data related to biomolecular mechanisms involved in the IBD onset. (biomedcentral.com)