Disease free survival of patients nasopharyngeal neoplasms. Medical search. Frequent questions

Nasopharyngeal carcinoma (NPC) with local persistence after primary radiotherapy carries a high risk of treatment failure. (nih.gov)
We investigated the clinical significance of plasma concentrations of Epstein-Barr virus (EBV) DNA in patients with advanced nasopharyngeal carcinoma. (nih.gov)
Ninety-nine patients with biopsy-proven stage III or IV nasopharyngeal carcinoma and no evidence of metastasis (M0) received 10 weekly chemotherapy treatments followed by radiotherapy. (nih.gov)
Quantification of plasma EBV DNA is useful for monitoring patients with nasopharyngeal carcinoma and predicting the outcome of treatment. (nih.gov)
Nasopharyngeal carcinoma (NPC) is a rare head and neck neoplasm worldwide. (intechopen.com)
Nasopharyngeal carcinoma (NPC) is a rare disease and one of the most common types of malignancies that appear in the nasopharynx, which is the narrow tube passage behind the nasal cavity and one of the malignancies associated with the Epstein-Barr virus (EBV) and is considered one of the malignant and rare tumors in most parts of the world and is distinguished by distribution geographical and ethnic [ 1 ]. (intechopen.com)
The US Food and Drug Administration (FDA) has approved toripalimab-tpzi (Loqtorz, Coherus BioSciences) in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic or recurrent locally advanced nasopharyngeal carcinoma. (medscape.com)
The FDA also approved toripalimab , a programmed death receptor 1-blocking antibody, as a single agent for recurrent unresectable or metastatic nasopharyngeal carcinoma with disease progression on or after a platinum-containing chemotherapy. (medscape.com)
Efficacy of toripalimab as a single agent was evaluated in the POLARIS-02 study in 172 patients with unresectable or metastatic nasopharyngeal carcinoma who had received prior platinum-based chemotherapy or had progressed within 6 months of its completion in the neoadjuvant, adjuvant, or definitive chemoradiation setting. (medscape.com)
The recommended dose as a single agent for previously treated nasopharyngeal carcinoma is 3 mg/kg every 2 weeks until disease progression or unacceptable toxicity. (medscape.com)
Cite this: FDA Approves Toripalimab for Nasopharyngeal Carcinoma - Medscape - Oct 30, 2023. (medscape.com)
Adrenocortical tumors encompass a spectrum of diseases with often seamless transition from benign (adenoma) to malignant (carcinoma) behavior. (oncolink.org)
Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). (oncolink.org)
He underwent excision biopsy which was reported as non- keratinizing nasopharyngeal carcinoma. (bvsalud.org)
Excision of the lesion was done and histopathological and immunohistochemical analysis revealed it to be metastasis from SMARCB1 deficient sinonasal carcinoma and not nasopharyngeal carcinoma as diagnosed from the other center. (bvsalud.org)
The aim of the study was to clinically validate the new staging system in predicting the outcome in patients treated for carcinoma oral tongue. (bvsalud.org)
Methods: We studied 70 patients with squamous cell carcinoma of the oral tongue who underwent primary surgical treatment at a tertiary care center in the year 2012. (bvsalud.org)
SOX9 promotes nasopharyngeal carcinoma cell proliferation, migration and invasion through BMP2 and mTOR signaling. (cancerindex.org)
However, the role of SOX9 in nasopharyngeal carcinoma (NPC) remains unknown. (cancerindex.org)
Subsequent studies revealed that EBV caused a number of different human malignancies, such as nasopharyngeal carcinoma (NPC), Hodgkin's lymphoma, extranodal NK/T-cell lymphoma, nasal type and lymphoproliferative disorders of immunocompromised hosts ( 2 ). (spandidos-publications.com)
FDG PET and CT/MRI scanning were performed at the initial staging and/or the follow-up in 24 patients with rare HNCs, 10 with melanoma, 9 with sarcoma, 3 with olfactory neuroblastomas, and 2 with basal cell carcinoma. (e-ceo.org)
Patients with squamous cell carcinoma, lymphoma, thyroid cancer, salivary gland cancer, nasopharyngeal carcinoma, metastatic lesion with primary tumor outside the head and neck, and metastasis from unknown primary squamous cell carcinoma or adenocarcinoma were excluded, as were patients not assessed by FDG PET prior to treatment or during follow-up and patients with inadequate follow-up information. (e-ceo.org)
The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma. (uchicago.edu)
Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma. (uchicago.edu)
Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. (uchicago.edu)
Risk of second primary malignancy after nasopharyngeal carcinoma in the United States: A population-based study. (uchicago.edu)
Disease-free survival after salvage therapy for recurrent oropharyngeal squamous cell carcinoma. (uchicago.edu)
The prognosis of advanced nasopharyngeal carcinoma (NPC) patients after intensity-modulated radiotherapy (IMRT) has not been well studied. (qxmd.com)

Fifty-two patients (7%) had persistent local disease, but seven of them were unsuitable for radiotherapy boost. (nih.gov)
0.001) than patients with undetectable EBV DNA one week after the completion of radiotherapy. (nih.gov)
At a time when modern radiation treatment like intensity-modulated radiotherapy (IMRT) are accomplishing great good local control, distant metastases are getting to be the transcendent design of treatment failure, particularly in patients with locally progressed illness. (intechopen.com)
In patients with nonseminoma, first-line radiotherapy indicated superior OS and PFS (P=0. (baugeschaeft-roblick.de)
He was referred to our center with residual disease in spheno-ethmoidal recess for which radiotherapy was given. (bvsalud.org)
After completion of radiotherapy, the primary site had no residual disease, but while on follow-up he developed left sided neck nodes within 4 months of completion of treatment. (bvsalud.org)
Radiotherapy is equally as effective in the palliation of dysphagia (difficulty swallowing) as chemoradiotherapy for patients with advanced esophageal cancer, according to a phase III study presented at the 56th American Society for Radiation Oncology (ASTRO) Annual Meeting-offering clinicians an option to relieve this common complication without the added toxicity of chemotherapy. (oncnursingnews.com)
Patients who received radiotherapy alone reported a dysphagia response of 67.89% at any point compared with a 73.87% response with chemoradiotherapy ( P = .343). (oncnursingnews.com)
In this international multicenter trial, 220 patients were randomized to palliative radiotherapy (n = 109) or concomitant chemoradiotherapy with cisplatin and 5-FU (n = 111). (oncnursingnews.com)
Radiotherapy was administered at 35 Gy in 15 fractions to 115 patients in Australia and New Zealand and 30 Gy in 10 fractions to 105 patients in Canada and the United Kingdom. (oncnursingnews.com)
Best Practice in Advanced Oesophageal Cancer: A Report on TROG 03.01 NCIC CTG ES.2 Multinational Phase III Study in Advanced Oesophageal Cancer (OC) Comparing Quality of Life (QoL) and Palliation of Dysphagia in Patients Treated With Radiotherapy (RT) or Chemoradiotherapy (CRT). (oncnursingnews.com)
Therefore, knowing the genetic variations (polymorphisms) will be effective in predicting the response to treatment, and accordingly, we can determine which patients will benefit from chemo- or radiotherapy (Ansell et al. (researchsquare.com)
If radiotherapy improves survival and quality of life in cancer patients, then we should keep using it. (endalldisease.com)
Today, up to 60% of cancer patients receive radiotherapy as a part of their treatment regimens 1 and yet most are never fully aware of the risks involved with exposure to ionizing radiation. (endalldisease.com)
Radiation necrosis can occur when radiotherapy is used to treat primary CNS tumors, metastatic disease, or head and neck malignancies. (medscape.com)
We investigated the clinical characteristics of patients who developed thyroid dysfunction and evaluated the risk factors for hypothyroidism following radiotherapy and chemotherapy in pediatric patients with medulloblastoma or primitive neuroectodermal tumor (PNET). (e-apem.org)
Since survival rates markedly increased over the last 4 decades, leading to 70%-85% of cure rate in pediatric patients with medulloblastoma or PNET [ 3 ], regular monitoring of long-term complications related to radiotherapy and chemotherapy is needed to improve quality of life. (e-apem.org)
Since thyrotoxic and hypothyroid patients following head and neck irradiation therapy were firstly reported in the 1920s, and in the 1960s, respectively [ 4 ], thyroid dysfunction after radiotherapy has been reported in several studies [ 5 - 7 ]. (e-apem.org)

In the majority of cases, GF tumors are manifestations of the genetic disease, familial adenomatous polyposis (FAP), or its variant, the Gardner syndrome (GS). (wikipedia.org)
Partially or totally inactive APC protein in FAP allows the excessive intracellular accumulation of β-catenin and thereby promotes development of the tumors, cancers, and other manifestations of this disease. (wikipedia.org)
Mar 17, 2021 · PURPOSE The classification of the International Germ-Cell Cancer Collaborative Group (IGCCCG) has been a major advance in the management of germ-cell tumors, but relies on data of only 660 patients with seminoma treated between 1975 and 1990. (baugeschaeft-roblick.de)
Digital palpation of the soft palate may reveal a mass effect in cats with nasopharyngeal tumors. (vin.com)
SMARCB1 deficient sinonasal carcinomas are rare neoplasms, classified under sinonasal undifferentiated carcinomas by the fourth edition of the World Health Organization (WHO) classification of head and neck tumors. (bvsalud.org)
Given the importance of early diagnosis in treating early tumors, knowledge of the demographic and pathological findings of the disease is helpful. (magiran.com)
SBRT combined with chemotherapy for the treatment of locally advanced pancreatic cancer can effectively control local tumors and alleviate local symptoms, prolong the overall survival of patients, and has tolerable toxicity ( 16 - 19 ). (frontiersin.org)
The overall accuracies of FDG PET and CT/MRI were 92% and 79%, respectively, for detecting primary tumors and 91% and 74%, respectively, for nodal metastases, but the differences were not significant due to the small number of patients. (e-ceo.org)
FDG PET may be useful for staging, posttreatment monitoring, and detection of distant metastases and second primary tumors in patients with rare HNCs. (e-ceo.org)
Due to the higher glycolytic rates of many neoplasms relative to normal tissue, the glucose analog 18 F-fluorodeoxyglucose (FDG) can be used to detect tumors, and positron emission tomography (PET) using FDG has been utilized in patients with HNCs for initial staging, management of recurrent cancers, and therapeutic monitoring ( 2 - 5 ). (e-ceo.org)
Although studies of salivary cancers, melanomas, basal cell carcinomas, and sarcomas arising in the head and neck region have suggested that FDG PET may be clinically useful in the staging, histologic grading, and post-treatment monitoring of patients with these tumors ( 10 - 13 ), the role of FDG PET in rare HNCs is still unclear, due to the rarity of these cancers. (e-ceo.org)
Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. (uchicago.edu)
However, a number of common side effects quickly became known, including burns, skin disease and the formation of tumors, but society failed to take these warnings seriously and by 1922, over 100 radiologists and many others working in the medical industry had died from cancer caused by x-rays. (endalldisease.com)

The consistent genotyping of EBV DNA between paired samples of plasma and primary tumor suggested that the circulating cell-free EBV DNA may originate from the primary tumor. (nih.gov)
There is variability in clinical signs based on whether there is a nasal or nasopharyngeal tumor present. (vin.com)
When cells in some area of the body duplicate without control, the excess of tissue develops called tumor or neoplasm. (solutionpharmacy.in)
It is not a rare clinical scenario to have patients presenting with coexisting malignant tumor and tuberculosis. (biomedcentral.com)
massive spinal ependymoma is a rare, benign, slow-growing tumor, and patients present symptoms years before diagnosis. (magiran.com)
In terms of tumor invasiveness, 13 (92.9%) patients were invasive and one (7.1%) patient was in situ. (magiran.com)
This study showed that SBRT can significantly reduce pain, effectively control local tumor progression, and have acceptable toxicity for patients with locoregional recurrence after radical resection of primary pancreatic cancer. (frontiersin.org)
The association between the PET results and the clinicopathologic parameters predicting tumor invasion, histologic grade and disease-free survival (DFS), was assessed. (e-ceo.org)
A total of 9881 patients across 33 tumor types from The Cancer Genome Atlas database were included in this study. (thno.org)
Moreover, based on the proposed classification and therapeutic implications, an open website was established to provide tumor patients with comprehensive information on inflammasome signaling. (thno.org)
Almost half of patients present with extension of the tumor beyond the soft palate. (medscape.com)

Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
Head and neck cancer (HNC) is a heterogeneous group of malignant neoplasms, and its classification is a challenge. (eurekaselect.com)
Nonsquamous cell cancers, including minor salivary gland cancers, sarcomas, and melanomas, account for the other half (see the histologic distribution of hard palate malignant neoplasms and the histologic types and frequencies of minor salivary gland neoplasms of the palate below). (medscape.com)

This disease has peculiarities in its etiopathogenesis, presentation, risk of nodal and distant metastasis, response to therapy and overall survival (OS) outcomes that stand out as compared to other head and neck cancer subsites. (intechopen.com)
In terms of lymph node metastasis, it was observed in only one patient. (magiran.com)
Approximately 30% of patients have cervical node metastasis at the time of presentation. (medscape.com)

All these patients were restaged pathologically according to the new AJCC eighth staging system. (bvsalud.org)
Restaging of cases based on the eighth edition AJCC staging manual resulted in significant upstaging with difference in survival. (bvsalud.org)
We therefore evaluated the role of FDG PET for staging and monitoring patients with rare HNCs, including melanomas, basal cell carcinomas, sarcomas, and olfactory neuroblastomas (esthesioneuroblastomas). (e-ceo.org)
This "staging" process has historically assigned patients using traditional classifications which were established decades ago when, like other pediatric malignancies, the more extensive involvement of the cancer for a patient directly correlated with the patient's long term survival[[1]](#ref-0001). (authorea.com)

This lack of knowledge also prevented clinicians from gathering meaningful information about the natural history of the disease and its prognosis. (medscape.com)
Patients with HPV-positive HNC have a better prognosis compared to patients with HPV-negative HNC. (moffitt.org)
In fact, in this group of patients with a good prognosis, the risk of long term toxicities may outweigh the benefit of aggressive treatment. (moffitt.org)

Many advances in RT techniques and schedules are attempted to improve outcomes of the disease starting from intracavitary brachytherapy, intensity modulated RT to simultaneous modulated accelerated RT, all showing some promise with most significant benefit seen with addition of chemotherapy, especially in intermediate (Stage II) and advanced (Stage III, IVA, IVB) cases. (intechopen.com)
The first-line approval was based on the JUPITER-02 trial in 289 patients who had not received previous systemic chemotherapy for recurrent or metastatic disease. (medscape.com)
Neutrophilic eccrine hidradenitis (NEH) is a neutrophilic dermatosis primarily affecting the eccrine glands and occurs most commonly in patients undergoing chemotherapy for a malignancy. (annals.edu.sg)
This retrospective and single-center analysis included NSCLC patients who received a combination of chemotherapy and immunotherapy at the Department of Oncology at Shanghai Lung Hospital. (qxmd.com)
Two cases entered CR and one case required further chemotherapy for relapsed disease. (hku.hk)
Lead author Michael Penniment, MBBS, MBA, FRANZCR, noted that chemotherapy is commonly administered to patients with advanced esophageal cancer based on standard practice for less advanced disease. (oncnursingnews.com)
these patients can be spared the extra toxicity and cost of chemotherapy," said Penniment, who is director of radiation oncology at the Royal Adelaide Hospital and the Alan Walker Cancer Care Centre in Australia. (oncnursingnews.com)
Because a high percentage of these cancer patients are diagnosed in advanced stages, the treatment is increasingly invasive, including surgery, radiation therapy, or chemotherapy applied in isolation or in association with other treatment, depending on the tumor's site, histological degree, clinical stage, and the patient's physical condition 1 . (bvsalud.org)
It may be seen in greater than 90% of patients older than 60 years who have been successfully treated with combination chemotherapy and whole-brain radiation. (medscape.com)
For some high-risk patients, high-dose chemotherapy with autologous stem cell rescue (HDCT/ASCR) is indicated [ 2 ]. (e-apem.org)

3 months and the 1-year survival rate after recurrence was 23. (baugeschaeft-roblick.de)
Recurrence in the liver or the central nervous system was a major adverse prognostic factor, with a 5-year overall survival rate of 7% (95% CI, 1-32%), compared with 58% (95% CI, 33-79%) in patients who had lymph node, lung , or bone recurrences. (baugeschaeft-roblick.de)
To investigate how socioeconomic position (SEP) influences the effectiveness of cancer-directed treatment in premenopausal breast cancer patients in terms of breast cancer recurrence and mortality. (biomedcentral.com)
Even after radical resection, most patients will still have local and/or metastatic recurrence within 2 years ( 3 , 4 ), and the 5-year survival rate is only 20-25% ( 5 ). (frontiersin.org)
Symptoms of local recurrence include pain, bowel obstruction, portal hypertension, biliary obstruction, and malnutrition, which severely affect patients' quality of life ( 7 ). (frontiersin.org)
Follow-up FDG PET correctly diagnosed locoregional recurrence in all 12 patients, as shown by biopsy, and distant metastases in 6 patients. (e-ceo.org)

Berstein L, Gurney JG: Carcinomas and other malignant epithelial neoplasms. (oncolink.org)
Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)

Mar 22, 2022 · Lung cancer diagnosis innovation leads to higher survival rates Nov. Key Statistics for Testicular Cancer . (baugeschaeft-roblick.de)
Feb 28, 2022 · Lung cancer survival rates are most often given as 5-year or relative 5-year survival . (baugeschaeft-roblick.de)
Research shows that factors such as age, sex, smoking status, and type of cancer may influence survival rates . (baugeschaeft-roblick.de)
A relative survival rate compares people with the same type and stage of cancer to people in the overall population. (baugeschaeft-roblick.de)
Survival for all stages of lung cancer . (baugeschaeft-roblick.de)
May 10, 2023 · For the study, researchers analyzed data from the National Cancer Database on more than 30,000 non-small-cell lung cancer patients who were diagnosed and treated between 2012 and 2018. (baugeschaeft-roblick.de)
May 19, 2023 · Treatment with olaparib and durvalumab did not meet the prespecified target for 12-week disease control rate , however, it demonstrated potential for improved overall survival in patients with pretreated small cell lung cancer . (baugeschaeft-roblick.de)
The 5-year survival rate for small cell lung cancer is 3%, and 8% for non-small cell lung cancer (NSCLC). (baugeschaeft-roblick.de)
The survival rate is higher for people diagnosed with early-stage cancer and lower for those. (baugeschaeft-roblick.de)
Survival rates for lung cancer depend on the stage (extent) of the cancer , as well as other factors. (baugeschaeft-roblick.de)
Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. (oncolink.org)
In the Brazilian cases, the patients' families do not exhibit a high incidence of cancer, and a single, unique mutation at codon 337 in exon 10 of the TP53 gene is consistently observed. (oncolink.org)
Incredible advancements in cancer screening, early detection and treatments mean that more patients with cancer are living longer. (biomedcentral.com)
The future challenges are to understand how DNA-PKcs activity is correlated with cancer susceptibility and to identify those patients who would most benefit from DNA-PKcs inhibition. (amegroups.org)
The early stages of cervical cancer may be completely free of symptoms. (wikipedia.org)
Patients with locoregional recurrent pancreatic cancer after surgery treated with SBRT in our institution were retrospectively investigated from January 2010 to January 2020. (frontiersin.org)
Pancreatic cancer is a deadly disease with a 5-year survival rate of less than 9% ( 1 ). (frontiersin.org)
I am now repositioned to offer my patients the most recent and proven best standards in breast cancer treatment. (esmo.org)
The diagnosis of head and neck cancer is based on clinical and instrumental examinations, which may or may not confirm the suspected disease. (gsdinternational.com)
Professional oncology social workers provide free emotional and practical support for people with cancer, caregivers, loved ones and the bereaved. (cancercare.org)
Help us continue to provide free programs and services to anyone affected by cancer. (cancercare.org)
Patients were categorized based on malnutrition, sarcopenia, sarcopenic obesity, and advanced-lung-cancer-inflammation-index (ALI) scores after collecting nutritional and inflammatory indices. (qxmd.com)
Oral cancer is a relatively common disease worldwide and its incidence rate has increased over the years. (bvsalud.org)
Approximately 60% of the patients receive radiation therapy to treat head and neck cancer and most receive the combined therapy so that the development of a series of changes is expected to affect the oral cavity 5 . (bvsalud.org)
and within a few years, ionizing radiation was put to use on cancer patients. (endalldisease.com)
This revealed that CREB3L1 was specifically up regulated in ATC tissues and negatively associated with overall survival of patients with thyroid cancer. (biomedcentral.com)
Since 1990, the mission of MOASC is to ensure access to quality and affordable care for cancer patients. (oncologytube.com)
Socioeconomic status, access to care, risk factor patterns, and stage at diagnosis for head and neck cancer among black and white patients. (who.int)
As an awardee of the Centers for Disease Control and Prevention's Colorectal Cancer Control Program, the California Department of Public Health partnered with Neighborhood Healthcare to implement evidence-based interventions and provider incentives (incentives offered to support staff, e.g., medical assistants, phlebotomists, front office staff, lab technicians) to improve colorectal cancer screening uptake. (cdc.gov)
The purpose of this study is to evaluate the effectiveness of the West Virginia Program to Increase Colorectal Cancer Screening in implementing patient reminders to increase fecal immunochemical test (FIT) kit return rates in nine federally qualified health centers (FQHCs). (cdc.gov)

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. (uchicago.edu)

Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
Presence of lymph node involvement, ENE, and perineural invasion (PNI) were associated with inferior survival. (bvsalud.org)
Nasopharyngeal tumours cause changes in vocal timbre if they vegetate, muffled hearing, and early swelling of the cervical lymph nodes. (gsdinternational.com)
In early detected neoplasms without lymph node involvement the cure rate is between 75 and 100% of cases. (gsdinternational.com)

Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)

Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. (lookformedical.com)
This case highlights the unique clinical challenges infantile ALL poses on monitoring therapeutic response with current methods of measuring minimal residual disease as well as the challenges in treating infantile B-ALL. (authorea.com)
DESIGN/METHODS: To determine the cumulative incidence and review the clinical data of PTLD diagnosed in the cohort of pediatric patients (<18 years) who had liver transplantation performed between 1 January 2001 and 31 December 2012 in the major liver transplantation centre (Queen Mary Hospital) of Hong Kong. (hku.hk)
METHODS: To learn more about sporadic ALS etiology, we recruited n=188 ALS patients from Northern New England and Ohio and matched controls 2:1 from the general population of the same regions. (cdc.gov)

Patients were treated with toripalimab until disease progression or unacceptable toxicity. (medscape.com)
The recommended toripalimab dose with cisplatin and gemcitabine is 240 mg every 3 weeks until disease progression or unacceptable toxicity for up to 24 months. (medscape.com)
Endpoints included overall survival (OS), progression-free survival (PFS) and cumulative incidences of local failure (LF) and metastatic failure (MF). (frontiersin.org)
The median progression-free survival (PFS) of the cohort was 7.5 months (95% CI, 6.5-8.5 months). (frontiersin.org)
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. (uchicago.edu)
Consistently, high expression of CREB3L1 was negatively correlated with progression - free survival in an independent cohort. (biomedcentral.com)
In 1 child who continued to decline on bevacizumab, it was later determined that the patient had disease progression, not radiation necrosis. (medscape.com)
The comparison with immune checkpoint blockade, particularly ipilimumab, has demonstrated promising data on tilt therapy's longer progression-free survival. (oncologytube.com)

Overall, 24 patients received brachytherapy boost at a median dose of 20 Gy, and 21 patients received an SRT boost at a median dose of 15 Gy. (nih.gov)
A total of 22 patients received SBRT with a median prescribed dose of 40 Gy (range of 30-50 Gy)/4 to 7 fractions. (frontiersin.org)
The median OS of all patients was 13.6 months (95% CI, 9.6-17.5 months). (frontiersin.org)
Median survival was about the same between the two arms: 210 days versus 203 days. (oncnursingnews.com)
During the median 7.6 years of follow-up, 49 patients (74%) developed transient (n=12) or permanent (n=37) hypothyroidism at a median 3.8 years of follow-up (2.9-4.6 years). (e-apem.org)

Unlike the rebound of plasma EBV DNA concentrations in the patients who had a relapse, the plasma EBV DNA concentration was persistently low or undetectable in patients with a complete clinical remission. (nih.gov)
These terms were based on clinical and pathologic characteristics of the diseases encountered. (medscape.com)
Dr. Chung is conducting clinical trials to develop less toxic but effective molecularly targeted agents which can potentially benefit this subset of HNC patients. (moffitt.org)
Such efforts have not occurred in clinical trials of NHL and thus we are left to examine case series and try to discern its value for this disease. (authorea.com)
The novel coronavirus disease 2019 (COVID-19) shows a wide spectrum of clinical presentations, severity, and fatality rates. (mdpi.com)
We aimed to investigate clinical characteristics of pediatric patients with medulloblastoma or PNET who developed thyroid dysfunction. (e-apem.org)

The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), Public Health Service, U.S. Depart- ment of Health and Human Services, Atlanta, GA 30333. (cdc.gov)

Plasma cell-free DNA (cfDNA) methylation has shown promising results in the early detection of multiple cancers recently. (biomedcentral.com)

Middle ear effusion is suggestive of nasopharyngeal extension or invasion of the tensor veli palatini muscle. (medscape.com)

Standard management of pediatric Non-Hodgkin's Lymphoma (NHL) patients have included an initial assessment of the disease at presentation to establish it's extent. (authorea.com)

All patients with previously untreated or recurrent rare HNCs were assessed by biopsy, CT and whole body FDG PET before treatment for previously untreated or recurrent rare HNCs. (e-ceo.org)

A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. (lookformedical.com)
The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. (lookformedical.com)

They note that although radiation therapy can provide some palliation in such patients, it can also result in radiation necrosis and neurologic decline. (medscape.com)

Cats with nasal disease commonly have a history of nasal discharge and sneezing, whereas cats with nasopharyngeal disease more often have stertorous respiration, and change in phonation. (vin.com)
Nasopharynx Nasopharyngeal Tonsil the a part of pharynx which lies above the taste bud and behind the nasal cavity is known as It is a group of lymphoid tissue beneath the the nasopharynx. (ehd.org)

Systematic profiling of each step of the inflammasome signaling is essential to clarify its role in the pathology of diseases. (thno.org)

Most bacterial nosocomial pneumonias occur by aspiration of bacteria colonizing the oropharynx or upper gastrointestinal tract of the patient. (cdc.gov)

Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)

Survival rates significantly differ between NPC patients according to stages of disease. (intechopen.com)
Survival Rates by Stages. (baugeschaeft-roblick.de)

Symptoms of head and neck tumours depend on anatomical disease location. (gsdinternational.com)
If the above symptoms or signs are present, the family doctor will refer the patient for a thorough examination by a specialist and possibly identify the tests that need to be carried out to make a diagnosis. (gsdinternational.com)

FAP is an autosomal dominant genetic disease which in ~70-80% of cases is due to inheritance and in ~20-30% of case is due to a germline mutation (i.e. non-familial FAP caused by an APC gene mutation that occurs in the germ cells that develop into an individual). (wikipedia.org)
The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
Individual genetic variations lead to different responses of patients to a single treatment regimen. (researchsquare.com)

Wieneke JA, Thompson LD, Heffess CS: Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients. (oncolink.org)
Variations in toxicity and response to therapy are observed among patients despite similar clinicopathologic characteristics which are attributed to single nucleotide polymorphisms (SNPs). (researchsquare.com)

SRT boost is more effective in reverting the poor prognostic influence of local persistent disease. (nih.gov)
We aimed to construct prognostic models for advanced NPC patients with stage III-IV after their first treatment with IMRT by using machine learning algorithms and to identify the most important predictors. (qxmd.com)

Advances in radiologic technology have evolved in the way the disease extent was evaluated, moving from conventional radiographs, to computerized tomography (CT) to magnetic resonance imaging (MRI) to most recently positron emission tomography (PET)[[2]](#ref-0002). (authorea.com)

Three-quarters of patients with pediatric medulloblastoma or PNET showed thyroid dysfunction, and over half had permanent thyroid dysfunction. (e-apem.org)
Thus, frequent monitoring of thyroid function is mandatory in all patients treated for medulloblastoma or PNET, especially, in very young patients and/or high-risk patients recommended for HDCT/ASCR. (e-apem.org)

Non-concomitant administration of cabozantinib with cytotoxic therapy in this population has acceptable toxicity while allowing for potential disease control. (authorea.com)
Toxicity was measured using the Common Terminology Criteria for Adverse Events (CTCAE) v2, whereas quality of life was evaluated with two patient questionnaires: EORTC QLQ30 and oesophagus module (OES-18). (oncnursingnews.com)

The growth phase of melanoma was vertical in 13 (92.9%) patients and radial phase in one (7.1%) patient. (magiran.com)
Melanoma histology was nodular in 3 patients and unspecified or unregistered in the rest. (magiran.com)
Kalbasi began by delving into the realm of tilt therapy, a longstanding approach for melanoma patients. (oncologytube.com)
Over the last decade or two, industry interest has surged, revealing response rates of 30 to 50 percent in heavily pretreated melanoma patients. (oncologytube.com)

The conversation then shifted to TCR-engineered therapy, where Kalbasi elucidated on the exciting results observed in sarcoma patients, specifically those with synovial sarcoma expressing mage a four. (oncologytube.com)

Anatomy6

Organisms2

Diseases125

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment63

Phenomena and Processes13

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Information Science6

Health Care23

Geographicals1

Carcinoma28

Radiotherapy18

Tumors13

Tumor11

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Metastasis3

Staging4

Prognosis3

Chemotherapy10

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Cancer30

Carcinomas1

Lymph4

Metastases1

Methods4

Progression8

Median5

Clinical6

Epidemiology1

Cancers1

Invasion1

Lymphoma1

Recurrent1

Outcome2

Radiation1

Nasal2

Pathology1

Colonizing the oropha1

Tissue1

Stages2

Symptoms2

Genetic3

Clinicopathologic2

Prognostic2

Extent1

Thyroid2

Toxicity2

Melanoma4

Sarcoma Patients1