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  • Malignant
  • Oncologists hypothesized that treatment of this sub-clinical disease with radiation therapy may stamp out the malignant process before it could advance to cause symptoms. (wikipedia.org)
  • poor survival
  • Specifically, we found that up-regulation of the IL17RA, IGF2BP2 and ABCC2 genes, and of genes acting in the mTOR and cytokine receptor pathways, were strongly associated with a poor survival. (springer.com)
  • Up-regulation of the IL17RA, IGF2BP2 and ABCC2 genes, and of genes acting in the mTOR and cytokine receptor pathways, appear to be associated with a poor survival. (springer.com)
  • likelihood
  • By contrast, PCI is intended as preemptive treatment in patients with no known current intracranial tumor, but with high likelihood for harboring occult microscopic disease and eventual occurrence. (wikipedia.org)
  • gene expression
  • The NKI hypothesized that breast cancer is a genetic, heterogeneous disease, where gene expression would be different in aggressive breast tumors that develop recurrences following surgery than from those that are less aggressive and do not recur or spread throughout the body. (wikipedia.org)
  • rates
  • Survival rates in the developed world are high, with between 80% and 90% of those in England and the United States alive for at least 5 years. (wikipedia.org)
  • nodular
  • The majority of bilateral tumours can be distinguished according to size and aspect of the nodules: primary pigmented nodular adrenocortical disease which can be sporadic or part of Carney complex and primary bilateral macro nodular adrenal hyperplasia. (wikipedia.org)
  • trastuzumab
  • According to secondary data introduced at the 2015 Breast Cancer Symposium, certain subsets derived even greater benefits, 2 including those with hormone receptor-positive disease and those pretreated with trastuzumab (Herceptin) sequentially. (ascopost.com)
  • clinical
  • A lymphoma vaccine uniquely tailored for each patient extends disease-free survival by 14 months, with signs of an even better response for patients with a specific biological marker, a team led by scientists at The University of Texas MD Anderson Cancer Center reported today in the online version of Journal of Clinical Oncology. (mdanderson.org)
  • Background:We aimed to evaluate survival and disease-free survival in different subtypes of interval cancers by breast density, taking into account clinical and biological characteristics. (aacrjournals.org)
  • Correlations between these genomic and transcriptomic changes and their associations with clinical and histopathological parameters were assessed with the aim to identify molecular signatures associated with disease-free survival of the CRC patients during a 10 year follow-up. (springer.com)
  • While some nasopharyngeal cancers are biologically similar to the common HNSCC, "poorly differentiated" nasopharyngeal carcinoma is lymphoepithelioma, which is distinct in its epidemiology, biology, clinical behavior, and treatment, and is treated as a separate disease by many experts. (wikipedia.org)
  • enzyme
  • We previously reported that peroxiredoxin 4 (PRDX4), a secretory-type antioxidant enzyme, can protect against the development of various diseases, including potential malignancies. (medsci.org)
  • Treatment
  • This study shows us that we can offer our high-risk patients tolerable treatment that may prolong their chances of survival. (fredhutch.org)
  • TUESDAY, Oct. 11, 2016 (HealthDay News) - The duration of disease-free survival is increased with sunitinib treatment for patients with locoregional, high-risk clear-cell renal-cell carcinoma, according to a study published online Oct. 10 in the New England Journal of Medicine . (physiciansweekly.com)
  • The relationship between PFS and OS is altered in any case in which a successive treatment may influence survival. (wikipedia.org)
  • Treatment with docetaxel increasing survival time in people with certain types of cancer. (wikipedia.org)
  • Conjunctive treatment of prednisone with docetaxel has been shown to lead to improved survival rate as well as improved quality of life and reduction of pain compared with treatments with mitoxantrone. (wikipedia.org)
  • years
  • ExteNet's primary analysis was the invasive disease-free survival for all patients treated who had completed 2 years of follow-up. (ascopost.com)
  • The cumulative relative survival rate for all age groups and histology follow-up was 60%, 52%, and 32% at 5 years, 10 years, and 20 years, respectively, with children doing better than adults. (wikipedia.org)
  • genetic
  • Children with certain hereditary diseases, such as neurofibromatosis type II (NF2), have been found to be more frequently afflicted with this class of tumors, but a firm genetic link remains to be established. (wikipedia.org)
  • transformation
  • and EBV does not appear to play a role in the transformation process of Castleman's disease to FDC sarcoma because all cases the report found associated with Castleman's disease were EBV negative. (wikipedia.org)
  • data
  • Gnant noted that this analysis was performed as a result of a recommendation from the Independent Data Monitoring Committee (IDMC) and was based on only 370 disease-free survival events. (eurekalert.org)
  • From each of the three groups, 80% of the cases (342, 283 and 238 cases of 1-, 3- and 5-year disease-free survival, respectively) were selected to provide training data for the prediction models. (plos.org)
  • extent
  • Radiological studies of the abdomen, such as CT scans and magnetic resonance imaging are useful for identifying the site of the tumor, differentiating it from other diseases, such as adrenocortical adenoma, and determining the extent of invasion of the tumor into surrounding organs and tissues. (wikipedia.org)
  • study
  • That's significant because most cancer drugs are approved on the basis of extending survival only a few months," said Larry Kwak, M.D., Ph.D., corresponding author of the study. (mdanderson.org)
  • In 1998 the largest study on the disease was a retrospective review with fifty-one patients. (wikipedia.org)
  • women
  • Approximately half of women diagnosed with Paget's disease of the breast also have a lump in the breast. (wikipedia.org)
  • metastases
  • We are delighted with the significant results seen in the PROSPER study, showing that XTANDI plus ADT delayed clinically detectable metastases compared to ADT alone in patients with non-metastatic CRPC whose only sign of underlying disease was a rapidly rising prostate-specific antigen (PSA) level. (yahoo.com)
  • resistant
  • Higher Karnofsky scores (P less than .01, Mann-Whitney U test) and less resistant disease status at transplantation (P = .04, chi 2 test) were significant when calculations were limited to complete responses. (uni-bonn.de)
  • Tuberculosis (TB) disease rates in some parts of London are as high as in Sub-Saharan Africa, and drug-resistant strains are becoming increasingly common. (medicalnewstoday.com)
  • Carbon-ion RT has shown excellent local control for X-ray resistant diseases such as recurrent rectal carcinoma, skull-base tumors, uveal melanoma, non-squamous cell carcinomas of the head and neck, and sarcomas. (biomedcentral.com)
  • survive
  • After all you can plant white pines where Frasers have died from Phytophthora root rot and they will most likely survive, even though they are also susceptible to the disease. (blogspot.co.uk)
  • cancer
  • Can you see that the bias that cancer is a disease that strikes us ignores real causes lifestyle and dietary changes that put us out of sync with our genetically adapted to environmental roots? (positivearticles.com)
  • response
  • Although senescent cells can no longer replicate, they remain metabolically active and commonly adopt an immunogenic phenotype consisting of a pro-inflammatory secretome, the up-regulation of immune ligands, a pro-survival response, promiscuous gene expression (pGE) and stain positive for senescence-associated β-galactosidase activity. (wikipedia.org)
  • months
  • progression usually occurred less than 6 months after transplantation, most often at the sites of active disease before the transplant. (uni-bonn.de)
  • children
  • Older children often tried to keep their siblings together, and survival-searching for food and shelter became their number-one priority. (wikipedia.org)
  • After Soviet occupation and orphaned by hunger and disease, these orphan children had to care for themselves. (wikipedia.org)
  • During this time, Chisholm developed his strong Marxist view that children should be raised in an "as intellectually free environment" as possible, independent of the prejudices and biases (political, moral and religious) of their parents. (wikipedia.org)
  • earlier
  • Some years, the earlier-planted wheat does best and some years the later-planted wheat does best, depending on weather conditions and disease pressure during the growing season. (ruralmessenger.com)
  • greater
  • The experimental elimination of senescent cells from transgenic progeroid mice and non-progeroid, naturally-aged mice led to greater resistance against aging-associated diseases. (wikipedia.org)
  • found
  • Procera root rot is also a common disease found on white pines growing in fields, but was not observed at this particular site. (blogspot.co.uk)
  • common
  • A contributing factor to deteriorating nutrition is high diarrheal disease morbidity, exacerbated by the lack of access to proper sanitation and the common practice of open defecation (44 percent) in Nepal. (wikipedia.org)
  • stop
  • The potential for CMR to provide a "one-stop shop" for the assessment of ischemic heart disease has long been proposed ( 5,6 ). (onlinejacc.org)
  • basis
  • An admirer of the pre-1914 Third French Republic, he wanted the Second Spanish Republic to emulate it, make secular schooling free and compulsory, and construct a non-religious basis for national culture and citizenship, part of the necessary updating and Europeanising of Spain. (wikipedia.org)
  • often
  • Many went on food-scrounging trips into neighboring Lithuania and were adopted by the rural Lithuanian farmers, who often give them food and shelter for free. (wikipedia.org)
  • health
  • He defined health for the WHO as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity. (wikipedia.org)