• The best hopes to cure malaria, Parkinson's and Alzheimer's diseases, epilepsy, obesity, infertility and a variety of birth defects all rely on current animal experiments. (spiked-online.com)
  • Mice are genetically altered to replicate conditions like cancer, Alzheimer's, diabetes, and other human diseases. (aerzte-gegen-tierversuche.de)
  • Mini brains are generated from patients suffering from Alzheimer's or Parkinson's disease, pancreatic organoids from diabetic patients, intestinal organoids from people suffering from Chron's or inflammatory bowel disease, 3D lung models are generated from smokers and COPD (chronic obstructive pulmonary disease) or asthma patients. (eceae.org)
  • There is no doubt that these models poorly reflect complex human diseases such as Alzheimer's disease, diabetes or cancer. (eceae.org)
  • Many animal models of human diseases including Alzheimer's disease or cancer are generated by genetic engineering. (eceae.org)
  • Other animal-based experiments, however, appear to have genuine utilitarian value, contributing useful information to our knowledge of Parkinson's, Alzheimer's, and several cancers. (freakonomics.com)
  • Autopsies have been critical to our current understanding of many diseases, such as diabetes and Alzheimer's disease. (uft.org)
  • In Alzheimer's disease, and other related tauopathies, the pattern of tau deposition follows a stereotypical progression between anatomically connected brain regions. (ibecbarcelona.eu)
  • The researchers unveiled the monkeys last month at a meeting in Alpbach, Austria, and say they've also bioengineered monkeys to mimic Alzheimer's disease and motor neurone disease. (gizmodo.com)
  • Recent human epidemiological and animal experimentation studies have revealed that negative conditions occurring prenatally influence the appearance of metabolic and cardiovascular diseases, some of which are in turn risk factors for Alzheimer's disease (AD). (alzheimer-europe.org)
  • Few people who live in countries where animal experiments occur know much detail about the numbers and species of animals used, the types of procedures they endure, or the pain and suffering involved ( Hadley, 2012 ), as well as the ineffectiveness of using animals as models for humans. (brill.com)
  • The use of animals in experiments at leading federally-funded labs has increased nearly 73 percent in the past 15 years, according to a new study conducted by People for the Ethical Treatment of Animals (PETA). (cbsnews.com)
  • PETA has long campaigned for a reduction in animals used experiments and there has been a shift way from using them for such things as chemical toxicity testing and medical education. (cbsnews.com)
  • Despite new research technology, evidence that animal experiments often don't faithfully translate to humans, and the fact that a growing majority of the public opposes experiments on animals, laboratories are abusing more animals than ever before," said PETA Director of Laboratory Investigations Justin Goodman, who was a co-author on the study. (cbsnews.com)
  • He and the other authors said the sharp increase in mice used in experiments that their study revealed could be driven by federal restrictions on the use of chimpanzees, dogs and cats due to growing public pressure, and the fact that mice and other smaller animals are not included in the Animal Welfare Act. (cbsnews.com)
  • They called for avoiding the use of animals in experiments when a non-animal alternative is available, increased transparency regarding animal experiments and a greater willingness to negotiate with responsible representatives of the animal rights and welfare community about problems they have concerning animals in institutions. (cbsnews.com)
  • According to an article by PETA, "experiments on animals are cruel, expensive and generally inapplicable to humans" (PETA 1). (123helpme.com)
  • This shows how not only many laboratories and companies that use animals in their experiments are wasting money and time, but also wasting countless lives of animals. (123helpme.com)
  • Consumers are fed up with animal testing, the gruesome practice of testing products with animal research for medical experiments, makeup testing, chemical testing, and more. (caringconsumer.com)
  • PETA highlights that animal testing involves subjecting animals to painful experiments in a laboratory setting . (caringconsumer.com)
  • A Red Orange Peach report claims that over 100 million animal experiments are conducted in the United States every year. (caringconsumer.com)
  • According to those numbers from the Cruelty Free International report about animal experimentation, the top ten countries amount to using 69.7 million animals for animal experiments every year. (caringconsumer.com)
  • According to the American Anti-Vivisection Society , guinea pigs are the most common research animals, representing 22% of all animal experiments. (caringconsumer.com)
  • Some scientists advocate experiments on animals while simultaneously apologising for them. (spiked-online.com)
  • At a time when animal experiments are widely criticised, it is no surprise that their defenders emphasise these experiments' clinical benefit. (spiked-online.com)
  • What are animal experiments? (aerzte-gegen-tierversuche.de)
  • It rather serves as a basis for requirements that need to be met in order to use animals in experiments. (aerzte-gegen-tierversuche.de)
  • The experiments do not serve the well-being of the animal, but aim to answer a wide variety of the researcher's scientific questions. (aerzte-gegen-tierversuche.de)
  • For what purpose are animal experiments conducted? (aerzte-gegen-tierversuche.de)
  • Basic research has accounted for more than half of all animal experiments in Germany for years. (aerzte-gegen-tierversuche.de)
  • This is due to the fact that, as proven by many scientific studies, the transferability of findings from animal experiments to humans is by no means assured. (aerzte-gegen-tierversuche.de)
  • Given the significant differences in organ function and metabolism between animals and humans, the results of such experiments do not accurately predict the toxicity for humans. (aerzte-gegen-tierversuche.de)
  • Genetically modified animals now constitute approximately 45% of all animals used in experiments. (aerzte-gegen-tierversuche.de)
  • Also, this kind of animal experiments is unnecessary. (aerzte-gegen-tierversuche.de)
  • Because the cart of experimentation has been put before the horse of knowledge, scientists routinely end up not only inadvertently harming animals, but unknowingly executing flawed experiments bound to yield inconsistent, and thus ultimately useless, results. (freakonomics.com)
  • The moral dispute for using living things in experiments and testing pivots on the idea that animals are inferior to humans because they are not as intellectual as human beings and are incapable of reasoning (Animal Experimentation 1). (freeessaycollection.com)
  • Experiments with farm animals are important because they are an integral part of agricultural innovation. (theonlinerocket.com)
  • Experiments with farm animals allow genetic enhancements, breeding animals that grow faster, produce more meat, milk, or eggs, and are more resilient to disease. (theonlinerocket.com)
  • Nutrition research is another key area where farm animal experiments are vital. (theonlinerocket.com)
  • The tie between farm animal experiments and human medicine involves interrelated advancement and discovery for accurate scientific development. (theonlinerocket.com)
  • Experiments with farm animals are important because they can help reduce agriculture's environmental impact. (theonlinerocket.com)
  • Scientific experiments with farm animals can mitigate some of these environmental challenges. (theonlinerocket.com)
  • Experiments with farm animals play a crucial role in modern agriculture and social development. (theonlinerocket.com)
  • entitled "One health: perspectives on ethical issues and evidence from animal experiments" [1], touches on a number of important points, but fails to go far enough in exploring the innovative nature of a One Health approach to a number of scientific and ethical issues related to the overlap of human and animal health. (who.int)
  • Our article focuses on One Health in relation to ethics and a pathway to generating robust evidence from animal experiments and certainly not, as seems to be understood by Dr Lederman, that One Health provides an alternative to the conventional animal experiments. (who.int)
  • Evidence: Many systematic reviews published in the Cochrane library are inconclusive and unable to provide clinical recommendations after randomized controlled trials have been undertaken based on the results of animal experiments. (who.int)
  • Animal rights and animal experiments: An interest-based approach. (altex.org)
  • The Danish 3R survey: Knowledge, attitudes and experiences with the 3Rs among researchers involved in animal experiments in Denmark. (altex.org)
  • researchers should not only avoid research and disease control and preven- evidence from animal experiments" using more animals for experiments tion methods are mutually beneficial to [1], touches on a number of important than needed, they should also aim to humans, animals and the environment. (who.int)
  • Rabinowitz P, Scotch M, Conti L. Human and animal sentinels and evidence from animal experiments. (who.int)
  • er in studies, and generating evidence in relation to ethics and a pathway to Ethics: Subjecting human volun- ethically from prospective registration generating robust evidence from animal teers to trials in the absence of adequate of animal experiments similar to regis- experiments and certainly not, as seems results generated from animal studies, tration of clinical trials in humans. (who.int)
  • Animal experiments are used for scientific purposes, mostly within research in medicine and science. (lu.se)
  • As far as possible, animal experiments are not used. (lu.se)
  • However, there are research studies in which animal experiments provide us with knowledge that we are not yet able to acquire in any other way. (lu.se)
  • Animal experiments are strictly regulated under Swedish legislation as well as EU legislation on the protection of animals. (lu.se)
  • Animal experiments are only permitted where no alternative methods are available. (lu.se)
  • In order to conduct animal experiments in Sweden, researchers must first apply for permission to an animal experiment ethical review board, which will run an ethical review of the proposed research study. (lu.se)
  • According to Cook, the earliest and most extensive series of animal experiments to understand exposure limits were those conducted by K.B. Lehmann and others under his direction at the same Hygienic Institute where Gruber had done his work with carbon monoxide. (cdc.gov)
  • Animal Experimentation Jeremy Bentham a philosopher and a utilitarian humanitarian once said, "The question is not, "Can they reason? (123helpme.com)
  • During the same time period another famous philosopher by the name of Jeremy Bentham strongly disagreed with Descartes statements on animals. (freeessaycollection.com)
  • But why is transparency in non-human animal (hereinafter referred to as animal) research desirable, or indeed vital? (brill.com)
  • Hadley (2012) argues that the public finance much animal research but do not know what impact their taxes and donations have on animals. (brill.com)
  • Furthermore, he suggests that, since "people enjoy the benefits of animal research when they consume pharmaceuticals or undergo surgical procedures that prolong or improve the quality of their lives, it seems reasonable to inform them of the costs to animals for which their consumer choices are to some extent causally responsible" ( Hadley, 2012 , p. 105). (brill.com)
  • Good governance is another reason for transparency in animal research. (brill.com)
  • concur that "more transparency will increase public confidence in the appropriate conduct and regulation of animal research and therefore help to maintain public acceptance" (2010, p. 500). (brill.com)
  • Some in the research community have supported increased transparency to improve the public's understanding of animal research and boost its acceptability. (brill.com)
  • Thus, the only way to counter the damage done to the animal research community's public image is to increase the lay community's understanding of research practices" (O'Sullivan, 2006, p. 6). (brill.com)
  • In contrast, animal advocates emphasize the importance of public debate and awareness of the reality of research animals to improve animal welfare and to work towards an end of animal experimentation. (brill.com)
  • In general, animal advocates are confident that the more the public knows about animal research, the less it will be willing to sanction it. (brill.com)
  • Most people know nothing or little about animal research. (brill.com)
  • For example, an opinion poll, commissioned by Humane Research Australia ( hra ) in 2013, found that 43% of Australians were not aware that animals are used in experimental research in Australia ( Humane Research Australia, 2016a ). (brill.com)
  • A spokesman for the National Institute of Health dismissed the study, saying the methods could not be used to quantify the numbers of animals being used in research. (cbsnews.com)
  • It is data from reports gathered every four years regarding an average daily inventory to get a snapshot of the numbers of animals in a facility at a given time," Megan Columbus, the communications director for the NIH Office of Extramural Research, told CBS News. (cbsnews.com)
  • Columbus also said the increased numbers of animals could simply be due to the fact that "research grant awards has increased over the time period reported in the paper. (cbsnews.com)
  • Thus, while the numbers of some species reported in the Animal Welfare Assurances have risen, this may reflect the overall increase in research and not that a larger proportion of the funded research involves animals," she said. (cbsnews.com)
  • PETA also alleged that individuals on testing oversight committees are often involved in animal research themselves, which creates a potential conflict of interest. (cbsnews.com)
  • In an article accompanying the study, Lisa Hara Levin of the animal welfare group Animal Care and Control of New York and William Reppy of Duke University said the study illustrated the need to reform policies related to animal research. (cbsnews.com)
  • Inviting collaboration with people having broad intellectual backgrounds could result in sensible dialogue regarding the use of animals in research," they wrote. (cbsnews.com)
  • Animal experimentation is used in order to test products and to discover new medical research. (123helpme.com)
  • Many people's lives depend on the research done on the animals. (123helpme.com)
  • The development and enhancement of medical research has been based on the testing of animals. (123helpme.com)
  • There are many questions being asked if animal research is good or not or if the benefit for us is way greater the abuse of animals. (123helpme.com)
  • Why Animal Research? (stanford.edu)
  • The use of animals in some forms of biomedical research remains essential to the discovery of the causes, diagnoses, and treatment of disease and suffering in humans and in animals. (stanford.edu)
  • Stanford shares the public's concern for laboratory research animals. (stanford.edu)
  • We take our responsibility for the ethical treatment of animals in medical research very seriously. (stanford.edu)
  • U.S. federal laws require that non-human animal research occur to show the safety and efficacy of new treatments before any human research will be allowed to be conducted. (stanford.edu)
  • Not only do we humans benefit from this research and testing, but hundreds of drugs and treatments developed for human use are now routinely used in veterinary clinics as well, helping animals live longer, healthier lives. (stanford.edu)
  • It is important to stress that 95% of all animals necessary for biomedical research in the United States are rodents - rats and mice especially bred for laboratory use - and that animals are only one part of the larger process of biomedical research. (stanford.edu)
  • Our researchers are strong supporters of animal welfare and view their work with animals in biomedical research as a privilege. (stanford.edu)
  • Researchers requesting use of animal models at Stanford must have their research proposals reviewed by a federally mandated committee that includes two independent community members. (stanford.edu)
  • We at Stanford are dedicated to refining, reducing, and replacing animals in research whenever possible, and to using alternative methods (cell and tissue cultures, computer simulations, etc.) instead of or before animal studies are ever conducted. (stanford.edu)
  • What are the benefits of using animals in research? (stanford.edu)
  • By standard, animal research involves removing animals from their natural environment. (caringconsumer.com)
  • But there's no ambiguity about the suffering that laboratory animals go through in the name of research. (caringconsumer.com)
  • As Humane Society International highlights, for example, over 12 million animals are experimented on within Europe every year, particularly for medical research. (caringconsumer.com)
  • In the sections below I've highlighted some startling statistics about the use of animals in scientific research. (caringconsumer.com)
  • Some are more regularly used in animal research than others. (caringconsumer.com)
  • Animal research is vital to the development of new medicines and therapies. (spiked-online.com)
  • However, this argument fails to defend basic scientific research and to address concerns about animal welfare. (spiked-online.com)
  • Thus the purpose of basic animal research is to understand the animal world, and can include investigations of animal behaviour as well as animal physiology - for example, the study of migratory behaviour in birds or the study of barrel structures in the rat cerebral cortex. (spiked-online.com)
  • In the public sphere, and increasingly in the academic sphere, there is a demand that the outcome of any research project involving animals be self-consciously directed towards a clinical therapy, rather than a process of scientific enquiry. (spiked-online.com)
  • If animals suffer and experience life in a similar way to us, then animal research is simply wrong, no matter what the outcome, just as non-consensual or detrimental human research would be wrong. (spiked-online.com)
  • Everyone might agree that animal research provides great benefit but disagree vehemently as to whether it is a morally sound activity. (spiked-online.com)
  • Arguments in favour of animal research must include an acknowledgement that human beings are special, but science seems quite ambivalent on this point. (spiked-online.com)
  • Crucial aspects of causes for disease in humans, such as nutrition, stress, or lack of exercise, are not taken into account in this kind of research. (aerzte-gegen-tierversuche.de)
  • This strategy allows the establishment of a revolutionary concept of disease models for experimental biomedical research. (eceae.org)
  • Instead of effectively improving human health and driving the understanding and therapy of human diseases this research strategy provides huge amounts of false positive and false negative results. (eceae.org)
  • I'm sure that if one of my children were afflicted with a life threatening disease and experimentation on monkeys had a plausible chance of finding a cure, I'd reluctantly support that research. (freakonomics.com)
  • Document epidemiological, case study, or experimental research that advances human health without dependence on animal experimentation. (uft.org)
  • This unit will aquatint students with some of the Medical Research Modernization Committee's concerns about the scientific value of animal research. (uft.org)
  • It will also suggest a variety of non-animal methodologies that could be used as alternatives to animal research. (uft.org)
  • By these means, they have been able to promote the historically inaccurate view that animal research has been vital to medical progress. (uft.org)
  • Virtually every time Medical Research Modernization Committee (MRMC) scientists and clinicians have been asked to review animal research projects, they have found significant scientific shortcomings that make the value of the research highly questionable. (uft.org)
  • An article in the New England Journal of Medicine justified animal use in cancer research on the ground that "cancer kills humans and animals alike. (uft.org)
  • The animal research debate is of major importance to public health. (uft.org)
  • Given the enormous time, effort, and money poured into animal experimentation and the meager benefits this research has yielded to date, it is reasonable to conclude that animal research is neither an efficient nor valuable research method. (uft.org)
  • The billions of dollars currently spent on animal experimentation should be redirected to more productive research methods, preventative health programs, and treatment facilities. (uft.org)
  • In addition to such traditional research methods as clinical trials, epidemiological investigations, biopsy and autopsy, some technologically advanced methods, such as CAT and PET scans, cell and tissue cultures, computer models, and computerized post-market surveillance of drugs, permit safe, direct study of human disease. (uft.org)
  • However, the politically powerful animal research establishment continues to receive the largest share of available research funds. (uft.org)
  • The scientific merits of abandoning animal research are widely accepted, and will be intelligently and vigorously defended by physician Ray Greek, M.D. (animalliberationpressoffice.org)
  • None of the supporters of animal experimentation have provided specific evidence their research will ever effectively treat human disease, nor have they previously been willing to discuss or consider the use of more modern research techniques that no longer involve killing animals. (animalliberationpressoffice.org)
  • UCLA have no one to blame but themselves and their greed, as some faculty continue to ignore modern research techniques and waste research funding on animal experimentation. (animalliberationpressoffice.org)
  • Establishment of an in vitro model for the simulation of inflammatory bowel disease with the focus on reducing animal experimentation (3R research). (uni-saarland.de)
  • Several Of the seventy or more medical-research projects conducted by the Nazi between the fall of 1939 and the spring of 1945 were conducted at Auschwitz ("Auschwitz Medical Experimentation). (cram.com)
  • These animals are increasingly being seen as viable research subjects because humans and monkeys share similar brains and bodies. (gizmodo.com)
  • Farm animals have an important role to play in the vast landscape of agricultural research because they provide primary sources of food. (theonlinerocket.com)
  • Every step of this process demands thorough research to prevent future issues and keep the animals healthy and safe. (theonlinerocket.com)
  • With their physiological similarities to humans, animals like pigs and sheep offer invaluable insights for medical research. (theonlinerocket.com)
  • Pigs share a high degree of cardiovascular and respiratory system similarities with humans, making them ideal subjects in the research of cardiovascular diseases. (theonlinerocket.com)
  • The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and welfare. (elsevier.com)
  • The text is arranged according to specific research methods rather than to organ system or disease category. (elsevier.com)
  • The chapters in the present volume deal with special techniques which have been demonstrated to be distinct, useful methods for using laboratory animals as a basic biomedical research tool. (elsevier.com)
  • The descriptions of both fundamental and well-developed techniques of animal experimentation in various research fields should be useful to graduate students and experienced scientists who must consider variations in research approaches. (elsevier.com)
  • The book is a source of information for the scientist administrator who is frequently confronted with different proposed approaches to biological research projects utilizing animals. (elsevier.com)
  • His research led to the creation of Koch's postulates, a series of four generalized principles linking specific microorganisms to specific diseases that remain today the gold standard in medical microbiology. (embs.org)
  • Zoonoses are important threats to human and animal health, and animal research has played a role in assessing risk across species. (who.int)
  • The ethical justification and scientific utility of laboratory animal experimentation are rightly criticized, necessitating efforts to enhance humane aspects of animal research as well as to address biases and difficulties in extrapolating data from animal research to humans. (who.int)
  • Approaching zoonotic and environmental risks from a One Health perspective involves considering what research and disease control and prevention methods are mutually beneficial to humans, animals and the environment. (who.int)
  • Retrospective review of anesthetic and analgesic regimens used in animal research proposals. (altex.org)
  • 2021). Reviewing the review: A pilot study of the ethical review process of animal research in Sweden. (altex.org)
  • Aspect-seeing in animal research: The absence of justice in the harm-benefit analysis. (altex.org)
  • Public attitude formation regarding animal research. (altex.org)
  • 2014). Painful dilemmas - A study of the way the public's assessment of animal research balances costs to animals against human benefits. (altex.org)
  • Animal research that respects animal rights: Extending requirements for research with humans to animals. (altex.org)
  • Animal research for Alzheimer disease: Failures of science and ethics. (altex.org)
  • 2019). Publication rates in animal research. (altex.org)
  • Public opinion on the acceptability of animal experimentation - particularly its most controversial element, i.e. brain research in primates - is influenced overwhelmingly by the magnitude of its purported value to human health. (safermedicines.org)
  • Producing treatments for distressing disorders like Parkinson's disease provides a powerful argument in defence of such controversial research. (safermedicines.org)
  • His indignation that some would deny Parkinson's patients the fruits of animal research is misplaced, if such fruits as DBS were actually harvested from research in humans, after all. (safermedicines.org)
  • Human experimentation is when human beings are used as test subjects to research scientific and medical resources. (bartleby.com)
  • One key type of research that of scientific and ethical issues related animal experimentation to humans. (who.int)
  • The American Veterinary Medical disease control and prevention is the research has played a role in assessing Association has defined One Health as use of animal collars and vaccinations risk across species. (who.int)
  • One Health supports a shared risk and humans, can provide important mane aspects of animal research as approach, wherein animals and humans alternatives to animal experimentation. (who.int)
  • well as to address biases and difficul- are considered to be generally suscepti- As such, groups concerned with animal ties in extrapolating data from animal ble to the same environmental risks and ethics would do well to further explore research to humans. (who.int)
  • The research is to be conducted according to a protocol which has been reviewed and approved by the regional animal experiment ethical review board in Malmö/Lund. (lu.se)
  • Research techniques that focus on study designs and data gathering methods in human and animal populations. (bvsalud.org)
  • The vol- describes the relationship between phenomenology and unteers for the research were six students of university, experimentation in psychology on the basis of two dis- tutors of at least one pet. (bvsalud.org)
  • The study, in the Journal of Medical Ethics, found the number of animals tested rose from 1,566,994 in 1997 to 2,705,772 in 2012 in testing by the top 25 institutional recipients of National Institute of Health grants. (cbsnews.com)
  • Many people have questions about animal testing ethics and the animal testing debate. (stanford.edu)
  • A debate about the ethics of animal experimentation will be more informed if the science is clear before-hand. (animalliberationpressoffice.org)
  • As such, groups concerned with animal ethics would do well to further explore the applications of a One Health approach: what are the ethical guideposts as we move toward a future of health care that considers the health of multiple species as well as the environment? (who.int)
  • The 3D method: A tool to analyze positions in animal and environmental ethics. (altex.org)
  • 2018). Emotions and ethical decision‐making in animal ethics committees. (altex.org)
  • When one researches about the medical ethics in human experimentation, it is difficult to disregard the harsh realities of it. (bartleby.com)
  • The gastrointestinal tract is a major route of entry for toxic environmental chemicals involved in the etiology of numerous human diseases. (umass.edu)
  • However, these models do not resemble the complexity of human diseases which are often caused or at least massively influenced by life-style, psychological and social factors. (eceae.org)
  • It's also worth pointing out that most human diseases aren't caused by a single faulty gene, so these monkeys will likely be of limited clinical relevance. (gizmodo.com)
  • Disease Agents at 41 months postinoculation (mpi) on average, and dis- ease developed in 2/12 orally infected squirrel monkeys in Nonhuman on average of 69 mpi ( 7 ). (cdc.gov)
  • monkeys were the last orally infected monkeys to be eu- thanized because of clinical disease (80 and 107 mpi), and The Study the third heterozygote was clinically normal at 108 mpi. (cdc.gov)
  • The first person to volunteer for Canavero's procedure for head transplantation was Valery Spiridonov, a Russian computer programmer who has spinal muscular atrophy, a muscle-wasting disease. (wikipedia.org)
  • Subsequent experimentation with intrasplenic transplantation did not succeed because of graft necrosis. (medscape.com)
  • Despite extensive animal experimentation, pancreatic transplantation did not become a reality until 1966, when W.D. Kelly performed the first human, whole-organ pancreatic transplantation to treat type 1 diabetes mellitus. (medscape.com)
  • The motivation for using animal sources for organ or tissue transplantation is driven by supply and demand. (medscape.com)
  • Additionally, organs from animal sources could be transplanted into patients currently excluded from the human organ transplantation list. (medscape.com)
  • the One Health approach encourages to the overlap of human and animal While agreeing with their premise, I is the use of epidemiological studies health. (who.int)
  • Animals are susceptible to many of the same health problems as humans - cancer, diabetes, heart disease, etc. (stanford.edu)
  • Countless articles have been published in the last decades claiming that cancer, diabetes or other diseases have successfully been cured in mice or other animals. (eceae.org)
  • Modulation of immune responses by dietary components in inflammatory bowel disease, celiac disease, diabetes and obesity. (frontiersin.org)
  • This knowledge can lead to better diagnosis and treatment of many diseases, such as cancer, diabetes, Parkinson's, stroke and lung diseases. (lu.se)
  • The One Health paradigm, whether applied to zoonotic disease or other health issues affecting both animals and humans, can provide important alternatives to animal experimentation. (who.int)
  • Animals are used to test new medical treatments to see if they will be effective on humans. (123helpme.com)
  • Until such a discovery, animals must continue to play a critical role in helping researchers test potential new drugs and medical treatments for effectiveness and safety, and in identifying any undesired or dangerous side effects, such as infertility, birth defects, liver damage, toxicity, or cancer-causing potential. (stanford.edu)
  • Scientists and farmers can develop new vaccines and treatments by studying diseases in farm animals, ultimately enhancing animal welfare and public health. (theonlinerocket.com)
  • I am on the affirmative side and I think that Human experimentation is important because scientists and doctors can find new and more effective treatments for diseases. (bartleby.com)
  • In their public pronouncements, then, both researchers and animal advocates consider increased transparency to be in their own best interest (O'Sullivan, 2006). (brill.com)
  • Stanford Researchers are Obligated to Ensure the Well-Being of All Animals in Their Care. (stanford.edu)
  • Stanford researchers are obligated to ensure the well-being of animals in their care, in strict adherence to the highest standards, and in accordance with federal and state laws, regulatory guidelines, and humane principles. (stanford.edu)
  • Stanford researchers have made many important human and animal life-saving discoveries through their work. (stanford.edu)
  • Animal researchers and their academic colleagues determine medical school curricula and edit scientific journals. (uft.org)
  • Yellow Fever and Human Experimentation As researchers traveled to Cuba to study the disease, United States Army researchers soon discovered the cause of Yellow Fever. (cram.com)
  • Of the twelve remaining members, one half are researchers, animal experiment technicians or animal experiment staff. (lu.se)
  • Immunoregulatory mechanisms of dietary compounds during infectious diseases. (frontiersin.org)
  • Tauopathies are a group of neurodegenerative diseases characterized by the hyperphosphorylation and deposition of tau proteins in the brain. (ibecbarcelona.eu)
  • Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. (lu.se)
  • Animals are used in medicine, veterinary science, and biology studies to teach students basic biological knowledge although a broad spectrum of pedagogically superior, animal-free teaching methods exist. (aerzte-gegen-tierversuche.de)
  • Perhaps the concern raised over the "dangers" posed to the environment by well-meaning but careless biology teachers is merely a ruse for raising the age-old drama propagated by anti-vivisectionists, who argue that alternatives to dissection, such as computer simulations and plastic models, are just as effective teaching tool as animal dissection. (the-scientist.com)
  • This is what many historians or researches call a human experimentation in which a human of course takes into an act of manipulation of the body for further understandment. (cram.com)
  • It is cruel to animals to experience this. (123helpme.com)
  • If you're not already fed up with how cruel-and potentially wasteful -animal testing is, keep reading. (caringconsumer.com)
  • After years of refusing to debate physicians and animal advocates, UCLA vivisectors are again being challenged to publicly debate, on campus and in full view of students, faculty and the press, their outdated, scientifically fraudulent, and cruel practices experimenting on non-human animals. (animalliberationpressoffice.org)
  • Animal experimentations are very harmful the the animal body and is very cruel. (cram.com)
  • Given the severity of Parkinson's symptoms, this type of animal experimentation is both cruel and unusual. (gizmodo.com)
  • The meanest animal in the world isn't as cruel as human beings can be and these labs are proof. (whitecoatwaste.org)
  • They are also obligated to continuously update their animal-care practices based on the newest information and findings in the fields of laboratory animal care and husbandry. (stanford.edu)
  • The authors also provide four proposals to improve the ability to apply data from laboratory animal experimentation to humans. (who.int)
  • Veterinary assistants and laboratory animal caretakers did not have higher likelihood of suicide. (cdc.gov)
  • The One Health paradigm, whether tific utility of laboratory animal ex- and globally, to attain optimal health for applied to zoonotic disease or other perimentation are rightly criticized, people, animals, and our environment" health issues affecting both animals necessitating efforts to enhance hu- [2]. (who.int)
  • Project Abstract/Summary Pyruvate dehydrogenase complex (PDC) deficiency (PDCD) is a rare disease of mitochondrial energy failure in which the life expectancy of affected children is severely truncated from unrelenting lactic acidosis and/or from progressive neurological and neuromuscular degeneration. (sbir.gov)
  • Perhaps one way to come to terms with this conundrum is to consider animal experimentation in more abstract terms, rather than on a case-by-case basis (with many of those "cases" being purely hypothetical). (freakonomics.com)
  • It came to De's notice only eight years later, when he happened to read an abstract of it in the Tropical Diseases Bulletin . (embs.org)
  • CC chemokine ligand 20 and its cognate receptor CCR6 in mucosal T cell immunology and inflammatory bowel disease: odd couple or axis of evil? (google.co.in)
  • The Centers for Disease Control is investigating if Dr. Barton Williams, an orthopedic doctor, died from Multisystem Inflammatory Syndrome. (healthimpactnews.com)
  • This bias persists despite extensive evidence that - like dogs, cats and primates - animals such as mice, rats and fish experience pain, stress and distress. (cbsnews.com)
  • The Animal Procedures Committee, made up of some of the key members of British science, have written that primates have 'advanced cognitive faculties [and] complex behavioural and social needs', thus conceding that primates are so like us that they might have to be treated like us. (spiked-online.com)
  • Stroke is evoked in mice by occluding a brain artery or Parkinson's disease by injecting a poison into the brain of rats or non-human primates. (eceae.org)
  • Earlier this week, UCLA primate experimenter David Jentsch announced his formation of Pro-Test UCLA, a group of faculty and administrators who intend to defend the university's ongoing practice of killing animals, including non-human primates, as they addict them to methamphetamines, PCP , and nicotine. (animalliberationpressoffice.org)
  • Some scientists believe that humans and other primates shared a common ancestor millions of years ago and that at some point human animals split off to form their own evolutionary path. (encyclopedia.com)
  • Most nonhuman primates basically had a vegetarian diet, but human primates began capturing small animals and scavenging for meat from carcasses left behind by predators such as lions. (encyclopedia.com)
  • Human strongyloidiasis is an important neglected tropical disease primarily caused by the nematode Strongyloides stercoralis, and to a lesser extent Strongyloides fuelleborni which mainly infects non-human primates. (cdc.gov)
  • A wide variety of species are used in animal testing. (caringconsumer.com)
  • Not all animal species are used equally in animal testing. (caringconsumer.com)
  • The remaining percentage of animal tests and clinical trials are split relatively evenly among the above animal species. (caringconsumer.com)
  • WIKIMEDIA, MATTHIEU GODBOUT A recent study out of Oregon State University suggested that school teachers in North America could be contributing to the invasive species problem by releasing the live animals they use as teaching tools. (the-scientist.com)
  • it entails preventing and treating disease in one species in order to indirectly prevent and treat disease in another species [3]. (who.int)
  • I use a range of approaches (including field sampling, ecological genomics, and lab experimentation) to characterise population-level diversity and to understand how diversity shapes species interactions (e.g. predation) and species responses to environmental variation. (exeter.ac.uk)
  • Humans and animals are not the same species. (whitecoatwaste.org)
  • it entails preventing proach: what are the ethical guideposts cal approach which promotes better and treating disease in one species in as we move toward a future of health collaboration between human and order to indirectly prevent and treat care that considers the health of multi- animal health professionals in order disease in another species [3]. (who.int)
  • The spread of this inefficient and inhumane practice has caused animal use to skyrocket. (cbsnews.com)
  • While animal experimentation is necessary many people believe it is wrong and inhumane. (123helpme.com)
  • Animal experimentation may be very harmful to animals and inhumane but it is the only thing right now that is helping to discover new medical advances. (123helpme.com)
  • Inhumane animal testing is travesty that should cannot continue! (whitecoatwaste.org)
  • This procedure entails significant suffering for the animals, yet it does not yield therapies that accurately address the underlying processes in humans. (aerzte-gegen-tierversuche.de)
  • On the other hand, it is possible that many promising therapies were abandoned because inaccurate animal models yielded discouraging results. (uft.org)
  • Less than 24 hours after White Coat Waste Project exposed flagrant dog abuse and transparency failures by experimentation laboratories at the McGuire Veterans Affairs Medical Center in Richmond, Virginia, the issue was on the agenda at a high-profile Congressional hearing of the committee that funds the Department of Veterans Affairs. (whitecoatwaste.org)
  • Non-human animals do not appear to suffer from mental diseases as schizophrenia. (uft.org)
  • Typical tests involve daily administration of a substance by gavage directly into the stomach of mice, rats, or other animals. (aerzte-gegen-tierversuche.de)
  • Genes that have been found to be associated with a certain disorder in human patients are knocked out or inserted into the genome of mice, rats or other animals. (eceae.org)
  • At the heart of the animal rights debate is the issue of how humans and animals should interact with each other. (encyclopedia.com)
  • The habitats and food supplies for both humans and animals began to change. (encyclopedia.com)
  • Only now, however, are we coming to realize how incredibly sensitive experimental animals are to differential experimental environments, handlers, and procedures. (freakonomics.com)
  • Hence we come to what may very well be the inherent problem of animal experimentation: because we can never predict how an inarticulate animal capable of experiencing fear or pain or distress will react to the almost incalculable and endlessly subtle stimuli of any scientific environment, we can never fully trust the experimental results. (freakonomics.com)
  • Heinrich Hermann Robert Koch (1843-1910), German physician and microbiologist, founder of modern bacteriology, identified the specific causative agents of TB, cholera, and anthrax and gave experimental support for the concept of infectious disease basing such discoveries on animal and human experimentation (Figure 1). (embs.org)
  • Claude Bernard in his book "Experimental Medicine" discusses from this point of view the relative nature of the work of a physiologist, who establishes a gastric fistula in an animal, with that of Dr. Beaumont on the stomach of Alexis St. Martin, whose fistula was produced by a point blank gun shot in the left hypochondrium. (animalresearch.info)
  • These include, but are not limited to, (1) preventing hyperacute rejection, (2) preventing acute vascular rejection, (3) facilitating immune accommodation, (4) inducing immune tolerance, (5) preventing the transmission of viruses from xenografts into humans, and (6) addressing the ethical issues surrounding animal sources for xenografts and the appropriate selection of recipients (given that xenotransplantation remains experimental). (medscape.com)
  • As I see it, one point in particular transcends specific examples of animal experimentation to suggest that we should be doing everything possible to eliminate the practice altogether-except perhaps in the most extreme cases of direct human benefit. (freakonomics.com)
  • Human experimentation has always been a highly controversial topic and practice. (bartleby.com)
  • Prompt diagnosis and treatment of malaria can prevent severe disease or death and limit ongoing transmission to local Anopheles mosquitoes and other persons. (cdc.gov)
  • Preventing mosquito bites and controlling mosquitoes at home can prevent mosquitoborne diseases, including malaria. (cdc.gov)
  • Canavero has completed studies on central pain syndrome and Parkinson's disease. (wikipedia.org)
  • Some of his descriptions have withstood the litmus test of time and are still used in today's medicine: Amongst these are the characters Frederick, Little Dorrit's uncle, who suffers from Parkinson's disease, Fat Joe after whom the Pickwick-syndrome was named, Tiny Tim who is beaten with Pott's disease, Ebenezer Scrooge, a victim of posttraumatic embitterment disorder, and Mr. Krook who dies from spontaneous human combustion. (thieme-connect.de)
  • As reported in New Scientist , a team led by Hideyuki Okano from the Keio University School of Medicine in Tokyo has used genetic engineering to create a marmoset monkey with Parkinson's disease. (gizmodo.com)
  • 4] Porcine skin has been grafted onto burn patients,[5] and pig neuronal cells have been transplanted into patients with Parkinson (Parkinson's) disease and Huntington (Huntington's) disease. (medscape.com)
  • Parkinson's disease (PD) affects approximately 1% of people over the age of 60. (lu.se)
  • A public consultation in the United Kingdom-to which animal activists and scientists were not invited-found public support for openness and interest in a wide range of key information (Ipsos MORI, 2013). (brill.com)
  • The use of mice "reflects scientists' and laypersons' greater moral concern for animals in laboratories who are typical viewed as companion animals or as being human-like or having higher mental abilities," the authors wrote. (cbsnews.com)
  • PETA scientists have hosted workshops and webinars, published articles in peer-reviewed scientific journals, and organized funding and testing studies with the goal of developing strategies to replace animal use in acute systemic toxicity testing. (peta.org)
  • When you think of animal tests, you might think of a mouse or rat running around a maze with curious scientists looking on. (caringconsumer.com)
  • The point has to do with the fact that, as scientists use animals to further scientific knowledge, they do so without a full, or even half-full, understanding of the animals they're exploiting. (freakonomics.com)
  • Scientists who might have been rearranging animal subjects for clinical traumatization would have been unwittingly already traumatizing their subjects, thereby screwing up the results and rendering the entire experiment, not to mention the harsh treatment of the rodents, totally pointless. (freakonomics.com)
  • MRMC scientists have been particularly critical of animal models of mental illness and addiction. (uft.org)
  • The byline ("We… put the scientists' rationale to the test") claims to examine critically the scientific case for animal testing. (safermedicines.org)
  • In fact, scientific journals are replete with scientists lamenting the failings of animal tests and the disastrous consequences for human health. (safermedicines.org)
  • There is an equally important 3rd dimension: that of scientists whose concern is that patients are endangered by an unwarranted faith in animal tests which frequently prove misleading when applied to humans. (safermedicines.org)
  • Scientists can start with hypotheses and test them on animals,but without human testing they will never know if the end results will actually make real human patients feel better. (bartleby.com)
  • Some scientists believe that humans were in awe of the wild and fierce animals that they hunted. (encyclopedia.com)
  • Scientists believe that mammoths and many other large animals were driven to extinction around 10,000 BC because of climate changes, over-hunting by humans, or both. (encyclopedia.com)
  • Many so-called "animal models" try to mimic a certain aspect or symptom of a human disease by artificially harming animals. (eceae.org)
  • The basic problem is that animal models show fundamental anatomical, physiological, and pathological differences from the human disease they are said to mimic. (uft.org)
  • We conclude by recognising that although protozoa may in some cases not completely mimic tissue- or whole-animal-level processes, they are extremely flexible and their use should be embraced. (exeter.ac.uk)
  • Several medical historians have found that most major advances in areas such as heart disease and cancer have developed from human clinical investigation. (uft.org)
  • One Health is a comparative clinical approach which promotes better collaboration between human and animal health professionals in order to reduce the spread of zoonotic diseases. (who.int)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Prior to the coronavirus disease-2019 pandemic, annually reported cases were increasing in the USA, leading the US Centers for Disease Control and Prevention to develop a genotyping tool to complement cyclosporiasis outbreak investigations. (cdc.gov)
  • The study estimated that 17 million to 100 million animals are still used in laboratories. (cbsnews.com)
  • Shut down Doggy experimentation & laboratories. (whitecoatwaste.org)
  • If scientist did not experiment with animals many more people would lose their life (Derbyshire). (123helpme.com)
  • People are making an effort to save as many animals as possible when trying to experiment. (123helpme.com)
  • The implications of this sensitivity have radical implications for every experiment done on an animal. (freakonomics.com)
  • When a physiologist first made a gastric fistula in an animal to see whether it produced a normal secretion and whether an animal so operated on could exist in a healthy condition, he was making an experiment. (animalresearch.info)
  • Throughout history, animal testing has played an important role in leading to new discoveries and human benefit. (123helpme.com)
  • The study accused the federally-funded labs of breeding mice to carry genes that "predispose them to crippling diseases and other maladies. (cbsnews.com)
  • Acute tamoxifen administration in Cx3cr1-CreER mice also labels circulating monocytes, which can infiltrate the CNS in the context of injury or disease, thus complicating interpretation. (elifesciences.org)
  • Logically speaking, human genetic experimentation should be allowed. (cram.com)
  • and the Cruelty to Animals Act which was passed in 1876 (Franklin). (123helpme.com)
  • Charles Dickens loved animals, and he was a member and supporter of The Royal Society for the Protection of Cruelty to Animals and actively engaged in public activities against vivisection. (thieme-connect.de)
  • I Paige disagree with human experimentation and feel we need To stop the human cruelty. (cram.com)
  • The findings of the experimentation indicate that there may be no simple relationship between spontaneous activity and tinnitus at the level of the auditory nerve. (cdc.gov)
  • Ideally, this would replace poorly informed debate, minimize invective and balance the world's drive for scientific advance with the need to ensure animal protections. (cbsnews.com)
  • If animals are not well-treated, the science and knowledge they produce is not trustworthy and cannot be replicated, an important hallmark of the scientific method . (stanford.edu)
  • Though the average consumer may be vaguely aware of scientific or commercial testing on animals, as you read in the previous section, the realities are far worse than they can probably imagine. (caringconsumer.com)
  • Animals are used to address even the most devious scientific inquiries, driven more by a sense of tradition than by any meaningfulness. (aerzte-gegen-tierversuche.de)
  • In the recent past, scientific experts from academia and industry have increasingly criticized animal-based disease models. (eceae.org)
  • Billions upon billions of animals are used every year for the purposes of scientific experimentation. (freakonomics.com)
  • Contacted at Americans For Medical Advancement, Dr. Ray Greek, an anesthesiologist and outspoken critic of animal experimentation solely on the grounds of its scientific inefficacy, states "I am more than willing to participate in a debate on the science behind using animals to predict human response to disease and drugs. (animalliberationpressoffice.org)
  • North American Animal Liberation Press Officer Jerry Vlasak, MD, also a physician, is willing to debate UCLA animal experimenters at a separate event: "I relish the opportunity to debate not only the lack of scientific merit to animal experimentation, but I am also looking forward to explaining and defending the tactics used to stop animal abusers at UCLA. (animalliberationpressoffice.org)
  • The Sunday Times Magazine does its readers a grave disservice by publishing such a one-sided and factually incorrect article as "How would you feel if you were an animal caged for scientific testing? (safermedicines.org)
  • The hand-wringing focus on the ethical 'agonising dilemmas' is the time-honoured ploy of lobbyists for animal testing to divert attention from their untenable scientific position. (safermedicines.org)
  • 243 MPs and 83% of GPs agree and have called for a scientific evaluation of animal tests for drug safety, which currently contribute to the hospitalisation of a million Britons a year and the deaths of many thousands (see www.SaferMedicines.org ). (safermedicines.org)
  • It is abundantly clear that all of the scientific information on which the article was based came from a pro-animal testing source. (safermedicines.org)
  • Secrecy encourages infiltration and exposure by animal rights groups, while stretching the medical claim opens up a gap between the reality and rhetoric of science. (spiked-online.com)
  • The first group of six animals was tested daily and at 40 days after exposure. (cdc.gov)
  • While agreeing with their premise, I would disagree with the conclusion and would argue that the authors fail to adequately describe how the One Health approach provides alternatives to traditional use of animal experimentation. (who.int)
  • As the name implies, animal testing involves carrying out tests on animals. (caringconsumer.com)
  • Animal testing is the use of animals in biological, medical, and psychological studies. (123helpme.com)
  • With a shorter life cycle than humans, animal models can be studied throughout their whole life span and across several generations, a critical element in understanding how a disease processes and how it interacts with a whole, living biological system. (stanford.edu)
  • How does the totality of exposures that a person experiences combined with the associated biological response, relate to health and disease? (universityworldnews.com)
  • Methods of Animal Experimentation, Volume II, provides information on the most common methods for using animals as tools in the search for new biological knowledge. (elsevier.com)
  • Animal models are increasingly used to understand disease mechanisms and to screen promising therapeutic approaches. (sbir.gov)
  • The development of artificial arteries, understanding the ageing process and reversing spinal-cord injury are all being investigated using animal models. (spiked-online.com)
  • This encompasses animal testing for drug development, where animals serve as "disease models. (aerzte-gegen-tierversuche.de)
  • Such models give valuable insights into the real disease and enable the reliable investigation of the underlying molecular mechanisms and the effective development of therapeutic approaches. (eceae.org)
  • How can the co-creation, application and valorisation of in vitro models using beyond state-of-the-art technologies be improved leading to the reduction of animal experimentation? (universityworldnews.com)
  • The focus will be on human health and biomedical applications using computational models, animal models or human experimentation. (frontiersin.org)
  • However, and poor choice of animal models in standardization of procedures in animal he disagrees with our conclusion. (who.int)
  • These lessons were part of their traditional knowledge, which was grounded in cultural values and practices and refined through generations of observation, experimentation, and adaptation. (cdc.gov)
  • NaturalNews) The link between breast cancer and obesity has strengthened with two new studies showing that body mass index is correlated with the disease. (naturalnews.com)
  • Because of the specificity and robustness of microglial recombination with P2ry12-CreER , we believe that this new mouse line will be particularly useful for future studies of microglial function in development and disease. (elifesciences.org)
  • Extent and characteristics of published and non-published animal studies followed up at two German university medical centres. (altex.org)
  • equately describe how the One Health and cohort studies to assess correlation approach provides alternatives to tra- between environmental exposures and · Zoonoses are important threats to ditional use of animal experimentation. (who.int)