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  • nucleoside
  • For example, the antiherpetic drug ( E )-5-(2-bromovinyl)-dUrd (BVDU) [ 7 ] is not metabolised by the type 2 TKs (i.e. cytosolic TK) in contrast to the type 1 TKs (i.e. mitochondrial TK, HSV-1 TK) which can phosphorylate a variety of (5-substituted) nucleoside analogues including BVDU. (biomedcentral.com)
  • Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. (abcam.com)
  • 2019
  • 2019. The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein-protein interaction . (cardiff.ac.uk)