• The cause for hemispheric disconnection is if the interhemispheric fibers, as mentioned earlier, are cut or reduced. (wikipedia.org)
  • Hemispheric disconnection has impacted behaviors relating to the sensory and motor systems. (wikipedia.org)
  • In addition to hemispheric disconnection syndrome, various cognitive impairments, including dementia, occur, but the mechanism underlying them remains undetermined. (ajnr.org)
  • Certain individuals with alcohol-related dementia present with damage to the frontal lobes of their brain causing disinhibition, loss of planning and executive functions, and a disregard for the consequences of their behavior. (lumenlearning.com)
  • Glucose metabolic images obtained by [ 18 F]-2-fluoro-2-deoxy-D-glucose positron emission tomography showed diffusely reduced whole brain metabolism and strongly decreased metabolism in the frontal and parietal lobes, orbital gyrus, and thalamus. (ajnr.org)
  • The white matter lesions in the frontal lobes do not seem to influence the frontal CMRglc, because the frontal CMRglc is affected as severely as the parietal CMRglc. (ajnr.org)
  • 2:00 - 2:20 pm EST Frontal lobes and large-scale networks (Central Executive, Default Mode, and others). (lninstitute.org)
  • 3:00 - 3:20 pm EST Regulation of emotions: frontal lobes and amygdala. (lninstitute.org)
  • According to the so-called disconnection hypothesis, the loss of synaptic inputs from the medial temporal lobes (MTL) in Alzheimer's disease (AD) may lead to reduced activity of target neurons in cortical areas and, consequently, to decreased cerebral blood flow (CBF) in those areas. (uc3m.es)
  • Seventeen school-age children and 15 adults completed a reach to cleanup task while we obtained cortical activation data from bilateral inferior frontal gyrus (IFG), superior temporal sulcus (STS), and inferior parietal lobes (IPL). (frontiersin.org)
  • But the case of Phineas Gage demonstrated that language depends on the activity in different brain regions rather than one single area in frontal or temporal lobes. (hse.ru)
  • For example, although the occipital lobe is essential to visual processing, parts of the parietal, temporal, and frontal lobes on both sides also process complex visual stimuli. (msdmanuals.com)
  • Heteromodal association areas in the frontal, temporal, and parietal lobes integrate sensory data, motor feedback, and other information with instinctual and acquired memories. (msdmanuals.com)
  • The frontal lobes are anterior to the central sulcus. (msdmanuals.com)
  • Disconnection syndrome is a general term for a collection of neurological symptoms caused - via lesions to associational or commissural nerve fibres - by damage to the white matter axons of communication pathways in the cerebrum (not to be confused with the cerebellum), independent of any lesions to the cortex. (wikipedia.org)
  • Recent investigations of the rat posterior parietal cortex (PPC) suggest that this region plays a central role in action control together with the frontal cortical areas. (frontiersin.org)
  • Neuropathological findings confirmed previous indications of orbital and medial prefrontal cortex (OMPFC) damage or disconnection. (globethics.net)
  • The frontal lobe has the motor cortex divided into two regions: the primary motor area located posterior to the precentral sulcus and non-primary motor areas, including the premotor cortex, supplementary motor area, and cingulate motor areas. (nih.gov)
  • These observations are consistent with long-range functional connectivity in the cortex being broadly compromised in this disorder, although there is evidence that connections with frontal and temporal cortices may be especially vulnerable (see Geschwind and Levitt 2007 for review). (biomedcentral.com)
  • A. Easton, A. Parker, D. Gaffan, Memory Encoding and Retrieval: The Nature of the Interactions between the Primate Frontal Lobe and Posterior Cortex. (routledge.com)
  • A significant bilateral reduction in metabolism in a number of interconnected cerebral regions (hippocampal formation, thalamus, cingulate gyrus, and frontal basal cortex) was found in the amnesic patients in comparison with normal controls. (unimib.it)
  • The medial frontal cortex (sometimes called the medial prefrontal area) is important in arousal and motivation. (msdmanuals.com)
  • If lesions in this area are large and extend to the most anterior part of the cortex (frontal pole), patients sometimes become abulic (apathetic, inattentive, and markedly slow to respond). (msdmanuals.com)
  • Disconnection syndromes usually reflect circumstances where regions A and B still have their functional specializations except in domains that depend on the interconnections between the two regions. (wikipedia.org)
  • Many studies have shown that disconnection syndromes such as aphasia, agnosia, apraxia, pure alexia and many others are not caused by direct damage to functional neocortical regions. (wikipedia.org)
  • Our results thus indicate that the connections of PPC with frontal cortices are organized in a topographical fashion, supporting functional heterogeneity within PPC and frontal cortices. (frontiersin.org)
  • This finding was conceptualised as a disinhibition of emotional memory associations, most likely caused by damage or functional disconnection of the OMPFC from adjacent limbic structures. (globethics.net)
  • It is located posterior to the frontal lobe and superior to the temporal lobe and classified into two functional regions. (nih.gov)
  • Non-activated partial coherence acts as an indicator of the degree of functional disconnection between brain regions in AD. (hw.ac.uk)
  • Thus, amnesia could be due to a functional disconnection between components of this or other neural structures involved in long-term learning and retention. (unimib.it)
  • Other types of disconnection syndrome include conduction aphasia (lesion of the association tract connecting Broca's area and Wernicke's), agnosia, apraxia, pure alexia, etc. (wikipedia.org)
  • In particular, a deep right frontal lesion could disrupt connections between the limbic region and frontal lobe, which affects familiarity of self, people and places. (ysjournal.com)
  • The second section describes electrophysiological and lesion research in monkeys, where lesion and disconnection studies are rapidly adding to our knowledge of both information processing and modulatory aspects of memory formation. (routledge.com)
  • Callosal disconnection syndrome is characterized by left ideomotor apraxia and left-hand agraphia and/or tactile anomia, and is relatively rare. (wikipedia.org)
  • Signs of callosal disconnection were not noted, and aphasia, apraxia, and agnosia were not evident. (ajnr.org)
  • We report the findings of 18F-fluorodeoxyglocese positron emission tomography (FDG-PET) and diffusion tensor tractography (DTT) in a right-handed patient presenting with callosal disconnection syndrome, including alien hand syndrome, after an anterior communicating artery aneurysmal rupture. (koreamed.org)
  • Based on findings of FDG-PET and DTT, the callosal disconnection syndrome presented in the patient could be the result of loss of transcallosal inhibition in the contralateral hemisphere. (koreamed.org)
  • Callosal disconnection syndrome in a patient with corpus callosum hemorrhage: a diffusion tensor tractography study. (koreamed.org)
  • Another area of disconnection involves the occipital-temporal region, also known as Brodmann area 37, which is activated by reading in all languages. (ussromantics.com)
  • Normally, strong, automatic connections are created between this posterior region and frontal regions in the left hemisphere, but dyslexic people make connections between the left occipital-temporal area and the right-hemisphere frontal areas. (ussromantics.com)
  • In ongoing studies of the neural of typical reading, the research group at Georgetown University [a private research university in Washington DC] found that over time there is 'progressive disengagement' of the right hemisphere's larger visual recognition system in reading words, and an increasing engagement of left hemisphere's frontal, temporal, and occipital-temporal regions. (ussromantics.com)
  • Transection of the fat pad or the fascias parallel to the superior temporal line should be avoided, as the route of the frontalis nerve, again is essentially parallel to the direction of the frontal process of zygoma. (neurosurgicalatlas.com)
  • There was also no response to language in the intact left frontal lobe suggesting that the existence of language areas in the left temporal lobe is a prerequisite for the development of language areas in the left frontal lobe. (hse.ru)
  • Callosal syndrome, or split-brain, is an example of a disconnection syndrome from damage to the corpus callosum between the two hemispheres of the brain. (wikipedia.org)
  • Disconnection syndrome can also lead to aphasia, left-sided apraxia, and tactile aphasia, among other symptoms. (wikipedia.org)
  • Movement - Apraxia and agraphia may occur where responding to any verbal instructions by movement or writing in the left hand is inhibited because the left hand cannot receive these instructions from the right hemisphere, The concept of disconnection syndrome emerged in the late nineteenth century when scientists became aware that certain neurological disorders result from communication problems among brain areas. (wikipedia.org)
  • 1:20 - 1:40 pm EST Executive dysfunction in traumatic brain injury (reticulo-frontal disconnection syndrome). (lninstitute.org)
  • The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome. (koreamed.org)
  • The frontal lobe has an area called Broca's area located in the posterior inferior frontal gyrus involved in speech production. (nih.gov)
  • Posterior parietal-frontal cortical connections have been described in rats, but little is known about whether these connections are topographically organized as in the primate. (frontiersin.org)
  • Here, we injected retrograde and anterograde tracers into subdivisions of PPC as well as the frontal midline and orbital cortical areas to explore possible topographies within their connections. (frontiersin.org)
  • We found that PPC projects to several frontal cortical areas, largely reciprocating the densest input received from the same areas. (frontiersin.org)
  • Symptoms of interhemispheric disconnection after acquired brain injury are unusual in the current clini- cal practice. (bvsalud.org)
  • This work presents a case report of a 33 year old patient who developed symptoms of interhemispheric disconnection and executive function defi cits after surgery for removal of a tumor in the pituitary region, as well as the evaluation of the applicability of the neuropsychological rehabilitation program for the cognitive com- plaints presented. (bvsalud.org)
  • On axial T2-weighted images, the deep frontal white matter, including the forceps minor and a part of the centrum semiovale, was hyperintense, as was the corpus callosum ( Fig 1B ). (ajnr.org)
  • B, Axial T2-weighted MR images show a hyperintense area in the corpus callosum, periventricular hyperintensity, and hyperintense areas in the frontal white matter. (ajnr.org)
  • Our findings, therefore, corroborate the hypothesis that cognitive impairment in PSP may result from both "intrinsic" and "extrinsic" frontal lobe dysfunction, likely related to cerebellar disconnection. (maastrichtuniversity.nl)
  • Patients with orbital frontal lesions can become emotionally labile, indifferent to the implications of their actions, or both. (msdmanuals.com)
  • The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. (cdc.gov)
  • Whole-brain cerebral metabolic rate of glucose (CMRglc) is reduced diffusely and strongly in the frontal and parietal lobe and the thalamus. (ajnr.org)
  • Another showed a marked decrease of glucose metabolism in the frontal and temporo-parieto-occipital association cortices (5) , and a single-photon emission CT (SPECT) study showed a hypoperfusion in the frontoparietal region, including the primary sensorimotor strip (3) . (ajnr.org)
  • The aim of this study was to assess whether hypoperfusion in parietotemporal and frontal cortices of patients with mild cognitive impairment who converted to AD (MCI-c) and patients with mild AD is associated with atrophy in the MTL and/or microstructural changes in the white matter (WM) tracts connecting these areas. (uc3m.es)
  • Voxel-based morphometry revealed that GM pathology in TLE extends beyond the hippocampus involving other limbic areas such as the cingulum and the thalamus, as well as extralimbic areas, particularly the frontal lobe. (ox.ac.uk)
  • Our findings indicate that the elevated cortisol levels in the MDD group may injure the white matter integrity in the frontal-subcortical and frontal-limbic circuits. (cambridge.org)
  • Without intimate nurturance the limbic system is neurologically starved and does not receive the signals required for building social responses nor the frontal brain stimulation that develops bonding. (mebschooloftransformation.com)
  • Confabulating patients were compared with frontal and amnesic non-confabulating patients, as well as with neurologically healthy controls. (globethics.net)
  • He is known among neuroscientists because of his improbable survival when, due to an accident, an iron rod went from his skull and destroyed a big part of his brain's left frontal lobe [1] . (hse.ru)
  • These disorders have a key neurological commonality: disconnections in neural circuits that directly influence perception of self, which induces feelings of depersonalization. (ysjournal.com)
  • Both the garden and the barbecue area complement this wonderful house, providing comfort and disconnection zones with wonderful frontal views of the sea. (casadelmar-estates.net)
  • This pattern of structural changes is suggestive of disconnection involving preferentially frontolimbic pathways in patients with pharmacologically intractable TLE. (ox.ac.uk)
  • In fact, I use this craniotomy for high ridding parasellar and other interpeduncular lesions where significant frontal retraction may be necessary to reach the superior pole of the tumor via the standard pterional craniotomy. (neurosurgicalatlas.com)
  • As the investigation goes on, and Stone is the only one unable to speak the language, his disconnection starts to take on surreal proportions that bear resemblances to the work of David Lynch - Three Kingdoms has a lot of the Twin Peaks about it, and the excellent Tennant sustains an increasingly frantic, desperate performance. (blogspot.com)
  • During the past centuries, several researchers have described that there are personality changes that occurred after frontal lobe injuries. (nih.gov)
  • Los síntomas de desconexión interhemisférica después de una lesión cerebral adquirida son inusuales en la práctica clínica actual. (bvsalud.org)
  • This primary disconnection from the Source then attracts situations that reflect that disconnection and create more suffering. (exopoliticsindia.in)
  • This implant is positioned in the frontal lobe of the brain on the plasma and etheric plane, is filled with charged rotating anomalous plasma and has the primary message that we are separated from the Source / Love / Light. (exopoliticsindia.in)
  • Being wrong might lead to relational disconnection. (westbrook.cc)
  • 1:00 - 1:20 pm EST Executive functions and frontal-lobe functions: are they the same? (lninstitute.org)