- Dobutamine stress echocardiography, myocardial perfusion scintigraphy and dipyridamole stress testing can be used to detect coronary disease in these patients. (bvsalud.org)
- Left ventricular hypertrophy and left ventricular dysfunction can be detected and monitored using various techniques with differing complexity and cost, including ECG, echocardiography, nuclear magnetic resonance, CT and myocardial scintigraphy. (bvsalud.org)
- Clinicians should not screen asymptomatic, low-risk adults for cardiac disease using resting or stress electrocardiography, stress echocardiography, or stress myocardial perfusion imaging. (medscape.com)
- Dobutamine stress echocardiography is feasible in anesthetized patients with severe coronary artery disease. (silverchair.com)
- The lack of serious complications and the high sensitivity to detect inducible ischemia in this patient population provide the basis for further evaluation of the safety and diagnostic value of dobutamine stress echocardiography during general anesthesia in larger studies of patients at risk for coronary artery disease undergoing noncardiac surgery. (silverchair.com)
- These guidelines conclude that nuclear cardiology and stress echocardiography provide comparable information on diagnosis accuracy for noninvasive detection of coronary disease, identification of myocardial viability and prognostic stratification. (escardio.org)
- The sensitivity, specificity and accuracy of fast (or atropine-potentiated) high-dose dipyridamole is identical to dobutamine stress echocardiography, as shown by this meta-analysis including five studies with 435 patients. (escardio.org)
- Wall motion (WM), Doppler-derived measurement of the coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD), and myocardial perfusion imaging (MPI) can be sequentially assessed during dipyridamole stress echocardiography. (thoracickey.com)
- Dipyridamole stress echocardiography was performed in 400 patients at two centers, before the performance of clinically indicated coronary angiography. (thoracickey.com)
- 50% during dipyridamole stress echocardiography, despite showing the lowest specificity among tested parameters. (thoracickey.com)
- During the past decade, stress echocardiography (SE) has moved beyond the standalone analysis of wall motion (WM), thanks to the clinical feasibility of both Doppler-derived measurement of coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD) and contrast myocardial perfusion imaging (MPI). (thoracickey.com)
- Dipyridamole is the ideal stressor for the sequential assessment of WM, CFR-LAD, and MPI within the same examination, because each of the 3 parameters has largely proven its diagnostic value for CAD detection using high-dose dipyridamole stress echocardiography. (thoracickey.com)
- Study objectives: Dobutamine echocardiography is widely used for the evaluation of myocardial contractile reserve. (the-medical-dictionary.com)
- Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with technetium-99m ( 99m Tc)-labelled radiotracers. (cadth.ca)
- A myocardial perfusion SPECT (single photon emission computed tomography) test is a procedure that demonstrates the function of the myocardium. (medscape.com)
- In a recent study published in Scientific Reports , researchers investigated the performance of a machine learning (ML)-based model in evaluating radiomic features to diagnose coronary artery disease (CAD) and its susceptibility using myocardial perfusion imaging (MPI) single-photon emission computed tomography (SPECT) images. (news-medical.net)
- 7,8 Through sequential image acquisition, the gamma camera works with a computer to evaluate cardiac function and perfusion. (cadth.ca)
- Biomarkers of myocardial ischaemia, such as troponins and electrocardiography (ECG), have limited utility for diagnosing cardiac ischaemia in patients with advanced CKD. (bvsalud.org)
- A heart perfusion imaging scan can also evaluate the effectiveness of certain cardiac treatments, such as coronary artery stenting or bypass surgery . (medicalnewstoday.com)
- Dobutamine increases myocardial contractility by stimulating beta-1 adrenergic receptors in the heart, and causes vasodilation by stimulating beta-2 adrenergic receptors in blood vessels, complemented by reflex vasoconstriction to the increase cardiac output. (the-medical-dictionary.com)
- 1 The basic principle of radionuclide MPI is to administer a radiopharmaceutical intravenously and image blood flow to the heart muscle (myocardial perfusion), both at rest and under stress. (cadth.ca)
- In 36 patients with low-flow, low-gradient AS, dynamic [ 13 N]ammonia PET perfusion imaging was performed at rest (n = 36) and during dipyridamole stress (n = 20) to quantify MBF and MFR. (bmj.com)
- Stress was induced by dobutamine, dipyridamole, and exercise. (news-medical.net)
- Prognostic value of treadmill exercise and dobutamine stress positron emission tomography. (ionetix.com)
- Treadmill exercise produces larger perfusion defects than dipyridamole stress N-13 ammonia positron emission tomography. (ionetix.com)
- N-13 Ammonia Injection is a radioactive diagnostic agent for Positron Emission Tomography (PET) indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease. (ionetix.com)
- If a person experiences chest pain , especially during physical activity or times of stress, doctors may recommend a heart perfusion imaging scan to understand the reason for the pain. (medicalnewstoday.com)
- Patients with an inconclusive test result and patients who are incapable of performing a satisfactory treadmill exercise test have to be further assessed by specific noninvasive diagnostic tests, such as Thallium-201 perfusion scintigraphy, pharmacological stress echocardiography or single photon emission computed tomography to select those patients with a high probability of disease, where coronary angiography is reasonable and cost-effective 5 . (ersjournals.com)
- A standard dobutamine-atropine stress protocol was performed in 80 patients with severe coronary artery disease during fentanyl-isoflurane anesthesia. (silverchair.com)
- Consider 2 other nuclear stress test agents - intravenous dipyridamole , which is FDA-approved for this use, and dobutamine , which is not FDA-approved. (medscape.com)
- The FDA placed regadenoson on its quarterly list of drugs to monitor in September after it received reports possibly linking the drug to myocardial infarctions (MI) and death during the second quarter of 2013 through its FDA Adverse Event Reporting System (FAERS) database. (medscape.com)
- These disorders can also decrease relative myocardial perfusion because myocardial mass is increased (causing decreased diastolic flow). (msdmanuals.com)
- In some patients, myocardial ischaemia produces a significant transient decrease in the diastolic or systolic function of the ventricle that is responsible for exertional dyspnoea. (ersjournals.com)
- The most widely used test to obtain objective evidence of myocardial ischaemia is treadmill exercise testing with a sensitivity of 60-70% and a specificity of ∼80% 4 . (ersjournals.com)
- 7 Viable myocardial cells take up the radionuclide tracer (either thallium isotope [ 201 TI] or isotope 99m Tc-labelled radiotracer) in proportion to blood flow. (cadth.ca)
- Angina pectoris (literally, "strangling" in the chest) is a syndrome of recurrent discomfort in the chest or related areas associated with myocardial ischaemia or dysfunction but without myocardial necrosis 1 . (ersjournals.com)
- Myocardial blood flow in patients with low-flow, low-gradient aortic stenosis: differences between true and pseudo-severe aortic stenosis. (bmj.com)
- Impairment of myocardial flow reserve (MFR) in aortic stenosis (AS) with normal left ventricular function relates to the haemodynamic severity. (bmj.com)
- Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)
- Ultimately, only a coronary blood flow is increased due to a simultaneous increase fraction of angina patients is treated with revascularization (5- in coronary perfusion pressure and a decrease in coronary 7). (readkong.com)
- 1. Aggarwal NR, Drozdova A, Askew JW, Kemp BJ, Chareonthaitawee P. Feasibility and diagnostic accuracy of exercise treadmill nitrogen-N-13 Ammonia PET myocardial perfusion imaging of obese patients. (ionetix.com)
- We sought to prospectively compare the diagnostic value of combined WM, CFR-LAD, and MPI assessment during dipyridamole SE in patients undergoing clinically indicated coronary angiography. (thoracickey.com)
- METHODS: Twenty-five patients with untreated mild essential hypertension and normal coronary vessels and 10 control subjects underwent dipyridamole-rest Tc-99m sestamibi imaging. (cnr.it)
- CONCLUSION: Sestamibi imaging may detect impaired coronary vascular function in response to dipyridamole in patients with untreated mild essential hypertension and normal coronary arteries. (cnr.it)
- Nuclear cardiology studies employ non-invasive techniques for assessing myocardial blood flow, the heart's pumping function, and also to identify the size and location of the damaged heart tissue. (azheartdoctor.com)
- the corresponding decrease in signal intensity observed depends on the local Gd concentration, which may be considered a proxy for perfusion. (wikipedia.org)
- Perfusion is the passage of fluid through the lymphatic system or blood vessels to an organ or a tissue. (wikipedia.org)
- Perfusion measurements are taken by comparing the radioactivity of selected regions within the body to radioactivity of blood samples withdrawn at the time of microsphere injection. (wikipedia.org)
- The acquired time series data are then postprocessed to obtain perfusion maps with different parameters, such as BV (blood volume), BF (blood flow), MTT (mean transit time) and TTP (time to peak). (wikipedia.org)
- To investigate whether myocardial blood flow (MBF) and MFR differ in low-flow, low-gradient AS depending on whether there is underlying true-severe AS (TSAS) or pseudo-severe AS (PSAS). (bmj.com)
- After a heart attack , a perfusion scan can assess damage to the heart muscle and help doctors identify areas with reduced blood flow, which can guide treatment decisions and rehabilitation plans. (medicalnewstoday.com)
- Changes in myocardial blood flow in a canine model of left sided breast cancer radiotherapy. (ottawaheart.ca)
- Myocardial blood flow (MBF) was estimated by measuring first transit counts in pulmonary artery and myocardial counts from tomograhic images. (cnr.it)
- Regional myocardial function can be estimated visually in an SSFP sequence, but can be quantified more accurately using myocardial tagging techniques such as spatial modulation of magnetisation. (ecrjournal.com)
- MRI is considered the gold standard in the evaluation of myocardial function. (ecrjournal.com)
- MRI is now considered the gold standard in the evaluation of myocardial function because of its high accuracy as well as inter- and intra-observer reproducibility. (ecrjournal.com)
- Alternating LBBB and RBBB: suggests extensive myocardial injury and high risk of CHB. (abcmedicalnotes.com)
- Modelling of DCE-MRI yields parameters related to vascular permeability and extravasation transfer rate (see main article on perfusion MRI). (wikipedia.org)