• Other names in common use include galactose-1-phosphate uridylyltransferase, galactose 1-phosphate uridylyltransferase, alpha-D-galactose 1-phosphate uridylyltransferase, galactose 1-phosphate uridyltransferase, UDPgalactose pyrophosphorylase, uridine diphosphate galactose pyrophosphorylase, and uridine diphosphogalactose pyrophosphorylase. (wikipedia.org)
  • ADP-Glc pyrophosphorylase (AGPase), which catalyzes the transformation of ATP and glucose-1-phosphate (Glc-1-P) into adenosine diphosphate glucose (ADP-Glc), acts as a rate-limiting enzyme in crop starch biosynthesis. (bvsalud.org)
  • In enzymology, an UTP-hexose-1-phosphate uridylyltransferase (EC 2.7.7.10) is an enzyme that catalyzes the chemical reaction UTP + alpha-D-galactose 1-phosphate ⇌ {\displaystyle \rightleftharpoons } diphosphate + UDP-galactose Thus, the two substrates of this enzyme are UTP and alpha-D-galactose 1-phosphate, whereas its two products are diphosphate and UDP-galactose. (wikipedia.org)
  • This is followed by GlcNAc phosphomutase (PGM3/AGM1)-mediated isomerization into GlcNAc-1-phosphate (GlcNAc-1-P). Finally, UTP and GlcNAc-1Pz produce UDP-GlcNAc through UDP-N-acetylglucosamine pyrophosphorylase (UAP1/AGX1) enzyme [ 6 , 7 ]. (biomedcentral.com)
  • In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. (ecmdb.ca)
  • 12. Overexpression of human UDP-glucose pyrophosphorylase rescues galactose-1-phosphate uridyltransferase-deficient yeast. (nih.gov)
  • A quantitative galactose-1-phosphate uridyltransferase (GALT) level is used in addition to the isoelectric focusing for accurate interpretation. (mayocliniclabs.com)
  • A quantitative galactose-1-phosphate uridyltransferase level (GALT / Galactose-1-Phosphate Uridyltransferase, Blood) is required for accurate interpretation. (mayocliniclabs.com)
  • In enzymology, an UTP-hexose-1-phosphate uridylyltransferase (EC 2.7.7.10) is an enzyme that catalyzes the chemical reaction UTP + alpha-D-galactose 1-phosphate ⇌ {\displaystyle \rightleftharpoons } diphosphate + UDP-galactose Thus, the two substrates of this enzyme are UTP and alpha-D-galactose 1-phosphate, whereas its two products are diphosphate and UDP-galactose. (wikipedia.org)
  • The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. (mcw.edu)
  • This enzyme participates in galactose metabolism and nucleotide sugars metabolism. (wikipedia.org)
  • 16. Molecular basis of disorders of human galactose metabolism: past, present, and future. (nih.gov)
  • Minor amounts of UDP-glucose are used to form UDP-glucuronate and UDP-galactose, which are donors of monosaccharide units used in glycosylation. (nih.gov)
  • UDP-glucose (Figure 11.4) is synthesized from glucose 1-phosphate and UTP by UDP-glucose pyrophosphorylase (Figure 11.5). (pharmacy180.com)
  • The hydrolysis is exergonic, ensuring that the UDP-glucose pyrophosphorylase reaction proceeds in the direction of UDP-glucose production. (pharmacy180.com)
  • 20. Activity of hepatic galactose-metabolizing enzymes in the pregnant rat and fetus. (nih.gov)