• Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam species, such as the Kokoro. (wikipedia.org)
  • The leaves contain at least 7 saponins, known as graecunins, which are glycosides of diosgenin. (drugs.com)
  • These saponins include asparanin A, sarsasapogenin, protodioscin and even small quantities of diosgenin. (vitamedica.com)
  • Especially concentrated in yams, diosgenin is perhaps the most extensively studied saponins. (vitamedica.com)
  • Fenugreek contains diosgenin, a plant-based estrogen, which is thought to increase milk flow in lactating women to help support breast milk production. (fairhavenhealth.com)
  • The breast enhancing results of fenugreek compounds corresponding to diosgenin and different plant phyto-estrogens is just starting to be recognized by fashionable drugs. (pohmelya.net)
  • Diosgenin is a pure steroidal sapogenin involved in several performance enhancing pathways. (nutritionalsupplementshop.com)
  • Diosgenin is a steroidal compound so this aspect may carry over and promote retention and higher circulating levels of diosgenin. (nutritionalsupplementshop.com)
  • Diosgenin is a naturally-occurring steroidal saponin present in Solanum nigrum (Solanaceae). (ijpsr.com)
  • Diosgenin serves as important starting material for the production of corticosteroids, sexual hormones, oral contraceptives as well as other steroidal drugs. (ijpsr.com)
  • It is reported that Dioscorea bulbifera extract, which is similar to the DN extract that both are rich in diosgenin, improves vascular function by superoxide dismutase (SOD) and catalase (CAT) activity. (hindawi.com)
  • Many HPLC methods have been reported for determination of diosgenin in various species of genus Dioscorea . (ijpsr.com)
  • Wild yam root extract* (Dioscorea villosa) with 20% diosgenin, hydroxypropylmethylcellulose (capsule shell of vegetable origin). (narayana-verlag.com)
  • Diosgenin from Mexican yams (Dioscorea spp. (medscape.com)
  • Diosgenin is a precursor for several hormones, starting with the Marker degradation process, which includes synthesis of progesterone. (wikipedia.org)
  • Diosgenin, a precursor used in commercial steroid synthesis, is extracted from the seeds. (drugs.com)
  • Thus, we hypothesized that diosgenin is a bioactive metabolite related to the antimyocardial ischemia (MI) activity of DN. (hindawi.com)
  • Plant tissue cultures from seeds grown under optimal conditions have been found to produce as much as 2% diosgenin with smaller amounts of gitongenin and trigogenin. (drugs.com)
  • Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus. (planteome.org)
  • The proposed method was found to be robust in terms of % w/w of diosgenin. (ijpsr.com)
  • The developed and validated method was applied for quantitative determination of diosgenin in extracts and formulations containing Solanum nigrum . (ijpsr.com)
  • Our results demonstrate that diosgenin is the main metabolite produced by rat intestinal microflora from DN. (hindawi.com)
  • Our recent research further showed that diosgenin, as a main metabolite from DN, was found and quantified in the plasma from the experimental rat group orally receiving DN [ 8 ]. (hindawi.com)
  • Rhizomes are the main source of diosgenin. (stuartxchange.org)
  • Click the button below to add the Diosgenin 5g to your wish list. (p212121.com)
  • Further, our results show that diosgenin protects the myocardium against ischemic insult through increasing enzymatic and nonenzymatic antioxidant levels in vivo and by decreasing oxidative stress damage. (hindawi.com)
  • Research has also shown that diosgenin can increase GLUT4 in the muscle which can drive glucose from the blood stream directly into the muscles. (nutritionalsupplementshop.com)
  • Wild Yam Extrakt Kapseln von Unimedica enthalten je Kapsel 440 mg Wild Yam Extrakt, davon 20 % Diosgenin. (narayana-verlag.com)
  • The sugar-free (aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. (wikipedia.org)
  • Seeds contain 0.1% to 0.9% diosgenin and are extracted on a commercial basis. (drugs.com)
  • Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. (adooq.com)
  • 16. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. (nih.gov)
  • Diosgenin is a saponin aglycone, obtained principally from the roots of plants belonging to the genus Dioscorea (Dioscoreaceae). (progesteronetherapy.com)
  • Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam species, such as the Kokoro. (wikipedia.org)
  • Diosgenin is an isospirostane derivative, which is a steroidal sapogenin and the product of acids or enzymes hydrolysis process of dioscin and protodioscin. (springeropen.com)
  • 12. The role of diosgenin in diabetes and diabetic complications. (nih.gov)
  • Diosgenin, an extract of wild yam, is one of the most biologically active alkaloids in wild yam. (pure-plantextract.com)
  • Shows that yam extract diosgenin can prevent the spread of cancer cells. (pure-plantextract.com)
  • Diosgenin-rich yam extract enhances cognitive function: a placebo-controlled, randomized, double-blind, crossover study of healthy adults. (medlineplus.gov)
  • Each two-capsule serving of Swanson Wild Yam Root combines 190 mg of powdered root with 810 mg of standardized extract (10% diosgenin concentration) for guaranteed-potency herbal support. (swansonvitamins.com)
  • 17. Evaluation of antioxidant, anti-inflammatory and anticancer activities of diosgenin enriched Paris polyphylla rhizome extract of Indian Himalayan landraces. (nih.gov)
  • This wild yam contains a compound called Diosgenin that is the precursor to steroid hormones. (healthy.net)
  • 18. Diosgenin a steroidal compound: An emerging way to cancer management. (nih.gov)
  • During a proprietary laboratory process, the compound diosgenin is extracted from wild yam (dioscorea) which is then used to synthesize DHEA. (longnaturalhealth.com)
  • Compound called diosgenin and all pairs of the queues at local pharmacies. (me-cabo.com)
  • Diosgenin is a phytoestrogen, which means The molecule comes from plants, but it affects hormones such as estrogen and dehydroepiandrosterone (DHEA). (pure-plantextract.com)
  • Wild yam is a plant that has been promoted as natural DHEA because it contains diosgenin, which can be used in the lab to create estrogen and DHEA. (medlineplus.gov)
  • Therefore, if you swallow pills that are extracts of wild yams (Diosgenin), you will not get Preg or DHEA. (healthy.net)
  • Diosgenin stimuliert die Produktion von DHEA (einer Vorläufersubstanz des körpereigenen Sexualhormons Östrogen) in den Drüsen der Nebennieren. (yamswurzel.info)
  • Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. (medscape.com)
  • 2. Diosgenin induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. (nih.gov)
  • 10. Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells with the disruption of Ca2+ homeostasis. (nih.gov)
  • 15. Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression. (nih.gov)
  • The sugar-free (aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. (wikipedia.org)
  • Sarsaparilla inneholder 1.8-2,4 % steroide saponiner, inklusive sarsasaponin (= parillin), smilasaponin (= smilacin) og sarsaparillosid, og deres aglykoner sarsasapogenin (= parigenin), smilagenin og diosgenin. (rolv.no)
  • 4. Induction of G2/M Phase Arrest by Diosgenin via Activation of Chk1 Kinase and Cdc25C Regulatory Pathways to Promote Apoptosis in Human Breast Cancer Cells. (nih.gov)
  • 13. Novel diosgenin-amino acid-benzoic acid mustard trihybrids exert antitumor effects via cell cycle arrest and apoptosis. (nih.gov)
  • 8. Design, synthesis and biological evaluation of novel diosgenin-benzoic acid mustard hybrids with potential anti-proliferative activities in human hepatoma HepG2 cells. (nih.gov)
  • In a laboratory, Diosgenin is converted into Preg. (healthy.net)
  • The conversion of Diosgenin to Preg has to be done in a laboratory. (healthy.net)
  • 1. Diosgenin increases BBC3 expression in HepG2/C3A cells and alters cell communication in a 3D spheroid model. (nih.gov)
  • Considering the importance of diosgenin and galactomannans, the obtained findings suggest potential of diosgenin and galactomannans as natural products in pharmaceutical industries. (springeropen.com)
  • The goal of this manuscript is survey on the most important health benefits and pharmaceutical advantages of galactomannan and diosgenin with considering traditional knowledge of natural products. (springeropen.com)
  • The human body does not have the ability (the required enzymes) to convert Diosgenin into Preg. (healthy.net)