• Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. (uci.edu)
  • Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). (uci.edu)
  • FLIM-FRET analysis of protein-protein interactions showed that PLIN5 S155 phosphorylation regulates PLIN5 interaction with adipose triglyceride lipase at the lipid droplet, but not with α-β hydrolase domain-containing 5. (uci.edu)
  • The propeptide of pulmonary surfactant C has an N-terminal alpha-helical segment whose suggested function was stabilization of the protein structure, since the mature peptide can irreversibly transform from its native alpha-helical structure to beta-sheet aggregates and form amyloid fibrils. (wikipedia.org)
  • High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C". Proceedings of the National Academy of Sciences of the United States of America. (wikipedia.org)
  • Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C". The FEBS Journal. (wikipedia.org)
  • Here we describe the 3.2 Å cryo-EM structure of human DEC-205, thereby illuminating the structure of the mannose receptor protein family. (uci.edu)
  • Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein. (lookformedical.com)
  • Revised Manuscript Received March 8, I990 ABSTRACT: A low molecular weight hydrophobic protein was isolated from porcine lung lavage fluid using silicic acid and Sephadex LH-20 chromatography. (datapdf.com)
  • [ 80 , 81 ] The use of liposomes for pulmonary administration of several drugs including peptides and therapeutic proteins and DNA for gene therapy has been suggested. (medscape.com)
  • Recombinant SP-C is used in Venticute, an artificial lung surfactant. (wikipedia.org)
  • High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C". Proceedings of the National Academy of Sciences of the United States of America. (wikipedia.org)
  • Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C". The FEBS Journal. (wikipedia.org)
  • It is a membrane protein. (wikipedia.org)
  • They are also used to study membranes and membrane proteins. (lookformedical.com)
  • MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)
  • Several formulations containing nanocarriers have been developed for pulmonary delivery of insulin in order to overcome the problems associated with conventional formulations. (medscape.com)
  • Amino acid compositional analysis and sequencing data suggest that this protein preparation contains intact surfactant protein SP-C and about 30% of truncated SP-C (N-terminal leucine absent). (datapdf.com)