Diltiazem. Medical search. Frequent questions

Myocardial bridge For supraventricular tachycardias (PSVT), diltiazem appears to be as effective as verapamil in treating re-entrant supraventricular tachycardia. (wikipedia.org)
To evaluate the degree of drug-drug interaction concerning metabolic inhibition in the liver quantitatively, we tried to predict the plasma concentration increasing ratio (R) of midazolam (MDZ) by erythromycin (EM), diltiazem (DLZ), or verapamil (VER) in rats. (aspetjournals.org)
The haemodynamic effects of 4 calcium antagonists, bepridil (1.25 to 5 mg/kg i.v.), diltiazem (0.1 to 0.3 mg/kg i.v.), nifedipine (0.01 to 0.03 mg/kg i.v.) and verapamil (0.1 to 0.3 mg/kg i.v.) were compared in anaesthetized open-chest dogs. (eurekamag.com)
The most marked negative chronotropic effects were seen with diltiazem, verapamil and bepridil in that order. (eurekamag.com)
Nifedipine and verapamil produced the greatest negative inotropic effects, whereas diltiazem had very little effect on this parameter. (eurekamag.com)
Diltiazem is a non-dihydropyridine (DHP)member of the calcium channel blocker class, along with Verapamil. (illumina.com)
Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, diltiazem, like verapamil, inhibits the influx of extracellular calcium across both the myocardial and vascular smooth muscle cell membranes. (illumina.com)
clonidine moderate complete av block resulting in a nodal rhythm and sinus bradycardia resulting in hospitalization and pacemaker insertion have been reported during combination therapy of clonidine with diltiazem or verapamil. (babas.se)
the dose of lovastatin should not exceed 20 mg daily in patients receiving concomitant medication with danazol, diltiazem, dronedarone or verapamil. (larumbejoyeros.com)

Compare Diltiazem (Tiazac) prices available at Canadian and international online pharmacies with local U.S. pharmacy coupon prices. (pharmacychecker.com)

Intravenous diltiazem should be used with caution with beta-blockers because, while the combination is most potent at reducing heart rate, there are rare instances of dysrhythmia and AV node block. (wikipedia.org)
There are as yet few data on the interaction of diltiazem and beta-blockers. (nih.gov)
experience with the use of diltiazem in combination with beta-blockers in patients with impaired ventricular function is limited. (babas.se)

Ask your pharmacist if you should take diltiazem with or without food, because instructions may vary with each product. (medlineplus.gov)
Take diltiazem at around the same time(s) every day. (medlineplus.gov)
Take diltiazem exactly as directed. (medlineplus.gov)
Continue to take diltiazem even if you feel well. (medlineplus.gov)
If your physician has instructed or directed you to take Diltiazem medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. (internationaldrugmart.com)
Take diltiazem exactly as prescribed by your doctor. (2su.su)
Take diltiazem with a full glass of water. (2su.su)
The EP said it was not necessary to take diltiazem since I am in and out of afib all the time and as long as my heart rate was not high for an extended period of time. (cardiachealth.org)

The average diltiazem dosage was 16.7 mg. (medscape.com)
Diltiazem Hydrochloride Extended-Release Capsules USP (Once-a-Day Dosage) contain diltiazem hydrochloride in extended-release pellets at doses of 120, 180, 240, 300 and 360 mg. (nih.gov)
Diltiazem hydrochloride extended-release capsule, USP (Once-a-day dosage) is formulated as a once-a-day extended-release capsule containing 120 mg diltiazem hydrochloride (equivalent to 110.3 mg diltiazem), 180 mg diltiazem hydrochloride (equivalent to 165.45 mg diltiazem), 240 mg diltiazem hydrochloride (equivalent to 220.6 mg diltiazem), 300 mg diltiazem hydrochloride (equivalent to 275.75 mg diltiazem), or 360 mg diltiazem hydrochloride (equivalent to 330.9 mg diltiazem). (nih.gov)
What is the recommended dosage of Diltiazem? (internationaldrugmart.com)
The dosage of Diltiazem prescribed to each patient will vary. (internationaldrugmart.com)
Diltiazem has numerous dosage forms (IV, immediate release tablets, and extended-release products). (rosalindfranklin.edu)
The numerous dosage forms of diltiazem is a medication safety issue. (rosalindfranklin.edu)

Our goals were to determine whether the prehospital administration of diltiazem induced hypotension and to evaluate the efficacy of the drug. (medscape.com)
In the prehospital setting, diltiazem is associated with a very low rate of hypotension and appears to be effective in decreasing HR adequately. (medscape.com)
Side effects of metoprolol and diltiazem that are similar include constipation , nausea , and low blood pressure ( hypotension ). (hdkino.org)

What is Diltiazem CD 180mg Capsules used for? (internationaldrugmart.com)
What are the side effects of Diltiazem CD 180mg Capsules? (internationaldrugmart.com)
Like other medicines, Diltiazem CD 180mg Capsules can cause some side effects. (internationaldrugmart.com)
What other drugs could interact with Diltiazem CD 180mg Capsules? (internationaldrugmart.com)

We retrospectively reviewed patient care records for those who were believed to be in rapid atrial fibrillation and were given diltiazem in a suburban emergeny medical services system over a 22-month period. (medscape.com)
Many emergency medical services (EMS) systems have adopted the adult advanced cardiac life support guidelines recommending the use of intravenous (IV) diltiazem as a first-line pharmacotherapy to control the ventricular response in rapid atrial fibrillation. (medscape.com)

Alcohol also increases the rate at which some controlled and extended-release formulas of diltiazem (such as Cardizem CD) release diltiazem in vitro. (wellrx.com)

Diltiazem comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. (medlineplus.gov)
Your doctor will probably start you on a low dose of diltiazem and gradually increase your dose, not more than once every 7 to 14 days if you are taking the extended-release tablet or capsule and not more than once every 1 to 2 days if you are taking the regular tablet. (medlineplus.gov)
If you have trouble swallowing a diltiazem capsule whole, ask your doctor or pharmacist if it is safe for you to open the capsule and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. (2su.su)
do not crush, chew, break, or open an extended-release diltiazem tablet or capsule. (babas.se)
Pill with imprint MYLAN 6120 MYLAN 6120 is Pink, Capsule-shape and has been identified as Diltiazem Hydrochloride Extended-Release (SR) 120 mg. (drugs.com)

In the present study, design of oral immediate release tablets of Diltiazem hydrochloride by direct compression technique was carried out. (thepharmajournal.com)
Diltiazem hydrochloride tablets were formulated by using microcrystalline cellulose (diluent), potato starch, acacia (binder) and magnesium stearate (lubricant). (thepharmajournal.com)

Diltiazem may increase the effect and toxicity of cyclosporine. (illumina.com)

Because of its vasodilatory effects, diltiazem is useful for treating hypertension. (wikipedia.org)
Diltiazem hydrochloride is a first generation calcium channel blocker that is widely used in the therapy of hypertension and angina pectoris. (nih.gov)
Metoprolol and diltiazem are used to treat high blood pressure ( hypertension ), heart pain ( angina ), and abnormal heart rhythms . (hdkino.org)
Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. (internationaldrugmart.com)
Diltiazem, a benzothiazepine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. (illumina.com)
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Do not stop taking diltiazem without talking to your doctor. (medlineplus.gov)
If you stop taking diltiazem suddenly, your condition may become worse. (2su.su)

Many other medications may also interact with diltiazem, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
It may be noted that drugs other than those listed above may also interact with Diltiazem. (internationaldrugmart.com)
Grapefruit and grapefruit juice may interact with diltiazem and lead to potentially dangerous effects. (2su.su)

In New Jersey, all ALS care requires online medical control, including the administration of diltiazem. (medscape.com)
[ 3 ] However, previous studies have shown that IV administration of diltiazem can lead to a decrease in blood pressure because of its negative inotropic effect and its inhibition of intracellular calcium influx on vascular smooth muscle, leading to a decrease in total peripheral resistance. (medscape.com)
Chronic oral administration of diltiazem hydrochloride in doses of up to 240 mg/day has resulted in small increases in PR interval but has not usually produced abnormal prolongation. (nih.gov)

In congestive heart failure, patients with reduced ventricular function may not be able to counteract the negative inotropic and chronotropic effects of diltiazem, the result being an even higher compromise of function. (wikipedia.org)

Intravenous diltiazem can be effective to terminate AV nodal reentry supraventricular tachycardia but, in our experience, it is not recommended as the primary approach to stop AVNRT. (medscape.com)

Diltiazem may paradoxically increase ventricular rate in patients with Wolff-Parkinson-White syndrome because of accessory conduction pathways. (wikipedia.org)

Remember that immediate release diltiazem is always dosed TID/QID (3-4 times per day) whereas extended-release formulations are always dosed once daily. (rosalindfranklin.edu)

Like other calcium antagonists, diltiazem decreases sinoatrial and atrioventricular conduction in isolated tissues and has a negative inotropic effect in isolated preparations. (nih.gov)

Diltiazem is relatively contraindicated in the presence of sick sinus syndrome, atrioventricular node conduction disturbances, bradycardia, impaired left ventricle function, peripheral artery occlusive disease, and chronic obstructive pulmonary disease. (wikipedia.org)

Diltiazem, sold under the brand name Cardizem among others, is a calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. (wikipedia.org)
In the past, its use in the prehospital setting was limited because of various storage issues, particularly the need to store it at 2°C to 8°C. However, with the introduction of lyophilized diltiazem, it has been asserted that this medication can and should be used by prehospital providers in treating tachydysrhythmias. (medscape.com)
Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Diltiazem, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions. (internationaldrugmart.com)
In this episode, we "deep dive" into diltiazem, describing its most important drug facts, pharmacology and medicinal chemistry, pharmaceutics, AB compatibility, and important medication safety issues. (rosalindfranklin.edu)
Diltiazem belongs to a family of medications known as calcium channel blockersIt is used alone or with other medications to treat high blood pressure and anginachest painIt works by relaxing blood vessels and by reducing the workload of the heartThe injectable form of this medication is sometimes used in the hospital to bring abnormal heart rhythms under control. (larumbejoyeros.com)

A reflex sympathetic response, caused by the peripheral dilation of vessels and the resulting drop in blood pressure, works to counteract the negative inotropic, chronotropic and dromotropic effects of diltiazem. (wikipedia.org)
Diltiazem produces relaxation of coronary vascular smooth muscle and dilation of both large and small coronary arteries at drug levels which cause little or no negative inotropic effect. (nih.gov)

With SA node or AV conduction disturbances, the use of diltiazem should be avoided in patients with SA or AV nodal abnormalities, because of its negative chronotropic and dromotropic effects. (wikipedia.org)
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. (wikipedia.org)
Diltiazem slows atrioventricular (AV) nodal conduction, thereby prolonging the AV nodal refractory period. (medscape.com)

Diltiazem affects the movement of calcium into the cells of the heart and blood vessels. (mayoclinic.org)
Diltiazem relaxes blood vessels in the body and heart, thereby improving the blood flow. (internationaldrugmart.com)

Diltiazem is indicated for: Stable angina (exercise-induced) - diltiazem increases coronary blood flow and decreases myocardial oxygen consumption, secondary to decreased peripheral resistance, heart rate, and contractility. (wikipedia.org)
By blocking the entry of calcium, diltiazem decreases the force of contraction of the heart and its rate of contraction. (hdkino.org)

What if you miss a dose of Diltiazem? (internationaldrugmart.com)
Monitor for changes in the therapeutic and adverse effects of cilostazol if diltiazem is initiated, discontinued or dose changed. (illumina.com)
This effect may lead to more rapid absorption and an increase in the systemic exposure of diltiazem, and associated dose-related adverse reactions. (wellrx.com)

Diltiazem is one of the most common drugs that cause drug-induced lupus, along with hydralazine, procainamide, isoniazid, minocycline. (wikipedia.org)
Diltiazem is in a group of drugs called calcium channel blockers. (2su.su)

Diltiazem 24hr. (drugs.com)
er 240 mg. / diltiazem 24hr. (drugs.com)
What is the difference between Diltiazem 24HR er 120 mg and Diltiazem 24HR CD 120 mg. (drugs.com)

Should I take Amlodipine and Diltiazem at the same time? (drugs.com)

Diltiazem is in a class of medications called calcium-channel blockers. (medlineplus.gov)

Diltiazem hydrochloride is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). (nih.gov)
Diltiazem is metabolized by and acts as an inhibitor of the CYP3A4 enzyme. (illumina.com)
Diltiazem, a moderate CYP3A4 inhibitor, may increase the serum concentration of cilostazol by decreasing its metabolism. (illumina.com)
Diltiazem, a CYP3A4 inhibitor, may decrease the metabolism and clearance of Tamsulosin, a CYP3A4 substrate. (illumina.com)

I accidentally took 2 240 mg diltiazem pills this morning. (drugs.com)

Current data suggest that grapefruit juice has a limited effect on diltiazem bioavailability. (wellrx.com)

Concurrent use of fentanyl with diltiazem, or any other CYP3A4 inhibitors, as these medications decrease the breakdown of fentanyl and thus increase its effects. (wikipedia.org)

In a study involving single oral doses of 300 mg of diltiazem hydrochloride in six normal volunteers, the average maximum PR prolongation was 14% with no instances of greater than first-degree AV block. (nih.gov)
Diltiazem-associated prolongation of the AH interval is not more pronounced in patients with first-degree heart block. (nih.gov)

Of the 320 patients who received diltiazem, 42 patient encounters were excluded for incomplete data, yielding 278 patients for analysis. (medscape.com)

2] Diltiazem disetujui FDA 5 November 1982, Cardizem tablet oral (60MG, 120MG, 90MG, 30MG) dengan bahan aktif: Diltiazem Hydrochloride, diajukan oleh Bausch, dengan Jenis kimia: Tipe 1 - Entitas Molekuler Baru[2]. (idnmedis.com)

Avoid drinking alcohol while taking diltiazem. (2su.su)

Diltiazem is also sometimes used to treat certain types of arrhythmias (abnormal heart rhythms). (medlineplus.gov)
Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. (mayoclinic.org)
Side effects of diltiazem that are different from metoprolol include headache , rash , swelling of the legs and feet with fluid ( edema ), drowsiness, dizziness , liver dysfunction, overgrowth of the gums, and mildly abnormal liver tests . (hdkino.org)
Diltiazem is a calcium channel blocker (CCB) used to treat heart pain (angina), high blood pressure , and abnormal heart rhythms. (hdkino.org)

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Verapamil9

Tiazac1

Beta-blockers3

Take diltiazem8

Dosage7

Hypotension3

180MG4

Atrial fibrillation2

Cardizem CD1

Capsule5

Tablets2

Cyclosporine1

Hypertension15

Stop taking di2

Interact with diltiazem3

Administration of diltiazem3

Congestive heart f1

Intravenous1

Ventricular1

Release diltiazem1

Calcium antagonists1

Bradycardia1

Medication5

Dilation2

Conduction3

Blood vessels2

Decreases2

Dose3

Drugs2

24HR3

Amlodipine1

Medications called calcium-channel1

Inhibitor4

Pills1

Grapefruit juice1

CYP3A41

Prolongation2

Patient1

60mg1

Alcohol1

Abnormal4