Dilation and systolic dysfunction. Medical search. Frequent questions

0.05) dilation of the left ventricle, and reduction in ejection fraction compared to sham operated rats ( n = 4) on 7 T cardiac magnetic resonance imaging. (frontiersin.org)

Unfortunately, symptoms of alcoholic cardiomyopathy are not specific and common to other forms of heart failure and appear when dilatation and systolic dysfunction are consolidated. (nih.gov)
Idiopathic dilated cardiomyopathy (DCM) refers to congestive cardiac failure secondary to dilatation and systolic dysfunction (with or without diastolic dysfunction) of the ventricles (predominantly the left ventricle) in the absence of congenital, valvular, or coronary artery disease or any systemic disease known to cause myocardial dysfunction. (medscape.com)
In men, dilation prevails over hypertrophy, thus leading to an eccentric phenotype and resulting in a further increase in wall stress and neurohormonal activation that leads to progressive dilatation and systolic dysfunction with worse lengthy-time period outcomes. (homeloans8.com)

After the development of systolic dysfunction, left ventricular dilation and symptomatic heart failure, the jugular venous pressure may become elevated, the apical impulse would be displaced downward and to the left. (wikipedia.org)
Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function in the presence of a diastolic dysfunction. (wikipedia.org)
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)- Severe right atrial and ventricular dilation, systolic dysfunction, and all thinning. (vin.com)
Tachycardia induced cardiomyopathy is a decline in left ventricular function and left ventricular dilation as a result of chronic or frequently recurring paroxysmal tachycardia. (wikidoc.org)
In acute mitral regurgitation, patients are in sinus rhythm rather than atrial fibrillation and have little or no enlargement of the left atrium, no calcification of the mitral valve, no associated mitral stenosis , and in many cases little left ventricular dilation. (health.am)
Ventricular dilation (in response to increased end-diastolic volume) eventually reduces myocardial contractility. (the-medical-dictionary.com)
90 mmHg, right ventricular dilation and right ventricular hypokinesis (1). (pearls4peers.com)

In this case, congestive heart failure may represent underlying anemia (eg, Rh sensitization, fetal-maternal transfusion), arrhythmias (usually supraventricular tachycardia), or myocardial dysfunction (myocarditis or cardiomyopathy). (medscape.com)
In older children, congestive heart failure may be caused by left-sided obstructive disease (valvar or subvalvar aortic stenosis or coarctation), myocardial dysfunction (myocarditis or cardiomyopathy), hypertension, renal failure,[1] or, more rarely, arrhythmias or myocardial ischemia. (medscape.com)
More recently, speckle-tracking echocardiography has been shown to be effective in demonstrating subclinical myocardial dysfunction that is often not detected in standard echocardiography. (touchcardio.com)
2-5 More recently, speckle-tracking echocardiography (STE) has been used to detect subclinical myocardial dysfunction in patients with COVID-19. (touchcardio.com)

Etiologically, four main causes are responsible for the development of heart failure in diabetic cardiomyopathy: microangiopathy and related endothelial dysfunction, autonomic neuropathy, metabolic alterations that include abnormal glucose use and increased fatty acid oxidation, generation and accumulation of free radicals, and alterations in ion homeostasis, especially calcium transients. (wikipedia.org)
Transient ischemic dilation (TID) in the setting of abnormal stress-rest cardiac SPECT myocardial perfusion imaging (MPI) has been linked with increased cardiovascular risk. (snmjournals.org)
Both systolic and diastolic function of the left ventricle can become abnormal with aortic valve disease, and this chain of events is part of what we observe when deciding about timing for aortic valve surgery. (heart-valve-surgery.com)
However, it is established that Fontan patients have poor exercise capacity, associated with a greater risk of morbidity and mortality, in addition to decreased muscle mass, abnormal muscle function, and endothelial dysfunction contributing to disease progression. (stanford.edu)
Echocardiographic findings in COVID-19 patients include left or right ventricular dysfunction, including abnormal longitudinal strain and focal wall motion abnormalities, valvular dysfunction and pericardial effusion. (touchcardio.com)
RV pacing causes abnormal ventricular activation results in an inefficient contraction pattern with ventricular dyssynchrony and loss of myocardial work that may lead to LV dilation, systolic dysfunction, and clinical HF. (ijconline.id)
[ 9 ] In adults with T2DM, elevated liver enzymes were associated with abnormal brachial flow-mediated dilation, independent of whole body insulin sensitivity (IS) and other prognostic factors, suggestive of an increased CVD risk in adults with T2DM and liver disease. (medscape.com)

Myocardial strain imaging, a reproducible measure of LV systolic function, can identify subclinical LV dysfunction and patterns that suggest specific cardiomyopathies (eg, ischemic cardiomyopathy, amyloidosis, hypertrophic cardiomyopathy, chemotherapy-induced cardiotoxicity). (medscape.com)
In patients with ischemic cardiomyopathy, TTE may show segmental areas of systolic dysfunction that are typically localized to a coronary distribution. (medscape.com)
Causes of primary diastolic dysfunction include an anatomic obstruction that prevents ventricular filling (eg, pulmonary venous obstruction), a primary reduction in ventricular compliance (eg, cardiomyopathy, transplant rejection), external constraints (eg, pericardial effusion), and poor hemodynamics after the Fontan procedure (eg, elevated pulmonary vascular resistance). (medscape.com)
Dilated Cardiomyopathy (DCM)- Left ventricular systolic dysfunction, normal to reduced wall thickness, and atrial dilation. (vin.com)
Alcoholic cardiomyopathy is characterized by dilation and impaired contraction of one or both myocardial ventricles. (nih.gov)
Dilated cardiomyopathy (DCM) refers to congestive cardiac failure due to dilation and systolic dysfunction of the ventricles (predominantly the left ventricle). (medscape.com)
They are the most informative noninvasive tests for diagnosing the type of cardiomyopathy and the degree of dysfunction in the heart muscle. (medscape.com)
Incidence and predictors of right ventricular pacing-induced cardiomyopathy in patients with complete atrioventricular block and preserved left ventricular systolic function. (ijconline.id)
Our previous studies have demonstrated that Ca 2+ desensitizing catechin could correct diastolic dysfunction in experimental animals with restrictive cardiomyopathy. (biomedcentral.com)
Twelve pediatric cardiomyopathy patients with diastolic dysfunction were enrolled for the study. (biomedcentral.com)
This study indicates that Ca 2+ desensitizing green tea extract catechin, is helpful in correcting the impaired relaxation in pediatric cardiomyopathy patients with diastolic dysfunction. (biomedcentral.com)
Cardiomyopathy is a common heart disease in children that leads to cardiac dysfunction. (biomedcentral.com)
Among three major types of cardiomyopathies, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM) and restrictive cardiomyopathy (RCM), HCM and RCM share a common pathological feature, i.e. diastolic dysfunction whereas the main manifestation in DCM is systolic dysfunction [ 1 ]. (biomedcentral.com)
Using transgenic mouse model of cardiomyopathy, we have for the first time elucidated the relationship between Ca 2+ hypersensitivity caused by myofibril protein mutations and the following diastolic dysfunction in the heart [ 8 ]. (biomedcentral.com)
In the present study, we have tried to confirm the therapeutic effects of green tea extract catechin on diastolic dysfunction in pediatric cardiomyopathy patients by comparing the cardiac function before and after the treatment with catechin. (biomedcentral.com)
Dilated cardiomyopathy (DCM) is characterized by dilation of the left ventricle or double ventricle with impaired systolic function, and has a great impact on cardiac function. (cd-genomics.com)

A: Four-chamber dilation and hypertrophy are evident. (serdarbalci.com)
During the focused cardiac echocardiography, the following parameters were assessed: global cardiac systolic function, identification of ventricular enlargement or hypertrophy, assessment for pericardial effusion and estimation of the size and the respiratory changes of the inferior vena cava (IVC) diameter. (wustl.edu)
Dilation is more pronounced than hypertrophy, and the left ventricle is affected more often than the right ventricle. (medscape.com)

This endothelial dysfunction leads to impaired myocardial blood flow reserve as evidence by echocardiography. (wikipedia.org)
Over the years, several hypotheses were postulated to explain the endothelial dysfunction observed in diabetes. (wikipedia.org)
Endothelial dysfunction occurs when the cells lining the inside walls of blood vessels (the endothelium ) lose normal, healthy function. (lifeextension.com)
After six months, those taking magnesium had significantly improved endothelial function , which led to reductions in blood pressure and increased blood vessel dilation (widening). (lifeextension.com)
Smoking-induced CVD is attributed to endothelial dysfunction or harmful hemodynamic responses, including arterial stiffness [ 8 ]. (ksep-es.org)
To investigate if nonalcoholic fatty liver disease (NAFLD) confers added risk for endothelial dysfunction in these youth. (medscape.com)

In developed countries, more common causes of mitral regurgitation include myxomatous degeneration (eg, mitral valve prolapse with or without connective tissue diseases such as Marfan's syndrome), infective endocarditis, and subvalvular dysfunction (due to papillary muscle dysfunction or ruptured chordae tendineae). (health.am)
Nonrheumatic mitral regurgitation may develop abruptly, such as with papillary muscle dysfunction following myocardial infarction , valve perforation in infective endocarditis, or ruptured chordae tendineae in mitral valve prolapse. (health.am)

LV and left atrial dilation was observed in a number of patients without reduced EF, and may be an early stage in the development of the CMP. (jax.org)

Systolic blood pressure fell, on average, from 144 mmHg to 134 mmHg , and diastolic blood pressure decreased from 88 mmHg to 81 mmHg . (lifeextension.com)

Both systolic (strength of squeeze) and diastolic (ability to relax and fill) left ventricular dysfunction can lead to left atrial enlargement. (heart-valve-surgery.com)
The relationship between tachycardia and a reversible decline in left ventricular dysfunction was first described by Phillips and Levine in 1949 [1] . (wikidoc.org)

55%, coronary artery dilation, aneurysm, or ectasia, or elevated troponin above laboratory normal range or indicated as elevated in a clinical note. (cdc.gov)

Potassium and magnesium both promote blood vessel dilation, which lowers blood pressure. (dailytaker.com)

Left ventricular systolic dysfunction, the most common type of heart failure, is characterized by reduced stroke volume, incomplete ventricular emptying, cardiac dilation, and elevated left ventricular diastolic pressure. (the-medical-dictionary.com)
Diastolic dysfunction, which is less common, is characterized by a stiffened left ventricle that can't relax and fill sufficiently at normal diastolic pressure. (the-medical-dictionary.com)

A total of 16 transthoracic echocardiograms were comprehensively reviewed with an emphasis on chamber sizes, wall thickness, left ventricular (LV) and right ventricular (RV) systolic function, and valve function. (jax.org)
Three of these 4 patients also had severe generalized RV systolic dysfunction, whereas one had normal RV systolic function. (jax.org)
Patients who have decreased systolic or diastolic function (on the descending limb of the Frank Starling curve) will not respond to a fluid challenge, even if they are intravascularly depleted. (tactical-medicine.com)

The loss of myocytes leads to cardiac dilation and an increased afterload and wall tension, which results in further systolic dysfunction. (medscape.com)

Inhalation exposure to three-dimensional printer emissions stimulates acute hypertension and microvascular dysfunction. (cdc.gov)
Histologically, myocyte disarray, scarring and microvascular dysfunction are the hallmarks of HCM. (1library.net)

Failure to institute therapy leads to progression of thyrotoxicosis, emaciation and severe cardiac and metabolic dysfunction and eventual death. (vin.com)

By echocardiographic examination, LV diastolic dysfunction was evident in 35 (40%) patients. (1library.net)

Over-stretching of the left ventricle (LV) causes impaired LV dilation, leading to pulmonary edema, pulmonary hypertension, and right ventricular dysfunction. (tactical-medicine.com)

Transthoracic echocardiography , the most widely available initial standard of care test for ventricular dysfunction, can help differentiate ischemic and nonischemic etiologies of cardiomyopathies. (medscape.com)
Eligible patients were ≤ 18 years of age, were diagnosis as HCM or RCM, and had evidence of diastolic dysfunction confirmed by echocardiography and clinical manifestations. (biomedcentral.com)
Additionally, the presence of diastolic dysfunction and mitral regurgitation were obtained by echocardiography and also correlated to AF. (1library.net)

Systolic mitral murmur is not uncommon in these cases. (wikipedia.org)
Mitral regurgitation (MR) is caused by the retrograde flow of blood from the left ventricle (LV) into the left atrium (LA) through the mitral valve (MV), causing a systolic murmur heard best at the apex of the heart with radiation to the left axilla. (nih.gov)

The loss of cardiomyocytes also results in higher wall stress, coupled with reduced physiological adaptability of the dystrophin-deficient myocardium, leading to LV dilation and systolic dysfunction [ 3 ]. (biomedcentral.com)

Transient ischemic dilation (TID) on stress SPECT myocardial perfusion imaging (MPI) is defined as the apparent presence of left ventricular (LV) dilation on poststress relative to rest images. (snmjournals.org)

In Michael's case, without knowing about the presence of any of these other factors, left atrial enlargement is due to dysfunction of the left sided valves. (heart-valve-surgery.com)

NIID is a heterogeneous disorder with variable clinical manifestations including cognitive impairment, cerebellar ataxia, parkinsonism, paroxysmal symptoms, autonomic dysfunction, and muscle weakness. (biomedcentral.com)

Combined pulmonary insufficiency (PI) and stenosis (PS) is a common long-term sequela after repair of many forms of congenital heart disease, causing progressive right ventricular (RV) dilation and failure. (jci.org)

Our study provided the first in vivo evidence linking GGC repeat expansions within NOTCH2NLC to cardiac abnormalities and highlighted the contribution of mitochondrial dysfunction in the development of cardiac abnormalities. (biomedcentral.com)

Although plasma miR-21 was upregulated with diastolic dysfunction, it was downregulated with the onset of systolic dysfunction), correlating with RV fibrosis. (jci.org)
B ) The expression of miR-21 positively correlated with the degree of RV fibrosis as diastolic dysfunction progressed, but that correlation was lost once systolic dysfunction developed. (jci.org)

Male SHRs from 15 months of age exhibited left ventricular wall thinning and chamber dilation, together with systolic and diastolic dysfunction and increased cardiac stiffness and increased erythrocyte superoxide production, which were not present in the female SHRs. (edu.au)

Cardiac ultrasound (POCUS): look for right or left ventricular strain or dilation. (aneskey.com)
This study aimed to investigate whether AR aggravates LV deformation dysfunction and to identify independent factors affecting the global peak strain (PS) of LV remodeling in patients with type 2 diabetes mellitus (T2DM) who presented with AR and those without T2DM. (biomedcentral.com)
The T2DM patients with AR had a lower LV global PS, peak systolic strain rate (PSSR), and peak diastolic strain rate (PDSR) in three directions than those without AR and non-T2DM controls. (biomedcentral.com)

In fact, diastolic dysfunction was associated with worse outcomes than systolic dysfunction ( Landesberg 2012 ). (tactical-medicine.com)
Therefore, it is important to investigate cardiac dysfunction in patients with T2DM who present with AR before the occurrence of adverse events to reduce cardiovascular risk and improve outcomes. (biomedcentral.com)

Additionally, we and others have reported that inhalation of xenobiotic particles in this size range is associated with an array of cardiovascular dysfunctions. (cdc.gov)
Specifically, previous studies have demonstrated that smoking cessation is likely to restore cardiovascular dysfunction and attenuate CVD-medi-ated mortality [ 13 , 14 ]. (ksep-es.org)

Many septic patients have preceding heart failure, about 54% with diastolic dysfunction and 23% with systolic dysfunction, which can be worsened by fluid administration ( Landesberg 2012 ). (tactical-medicine.com)
Multivariate analysis demonstrated that LA volume and presence of diastolic dysfunction were the only independent determinant of AF in HCM patients (p = 0.006, p = 0.01 respectively). (1library.net)
LA dilation is the strongest determinant of AF in HCM patients, and is related to the extent of LGE in the LV, irrespective of LV mass. (1library.net)

Both diastolic and systolic dysfunction develops in all four chambers as well [2] . (wikidoc.org)

Animal models demonstrate that sustained atrial or ventricular pacing results in dilation of all four cardiac chambers with thinning of the left and right ventricular walls. (wikidoc.org)

Reducing angiotensin II formation leads to arterial and venous dilation, which reduces arterial and venous pressures. (cvpharmacology.com)

Surgeon Q&A: Can Left Atrium Dilation Be Reversed After Heart Valve Surgery? (heart-valve-surgery.com)
a normal heart size suggests diastolic dysfunction. (the-medical-dictionary.com)

2] Systolic dysfunction is characterized by diminished ventricular contractility that results in an impaired ability to increase the stroke volume to meet systemic demands. (medscape.com)
Factors such as anatomic stresses (eg, coarctation of the aorta) that contribute to an increased afterload (end-systolic wall stress), as well as neurohormonal factors that increase systemic vascular resistance, also lead to systolic dysfunction. (medscape.com)

Anatomy22

Organisms7

Diseases58

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment76

Psychiatry and Psychology3

Phenomena and Processes39

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena2

Humanities1

Information Science5

Health Care42

Geographicals1

Ejection fraction1

Dilatation and systolic dysfunction3

Ventricular dilation7

Myocardial dysfunction4

Abnormal7

Cardiomyopathy16

Hypertrophy3

Endothelial6

Papillary muscle dysfunction2

Atrial dilation1

MmHg1

Left ventricular dysfunction2

Coronary1

Blood vessel1

Diastolic pressure2

Function3

Leads to cardiac1

Microvascular dysfunction2

Severe1

Echocardiographic1

Pulmonary hypertension1

Echocardiography3

Murmur2

Myocardium1

Ischemic1

Enlargement1

Autonomic1

Progressive1

Mitochondrial1

Fibrosis2

Stiffness1

Strain3

Outcomes2

Cardiovascular2

Patients3

Develops1

Cardiac chambers1

Arterial1

Heart2

Systemic2