• Tournefort calls the taxon Digitalis Hispanica, purpurea, minor. (wikipedia.org)
  • In addition to foxglove Digitalis purpurea , the research team also studied another plant species, the rubber tree Calotropis procera . (sciencedaily.com)
  • The study focused on two plant species: foxglove (Digitalis purpurea) and the rubber tree (Calotropis procera). (expresshealthcaremgmt.com)
  • Lily of the valley is used by European herbalists in place of common foxglove (Digitalis purpurea) . (herbsandremedies.club)
  • Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander (common oleander), Thevetia peruviana (yellow oleander), Convallaria majalis (lily of the valley), Urginea maritima and Urginea indica (squill), Strophanthus gratus (ouabain), Apocynum cannabinum (dogbane), and Cheiranthus cheiri (wallflower). (medscape.com)
  • Digitalis minor is a species of flowering plant in family Plantaginaceae, which has been called dwarf Spanish foxglove. (wikipedia.org)
  • Cardiac glycoside biosynthesis has evolved in diverse lineages including foxglove (Digitalis, Plantaginaceae) and milkweeds (Apocynaceae), but the full biosynthetic pathway has not been described in any species. (bvsalud.org)
  • We identified the candidate genes involved in cardenolide biosynthesis by comparative analysis of the two plant species. (sciencedaily.com)
  • The research team plans to continue studying the downstream steps of cardenolide biosynthesis and hope to solve this complex puzzle soon. (expresshealthcaremgmt.com)
  • Therapeutic and toxic effects of digitalis: William Withering, 1785. (medscape.com)
  • Digitalis lanata plants are used for the isolation of digoxin. (nzdl.org)
  • Our purpose was to determine the effect of progressive i.v. infusion of either ASI-222, a polar aminocardenolide agent, or digoxin, a neutral cardenolide, on cardiac sympathetic, efferent vagal, and carotid sinus nerve activity. (elsevierpure.com)
  • A hypersensitivity reaction to other digitalis preparations usually constitutes a contraindication to digoxin. (wikidoc.org)
  • Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. (sciencedaily.com)
  • Well-known examples of this class of substances obtained from plants are cardenolides. (sciencedaily.com)
  • Although these two plants belong to different plant families, they both produce large amounts of cardenolides. (sciencedaily.com)
  • The structures of the cardenolides in these plants have both overlapping and divergent profiles. (sciencedaily.com)
  • Scientists at the Max Planck Institute for Chemical Ecology have made significant progress in understanding the biosynthetic pathway responsible for the formation of cardenolides in plants. (expresshealthcaremgmt.com)
  • Cardenolides are a class of medically valuable steroids obtained from plants. (expresshealthcaremgmt.com)
  • Despite belonging to different plant families, both plants produce high levels of cardenolides. (expresshealthcaremgmt.com)
  • This was the first step in the cardenolide biosynthetic pathway in these two only distantly related plants. (globalplantcouncil.org)
  • Cardenolides are found in a number of flowering plants. (vetinfo.com)
  • The infusion prepared using the flowers and roots of lily of the valley is an effective substitute for digitalis (which is obtained from plants belonging to the Digitalis species). (elmaskincare.com)
  • In the absence of toxins from a preferred food (milkweed seeds), large milkweed bugs fed on nutritionally adequate non-toxic seeds, but supplemented their diet by feeding on nutritionally poor, but cardenolide-rich milkweed leaf and stem tissues. (bvsalud.org)
  • In order to study the influence of the hypothalamic-pituitary-adrenal axis on the levels of endogenous digitalis-like substances (EDLS) in plasma and urine, eight healthy subjects (25-40 years old) were given dexamethasone 1 mg orally and tetracosactide (an ACTH analog) 0.25 mg i.v., on separate occasions. (lu.se)
  • The biological digitalis-like activity in the urine measured by the 86Rb-uptake assay was decreased, but not to a statistically significant degree. (lu.se)
  • In addition to their effect on the contractility of the heart, cardenolides have been used with great success in recent years for the treatment of various cancers. (sciencedaily.com)
  • Urine was collected before and after each test dose, and analysed for cortisol levels by gas chromatography/mass spectrometry, and for digitalis-like activity both by RIA and by a bioassay measuring 86Rb-uptake into red blood cells. (lu.se)
  • Digitalis is used as a medication to regulate a person's heart function, but an overdose leads to cardiac arrest. (vetinfo.com)
  • Biotransformation of cardenolides by plant cell cultures indicate a new possibility of making better use of these by-products. (nzdl.org)
  • The toxic principles in the kalanchoe plant are cardenolides and bufadienolides, which are both cardiac glycoside toxins that are similar to digitalis. (github.io)
  • Differences in toxicity and extracardiac effects exist between the oleander and digitalis cardenolides, however. (nih.gov)
  • This increase in sympathetic activity may be an important factor in digitalis toxicity. (nih.gov)
  • Digitalis minor is a species of flowering plant in family Plantaginaceae, which has been called dwarf Spanish foxglove. (wikipedia.org)
  • Digitoxin is a glycoside isolated from leaves of various species of Digitalis genus that are commonly called foxgloves. (ac.ir)
  • This poison is similar to digitalis, which can be used to help people with heart problems, but can kill people if they consume too much of it. (gowanusballroom.com)
  • 13. Digitalis structure-activity relationship analyses. (nih.gov)
  • Some of the cardenolides showed antiproliferative activity against human colon cancer, breast cancer, lung cancer and epidermoid carcinoma cell lines, as well as anti-oestrogenic activity. (findmeacure.com)