• C-13 is a stable carbon isotope. (lookformedical.com)
  • Deuterium (chemical symbol D or ²H) is a stable isotope of hydrogen with a nucleus containing one neutron and one proton. (newenergyandfuel.com)
  • However, because isotopes have similar physical and chemical properties, the process of filtering deuterium out of the natural isotopic mixture of hydrogen is at present both difficult and expensive. (newenergyandfuel.com)
  • Voltage-gated proton channels represent a specific subset of proton channel that have voltage- and time-dependent gating like other ion channels, but differ from most ion channels in their extraordinarily high selectivity, tiny conductance, strong temperature and deuterium isotope effects on conductance and gating kinetics, and insensitivity to block by steric occlusion. (typeset.io)
  • However, they differ from most ion channels in their extraordinarily high selectivity, tiny conductance, strong temperature and deuterium isotope effects on conductance and gating kinetics, and insensitivity to block by steric occlusion. (typeset.io)
  • Another fissile isotope, uranium-233 , can be produced from natural thorium and is also important in nuclear technology. (ipfs.io)
  • In sufficient concentration, these isotopes maintain a sustained nuclear chain reaction . (ipfs.io)
  • It is an irreplaceable raw material, widely employed in industrial and scientific research applications, ranging from isotope tracing to neutron scattering, as well as nuclear fusion. (newenergyandfuel.com)
  • Yeasts possess rather rigid, thick cell walls, have a well-organized nucleus with a nuclear membrane (eukaryotic), and have no motile stages. (biologydiscussion.com)
  • Uranium is weakly radioactive because all its isotopes are unstable (with half-lives of the six naturally known isotopes, uranium-233 to uranium-238, varying between 69 years and 4.5 billion years). (ipfs.io)
  • Am-Americum are radioactive isotopes and have a half-life of 7,950 years. (mighty-90.com)
  • At-Atatine is a radioactive isotope with an extremely short half-life of 7.2 to 8 hours. (mighty-90.com)
  • Previous work has identified a set of zinc transporters involved in Drosophila dietary zinc absorption. (biomedcentral.com)
  • Transdermal absorption experiments for each formulation were performed using a diffusion cell and a slice of chicken skin as model at 32°C for 3 hours. (ijpsr.com)
  • Crystalline zinc oxide is thermochromic, changing from white to yellow when heated in air and reverting to white on cooling. (wikipedia.org)
  • In a carbothermic reaction, heating with carbon converts the oxide into zinc vapor at a much lower temperature (around 950 °C). ZnO + C → Zn(Vapor) + CO Zinc oxide crystallizes in two main forms, hexagonal wurtzite and cubic zincblende. (wikipedia.org)
  • Diffusion of gases. (eduvidya.com)
  • This smart material system could only be tested experimentally because the research team, headed by Michael Hirscher, had designed an apparatus in which they can analyze the stored quantities of different isotope gases directly with the aid of a mass spectrometer at cryogenic conditions. (newenergyandfuel.com)
  • In contrast to soluble chemicals, cadmium oxide particles on a cm2/ml media basis, but are only ~50 particles can settle, diffuse, and aggregate differentially accord- times more potent when differences in delivery to adherent cells are ing to their size, density, and surface physicochemistry. (cdc.gov)
  • Ryunosuke Okuda, Koichi Suematsu, Ken Watanabe, Kengo Shimanoe, Highly Porous Chitosan-derived Nitrogen-Doped Carbon Applicable for High-performance Gas Diffusion Type Oxygen Electrode, Chemistry Letter , 10.1246/cl.200748, 2021.01. (kyushu-u.ac.jp)
  • Other ancient mats have been studied, but Westall says evidence that they photosynthesized has been indirect - either being assumed from their carbon-isotope composition, which Westall argues can also come from non-photosynthetic microbes, or by looking closely at the mat's structure and seeing microbe-like structures. (uncommondescent.com)
  • of somewhat related interest: As well, in conjunction with bacteria, geological processes helped detoxify the earth of dangerous levels of metal: The Concentration of Metals for Humanity's Benefit: Excerpt: They demonstrated that hydrothermal fluid flow could enrich the concentration of metals like zinc, lead, and copper by at least a factor of a thousand. (uncommondescent.com)
  • Concentration cells. (eduvidya.com)
  • At the organismal level, the physiological function of zinc transporters was shown to be essential for systemic zinc homeostasis and health [ 27 , 28 ]. (biomedcentral.com)
  • Generally speaking, Zip proteins function in transporting zinc into the cytoplasm from extra- or intracellular vesicles, while ZnT proteins transport zinc in opposite orientations to efflux zinc out of the cytosol [ 15 , 16 ]. (biomedcentral.com)
  • This occurs in tissue cell cytosol, with high activity in the duodenum, liver , and kidney. (lookformedical.com)
  • Additionally, EBN contains essential elements such as calcium (1298 ppm), sodium (650 ppm), magnesium (330 ppm), potassium (110 ppm), phosphorous (40 ppm), zinc, and iron (30 ppm) (Marcone 2005) . (researchgate.net)
  • The Romans produced considerable quantities of brass (an alloy of zinc and copper) as early as 200 BC by a cementation process where copper was reacted with zinc oxide. (wikipedia.org)
  • From the 12th to the 16th century zinc and zinc oxide were recognized and produced in India using a primitive form of the direct synthesis process. (wikipedia.org)
  • Arsenic metabolism is affected by tissue and blood levels of zinc, selenium, arginine, choline, methionine, taurine, and quaniacetic acid, all of which affect methyl-group metabolism and polyamine synthesis which is the site of arsenic function in human physiology. (mighty-90.com)
  • Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine. (wikipedia.org)
  • Bae KM, Wang H, Jiang G, Chen MG, Lu L, Xiao L. Protein kinase C epsilon is overexpressed in primary human non-small cell lung cancers and functionally required for proliferation of non-small cell lung cancer cells in a p21/Cip1-dependent manner. (famri.org)
  • Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain. (wikipedia.org)
  • A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. (lookformedical.com)
  • ZnO decomposes into zinc vapor and oxygen at around 1975 °C with a standard oxygen pressure. (wikipedia.org)
  • In laboratory in cultivated cells, lack of oxygen triggers irregular, disturbed DNA syntheses. (iamoxygen.com)
  • Hydrogen was discovered by the English chemist and physicist Henry Cavendish in 1766 when he was experimenting with metals ( iron , zinc and tin ) and acids. (zxc.wiki)
  • Although it occurs naturally as the mineral zincite, most zinc oxide is produced synthetically. (wikipedia.org)
  • Uranium-235 has the distinction of being the only naturally occurring fissile isotope . (ipfs.io)
  • In this work, we screened all the potential zinc transporter Zip (SLC39) and ZnT (SLC30) members for their likely roles in zinc excretion in Malpighian tubules, an insect organ functionally analogous to mammalian kidneys. (biomedcentral.com)
  • Zip71B/dZip5 is localized to the plasma membrane at the basolateral side of the tubules, and is functionally epistatic to the apically localized ZnT35C in regulating the tubule zinc homeostasis. (biomedcentral.com)
  • Accordingly, there is an unmet need for targeting of solid tumor cells for the treatment of malignant diseases that will show an affinity for cancer cells, deliver therapeutic payloads that inhibit proliferation and/or destroy cancerous tumor cells without inhibiting and/or destroying normal cells. (justia.com)
  • In some embodiments, aspects of the invention are based on the selective tropism of NSPs described herein for tumor cells. (justia.com)
  • The proliferation of tumor cells is characterized by inflammation of tumor sites, the ability of tumor cells to evolve HSPG (heparan sulphate proteoglycans) in a similar manner to basal membrane Keratinocytes, and the presence of various growth factor receptors known to congregate at the surface of tumor cells. (justia.com)
  • Ali MA, Choy H, Habib AA, Saha D. SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor. (famri.org)
  • Isoforms of Wilms' tumor suppressor gene (WT1) have distinct effects on mammary epithelial cells. (famri.org)
  • Tubule-specific knockdown of Zip71B /dZip5 reduces zinc accumulation in the tubules, but increases zinc levels in the body, resulting in survival defect under zinc excess conditions. (biomedcentral.com)
  • Inappropriate kinase activity triggers a variety of biological cellular responses relating to cell growth, cell differentiation, cell function, survival, apoptosis, and cell mobility implicated in the aforementioned and related diseases. (justia.com)
  • Here we develop and apply the principles of their evolution from systems principally for evaluating mechanism dosimetry in vitro and outline an approach for simulation of of toxicity to high-throughput systems for rapid and cost-effective nanoparticle particokinetics in cell culture systems. (cdc.gov)
  • The success of zinc white paint was due to its advantages over the traditional white lead: zinc white is essentially permanent in sunlight, it is not blackened by sulfur-bearing air, it is non-toxic and more economical. (wikipedia.org)
  • Furthermore, Zip71B/dZip5 expression is regulated by zinc so that, in response to toxic levels of zinc, the tubules can increase zinc efflux capability. (biomedcentral.com)
  • Accordingly, NSPs described herein are useful for delivering toxic agents to tumors with reduced risk to healthy cells. (justia.com)
  • However, zinc excretion and reabsorption, the other two important processes to maintain zinc homeostasis, are not as well understood. (biomedcentral.com)
  • Finally, using a tubule calcification model, we were able to show that knockdown of Zip71B/dZip5 or ZnT35C was able to mitigate stone formation, consistent with their roles in tubular zinc homeostasis. (biomedcentral.com)
  • Maintenance of zinc homeostasis is very important for human health. (biomedcentral.com)
  • Zinc homeostasis is tightly controlled by a series of transporter proteins that are broadly categorized into two major families, the Slc39a or Zip family and the Slc30a or ZnT family. (biomedcentral.com)
  • 2019. Leaf photosynthetic capacity is regulated by the interaction of nitrogen and potassium through coordination of CO2 diffusion and carboxylation . (hutton.ac.uk)
  • JAK enzymes have been shown to be important in the differentiation and function of multiple cell types important in inflammatory disease and autoimmune disease including natural killer cells, B cells, and T helper cell types. (justia.com)
  • Pseudomycelia vary in their complexity from very primitive, in which the numbers of cells are limited and where there is little or no differentiation among these cells, to other forms where cells comprising the main chain are rather elongated and the buds arise in clusters on the shoulder of these elongated stem cells. (biologydiscussion.com)
  • Zinc is an essential micronutrient that serves as a catalytic or structural component of numerous enzymes and other proteins and accordingly contributes to a variety of fundamental biological processes [ 1 - 5 ]. (biomedcentral.com)
  • 16. A living cell has a protoplasm which is water based and demarcated by a lipid bilayer membrane. (pharmatutor.org)
  • The RHL-1 subunit of the asialoglycoprotein receptor of thyroid cells: cellular localization and its role in thyroglobulin endocytosis. (cnr.it)
  • The yeast thallus (vegetative body) in its simplest form is a single cell or perhaps one with a bud still attached as exemplified by Saccharomyces cerevisiae. (biologydiscussion.com)
  • Our results start to sketch out a relatively complete picture of the zinc excretion process in Drosophila Malpighian tubules, and may provide a reference for relevant mammalian studies. (biomedcentral.com)
  • Thus, in the process of destroying or inhibiting the rapidly dividing cancer cells, many of the healthy cells are also damaged. (justia.com)
  • The invention also provides nanosphere particle preparations that are useful for selectively delivering therapeutic, diagnostic, and/or other agents to cancer cells of subjects without eliciting a serotype-specific immunogenic response in the subjects. (justia.com)
  • For example, those agents that target actively dividing cells are not able to discriminate between actively dividing cancer cells and actively dividing healthy cells. (justia.com)
  • Many therapeutic agents cannot be delivered effectively to treat cancerous cells by conventional means such as ingestion, injection, inhalation, and topical application because many of these agents are subject to rapid degradation. (justia.com)
  • Simultaneously, imidazole molecules (IM) were employed into the MOF-74-Ni channel as a diffusion barrier, effectively reducing the aperture size and repeatedly blocking H2 diffusion, resulting in the KQS effect. (newenergyandfuel.com)
  • It is nearly insoluble in water, but it will dissolve in most acids, such as hydrochloric acid: ZnO + 2 HCl → ZnCl2 + H2O Solid zinc oxide will also dissolve in alkalis to give soluble zincates: ZnO + 2 NaOH + H2O → Na2[Zn(OH)4] ZnO reacts slowly with fatty acids in oils to produce the corresponding carboxylates, such as oleate or stearate. (wikipedia.org)
  • The most common isotopes in natural uranium are uranium-238 (which has 146 neutrons and accounts for over 99%) and uranium-235 (which has 143 neutrons). (ipfs.io)
  • While the definition of yeasts varies somewhat according to author, they are generally defined as fungi which, in a stage of their life cycle, occur as single cells, reproducing commonly by budding or less frequently by fission. (biologydiscussion.com)
  • Generally organisms with plurinucleate cells or those producing black pig-ments or producing asexual spores borne on distinct aerial structures are excluded. (biologydiscussion.com)
  • Similar to chain formation, a pseudomycelium (false mycelium) may be formed when, instead of the bud breaking away from the mother cell at maturity, it elongates and continues to bud in turn. (biologydiscussion.com)
  • In the study, the research team has reported a highly effective hydrogen isotope separation system based on porous metal-organic frameworks (MOFs) through a simple post-modification strategy. (newenergyandfuel.com)
  • When mixed with a strong aqueous solution of zinc chloride, ZnO forms cement-like products best described as zinc hydroxy chlorides. (wikipedia.org)
  • CEO download women and the economic miracle gender and work in postwar japan california series on social choice of Interest and current Zinc top: An late discolouration and G-protein-coupled p. (ogtechnology.com)
  • For example, during the late 1890s and early 1900s, some artists used zinc white as a ground for their oil paintings. (wikipedia.org)
  • Zinc is an essential metal involved in many physiological processes. (biomedcentral.com)
  • Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. (famri.org)
  • We also characterized the role of dZnT1 (CG17723) in zinc reabsorption in Malpighian tubules. (biomedcentral.com)
  • Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. (lookformedical.com)
  • The early investigators described yeasts as being round to oval in appear-ance and noted that they divided by budding to form daughter cells. (biologydiscussion.com)