Differentiation of adipose. Medical search. Frequent questions

Among these, adipose-derived stem cells (ADSCs) are a type of mesenchymal stem cell isolated from adipose tissue, which has the advantages of abundant storage in vivo , easy acquisition, and expansion [ 13 - 15 ]. (hindawi.com)
Differentiation was compared to mesenchymal stem cells derived from human bone marrow, which is known to differentiate into adipocyte, osteocyte, and chondrocyte lineages. (jove.com)
Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
Induced osteogenesis of adipose-derived mesenchymal stem cells (AMSCs) has been used to facilitate bone regeneration. (aging-us.com)
A specific population of adipose-derived stem cells (ASCs) is expected to be an alternate source of bone marrow-derived mesenchymal stem cells (BMSCs). (jarde.jp)
To evaluate the effect of Exendine-4 (EX-4), a Glucagon-like peptide 1 (GLP-1) receptor agonist, on the differentiation of insulin-secreting cells (IPCs) from rat adipose-derived mesenchymal stem cells(ADMSCs). (celljournal.org)
Surface Functionalized Polyaniline Nanofibers:Chitosan Nanocomposite for Promoting Neuronal-like Differentiation of Primary Adipose Derived Mesenchymal Stem Cells and Urease Activity. (bvsalud.org)
Surface functionalization mediated improved cell - biomaterial interactions led to improved viability, adhesion, and spreading of primary adipose derived mesenchymal stem cells (ADMSCs) as well as improved immunocompatibility . (bvsalud.org)
Mesenchymal stem cells (MSCs) also known as mesenchymal stromal cells or medicinal signaling cells are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue). (wikipedia.org)
The aim of this study was to differentiate canine adipose-derived mesenchymal stem cells (ADMSCs) into insulin-producing cells by using culture media with different compositions to determine the most efficient media. (sdlifesciences.com)
Adipose-derived mesenchymal stem cells from groups 1 to 5 gradually became round in shape and gathered in clusters. (sdlifesciences.com)
The MSC research team focuses on the characterisation primarily of adipose-derived mesenchymal stem/stromal cells (MSCs), the comparison of culture methods towards culturing transplantation-quality MSCs, and understanding their utility in different transplant settings. (up.ac.za)
Investigating the homing and healing properties of adipose-derived mesenchymal stromal cells using a model of would repair. (up.ac.za)
BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. (atlasgeneticsoncology.org)
Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
We designed a study to find theoretical evidence for the induction, movement, fusion, proliferation, and safety of human adipose mesenchymal stem cells (hADSCs) in intraocular application. (molvis.org)
Therefore, in this study, we assessed the ability of human adipose mesenchymal stem cells (hADSCs) to express the characteristics of ECs after induction in vitro to evaluate the theoretical feasibility of maintaining or restoring the function of ECs after intraocular application. (molvis.org)
Mariano García Arranz has the following conflict of interest: MGA is inventor on 2 patents entitled "Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue" (10157355957US) and "Use of adipose tissue-derived stromal stem cells in treating fistula" (US11/167061). (wjgnet.com)
Given this, the ALINE MANICA2 cryopreservation of adipose tissue-derived mesenchymal stem cells (ADMSCs) could be a JULIANA CRISTINA SCHMIDT2 way to collect them in one surgical procedure and after performing fractional fat grafting. (bvsalud.org)

In this study, we verified that exosomes derived from osteogenically differentiated ADSCs can promote osteogenic differentiation of ADSCs. (hindawi.com)
Moreover, we found that these differentially expressed exosomal miRNAs connect osteogenic differentiation to processes such as axon guidance, MAPK signaling, and Wnt signaling. (hindawi.com)
This study confirms that alterations in the expression of exosomal miRNAs can promote osteogenic differentiation of ADSCs, which also provides the foundation for further research on the regulatory functions of exosomal miRNAs in the context of ADSC osteogenesis. (hindawi.com)
Long noncoding RNAs (lncRNAs) are emerging regulators for osteogenic differentiation from AMSCs. (aging-us.com)
In the current study, we found that lncRNA-PAGBC was a specific lncRNA that significantly upregulated during osteogenic differentiation of AMSCs based on published database. (aging-us.com)
HP increased lncRNA-PAGBC, which is a competitive endogenous RNA (ceRNA) that binds to the osteogenesis-inhibitory microRNA, miR-133b, to regulate osteogenic differentiation of AMSCs. (aging-us.com)
Suppression of RUNX2 by miR-133b caused impaired osteogenic differentiation of AMSCs. (aging-us.com)
Together, these data suggest that HP induces osteogenic differentiation of AMSCs through increasing lncRNA-PAGBC. (aging-us.com)
To accelerate their osteogenic differentiation, we overexpressed the osteogenic transcription factor Cbfa1 (Core binding factor alpha-1, Til-1) gene using an adenovirus vector in rat ASCs. (jarde.jp)
Collagen-PCL Sheath-Core Bicomponent Electrospun Scaffolds Increase Osteogenic Differentiation and Calcium Accretion of Human Adipose-Derived Stem Cells. (ncsu.edu)
Human adipose-derived stem cells (hASCs) are an abundant cell source capable of osteogenic differentiation, and have been investigated as an autologous stem cell source for bone tissue engineering applications. (ncsu.edu)

How the UPP is altered in aging adipose tissue and adipocyte differentiation and the effects of proteasome inhibition on adipocyte homeostasis and differentiation are critical issues to elucidate experimentally. (elsevierpure.com)

Furthermore, MSCs can undergo osteogenic, adipogenic and chondrogenic differentiation ex vivo. (wikipedia.org)

Culture expansion of adipose derived stromal cells. (nih.gov)
Adipose derived stromal cells (ASCs) are a rich and convenient source of cells for clinical regenerative therapeutic approaches. (nih.gov)

They were initially found in the bone marrow [ 11 ] but can also be found in other tissues, such as adipose, periosteum, muscle, placenta, and trabecular bone [ 12 ]. (hindawi.com)
Moreover, regenerated adipose-like tissues are needed for soft tissue reconstruction in addition to in vitro models. (tuni.fi)
The term encompasses multipotent cells derived from other non-marrow tissues, such as placenta, umbilical cord blood, adipose tissue, adult muscle, corneal stroma, or the dental pulp of deciduous (baby) teeth. (wikipedia.org)
Impairments in the UPP occur during the aging of a variety of tissues, although little is known in regards to age-related alterations to the UPP during the aging of adipose tissue. (elsevierpure.com)
Reduced cystathionine-γ-lyase (CSE) expression is involved in high glucose induced MMP14 expression in adipocytes and adipose tissues. (sdlifesciences.com)
In the present study, we investigate the effect of reduced cystathionine-γ-lyase (CSE) expression in high glucose induced metalloproteinases14 (MMP14) expression in adipocytes and visceral adipose tissues. (sdlifesciences.com)
Diabetic mice were prepared by injections of STZ and the expression of CSE, MMP14 in visceral adipose tissues were determined. (sdlifesciences.com)
In adipose tissues of diabetic mice, the mRNA and protein expression of MMP14 increased while the mRNA and protein expression of CSE decreased. (sdlifesciences.com)
In lipodystrophy there is insufficient adipose tissue to absorb the postprandial influx of fatty acids, so these fatty acids will again be directed to other tissues. (cambridge.org)
This view of the link between adipose tissue and insulin resistance emphasises the important role of adipose tissue in 'buffering' the daily influx of dietary fat entering the circulation and preventing excessive exposure of other tissues to this influx. (cambridge.org)

Human adipose-derived stem cells differentiated in hydrogel and obtained features found in native, mature adipocytes, including intracellular lipid droplets and spherical shape. (tuni.fi)
The standard test to confirm multipotency is differentiation of the cells into osteoblasts, adipocytes and chondrocytes as well as myocytes. (wikipedia.org)
Adipogenesis continues throughout the life of adipose tissue, with continual differentiation of preadipocytes essential to maintaining tissue function during aging, and UPP alterations in mature adipocytes are likely to directly modulate adipose function during aging. (elsevierpure.com)
Additionally, we show that multiple changes in the UPP occur during the differentiation of 3T3-L1 cells into adipocytes. (elsevierpure.com)
Taken together, these data demonstrate that changes in the UPP occur in response to adipose aging and adipogenesis and strongly suggest that proteasome inhibition is sufficient to decrease adipose differentiation, as well as increasing oxidative stress in mature adipocytes, both of which probably promote deleterious effects on adipose aging. (elsevierpure.com)
Oil red O staining showed that Ad36 induced the differentiation of hAMSCs into human adipocytes in vitro. (biomedcentral.com)
In addition to WAT and BAT, adipocytes also exist in the bone marrow, and such marrow adipose tissue (MAT) has been estimated to account for over 10% of total adipose tissue mass in lean, healthy humans ( 3 ). (frontiersin.org)
Adipose tissue-derived stem cells (ADSCs) have been characterized as having the ability to self-renew and differentiate into different connective tissue cells, including osteoblasts, adipocytes, chondrocytes and myocytes, under specific inductive stimuli ( 4 ). (spandidos-publications.com)

Conversely, brown adipose tissue (BAT) and browning of WAT represent potential therapeutic approaches, since dysfunctional white adipocyte-induced lipid overspill can be halted by BAT/browning-mediated oxidative anti-lipotoxic effects. (springer.com)
There is also evidence that the deleterious effects mediated by dysfunctional white adipocyte-induced lipid overspill can be halted by the pro-oxidative anti-lipotoxic effects mediated by brown adipose tissue (BAT) activation. (springer.com)
This study aims to investigate the molecular mechanism of Adenovirus type 36 (Ad36) in adipocyte differentiation and glucolipid metabolism. (biomedcentral.com)
Oil red O staining was used to measure differentiation into adipocyte. (biomedcentral.com)
However, the mechanism underlying the effect of Ad36 induced adipocyte differentiation and changes in glucose and lipid metabolism is unclear. (biomedcentral.com)
We speculate that Ad36 may induce adipocyte differentiation and changes of glucose and lipid metabolism by regulating PI3K/Akt/FoxO1/PPARγ signaling pathway. (biomedcentral.com)
Wortmannin, an inhibitor of PI3K, was used to further investigate the role of transcription factors FoxO1 and PPARγ and their downstream target genes in promoting adipocyte differentiation and lipid accumulation, and in regulating glucose and lipid metabolism. (biomedcentral.com)
Here, we show that murine GATA-2 and GATA-3 are specifically expressed in white adipocyte precursors and that their down-regulation sets the stage for terminal differentiation. (nih.gov)
Constitutive GATA-2 and GATA-3 expression suppressed adipocyte differentiation and trapped cells at the preadipocyte stage. (nih.gov)
Thus, GATA-2 and GATA-3 regulate adipocyte differentiation through molecular control of the preadipocyte-adipocyte transition. (nih.gov)
2009), which is inhibited during adipocyte differentiation (Dimaculangan et al. (exposed-skin-care.net)
In obese rats, the inhibition of LOX activity through -aminopropionitrile (BAPN, a particular inhibitor of LOX activity) decreases adipose cells fibrosis, partly corrects the adipocyte-size distribution design (moving it toward smaller sized sizes) and attenuates the upsurge in bodyweight and extra fat mass. (exposed-skin-care.net)

Finally, rosiglitazone upregulated uncoupling protein 1 in brown adipose tissue (BAT), but this protein was undetectable in tibiae, suggesting that MAT is unlikely to share thermogenic properties of BAT. (frontiersin.org)
Adipose tissue is typically classified into two broad subtypes, white adipose tissue (WAT) and brown adipose tissue (BAT). (frontiersin.org)
Equivalent studies in brown adipose tissue (BAT) are lacking.ObjectiveWe aimed to compare CB1 and CB2 receptor expression during WAT and BAT adipogenesis and to investi. (endocrine-abstracts.org)

Here, we summarise the mechanisms contributing to adipose tissue (AT) plasticity and function including characteristics and cellular complexity of the various adipose depots and we discuss recent insights into AT origins, identification of adipose precursors, pathophysiological regulation of adipogenesis and its relation to WAT/BAT expandability in obesity and its associated comorbidities. (springer.com)
In Situ Monitoring of Adipogenesis with Human-Adipose-Derived Stem Cells Using Surface-Enhanced Raman Spectroscopy. (ncsu.edu)
After 22 days of differentiation, the cells show visible and spectroscopic indications of completed adipogenesis yet still share spectral features common to the progenitor stem cells. (ncsu.edu)
Here we examined how ROS and FOXO regulate adipogenesis in human adipose-derived stem cells (hASC). (edu.au)
We then mimicked IDII-induced oxidative stress through a lentiviral overexpression of Nox4 and an exogenous application of hydrogen peroxide in hASC and both manipulations significantly enhanced adipogenesis without changing the adipogenic differentiation rate. (edu.au)

Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitizing hormone, during caloric restriction (CR), but whether this occurs in other contexts remains unknown. (frontiersin.org)

With the in-depth researches of MSCs, an increasing number of studies have indicated that the therapeutic effects of MSCs can be attributed not only to their differentiation capacity but also to their paracrine action [ 21 ]. (hindawi.com)
Adipose-tissue-derived MSCs (AdMSCs), in addition to being easier and safer to isolate than bone-marrow-derived MSCs, can be obtained in larger quantities. (wikipedia.org)
The differentiation, proliferation, prognosis, and safety of MSCs for in vivo therapy remain controversial. (molvis.org)

The goal of this protocol is to test the ability of progenitor cells derived from human perivascular adipose tissue to differentiate into multiple cell lineages. (jove.com)
Adipose progenitor cells vary according to their anatomical location. (jove.com)
Pre-adipose cells were found to be fibroblasts characterized by their spindle shape, long tenuous cytoplasmic extensions, and profuse endoplasmic reticulum. (rupress.org)
Aim of this study is to optimize adipogenic differentiation of adipose stem cells using two different hydrogels and varying cell densities. (tuni.fi)
In the study, adipogenic differentiation of human adipose-derived stem cells (hASCs) was tested in hydrazone crosslinked gellan gum/gelatin (1:1) hydrogel (gellan gum 40 mg/ml in αMEM and gelatin CDH 40 mg/ml in αMEM. (tuni.fi)
The cells were seeded inside the hydrogel in a 48-well-plate format at densities of 0,5, 1,0, ja 2,0 x 106 cells/ml hydrogel and cultured in adipogenic differentiation medium (AM). Differentiation of hASCs was analyzed and quantified using AdipoRed staining and WST-1 cell proliferation assay after 14 or 21 days of culturing. (tuni.fi)
2D hASC culture with 1053 cells/cm2 was used as a differentiation control. (tuni.fi)
These findings suggested that overex-pression of the Cbfa1 gene induced a remarkable and rapid differentiation of ASCs into osteogenic cells. (jarde.jp)
Expression of Pdx-1, Glut-2 and Insulin genes in EX-4 treated cells was significantly higher than the cells exposed to differentiation media without EX-4. (celljournal.org)
This report uses 40-nm colloidal gold nanoparticles to create volumes of surface-enhanced Raman scattering (SERS) within living human-adipose-derived adult stem cells enabling molecular information to be monitored. (ncsu.edu)
We exploit this method to spectroscopically observe chemical changes that occur during the adipogenic differentiation of human-adipose-derived stem cells over a period of 22 days. (ncsu.edu)
Both reactive oxygen species (ROS) and Forkhead box O (FOXO) family transcription factors are involved in the regulation of adipogenic differentiation of preadipocytes and stem cells. (edu.au)
Previous studies have shown that human adipose stem cells (hASCs) are able to differentiate towards AF phenotype when treated with suitable growth factors. (utwente.nl)
The differentiation of stem cells into chondrocytes is a possible solution to provide a large number of differentiated chondrocytes. (tmu.edu.tw)
In this study, human adipose-derived stem cells (hASCs) have been chosen as a model for further differentiation into chondrocytes. (tmu.edu.tw)
Recently, human Adipose Derived Stem Cells (hADSCs) have received attention as a potential cell source for organ regeneration, due to the ease of access as compared to bone marrow stem cells and the more controversial embryonic stem cells. (furman.edu)
Although differentiation was successful, the results were incomparable to actual uroepithelial cells. (furman.edu)
We conclude that by manipulating the composition of the culture medium it is possible to induce canine ADMSCs into insulin-producing cells, and the 2-staged protocol that was used promoted the best differentiation. (sdlifesciences.com)
Several anti-diabetic strategies including adiponectin, ezetimibe, liraglutide, taurine, adipose tissue-derived stem cells (ADSCs) and even exercise as well as natural products such GABA tea, geniposide, guava extract, vitamin D have been shown to target autophagy. (frontiersin.org)
Growing adipose-derived stem cells under serum-free conditions. (otago.ac.nz)
In the present study, the potential of using exosomes isolated from adipose‑derived stem cells (ADSCs) as a therapeutic tool for reducing chronic inflammation and promoting chondrogenesis was investigated using patient‑derived primary cells. (spandidos-publications.com)
In total, 1-10% of nucleated cells in adipose tissue are ADSCs, whereas only 0.0001-0.01% of nucleated cells in bone marrow are stem cells ( 5 ). (spandidos-publications.com)
BAPN also ameliorated the upsurge in collagen content material that was seen in adipose cells from obese pets and improved many metabolic guidelines C it ameliorated blood sugar and insulin amounts, reduced homeostasis model evaluation (HOMA) index and decreased plasma triglyceride amounts. (exposed-skin-care.net)
Furthermore, in white adipose cells from obese pets, BAPN avoided the downregulation of adiponectin and blood sugar transporter 4 (GLUT4), aswell as the upsurge in suppressor of cytokine signaling 3 (SOCS3) and dipeptidyl peptidase 4 (DPP4) amounts, triggered from the HFD. (exposed-skin-care.net)
Consequently, our data offer proof that LOX takes on a pathologically relevant part in the metabolic dysfunction induced by weight problems and emphasise the eye of book pharmacological interventions that focus on adipose cells fibrosis and LOX activity for the medical management of the disease. (exposed-skin-care.net)
A transcriptomic research revealed a rise in LOX manifestation in subcutaneous white adipose cells from obese topics, but its pathophysiological relevance continues to be unclear (Henegar et al. (exposed-skin-care.net)
2008). Consequently, the purpose of this research was to explore the part of LOX activity in adipose cells remodelling and in the metabolic disruptions associated with weight problems. (exposed-skin-care.net)
Lately, fibrosis continues to be recognised as an essential participant in adipose cells dysfunction in weight problems. (exposed-skin-care.net)
Nevertheless, its contribution to adipose cells dysfunction in weight problems is not clearly established. (exposed-skin-care.net)
Outcomes This research analyses the part of LOX in adipose cells remodelling through the use of three experimental systems: adipose cells examples from obese people that had been known for bariatric medical procedures (weight loss operation), an pet style of diet-induced weight problems and cell-based research. (exposed-skin-care.net)
The writers demonstrate that LOX may be the primary lysyl oxidase isoenzyme indicated in Rabbit polyclonal to ZFP161 human being adipose cells and that it's upregulated in examples from both obese people and rats given a high-fat diet plan. (exposed-skin-care.net)
Also, in these pets, BAPN ameliorates the disruptions in the adipose cells manifestation of adiponectin, blood sugar transporter 4 (GLUT4), buy 76584-70-8 suppressor of cytokine signaling 3 (SOCS3) and dipeptidyl peptidase 4, all protein mixed up in control of insulin level of sensitivity. (exposed-skin-care.net)
Ghasemi-Mobarakeh L, Prabhakaran MP, Tian L, Shamirzaei-Jeshvaghani E, Dehghani L, Ramakrishna S. Structural properties of scaffolds: Crucial parameters towards stem cells differentiation. (wjgnet.com)
The adipose tissue is an important reservoir of adult stem cells which have capacity of differentiating in osteoblasts with potential implication in reaching bone regeneration. (bvsalud.org)
that regulate the differentiation and activation of these cells. (cdc.gov)

Studies on the influence of porous biomaterials on cell behavior have been performed to determine the best conditions for stem cell differentiation. (tmu.edu.tw)

This is the first study to examine the differentiation behavior of hASCs on collagen–PCL sheath–core bicomponent nanofiber scaffolds developed using a co-axial electrospinning technique. (ncsu.edu)
Differentiation of hASCs was induced by using the micromass culture technique. (utwente.nl)

The 'adipose tissue expandability model' identifies the limited capacity and dysfunctionality of WAT, preventing its expansion and accommodation of surplus of energy, as key determinants for the onset and progression of obesity-associated metabolopathologies as a result of ectopic deposition of toxic lipid species in metabolic organs (i.e. muscle or liver [also known as lipotoxic insult]) [ 7 ]. (springer.com)
Adipose tissue in obesity becomes refractory to suppression of fat mobilization by insulin, and also to the normal acute stimulatory effect of insulin on activation of lipoprotein lipase (involved in fat storage). (cambridge.org)
Studies of rare disorders affecting the amount and distribution of body fat provide opportunities to define previously unidentified genes and biological pathways involved in appetite regulation, adipose tissue biology, and energy homeostasis, and to provide novel insights into the myriad of mechanisms potentially contributing to obesity and its adverse consequences. (nih.gov)
Extracellular matrix (ECM) remodelling from the adipose tissue plays a pivotal role in the pathophysiology of obesity. (exposed-skin-care.net)

Differentiating white adipose tissue from presumptive and developing fat pads of newborn and young rats was fixed in buffered osmium tetroxide, embedded in Vestopal W, and examined in an electron microscope. (rupress.org)
White adipose tissue (WAT) has key metabolic and endocrine functions and plays a role in regulating energy homeostasis and insulin sensitivity. (springer.com)
White adipose tissue (WAT) plays a key homeostatic role, not only by ensuring efficient energy storage but also by its quick mobilisation (lipids) to ensure peripheral demands. (springer.com)
The antidiabetic thiazolidinediones (TZDs) also promote MAT expansion and hyperadiponectinemia, even without increasing adiponectin expression in white adipose tissue (WAT). (frontiersin.org)
CB1 antagonism may have potential in the metabolic syndrome, with effects mediated through central orexigenic mechanisms and via peripheral action on white adipose tissue (WAT). (endocrine-abstracts.org)

Most of these paracrine secretions include soluble factors and exosomes, which regulate the repair and regeneration processes at sites of damage by affecting cell proliferation, migration, and differentiation [ 22 , 23 ]. (hindawi.com)

Scaffolds play an important role in tissue engineering as a substrate that can mimic the native extracellular matrix and the properties of scaffolds have been shown to affect the cell behavior such as the cell attachment, proliferation and differentiation. (wjgnet.com)

Also, quantitative and qualitative analysis methods for adipogenic differentiation are optimized for 3D-cell culture. (tuni.fi)
In the study, we showed that the adipogenic differentiation of hASC is dependent on the cell number. (tuni.fi)

This protocol is used to answer key questions related to the function of human adipose progenitors in the vascular microenvironment. (jove.com)
Obtain a 500 milligram piece of Human Perivascular Adipose Tissue or PVAT from the operating room as described in the text protocol. (jove.com)
Biopsy of adipose tissue identified human adenovirus 36 (Adv 36) DNA. (cdc.gov)

This work demonstrates the first report of the simultaneous co-culture and differentiation of 3D TE skeletal muscle and bone, and represents a significant step toward a full in vitro 3D musculoskeletal junction model. (sdlifesciences.com)
We have identified epigenetic modifications in pancreatic islets, skeletal muscle, adipose tissue, and the liver from individuals with type 2 diabetes compared with controls. (lu.se)

Adipose tissue serves as an important energy storage, but it also participates in several biological processes, including endocrine and paracrine regulation of energy metabolism and thermoregulation. (tuni.fi)

Perivascular adipose tissue surrounds blood vessels and regulates cardiovascular physiology. (jove.com)
High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6. (atlasgeneticsoncology.org)

In vitro data link observed UPP alterations to increased levels of oxidative stress and altered adipose biology relevant to both aging and differentiation. (elsevierpure.com)

In group AT, both at 7 and 90 post-operative days, the main healing type was the presence of dense conjunctive tissue exhibiting bundles of collagen fibers disposed in beams permeating the remaining adipose tissue with rare heterotopic bone formation associated to fibrosis and different types of tissue necrosis. (bvsalud.org)

The developmental stages traced from fibroblast to mature adipose cell show a gradual change in cell shape, an accumulation of cytoplasm and non-membrane-bounded lipid, a decrease in the endoplasmic reticulum, and a change in shape of mitochondria. (rupress.org)

We show that a population of multipotent progenitors can be derived successfully from perivascular adipose tissue from patients with cardiovascular disease. (jove.com)

The expression of Adipoq, Lpin1 and Glut4 in the adipose tissue increased. (biomedcentral.com)

Lipodystrophy, lack of adipose tissue, is also associated with insulin resistance. (cambridge.org)
Any plausible explanation for the link between excess adipose tissue and insulin resistance needs to be able to account for this observation. (cambridge.org)
Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal adipose tissue), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (msdmanuals.com)

Specifically, hydrostatic pressure (HP) has been implicated as a key regulator of AMSC differentiation, whereas the mechanisms that underlie the effects of HP on osteogenesis of AMSCs are not fully understood. (aging-us.com)

We postulate that these abnormal adipose tissue deposits were caused by Adv 36 infection. (cdc.gov)

Viral DNA was isolated from brain, lung, liver, muscle, and adipose tissue of monkeys 7 months after initial infection, long after the active virus has disappeared from blood and feces ( 3 ). (cdc.gov)

Functionalized carbon nanotube and graphene oxide embedded electrically conductive hydrogel synergistically stimulates nerve cell differentiation. (nature.com)

The results of these analyses revealed that the differentially expressed exosomal miRNAs participate in multiple biological processes, such as gene expression, synthesis of biomolecules, cell development, differentiation, and signal transduction, among others. (hindawi.com)
No transport of particulate lipid from the lumen of the capillary to, or within, the adipose cell was detected, nor could any cell organelle be demonstrated to be visibly related to lipid synthesis and/or deposition. (rupress.org)
Then, we compared the influence of pore size on cell growth and differentiation. (tmu.edu.tw)
The UPP is known to be involved in regulating the differentiation of a variety of cell types, although the potential changes in the UPP during adipose differentiation have not been fully elucidated. (elsevierpure.com)
Rarely, adipose differentiation or spindle cell growth is noted. (medscape.com)

Anatomy66

Organisms9

Diseases11

Chemicals and Drugs84

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Phenomena and Processes62

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science3

Health Care1

Mesenchymal19

Osteogenic differentiation11

Altered in aging adipose1

Chondrogenic differentiation1

Stromal Cells2

Tissues10

Adipocytes8

Adipocyte12

Brown adipos3

Adipogenesis5

Marrow adipose tissue1

MSCs3

Cells35

Stem cell differenti1

HASCs2

Obesity4

White adipos5

Exosomes1

Proliferation and differentiation1

Adipogenic differentiation2

Human3

Skeletal muscle2

Metabolism1

Regulates2

Vitro1

Fibrosis1

Accumulation1

Cardiovascular1

Glut41

Insulin resistance3

Osteogenesis1

Abnormal1

Liver1

Hydrogel1

Cell5