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  • Adipocytes
  • Adipocytes in the accumulated fat tissues, especially around waist area and visceral organs, release several cytokines which reduce the sensitivity of several cell types to insulin leading to insulin resistant and type 2 diabetes [ 4 , 5 ]. (hindawi.com)
  • benign
  • The major aims in tissue characterization are the differentiation between normal, benign and malignant (primary, metastatic) tissues, the determination of prognostic information (e.g. tumor growth rate) and the detection of early stages or precursors of tumors. (springer.com)
  • To assess the diagnostic performance of 18 F-FDG PET-CT in differentiating soft tissue sarcomas (STSs) from benign fluid collections (BFs). (jcancer.org)
  • gene expression
  • This study tests the hypothesis that precisely controlled mechanical loading can regulate gene expression, tissue differentiation and tissue architecture in the adult skeleton and that precise manipulation of the defect's local mechanical environment can initiate a limited recapitulation of joint tissue development. (biologists.org)
  • Tissue molecular architecture was quantified using polarized light and Fourier transforms, while immunological staining and in situ hybridization were used to characterize gene expression. (biologists.org)
  • These findings indicate that the local mechanical environment is an important regulator of gene expression, tissue differentiation and tissue architecture. (biologists.org)
  • The degree of ECs differentiation was determined by capillary network formation, ECs-specific gene expression, and F-actin assembly. (scientific.net)
  • cell
  • During culture under dynamic flow, the formation of intestinal villi was accompanied by characteristic changes in impedance spectra both measured experimentally and verified with simulation, and we demonstrate that changes in cell layer capacitance may serve as measures of villi differentiation. (rsc.org)
  • CuAOs and PAOs have been found at high level in the cell-wall of several species belonging to Fabaceae and Poaceae families, respectively, especially in tissues fated to undertake extensive wall loosening/stiffening events and/or in cells undergoing programmed cell death (PCD). (frontiersin.org)
  • To explore the phenomenon that corneal and conjunctival tissues subjected to desiccating stress (DS) promote Th17 differentiation by stimulating the production of Th17-inducing cytokines through a dendritic cell (DC)-mediated pathway. (arvojournals.org)
  • These findings demonstrate that DS creates an environment on the ocular surface that stimulates the production of Th17-inducing cytokines by corneal and conjunctival epithelia that promote Th17 differentiation through a dendritic cell-mediated pathway. (arvojournals.org)
  • regulate
  • Thus, not only does the mechanical environment initiate tissue formation and resorption due to exercise and disuse, for example, but it can also regulate the very type of tissue that will form during development or healing. (biologists.org)
  • MSCs
  • However, the effect of high glucose on adipogenic differentiation of human bone marrow and gestational tissue-derived MSCs is still poorly characterized. (hindawi.com)
  • We found that high glucose reduced proliferation but enhanced adipogenic differentiation of all MSCs examined. (hindawi.com)
  • The knowledge gained from this study will increase our understanding about the effect of high glucose on adipogenic differentiation of MSCs and might lead to an improvement in the diabetic treatment in the future. (hindawi.com)
  • For constructing vessels, MSCs and EPCs were seeded on fibronectin coated ePTFE graft in tissue culture condition for 2-4 weeks. (scientific.net)
  • Potential application fields for these multipotent MSCs in small animal practice are joint diseases as MSCs of both sources have shown to possess chondrogenic differentiation ability. (sigmaaldrich.com)
  • Therefore, we compared MSCs of both origins in this study in terms of their chondrogenic differentiation ability and suitability for clinical application. (sigmaaldrich.com)
  • BM-MSCs harvested from the femoral neck and ADSCs from intra-abdominal fat tissue were examined for their morphology, population doubling time (PDT) and CD90 surface antigen expression. (sigmaaldrich.com)
  • In contrast, BM-MSCs revealed a morphological superior cartilage formation by the production of a more abundant and structured hyaline matrix and higher expression of lineage specific genes under the applied standard differentiation protocol. (sigmaaldrich.com)
  • Moreover
  • Moreover, this multi-disciplinary approach can be used to customize SAPeptides for other specific tissue engineering applications. (nih.gov)
  • Moreover, the expression levels of the keratin 10, filaggrin, and involucrin that are involved in epidermal differentiation were upregulated in a stage-specific manner. (ovid.com)
  • ADSCs
  • Immunostaining of ADSCs on EO-PCL/PEG nanofibers confirmed the change in morphology of ADSCs from spindle to polygonal shape suggesting their differentiation toward an epidermal linage. (ovid.com)
  • However, further investigations are necessary in order to find out if chondrogenic differentiation can be improved in canine ADSCs using different protocols and/or supplements. (sigmaaldrich.com)
  • contrast
  • A dual-bandwidth spectroscopic metric defined as the ratio of the 10% to 90% autocorrelation bandwidths is found to change monotonically with microsphere size and gives the best contrast enhancement for scatterer size differentiation in the resulting spectroscopic image. (ntu.edu.sg)
  • experiment
  • a ) Footage of blood versus tissue experiment with the instrumented tool-tip vertically suspended and ( b ) the SVC identification experiment in blood flow. (asme.org)
  • Simulation
  • Here, we describe methods for combining impedance spectroscopy measurements with electrical simulation to reveal transepithelial barrier function and tissue structure of human intestinal epithelium cultured inside an organ-on-chip microfluidic culture device. (rsc.org)
  • therefore
  • On the other hand, spermidine and spermine are both able to enhance hypertrophy and terminal differentiation of chondrocytes and therefore appear to be inducers of endochondral ossification. (springer.com)
  • Mass
  • This overlap in imaging appearance leads to diagnostic dilemmas in two main clinical situations: at initial diagnosis of a soft-tissue mass, and in differentiation of recurrent STS from a BF on post-operative imaging. (jcancer.org)