Embryoid BodiesCell DifferentiationEmbryonic Stem CellsStem CellsEmbryo, MammalianCells, CulturedTeratomaCell LineageEndodermGene Expression Regulation, DevelopmentalCell Culture TechniquesCell LinePluripotent Stem CellsTranscription FactorsSignal TransductionTretinoinInduced Pluripotent Stem CellsCell ProliferationRNA, MessengerReverse Transcriptase Polymerase Chain ReactionHomeodomain ProteinsOctamer Transcription Factor-3Gene Expression RegulationGerm LayersMesodermSex DifferentiationGene ExpressionImmunohistochemistryCell DivisionBone Morphogenetic Protein 4Hematopoietic Stem CellsDNA-Binding ProteinsAntigens, DifferentiationBiological MarkersPhenotypeBase SequenceGene Expression ProfilingYolk SacMolecular Sequence DataHematopoiesisMice, KnockoutFlow CytometryCell AggregationTime FactorsMice, Inbred C57BLMice, TransgenicFetal ProteinsNeuronsBone Morphogenetic ProteinsLeukemia Inhibitory FactorEmbryonic DevelopmentMyocytes, CardiacCoculture TechniquesFeeder CellsIn Situ HybridizationBone Morphogenetic Protein 2Alkaline PhosphataseTotipotent Stem CellsGATA4 Transcription FactorBasic Helix-Loop-Helix Transcription FactorsTranscription, GeneticTrans-ActivatorsDNA PrimersChimeraStage-Specific Embryonic AntigensGreen Fluorescent ProteinsOsteogenesisTransfectionCryoultramicrotomyOsteoblastsPromoter Regions, GeneticModels, BiologicalTeratocarcinomaCell SeparationEctodermCarcinoma, EmbryonalPrimitive StreakSOXB1 Transcription FactorsEmbryonic and Fetal DevelopmentBlotting, WesternLamininFluorescent Antibody TechniqueGerm CellsMesenchymal Stromal CellsDown-RegulationAdipogenesisBlastocystCulture Media, Serum-FreeCell SurvivalMorphogenesisTumor Cells, CulturedRepressor ProteinsTissue EngineeringUp-RegulationOligonucleotide Array Sequence AnalysisNuclear ProteinsApoptosisFibroblastsKruppel-Like Transcription FactorsHepatocyte Nuclear Factor 3-beta