• Drosophila embryos are easily amenable to imaging because they are more transparent than the embryos of other model organisms, such as mice. (nature.com)
  • 3.In the syncitial blastoderm stage of Drosophila embryos, nuclei move to the periphery and are held in their positions just beneath the plasma membrane by the cytoskeleton. (brilliantessay.com)
  • Long germ-band insects, such as the fruit fly Drosophila melanogaster , form most of their segments simultaneously at the blastoderm stage, i.e., before gastrulation. (biomedcentral.com)
  • Drosophila embryogenesis has proven to be an extremely powerful system for developmental gene discovery and characterization. (peerj.com)
  • In this report, we used the zebrafish model to examine the role of esrra in cartilage development during vertebrate embryogenesis. (nature.com)
  • He is most well known for his descriptions of phylogenetic trees, studies of radiolarians, and illustrations of vertebrate embryos to support his biogenetic law and Darwin's work with evolution. (asu.edu)
  • This primer describes these pleiotropic roles of Hes genes in some developmental processes and aims to clarify the basic mechanism of how gene networks operate in vertebrate embryogenesis. (biologists.com)
  • In this area of study, SSPs are used as markers to determine the embryogenic potential and competency of the embryogenic system to produce a somatic embryo biochemically similar to its zygotic counterpart (Flinn et al. (wikipedia.org)
  • lilli zygotic mutant embryos exhibit a partially ventralized phenotype similar to dpp embryonic lethal mutations (Su, 2001). (sdbonline.org)
  • As embryogenesis proceeds, the control over development is gradually transferred to the zygotic genome, and embryos get rid of the old maternal transcripts and replace them with newly synthesized zygotic mRNAs. (harvard.edu)
  • In this context in vitro germination of zygotic embryo could be a promising alternative. (arccjournals.com)
  • Hence in this study the effect of culturing media, plant growth regulators and genotypes were assessed on in vitro regeneration and plantlet development of oil palm zygotic embryos. (arccjournals.com)
  • Zygotic embryos of four elite genotypes were cultured on MS, N6 and Y3 media, with or without plant growth regulators (NAA, BA& GA3-0.2mg/lt). (arccjournals.com)
  • There was no effect of culture media, plant growth regulators and genotypes on germination of zygotic embryos. (arccjournals.com)
  • In vitro germination and embryogenic competence acquisition of Euterpe edulis Martius immature zygotic embryos. (arccjournals.com)
  • In vitro culture of zygotic embryos of Butia eriospatha. (arccjournals.com)
  • Cryopreservation of zygotic embryos and kernels of oil palm (Elaeis guineensis Jacq. (arccjournals.com)
  • 2016). Mature zygotic embryo rescue improves in vitro germination and seedling production in high value oil palm (Elaeis guineensis Jacq. (arccjournals.com)
  • Such pathways include binding of the zebrafish microRNA miR-430 to hundreds of maternal mRNAs but do not explain the bulk of mRNA degradation in embryos. (harvard.edu)
  • The resulting computational models established sequence-based rules that were able to predict the kinetics of mRNA decay during early zebrafish embryogenesis. (harvard.edu)
  • Both genes are activated at the beginning of neurula stage and steady-state mRNA levels progressively increase thereafter. (rupress.org)
  • At later stages of development and parallel to increased mRNA accumulation, collagen expression becomes progressively more confined to chondrogenic regions of the tadpole. (rupress.org)
  • mRNA transcripts of Hippo signaling pathway constituents (Crb3, Mst2, Yap1 and Taz) were observed during all the stages of bovine preimplantation embryo development. (uoguelph.ca)
  • E) Expression of pqbp1 and ncam mRNA in the neural plate of early neurula embryos. (xenbase.org)
  • right panel, embryos injected dorsally with pqbp1 mRNA (2 ng) at the four-cell stage. (xenbase.org)
  • Somatic embryos are formed from plant cells that are not normally involved in the development of embryos, i.e. ordinary plant tissue. (wikipedia.org)
  • 2,4-Dichlorophenoxyacetic acid (2,4-D), 6-Benzylaminopurine (BAP) and Gibberellic acid (GA) has been used for development of indirect somatic embryos in strawberry (Fragaria ananassa) Plant regeneration via somatic embryogenesis occurs in five steps: initiation of embryogenic cultures, proliferation of embryogenic cultures, prematuration of somatic embryos, maturation of somatic embryos and plant development on nonspecific media. (wikipedia.org)
  • Plant transformations Mass propagation The development of somatic embryogenesis procedures has given rise to research on seed storage proteins (SSPs) of woody plants for tree species of commercial importance, i.e., mainly gymnosperms, including white spruce. (wikipedia.org)
  • This study contributes to the development of fundamental approaches for assessing embryogenesis on the basis of extracted quantitative criteria. (nature.com)
  • Thus, embryo development is highly dynamic. (nature.com)
  • Implantation of the human embryo leads to a number of changes in organization that are essential for gastrulation and future development 1 . (nature.com)
  • Chloroplast biogenesis and function is essential for proper plant embryo and seed development but the molecular mechanisms underlying the role of plastids during embryogenesis are poorly understood. (frontiersin.org)
  • We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)
  • The prin2.2 and csp41b-2 single mutants displayed pale phenotypes, abnormal chloroplasts with reduced transcript levels of photosynthesis genes and defects in embryo development. (frontiersin.org)
  • In silico analysis of available array data showed that a large number of genes traditionally classified as PEP dependent genes are transcribed during early embryo development from the pre-globular stage to the mature-green-stage. (frontiersin.org)
  • Taken together, our results suggest that PEP activity and consequently the switch from NEP to PEP activity, is essential during embryo development and that the PRIN2-CSP41b DNA binding protein complex possibly is important for full PEP activity during this process. (frontiersin.org)
  • In this report, we establish an in vivo role of Esrra in cartilage development during embryogenesis in zebrafish. (nature.com)
  • The role of ESRRs during animal development may also be linked to metabolic regulation by which developing embryos meet their high energy demand for growth. (nature.com)
  • Expression of esrra is colocalised with genes necessary for cartilage development in pharyngeal arches during zebrafish embryogenesis. (nature.com)
  • Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
  • Haeckel aggressively argued that the development of an embryo repeats or recapitulates the progressive stages of lower life forms and that by studying embryonic development one could thus study the evolutionary history of life on earth. (asu.edu)
  • As the development of embryology grew in importance during the late 1800s, so did the need for models to show intricate details of embryos. (asu.edu)
  • In this primer, we describe the key features of Hes factors and detail their roles in some representative processes of embryogenesis: namely, in the development of the nervous and digestive systems, two well-characterized processes, where Hes1 (and Hes3 and Hes5 in the nervous system) regulates cell proliferation and differentiation, and in the process of somite segmentation, where Hes7 functions as a biological clock. (biologists.com)
  • During seed maturation, reserve deposition and the effect of plant growth regulators and osmoticum on embryo development are active areas of research. (gc.ca)
  • The ability to manipulate these various stages of embryo development has significant potential overall tree performance. (gc.ca)
  • Cell surface molecules expressed on embryos in a stage-specific manner appeared to play key roles in regulation of cell-cell interaction and cell sorting during early development. (nih.gov)
  • Pasadena, CA, USA - Research on human embryos is vital to understanding the earliest stages of human development. (stembook.org)
  • Though these embryo-like structures have some key differences from real embryos, the technology to create them will be critical in answering open questions about human development without the need for donated embryos. (stembook.org)
  • Thus, this model system may lead to breakthroughs in the understanding of early embryonic development that are not constrained by the limited availability of human embryos. (stembook.org)
  • Additionally, this system can be used to understand how different cellular components coordinate their development at very early stages and the impact of this cellular cross-talk upon later developmental stages. (stembook.org)
  • The £1M funding will support understanding the earliest stages of development, which if it occurs incorrectly can lead to birth defects such as scoliosis and certain cancers. (dundee.ac.uk)
  • Hedda continues, "We will use stem cell derived model systems that facilitate research into the development of human embryogenesis without the use of human or animal embryos. (dundee.ac.uk)
  • We show that the conditional depletion of the m 6 A reader protein Ythdf2 in mice causes lethality at late embryonic developmental stages, with embryos characterized by compromised neural development. (biomedcentral.com)
  • In the very early stages of development, the mother controls virtually all aspects of animal embryogenesis: the genomes of early embryos are silent, and mRNAs and proteins that were deposited into the egg by the mother provide all functionality, from metabolism to cell division. (harvard.edu)
  • Four main waves of miRNA expression were recognized (with most miRNA changes occurring during the embryonic stages): the first from day 0 to day 1 of embryogenesis, the second during mid-embryogenesis (days 0-6), the third (with an acute expression peak) on day 2 of embryonic development, and the fourth during post-embryonic development. (biomedcentral.com)
  • miRNAs follow well-defined patterns of expression over hemimetabolan ontogeny, patterns that are more diverse during embryonic development than during the nymphal stages. (biomedcentral.com)
  • The results suggest that miRNAs play important roles in the developmental transitions between the embryonic stages of development (starting with maternal loading), during which they might influence the germ-band type and metamorphosis mode. (biomedcentral.com)
  • Embryogenesis was unaffected by exposure to high-CO 2 seawater up to the trochophore stage, but development at the trochophore stage was delayed when the shell began to form. (int-res.com)
  • Blastocyst formation is an important milestone in preimplantation embryo development. (uoguelph.ca)
  • Thus, the aim of present study was to characterize Hippo signaling pathway during bovine preimplantation embryo development. (uoguelph.ca)
  • In order to evaluate the localization of Hippo pathway components, embryos at timed stages of development were stained using specific antibodies and observed with laser confocal microscope. (uoguelph.ca)
  • While MST1/2 proteins were located in the cytoplasm during various stages of bovine embryonic development, TAZ and p-YAP were detected in the nucleus during morula and blastocyst stages. (uoguelph.ca)
  • The current research activity focuses at unravelling the genetic and the molecular basis of embryo development, with particular emphasis on the early stages of mammalian embryogenesis as well as on muscular, cardiovascular and neural differentiation. (cnr.it)
  • Here, we reveal essential roles for PQBP1 and a binding partner, WBP11 , in early development of Xenopus embryos. (xenbase.org)
  • Given the advantages of silicone immersion objectives, they are particularly useful in the areas of developmental biology, such as the macro and micro observation of embryos, zebrafish and other model organisms, as well as in regenerative biology for the investigation of the development and differentiation of embryonic stem and induced pluripotent stem (iPS) cells. (olympus-lifescience.com)
  • Understanding the very early stages of embryo development is of interest because this knowledge may help explain why a significant number of human pregnancies fail at this time. (cam.ac.uk)
  • The particular stem cells that will eventually make the future body, the embryonic stem cells (ESCs) cluster together inside the embryo towards one end: this stage of development is known as the blastocyst. (cam.ac.uk)
  • This is because early embryo development requires the different types of cell to coordinate closely with each other. (cam.ac.uk)
  • However, in a study published today in the journal Science , Cambridge researchers describe how, using a combination of genetically-modified mouse ESCs and TSCs, together with a 3D scaffold known as an extracellular matrix, they were able to grow a structure capable of assembling itself and whose development and architecture very closely resembled the natural embryo. (cam.ac.uk)
  • Both the embryonic and extra-embryonic cells start to talk to each other and become organised into a structure that looks like and behaves like an embryo," explains Professor Magdalena Zernicka-Goetz from the Department of Physiology, Development and Neuroscience, who led the research. (cam.ac.uk)
  • Comparing their artificial 'embryo' to a normally-developing embryo, the team was able to show that its development followed the same pattern of development. (cam.ac.uk)
  • To do so, it would likely need the third form of stem cell, which would allow the development of the yolk sac, which provides nourishment for the embryo and within which a network of blood vessel develops. (cam.ac.uk)
  • Professor Zernicka-Goetz recently developed a technique that allows blastocysts to develop in vitro beyond the implantation stage, enabling researchers to analyse for the first time key stages of human embryo development up to 13 days after fertilisation. (cam.ac.uk)
  • She believes that this latest development could help them overcome one of the main barriers to human embryo research: a shortage of embryos. (cam.ac.uk)
  • We are very optimistic that this will allow us to study key events of this critical stage of human development without actually having to work on embryos. (cam.ac.uk)
  • Our main model organism is the chick embryo, ideal for functional and translational studies on neural crest development. (lu.se)
  • Chick embryos are easily accessible, and their nervous system development is similar to that of human embryos at comparable stages. (lu.se)
  • 1) elucidating the role of neuroblastoma associated protein HIF-2a in neural crest development and its potential role in tumor onset, 2) how trunk neural crest specific genes can function as tumor suppressor genes in neuroblastoma, and 3) develop inducible tumor models using chick embryos. (lu.se)
  • During the third week of development, ectodermal cells in the caudal portion of the developing embryo proliferate and migrate medially and caudally to form the notochordal process. (medscape.com)
  • In summary, BCA affected development of Xenopus embryos only at high concentrations, while DBA did not affect Xenopus development at the concentrations tested. (cdc.gov)
  • 5-HT also has a stimulatory role in tooth germ development by inducing the formation of enamel and dental papilla to form the bell and crown stages. (bvsalud.org)
  • Expression of two nonallelic type II procollagen genes during Xenopus laevis embryogenesis is characterized by stage-specific production of alternatively spliced transcripts. (rupress.org)
  • The pattern of type II collagen expression during Xenopus laevis embryogenesis has been established after isolating specific cDNA and genomic clones. (rupress.org)
  • Type II collagen expression is therefore temporally regulated by tissue-specific transcription and splicing factors directing the synthesis of distinct molecular forms of the precursor protein in the developing Xenopus embryo. (rupress.org)
  • At the molecular level, knockdown of PQBP1 in Xenopus animal cap explants inhibits target gene induction by FGF but not by BMP, Nodal or Wnt ligands, and knockdown of either PQBP1 or WBP11 in embryos inhibits expression of fgf4 and FGF4 -responsive cdx4 genes. (xenbase.org)
  • Adverse developmental effects of two haloacetic acids, bromochloroacetic acid (BCA) and dibromoacetic acid (DBA), were determined by using the Frog Embryo Teratogenesis Assay--Xenopus (FETAX). (cdc.gov)
  • Somatic embryos are mainly produced in vitro and for laboratory purposes, using either solid or liquid nutrient media which contain plant growth regulators (PGR's). (wikipedia.org)
  • Shoots and roots are monopolar while somatic embryos are bipolar, allowing them to form a whole plant without culturing on multiple media types. (wikipedia.org)
  • Germination of the somatic embryo can only occur when it is mature enough to have functional root and shoot apices Factors and mechanisms controlling cell differentiation in somatic embryos are relatively ambiguous. (wikipedia.org)
  • Several signaling molecules known to influence or control the formation of somatic embryos have been found and include extracellular proteins, arabinogalactan proteins and lipochitooligosaccharides. (wikipedia.org)
  • Somatic embryos are an excellent experimental system which permit the examination of the various stages of embryogenesis: histodifferentiation, maturation, and maturation drying. (gc.ca)
  • Research in the area of maturation drying has focused on inducing desiccation tolerance in somatic embryos. (gc.ca)
  • Somatic embryogenesis has served as a model to understand the physiological and biochemical events that occur during plant developmental processes as well as a component to biotechnological advancement. (wikipedia.org)
  • These human complete SEMs demonstrated developmental growth dynamics that resemble key hallmarks of post-implantation stage embryogenesis up to 13-14 days after fertilization (Carnegie stage 6a). (nature.com)
  • and (3) evidence of developmental dynamism relating to ability to progress, in a structurally organized manner, through morphologically characterized developmental milestones of the early post-implantation human embryo following initial aggregate formation 3 . (nature.com)
  • The length of each stage and the timing of each developmental transition are determined by complex interactions between genetic and environmental factors. (elifesciences.org)
  • In contrast, it does help elucidate the associations between developmental stages and the genetic and environmental factors affecting them. (elifesciences.org)
  • We sequenced small RNA libraries representing 11 developmental stages of B. germanica ontogeny (with especial emphasis on embryogenesis) and the changes in miRNA expression were examined. (biomedcentral.com)
  • Effect of culture media, plant growth regulators and genotypes on growth and developmental stages of oil palm (Elaeis guineensis Jacq. (arccjournals.com)
  • However, the timing and localisation of molecular markers differ across species, with rat embryos more closely recapitulating human and cow developmental dynamics, compared with the mouse. (bvsalud.org)
  • In the female embryo, due to the absence of a Y chromosome and lack of exposure to testosterone from functional testicular tissue, the normal developmental sequence of events results in fusion and canalization of the paramesonephric (Mullerian) ducts in the midline pelvis to form the female pelvic organs. (medscape.com)
  • Changes of GSL expression profile were observed during mammalian embryogenesis. (nih.gov)
  • Full autonomy is the ability to accomplish normal embryogenesis outside the maternal organism. (springer.com)
  • This is one of the critical stages of embryogenesis, when an immature embryo becomes independent of some physiological factors, in particular, hormones (mainly auxins, cytokinins, and ABA) of a maternal organism. (springer.com)
  • 2.While studying formation of the dorso-ventral axis in the fly embryo, you learnt that several maternal effect genes, when mutated, cause a dorsalized phenotype. (brilliantessay.com)
  • Embryos lacking maternal lilli expression show specific defects in the establishment of a functional cytoskeleton during cellularization, and exhibit a pair-rule segmentation phenotype. (sdbonline.org)
  • This massive degradation of maternal mRNAs is a key regulatory event in early embryos, but it is poorly understood how this process is regulated. (harvard.edu)
  • Embryonic defects are much more extreme in germline clones, where the majority of mutant embryos die during embryogenesis and do not form cuticle, implying a strong chem maternal contribution. (peerj.com)
  • Understanding given to choosing the therapy that will best safeguard the physiology of pregnancy, the factors that influence the maternal health and the well-being of the embryo or fetus. (cdc.gov)
  • Mouse naive embryonic stem cells have recently been shown to give rise to embryonic and extra-embryonic stem cells capable of self-assembling into post-gastrulation structured stem-cell-based embryo models with spatially organized morphogenesis (called SEMs) 3 . (nature.com)
  • lilli functions as a maternally provided pair-rule gene that is essential for proper cellularization, gastrulation and segmentation during embryogenesis. (sdbonline.org)
  • In contrast, short germ-band species start gastrulation with just a few segments, and then progressively add new ones from an undifferentiated growth zone situated at the posterior end of the embryo [ 1 ]. (biomedcentral.com)
  • While these populations have been extensively studied in non-human model systems, their identification and study in vivo human tissues have been limited due to the ethical and technical limitations of accessing gastrulation stage human embryos. (stanford.edu)
  • At later times and coincident with the appearance of chondrogenic tissues in the developing embryo, expression of the procollagen genes is characterized by the production of an additional, alternatively spliced transcript. (rupress.org)
  • Expression of target genes involved in osteogenesis and bone P homeostasis in vertebrates were then analysed and a ploidy effect of osteogenic genes alp, igf1r and opn as well as a dietary effect on P homeostasis gene fgf23 was apparent in the parr stages but not smolt. (phddata.org)
  • For example, since most diseases are multigenic in origin, we are generating genome-wide genetic interaction maps for genes with essential roles in the early embryo that will help us understand how these interactions affect embryogenesis. (nyu.edu)
  • Full Study: Berna Sozen, Victoria Jorgensen, Bailey A. T. Weatherbee, Sisi Chen, Meng Zhu & Magdalena Zernicka-Goetz (2021) " Reconstructing aspects of human embryogenesis with pluripotent stem cells , Nature Communications , published online 7 Sep 2021 (DOI: 10.1038/s41467-021-25853-4). (stembook.org)
  • The space inside the embryo spreads, and the morula becomes a blastocyst. (nature.com)
  • During murine preimplantation embryogenesis, the Hippo signaling pathway is known to play a significant role in lineage segregation and henceforth the formation of blastocyst. (uoguelph.ca)
  • Embryos with strongly disrupted apico-basal polarity do not develop, and result in lethal mutant phenotypes where only small pieces of cuticle are synthesized. (peerj.com)
  • A fraction of these mutant embryos have lethal head involution or dorsal open phenotypes, and have an extended phenocritical period. (peerj.com)
  • H) Phenotypes of tailbud stage embryos dorsally targeted with control (CT) or the indicated amount of pqbp1 MO1. (xenbase.org)
  • To complement the in vivo system of chick embryos, we also employ human cell cultures, chick neural crest derived in vitro crestospheres and in vivo mice models. (lu.se)
  • At the end of the third week, a midline neural groove develops along the dorsal surface of the embryo. (medscape.com)
  • Immature embryo: A useful tool for oil palm (Elaeis guineensis Jacq. (arccjournals.com)
  • Plant growth regulators in the tissue culture medium can be manipulated to induce callus formation and subsequently changed to induce embryos to form the callus. (wikipedia.org)
  • The ratio of different plant growth regulators required to induce callus or embryo formation varies with the type of plant. (wikipedia.org)
  • We examined the changes in miRNA expression over the ontogeny of the German cockroach Blattella germanica , using 11 small RNA libraries prepared and sequenced in our laboratory, representing developmentally important stages. (biomedcentral.com)
  • Compared to controls, in chem mutants in embryonic lateral epithelia Crumbs expression is mislocalized and reduced, Coracle is increased and mislocalized basally at embryonic stages 13-14, then reduced at stage 16. (peerj.com)
  • These results suggest that oxidative stress factor might not be an eminent factor affecting the expression of Hippo signaling pathway constituents in early bovine embryogenesis. (uoguelph.ca)
  • C) Expression of pqbp1 and chordin in gastrulae, stage 11.5. (xenbase.org)
  • Like the original allele, a fraction of mutant embryos die with cuticular defects, notably head involution and dorsal closure defects. (peerj.com)
  • For example, in the developing nervous system of mouse embryos,progenitor cells proliferate and sequentially give rise to different types of cells by changing their differentiation competency. (biologists.com)
  • Somatic embryogenesis has been described to occur in two ways: directly or indirectly. (wikipedia.org)
  • Embryogenesis would never occur. (bioedge.org)
  • Abnormalities in this process may occur during embryogenesis, which can result in the range of known paramesonephric anomalies. (medscape.com)
  • Autonomy is a special structural and functional state of an embryo, reflecting its ability for self-regulation and independence from the adjacent tissues. (springer.com)
  • Embryo-like models with spatially organized morphogenesis and structure of all defining embryonic and extra-embryonic tissues of the post-implantation human conceptus (that is, the embryonic disc, the bilaminar disc, the yolk sac, the chorionic sac and the surrounding trophoblast layer) remain lacking 1 , 2 . (nature.com)
  • The structures are made from a type of pluripotent stem cell that gives rise to distinct types of cells that then self-assemble into a structure with morphology clearly reminiscent of that of an embryo, which has distinct embryonic and extra-embryonic tissues. (stembook.org)
  • Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
  • To analyse the time-series 3D microscopic images of developing embryos with fluorescently labelled nuclei, these studies used image segmentation. (nature.com)
  • Temperature and lighting can also affect the maturation of the somatic embryo. (wikipedia.org)
  • Although it is possible to culture structures derived from human blastocysts ex vivo, these cultures do not recapitulate the events and structural organization of the in vivo embryos 6 ( Supplementary Information ). (nature.com)
  • Combining in vivo and in vitro assays, we show that the proliferation and differentiation capabilities of NSPCs decrease significantly in Ythdf2 −/− embryos. (biomedcentral.com)
  • Such human fully integrated and complete SEMs recapitulate the organization of nearly all known lineages and compartments of post-implantation human embryos, including the epiblast, the hypoblast, the extra-embryonic mesoderm and the trophoblast layer surrounding the latter compartments. (nature.com)
  • Localization of TAZ and p-YAP proteins were distinct in the bovine model as compared to the mouse model, suggesting the Hippo signaling pathway to be regulated differently in early bovine embryos. (uoguelph.ca)
  • In the US, where a portion of the population is opposed to destruction of human embryos to obtain stem cells, what avenues are open to scientists for obtaining pluripotent cells that do not offend the moral sensibilities of a significant number of citizens? (asu.edu)
  • The fourth, and most novel idea, is to develop stem cells from genetically altered cells which could never develop into an embryo. (bioedge.org)
  • According to one of its champions, Professor Robert George, of Princeton University, "we would reasonably expect to obtain precisely the type of stem cells desired by advocates of embryonic stem-cell research, without ever creating or killing embryos. (bioedge.org)
  • Now, Caltech researchers have created embryo-like structures out of human stem cells. (stembook.org)
  • In contrast to natural embryos that are formed by a combination of sperm and egg, these structures are formed by combining so-called pluripotent stem cells, which have the ability to develop into specialized types of cells. (stembook.org)
  • The pluripotent stem cells were initially isolated from a real human embryo by other researchers and have since been maintained in a laboratory environment. (stembook.org)
  • The paper is titled "Reconstructing aspects of human embryogenesis with pluripotent stem cells. (stembook.org)
  • Human induced pluripotent stem cells (hiPSCs) present an exciting alternative for modeling early human embryogenesis due to their well-established ability to differentiate into all embryonic germ layers. (stanford.edu)
  • Scientists at the University of Cambridge have managed to create a structure resembling a mouse embryo in culture, using two types of stem cells - the body's 'master cells' - and a 3D scaffold on which they can grow. (cam.ac.uk)
  • Thus, the csp41b-2prin2.2 double mutant is embryo lethal. (frontiersin.org)
  • Another is to extract them from two-day-old embryos using a non-lethal biopsy technique. (bioedge.org)
  • Mussel embryos were incubated for 144 h (6 d) in control and high-CO 2 seawater to compare embryogenesis, larval growth and morphology with ordinary light, polarized light, and scanning electron microscopy. (int-res.com)
  • We found that multivalent Le x caused decompaction of mouse embryos, indicating a functional role of Le x epitope in the compaction process. (nih.gov)
  • The other class of lilli GLC embryos fail to secrete cuticle properly. (sdbonline.org)
  • Chloroplast function is required throughout the life cycle of the plant and compromised activity can result in embryo lethality. (frontiersin.org)
  • We have shown that the establishment of cell polarity via aPKC is a conserved event in the initiation of the trophectoderm (TE) placental programme in mouse, cow and human embryos. (bvsalud.org)
  • Chinese scientists have successfully created chimeric embryos containing a combination of human and pig cells. (bioedge.org)
  • My 400-page doctoral dissertation was titled, A Philosophical and Scientific Analysis of the Nature of the Early Human Embryo (Georgetown University 1991). (lifeissues.net)
  • In contexts with limited single-cell samples, such as the early human embryo inference of transcription factor-gene regulatory network (GRN) interactions is especially difficult. (bvsalud.org)
  • Here, we assessed application of different linear or non-linear GRN predictions to single-cell simulated and human embryo transcriptome datasets. (bvsalud.org)
  • MICA predicted co-localisation of the AP-1 transcription factor subunit proto-oncogene JUND and the TFAP2C transcription factor AP-2γ in early human embryos. (bvsalud.org)
  • However, the mechanisms transducing cell polarity into cell fate in cow and human embryos are unknown. (bvsalud.org)
  • Somatic embryogenesis is an artificial process in which a plant or embryo is derived from a single somatic cell. (wikipedia.org)
  • Their application led to the successful design of artificial mRNAs with predetermined decay dynamics in early embryos: mutating or introducing specific sequences generated mRNAs with pre-determined decay profiles. (harvard.edu)
  • While this artificial embryo closely resembles the real thing, it is unlikely that it would develop further into a healthy foetus, say the researchers. (cam.ac.uk)
  • Embryogenesis involves orchestrated processes of cell proliferation and differentiation. (biologists.com)
  • We showed that the extracted criteria could be used to evaluate the differences between individual embryos. (nature.com)
  • Prospects of solving basic problems of autonomy of plants embryogenesis and and its biotechnological application autonomy are discussed. (springer.com)
  • This stage persists for a certain period, during which the animal grows and develops into the adult stage in which it reproduces, senesces, and dies. (elifesciences.org)
  • Embryogenesis depends on the timely proliferation of progenitor cells and their subsequent differentiation into multiple cell types. (biologists.com)
  • To acquire quantitative criteria of embryogenesis from time-series 3D microscopic images, image processing algorithms such as segmentation have been applied. (nature.com)
  • The project will investigate a specific process in the developing embryo called segmentation. (dundee.ac.uk)
  • We showed that QCANet can be applied not only to developing mouse embryos but also to developing embryos of two other model species. (nature.com)
  • Using QCANet, we were able to extract several quantitative criteria of embryogenesis from 11 early mouse embryos. (nature.com)
  • The consistent ultrasound image obtained with the UBM can be used to visualize and guide injection into target organs [ 9 , 10 ], including mouse embryo, to aid in targeted delivery of drugs and viral particles [ 7 , 11 ]. (hindawi.com)
  • Many mAbs showing stage-specific reactivity with mouse embryos were shown to recognize carbohydrate epitopes. (nih.gov)