Dietary nitrate. Medical search. Frequent questions

At this point, "the only way to get inorganic nitrate is in the diet - specifically by consuming beetroot juice or green leafy vegetables such as spinach and rocket. (medscape.com)
However, Jones noted that it is possible to buy beetroot shots, which contain 7 mmol of potassium nitrate in each shot, from health food shops and websites, and two such shots per day for 5 days would give a similar dose as that used in this study, starting the day before angiography. (medscape.com)
To increase performance-enhancing effects (as based upon studies using predominantly males), studies should employ a 5-9.9 mmol dose of nitrate, using beetroot juice as a vehicle, ingested ≥150 min prior exercise lasting 120-600 s (e.g.: 4-km cycling time-trial, 1500 m and 3000 m running time-trial and 2000 m rowing) and avoid antibacterial mouthwash. (acsm.org)
A sub‐sample of participants in our double‐blind, randomised, factorial‐design intervention (VaSera) trial of active beetroot juice as a nitrate source (≤11.2 mmol) or placebo (nitrate‐depleted) beetroot juice, and either ≤50 mg spironolactone or ≤16 mg doxazosin (control), had trans‐thoracic cardiac ultrasounds at baseline (n=105), 3 and 6 months (n=87) of intervention. (kcl.ac.uk)
In a double-blind, cross-over study, sixteen subjects ingested either nitrate-rich beetroot juice or a placebo and completed a continuous cycle exercise test involving 20min stages at 50% and 70% V˙O2peak and a final stage at 90% V˙O2peak until volitional exhaustion. (shu.ac.uk)
A study published by researchers at the Westmead Institute for Medical Research in Australia showed that vegetable dietary nitrates found in leafy greens and beetroot may be able to protect against age related macular degeneration of the eye. (vanduyncenter.com)
The study found that dietary nitrate supplementation (i.e, one beetroot shot or 6.4 mmol of NO3−) had a small beneficial effect on muscular endurance, power output, and velocity during back squats and bench press exercises. (evidencebasedmuscle.com)
Beetroot, a natural source of inorganic nitrate, is emerging as a potential performance-enhancing supplement in this arena. (evidencebasedmuscle.com)
Nitrates are naturally occurring compounds in various foods, including green leafy vegetables like spinach and beetroot juice. (evidencebasedmuscle.com)
This article delves deep into the science behind beetroot and its dietary nitrate supplementation benefits for resistance exercise, considering the evidence base from previous studies. (evidencebasedmuscle.com)
Simply put, dietary nitrates are compounds predominantly found in certain vegetables, with beetroot being a prime example. (evidencebasedmuscle.com)
Jones, 2014) Apart from beetroot, other supplements like spinach and arugula are also nitrate-rich. (evidencebasedmuscle.com)
Dietary nitrates are naturally occurring compounds in certain foods like leafy vegetables and beetroot. (evidencebasedmuscle.com)
Dietary nitrates, primarily found in beetroot and other root vegetables, undergo a conversion in the body to produce nitric oxide. (evidencebasedmuscle.com)
One study found that dietary nitrate supplementation, particularly beetroot juice, can improve exercise tolerance at low and high intensities. (evidencebasedmuscle.com)
A recent study evaluated the effect of daily dietary nitrate from beetroot juice on individuals with uncontrolled high blood pressure. (medicalnewsbulletin.com)
In part B, participants will be randomised to receive 3 days of either nitrate -containing beetroot juice (intervention) or nitrate -deplete beetroot juice (placebo). (bvsalud.org)
We showed that a moderate dose of dietary nitrate in the form of beetroot juice (BRJ, 0.11 mmol/kg) can improve macrovascular function and maximal walking distance in patients with PAD. (artinis.com)
Led by Professor Amrita Ahluwalia of the William Harvey Research Institute at Barts and The London School of Medicine, and Professor Ben Benjamin of Peninsula Medical School, the research reveals that it is the ingestion of dietary nitrate contained within beetroot juice -- and similarly in green, leafy vegetables -- which results ultimately in decreased blood pressure. (sciencedaily.com)
Professor Ahluwalia said: "Our research suggests that drinking beetroot juice, or consuming other nitrate-rich vegetables, might be a simple way to maintain a healthy cardiovascular system, and might also be an additional approach that one could take in the modern day battle against rising blood pressure. (sciencedaily.com)
The study behind this claim set out to test the theory that beetroot juice, a rich source of nitrates, can increase muscle stamina. (mynewsdesk.com)
It found that seven volunteers who drank half a litre of beetroot juice each day for a week doubled the amount of nitrate in their blood. (mynewsdesk.com)
Whether or not beetroot juice can be used as a natural nitrate supplement, and whether it is of benefit to athletes needs further testing. (mynewsdesk.com)
The beetroot juice contained 5.1mmol of nitrate (NO3), while the control drink had negligible nitrate content. (mynewsdesk.com)
On the last three days of the test periods (days four to six) the beetroot juice groups had a significant increase in plasma nitrite (a result of the breakdown of nitrate by the body). (mynewsdesk.com)
Beetroot is a rich dietary source of nitrates, which are converted in the body to nitrites. (askmen.com)

AMSTERDAM, Netherlands - A simple, low-cost 5-day course of dietary inorganic nitrate has shown apparent overwhelming benefit in preventing contrast-induced nephropathy (CIN) and reducing subsequent renal and cardiovascular outcomes. (medscape.com)
We feel that dietary inorganic nitrate shows huge promise in this study, and these findings could have important implications in reducing this serious complication of coronary angiography," Jones concluded. (medscape.com)
Whether replenishment of NO deficiency with dietary inorganic nitrate would offer a novel approach to reverse age-related cardiovascular alterations was not known. (nih.gov)
Dietary inorganic nitrate reverses age-related LV diastolic dysfunction and improves vascular functions. (nih.gov)
Inorganic nitrate is considered by the International Olympic Committee as one of only five dietary supplements with sufficient evidence to improve exercise performance in specific scenarios. (acsm.org)
Dietary inorganic nitrate supplementation causes physiological effects which may enhance exercise tolerance. (shu.ac.uk)
We have previously demonstrated important sex differences in the inflammatory response and its impact on endothelial function and separately that the ingestion of inorganic nitrate can protect the endothelium against this dysfunction. (bvsalud.org)
In this study, we will investigate whether sex or a dietary inorganic nitrate intervention modulates endothelial function and inflammatory responses after the COVID-19 vaccine . (bvsalud.org)
Part B will investigate the effects of sex and dietary inorganic nitrate on vascular and inflammatory responses to the COVID-19 vaccine . (bvsalud.org)
In humans, inorganic nitrate decreases blood pressure via NO generation. (sciencewatch.com)

Following pre-treatment assessment, participants will be randomized to take either 7-day dietary nitrate supplementation (sodium nitrate in capsules, 10 mg/kg/day) or 7-day placebo. (longdom.org)
Sodium nitrate (NaNO3) supplementation has been shown to protect against the development of hypertension-mediated heart failure, reverse age-related diastolic dysfunction and improve in vitro cardiac contractility. (uoguelph.ca)
At the sixth meeting, an ADI of 0-5 mg/kg bw, expressed as sodium nitrate, was allocated. (inchem.org)
This ADI was based on a NOEL for sodium nitrate of 500 mg/kg bw/day derived from a long-term toxicity study in rats and a short-term toxicity study in dogs together with a safety factor of 100. (inchem.org)
BACKGROUND: The epidemiological evidence regarding the carcinogenicity of nitrate and sodium in drinking water is limited, partly because measuring the exposure at the individual level is complex. (cdc.gov)
The present study investigates the factors associated with urinary nitrate and sodium in a high-risk area for esophageal and gastric cancers. (cdc.gov)
METHODS: For this cross-sectional study, we used data and samples collected in 2004-2008 during the enrollment phase of the Golestan Cohort Study from a random sample of 349 participants (300 individuals from 24 rural villages and 49 from the city of Gonbad), stratified by average water nitrate in their district, the source of drinking water, and the usual dietary intake of nitrate and sodium. (cdc.gov)
Nitrate, sodium, and creatinine were measured in a spot urine sample collected at the time of interview. (cdc.gov)
We used the provincial cancer registry data to calculate the cumulative incidence rates of esophageal and gastric cancers for each location through June 1, 2020, and used weighted partial Pearson correlation to compare the incidence rates with median urinary nitrate and sodium in each village or the city. (cdc.gov)
The geometric mean of the creatinine-corrected urinary nitrate concentration was 68.3mg/g cr (95%CI: 64.6,72.3), and the corresponding geometric mean for urinary sodium was 150.0 mmoL/g cr (95%CI: 139.6161.1). (cdc.gov)
The associations between nitrate and sodium excretion with esophageal cancer incidence warrant future investigation. (cdc.gov)

Nitrate‐containing juice (n=40) decreased left ventricular (LV) end diastolic volume: ‐6.3 mL (95% confidence intervals (CI) ‐11.1,‐1.6), and end systolic volume: ‐3.2 mL (‐5.9,‐0.5), and increased end diastolic mass/volume ratio: +0.04 (0.00,0.07), relative to placebo juice (n=47). (kcl.ac.uk)
Inorganic nitrates found in beet juice are converted to nitric oxide, a vasodilator. (positivechoices.com)
In a randomized, double-blind trial, researchers fed subjects 250 mL beet juice or beet juice with the nitrates removed (placebo) daily for 4 weeks. (positivechoices.com)
Researchers showed that the decrease in blood pressure was due to the chemical formation of nitrite from the dietary nitrate in the juice. (sciencedaily.com)
The nitrate in the juice is converted in saliva, by bacteria on the tongue, into nitrite. (sciencedaily.com)

In the body, nitric oxide is synthesized through the consumption of dietary nitrate, which can be found in many foods such as spinach, beets, arugula and even dark chocolate or raw cacao. (medicalnewsbulletin.com)
Beets contains compounds such as nitrates, betaine and pigments called betalains, which have several health benefits. (vitacost.com)
Beets and, to a lesser extent, spinach and carrots, increase blood flow because of their nitrate content. (todaysdietitian.com)
Beets supply naturally occurring, nonsynthetic nitrates that are converted to nitric oxide, which increases vasodilation. (todaysdietitian.com)
Unlike regular beet powder, extracts are designed to standardize the quantity of a particular nutrient in beets (e.g. dietary nitrates). (righthealth.com)
Dietary nitrates in beets are a key factor driving interest in beet-based supplements. (righthealth.com)
Nitrate-rich vegetables like beets boost nitric oxide production in the body. (righthealth.com)

2004. Dietary nitrites and nitrates, nitrosatable drugs, and neural tube defects. (cdc.gov)
The contents of harmful nitrites and nitrates in calculation on dry mass were significantly lower as a result of cooking, by 67% and 78%, respectively. (nih.gov)

In the NITRATE-CIN Study, non-ST segment elevation myocardial infarction acute coronary syndrome (ACS) patients at risk of renal injury from coronary angiography who received dietary inorganic nitrates had a 70% reduction in CIN compared with those given placebo. (medscape.com)
Use a placebo-controlled, crossover, double-blind, and randomized study designs, due to the short duration of nitrate supplementation and its short washout period. (acsm.org)
A recent randomized, double-blind, placebo-controlled, cross-over trial conducted by researchers in the Republic of Ireland and the United Kingdom aimed to assess more intensively the effect of dietary nitrate compared with placebo in individuals presenting with or suspected to have uncontrolled high blood pressure. (medicalnewsbulletin.com)
A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study. (bvsalud.org)

Dietary nitrate supplementation has been shown to be of significant benefit in healthy individuals. (dspace-express.com)

By incorporating nitrate-rich foods or food-based supplements into their diet, individuals can reap the benefits of increased endurance, improved circulation, and optimized metabolic function. (evidencebasedmuscle.com)
Including dietary nitrates in your diet, either through whole foods or supplements, can benefit overall health and fitness. (evidencebasedmuscle.com)
Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition programme. (bmj.com)
Supplements claiming to directly or indirectly enhance performance are typically the largest group of products marketed to athletes, but only a few (including caffeine, creatine, specific buffering agents and nitrate) have good evidence of benefits. (bmj.com)
A 2018 study found that blood pressure levels were lower after taking nitrate supplements. (medicalnewstoday.com)
None of the subjects were smokers or used dietary supplements. (mynewsdesk.com)
Supplements derived from the vegetable have exploded in popularity in recent years as science unravels the numerous benefits of dietary nitrates. (righthealth.com)
Nevertheless, convenience, taste, and standardization of nitrate content are a few of the factors that drive interest in supplements. (righthealth.com)
Although any pure beet powder will contain nitrates, some rival supplements specifically standardize levels to maintain a consistent dosage per serving. (righthealth.com)
Vegetarian diets can include a combination of traditional foods, dietary supplements and/or fortified foods containing botanically sourced ingredients. (naturalproductsinsider.com)

Designated discussant of the NITRATE-CIN trial at the ESC Hotline session, Roxanna Mehran, MD, Icahn School of Medicine at Mount Sinai, New York City, said the study was well designed, and the "interesting and plausible" hypothesis to raise nitric oxide levels by dietary nitrates "makes sense. (medscape.com)

However, few studies have examined if co-ingestion of nitrate with antioxidants can further elevate nitric oxide bioavailability. (wku.edu)
Concurrent nitrate and AA supplementation did not elicit additional increases to nitric oxide compared to nitrate ingestion alone. (wku.edu)

Nitrate supplementation has consistently been shown to benefit exercise performance due to its capacity to increase nitric oxide (NO), a signaling molecule that plays an important role in skeletal muscle function during exercise . (acsm.org)
Once ingested, nitrate is converted to nitrite via anaerobic bacteria in the oral cavity and nitrite is converted to NO especially under conditions of low oxygen availability and low pH, such as those that may be found in skeletal muscle during exercise . (acsm.org)
While the mechanism(s) remain unclear, in skeletal muscle, the consumption of nitrate has been shown to increase mitochondrial coupling efficiency. (uoguelph.ca)
Therefore, we investigated the impacts of this dose of dietary nitrate on skeletal muscle microvascular function and autonomic nervous system function and further related these measurements to 6-min walking distance, pain-free walking distance, and exercise recovery in patients with PAD. (artinis.com)

To examine the effects of ingesting dietary nitrate and ascorbic acid independently and concurrently on markers of nitric oxide bioavailability and oral microbiota species. (wku.edu)

Accordingly, all studies to date that have demonstrated a lack of a performance-enhancing effect of nitrate in women possess at least one of these characteristics that may potentially compromise benefits from nitrate supplementation. (acsm.org)
The researchers used concentrations and volumes of chemicals designed to maximise the effect of nitrate on muscles. (mynewsdesk.com)

Mechanistically, improved cardiovascular functions were associated with an accelerated cardiomyocyte calcium handling and augmented NO/cyclic guanosine monophosphate/protein kinase G signalling, while enhanced nitrate reduction was related to age-related differences in the oral microbiome. (nih.gov)
The enterosalivary nitrate‐nitrite‐nitric oxide pathway is an alternative pathway of nitric oxide generation, potentially linking the oral microbiome to insulin resistance and blood pressure (BP). (ahajournals.org)
Moreover, our understanding on how the oral microbiome responds to nitrate supplementation is limited, especially in women. (wku.edu)

Further research is required to understand the impact of supplementation regimen and population on the physiological effects of dietary nitrate. (wku.edu)

Despite this, improved exercise performance with nitrate intake is not a universal finding among studies . (acsm.org)
Dietary fiber intake and risk of incident disabling dementia: the circulatory risk in communities study. (cabi.org)
Objectives: It has been hypothesized that dietary fiber intake has a beneficial impact on prevention of dementia , but the epidemiological evidence is scant. (cabi.org)
We sought to examine whether dietary fiber intake is inversely associated with risk of dementia requiring care under the national insurance. (cabi.org)
The association between dietary iron intake and incidence of dementia in adults aged 60 years or over in the UK Biobank. (cabi.org)
Background Several studies have investigated the association between dietary iron intake and cognitive impairment, but little is known about the relationship between iron intake and dementia incidence. (cabi.org)
Studies have shown dietary intake of selenium can improve immune response, especially to viral agents. (medicalnewstoday.com)
Design Prospective cohort study with dietary intake assessed every four years using food frequency questionnaires. (bmj.com)
n=92 482) with valid dietary intake measurement and no cancer diagnosis at baseline. (bmj.com)
Dietary fiber intake should be roughly 14 grams per 1000 calories consumed, and should be largely soluble fiber (eg. (annecollins.com)
After adjusting for confounders, urinary nitrate was associated with being a woman, drinking groundwater, and living in high-elevation locations, but not with estimated dietary intake. (cdc.gov)

These will include: beat-to-beat BPV, cerebrovascular CO 2 reactivity and cerebral autoregulation (indices of cerebrovascular health), brachial artery diameter, central and peripheral blood pressures, vascular risk factors (i.e. resting blood pressure), and plasma nitrate/nitrite concentration. (longdom.org)
The human body processes these nitrates, leading to plasma nitrite concentration changes, which can influence exercise capacity and metabolic control. (evidencebasedmuscle.com)

This study aims to evaluate whether sex or dietary influences endothelial function and inflammatory responses in healthy volunteers after receiving the COVID-19 vaccine . (bvsalud.org)
Researchers discussed the role of vitamin C and dietary nitrate in endothelial function (EF). (news-medical.net)
Dietary intervention studies with flavanol and procyanidin-containing foods support this notion, as the consumption of these foods improves arterial endothelial function while lowering blood pressure and arterial stiffness in healthy subjects ( 8 - 10 ). (frontiersin.org)

Cocoa is one of the richest dietary sources of polyphenols, which are plant-derived antioxidants that provide big time health benefits. (guenergy.com)

Dietary fiber is an important factor in weight management and works as a "bulking agent" in the digestive system. (medicalnewstoday.com)
With respect to intestinal cancer especially, but perhaps to the other diet-related cancers as well, the questions of dietary fiber, of micronutrients such as vitamins A and E, or of minerals such as selenium require consideration and further research. (cdc.gov)

Nitrate in drinking water and the incidence of gastric, esophageal, and brain cancer in Yorkshire, England. (cdc.gov)
Nitrate and nitrite are found in our diet and, for over 50 years, they have been linked to diseases in humans, most notably gastric cancer. (sciencewatch.com)
CONCLUSION: In a rural population at high risk for esophageal and gastric cancers, nitrate excretion was associated with living at a higher elevation and using groundwater for drinking. (cdc.gov)

2011. Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension. (cdc.gov)

This study will lay the foundation for clinical trials to assess the therapeutic potential of dietary nitrate supplementation as a secondary strategy for stroke prevention in high-risk patients. (longdom.org)
Therapeutic uses of inorganic nitrite and nitrate: from the past to the future. (cdc.gov)
In addition, it will be of great interest to explore the therapeutic opportunities for nitrate and nitrite in diseases such as hypertension, atherosclerosis, and ischemia-reperfusion injury. (sciencewatch.com)
Dietary modifications may also support therapeutic measures 1 . (bvsalud.org)

There is a clear need for well-designed studies to determine whether women can benefit or not from this dietary supplement. (acsm.org)
Ionic Manganese is a concentrated liquid dietary supplement that provides manganese in an ionic form - the form most widely recognized by the body. (vitacost.com)
Postdiagnosis dietary factors, supplement use and breast cancer prognosis: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis. (who.int)

The nitrate group also showed an impressive reduction in periprocedural myocardial infarction (MI) and improved renal function at 3 months, as well as a halving of major adverse cardiovascular events and major adverse kidney events at 1 year. (medscape.com)
This conversion occurs through various pathways, including the reduction of nitrate to nitrite by bacteria in the oral cavity and the subsequent transformation of nitrite to nitric oxide through acidic conditions in the stomach. (evidencebasedmuscle.com)
However, it was aware that nitrite is formed in the human body by reduction of nitrate and that N-nitroso compounds can also be formed from nitrite and N-nitrosatable compounds under certain conditions. (inchem.org)
In addition to the saliva, secretion of nitrate occurs at other sites in the GI tract leading to reduction by the gut flora. (inchem.org)
However, it has now become clear that various pathways exist for the reduction of nitrate and nitrite back to bioactive NO again. (sciencewatch.com)

However, conflicting evidence has been reported, with some studies showing an inverse association between dietary nitrate and blood pressure regulation. (medicalnewsbulletin.com)
and 3) assess the association between dietary and urinary iodine measures, and iodine utilization-related compounds, such as perchlorate, nitrate, thiocyanate, and selenium. (cdc.gov)

Cardiac manganese-enhanced magnetic resonance imaging was performed to study the effects of dietary nitrate on myocyte calcium handling. (nih.gov)
To explore whether long‐term intervention with dietary nitrate ((NO3‐), a potential tolerance‐free source of beneficial vasoactive nitric oxide) and spironolactone (to oppose aldosterone's potential deleterious cardiovascular effects) improve cardiac structure/function, independent of blood pressure (BP), in patients with/at risk of type 2 diabetes (a population at risk of heart failure). (kcl.ac.uk)
6 months' dietary nitrate decreased LV volumes ~5%, representing new, sustained, BP‐independent benefits on cardiac structure, extending mechanisms characterised in pre‐clinical models of heart failure. (kcl.ac.uk)

1993. The effects of nitrate, nitrite and N-nitroso compounds on human health: a review. (cdc.gov)
Thus, the assessment of the health risk of nitrate to humans should encompass the toxicity of both nitrite and N-nitroso compounds, and the animal species used for safety evaluation should be closely related to humans with respect to the toxicokinetics of nitrate and the conversion of nitrate to nitrite. (inchem.org)
Furthermore, in the toxicological evaluation of nitrate, it should be considered in conjunction with nitrite and potential endogenously formed N-nitroso compounds. (inchem.org)
However, fruit juices contain beneficial compounds such as vitamin C and flavonoids and could be a useful source of dietary phytochemicals. (cambridge.org)

He explained that the product used was a formulation of dietary inorganic nitrates given as potassium nitrate capsules, which the study investigators produced specifically for this trial. (medscape.com)

In aged mice with preserved systolic function, dietary nitrate supplementation improved LV diastolic function, arterial compliance, and coronary flow reserve. (nih.gov)

When consumed, these nitrates are converted into nitrite in the body through a process involving the salivary glands. (evidencebasedmuscle.com)

This latter finding is very interesting from a nutritional point of view, since nitrate is abundant in our diet (mainly in green leafy vegetables). (sciencewatch.com)
1 The most recent U.S. Dietary Guidelines (2015-2020) recommended that consumers incorporate nutrient-dense foods, including a variety of vegetables and fruits, into their diets. (naturalproductsinsider.com)

However, both articles reported significant VO2 max increases across all diets, and that outcomes were independent of dietary intervention. (pearltrees.com)
Interestingly, both studies were conducted among elite race walkers that self-selected their dietary intervention, and the athletes that self-selected into the EAKD had slightly higher average baseline and post-treatment VO2 max values [7, 12]. (pearltrees.com)
In the chronic intervention study FVPD consumption was found to significantly increase dietary carotenoids ( P =0·001) and vitamin C ( P =0·003). (cambridge.org)
In the acute intervention study FVPD were found to increase total plasma nitrate and nitrite ( P =0·001) and plasma vitamin C ( P =0·002). (cambridge.org)

We hypothesized that increased abundance of nitrate‐reducing oral bacteria would be associated with lower levels of cardiometabolic risk cross‐sectionally. (ahajournals.org)

In demonstrating that nitrate is likely to underlie the cardio-protective effect of a vegetable-rich diet, the research of Professor Ahluwalia and her colleagues highlights the potential of a natural, low cost approach for the treatment of cardiovascular disease -- a condition that kills over 110,000 people in England every year. (sciencedaily.com)

The paper, 'Acute blood pressure lowering, vasoprotective and anti-platelet properties of dietary nitrate via bioconversion to nitrite', is published online in the March 2008 edition of Hypertension . (sciencedaily.com)
Introduction Nutrient timing is a dietary strategy in which specific nutrients are ingested at certain times surrounding training in order to bolster acute performance and/or chronic adaptations [1]. (pearltrees.com)

Although calcium oxalate is the most common compound in kidney stones, consuming some dietary calcium helps reduce the risk of stones. (medicalnewstoday.com)

These results suggest that a moderate dose of dietary nitrate may support microvascular function, which is related to improvements in walking distance and claudication in patients with PAD. (artinis.com)
Allow 48h after last tadalafil dose before nitrate administration. (medscape.com)

While many swear by the tried-and-true ingredients like caffeine, creatine, citrulline, and beta-alanine, there's a burgeoning interest in the dietary nitrate supplementation benefits. (evidencebasedmuscle.com)
Effects of dietary nitrate, caffeine, and their combination on 20-km cycling time trial performance. (herts.ac.uk)

Consider whether menstrual cycle phase alters the response to nitrate supplementation through comparisons of the effects observed between two or more phases. (acsm.org)
If the decision to trial nitrate is taken, we suggest that female athletes rigorously and systematically test nitrate supplementation in, preferably in repeated competition simulations and compare it to their performance without nitrate, to verify if this strategy can enhance exercise performance and does not lead to side effects (e.g., mild gastrointestinal problems). (acsm.org)
The study is a systematic review and meta-analysis of studies on the effects of nitrate supplementation on exercise performance. (evidencebasedmuscle.com)
I have written about nitrates beneficial effects in may article on Evidence Based Muscle here , here , and here . (evidencebasedmuscle.com)
Studies have also shown that nitrate supplementation can lead to favorable effects on blood pressure, glucose metabolism, and cardiovascular health. (evidencebasedmuscle.com)

Our recently published article in the Translational Journal of the American College of Sports Medicine aimed to highlight this discrepancy in the literature, namely that there is currently insufficient evidence to draw strong conclusions about the efficacy of nitrate supplementation for female athletes. (acsm.org)
The proposed study will investigate the efficacy of dietary nitrate supplementation on cardiovascular and cerebrovascular hemodynamics in patients recently diagnosed with TIA. (longdom.org)

In the dog, in addition to strong salivary secretion, large quantities of nitrate were excreted in the bile following i.v. administration of nitrite, thus confirming this pathway of excretion as well as oxidation of nitrite in vivo (Walker, in press). (inchem.org)

They are normally consumed with water and have a higher nitrate content than regular beet powder on a per gram basis ( 1 ). (righthealth.com)

We suggest that female athletes consult with a registered dietitian to determine the need for nitrate supplementation. (acsm.org)

The associations between individual dietary sugar types and the risk of coronary heart disease. (news-medical.net)

Nitric oxide bioavailability increases following nitrate supplementation wherein oral microbiota facilitate the metabolism and absorption of nitrate. (wku.edu)

2008) These nitrates, when ingested, are converted into nitric oxide, a molecule known to enhance blood flow and muscle power. (evidencebasedmuscle.com)
Does dietary nitrate help decrease high blood pressure? (medicalnewsbulletin.com)
As dietary nitrate appears to be an important contributor to nitric oxide signalling, many studies have investigated the potential mechanism and the role it plays in regulating blood pressure. (medicalnewsbulletin.com)
Nitrates can help open up the blood vessels in the body, increasing blood flow and delivery of oxygen around the body. (askmen.com)

Dietary nitrate supplementation benefits include health benefits such as combating hypertension, a major risk factor for heart diseases, are also noteworthy. (evidencebasedmuscle.com)
2006. Dietary approaches to prevent and treat hypertension: a scientific statement form the American Heart Association. (cdc.gov)

Abstaining from consuming animal protein results in lower dietary intakes of cholesterol, saturated fats and total fats, another health benefit to vegetarianism. (naturalproductsinsider.com)
Most studies have used nitrate in water supplies as a proxy for individual exposure, but dietary intakes and other factors may contribute to the exposure. (cdc.gov)

Anatomy5

Organisms4

Diseases2

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Psychiatry and Psychology1

Phenomena and Processes11

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture14

Health Care8

Beetroot26

Inorganic nitrate10

Sodium11

Juice5

Beets7

Nitrites and nitrates2

Placebo4

Supplementation has been shown1

Supplements10

Nitric oxide levels1

Ingestion2

Skeletal muscle4

Ascorbic Acid1

Effect of nitrate2

Oral microbiome3

Physiological effects1

Intake11

Nitrite concentration2

Endothelial function3

Antioxidants1

Fiber2

Gastric3

Oxidative1

Therapeutic4

Supplement3

Reduction5

Association between dietary2

Cardiac3

Compounds4

Potassium1

Systolic1

Salivary glands1

Vegetables2

Intervention4

Bacteria1

Cardiovascular disease1

Acute2

Calcium1

Dose2

Caffeine2

Effects5

Efficacy2

Excretion1

Beet1

Athletes1

Coronary1

Metabolism1

Blood4

Hypertension2

Intakes2