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  • urine
  • Therefore, since 1827 physicians and scientists have been interested in proteinuria, the excess of protein in human urine, as an indicator of kidney disease. (wikipedia.org)
  • Between 1932 and 1933 a number of scientists, including Thomas Addis, independently reported the surprising finding that some healthy rodents have protein in their urine. (wikipedia.org)
  • It was found that the proteins are primarily made in the liver of males and secreted through the kidneys into the urine in large quantities (milligrams per day). (wikipedia.org)
  • This syndrome is diagnosed through clinical evaluation and a fresh urine sample Children with blue diaper syndrome are put on restricted diets. (wikipedia.org)
  • Prenatal
  • From these studies it is possible to conclude that prenatal protein nutrition is vital to the development of the fetus, especially the brain, the susceptibility to diseases in adulthood, and even gene expression. (wikipedia.org)
  • Diseases
  • Sodium phenylbutyrate is also a histone deacetylase inhibitor and chemical chaperone, leading respectively to research into its use as an anti-cancer agent and in protein misfolding diseases such as cystic fibrosis. (wikipedia.org)
  • calcium
  • Fetal exposure to calcium, folate, magnesium, high or low protein, and zinc have all been associated with birth weight. (wikipedia.org)
  • Low protein consumption appears to alter the risk of bone breakage, presumably through changes in calcium homeostasis. (wikipedia.org)
  • Bone
  • A positive correlation was observed between bone mass and plasma thyroid hormone levels and ALP activity and plasma protein levels, and a negative correlation with ACP activity. (biomedsearch.com)
  • Methylation
  • The methyl groups used in DNA methylation are often derived from dietary sources, such as folate and choline, and explains why diet can have a significant impact on methylation patterns and gene expression. (wikipedia.org)