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  • Diazepam is a drug used to treat mild to moderate anxiety and tension and to relax muscles. (news-medical.net)
  • For example, benzodiazepine drug discrimination has been extensively studied and characterized using training drugs such as diazepam (e. (thefreedictionary.com)
  • Both medications are in a class of drugs called benzodiapines, with diazepam the more commonly used anti-seizure drug in pre-hospital settings. (thefreedictionary.com)
  • In humans, measurable blood levels of diazepam were obtained in maternal and cord blood, indicating placental transfer of the drug. (nih.gov)
  • Diazepam is contraindicated in patients with a known hypersensitivity to this drug and, because of lack of sufficient clinical experience, in children under 6 months of age. (nih.gov)
  • Diazepam is the drug of choice for treating benzodiazepine dependence with its long half-life allowing easier dose reduction. (wikipedia.org)
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  • No-one seems to be helping my dad as I said they thought his nausea was pyschological and thats why they put him on diazepam, but also he was taking an anti sickness drug called cyclocine (don't know how its spelt). (healingwell.com)
  • Diazepam is the drug of choice for treating benzodiazepine dependence with its long half-life allowing easier dose reduction. (wikipedia.org)
  • Never share diazepam with another person, especially someone with a history of drug abuse or addiction. (cigna.com)
  • Diazepam is a controlled substance Accordingly, the Food and Drug Administration (FDA) and the Drug Enforcement Agency of the United States (and similar regulatory agencies in other countries) strictly control these drugs. (petplace.com)
  • Diazepam is classified as a benzodiazepine class drug. (petplace.com)
  • Diazepam is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. (petplace.com)
  • Diazepam should not be used in animals with known hypersensitivity or allergy to the drug. (petplace.com)
  • In some animals, however, diazepam causes the paradoxical drug reaction of excitement. (petplace.com)
  • Diazepam is a controlled drug because it has high abuse potential in people. (petplace.com)
  • Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. (nih.gov)
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  • Click Diazepam Side Effects to learn about other potentially serious diazepam reactions and for information about other common side effects of this drug. (emedtv.com)
  • Before you take diazepam, tell your doctor if you have glaucoma, asthma or other breathing problems, kidney or liver disease, seizures, or a history of drug or alcohol addiction , mental illness, depression , or suicidal thoughts . (emedicinehealth.com)
  • Diazepam is sometimes used as an appetite stimulant but its sedating properties preclude it from being the drug of choice for this purpose. (marvistavet.com)
  • Diazepam is a generic drug with the brand name Valium. (therecoveryvillage.com)
  • There are risks associated with the use of benzos like diazepam, but they remain one of the most commonly prescribed drug classes in the U.S. Diazepam and other benzos are believed to work by stimulating a calming or tranquilizing brain chemical. (therecoveryvillage.com)
  • Diazepam shouldn't be mixed with certain other substances or drug classes. (therecoveryvillage.com)
  • 3 mg/kg) or diazepam (2.5 mg/kg) from vehicle in two-lever drug discrimination procedures for food reinforcement. (rti.org)
  • However, the fact that diazepam produced partial substitution for Delta(9)-THC is consistent with a GABAergic component to cannabinoid drug discrimination. (rti.org)
  • Drug treatment of breathlessness: contrasting effects of diazepam and promethazine in pink puffers. (biomedsearch.com)
  • The aim of the present study was to investigate the feasibility of the inclusion of a water-insoluble drug (diazepam, DZ) into solid lipid nanoparticles (SLNs), which offer combined advantages of rapid onset and prolonged release of the drug. (pubmedcentralcanada.ca)
  • Learn the ins and outs of the regulated prescription drug diazepam. (study.com)
  • Diazepam is a powerful drug that has lessened anxiety and improved the quality of life for a number of people, but it can have serious side effects when misused and may even cause death. (study.com)
  • As a result, if improperly used, diazepam may actually increase anxiety levels to those higher than the patient experienced before they started taking the drug! (study.com)
  • Diazepam is a useful prescription drug when used properly for the treatment of anxiety, seizures, muscle spasms, and a number of other medical problems. (study.com)
  • Misuse of diazepam may lead to addiction and consequently severe withdrawal symptoms when use of the drug ceases. (study.com)
  • This is not a complete list of diazepam drug interactions. (medicineshoppe.com)
  • Diazepam is a habit-forming drug that is used for a variety of conditions. (pscard.com)
  • Every person who has developed physical dependence on diazepam will likely experience uncomfortable symptoms after discontinuing this drug. (addictionblog.org)
  • Once a significant level of physiological dependence has developed, a person is likely to experience diazepam withdrawal symptoms when they stop their drug use. (withdrawal.net)
  • Although people who abuse or chronically use diazepam are more likely to experience withdrawal symptoms, people who have used the drug for as little as 2-4 weeks may also have symptoms. (withdrawal.net)
  • If you have taken diazepam for longer than 2 weeks, you may benefit from a tapering of the drug to help minimize your risk of experiencing severe withdrawal effects. (withdrawal.net)
  • Diazepam is a benzodiazepine derivative drug commonly used to treat a wide range of conditions including anxiety and insomnia. (acris-antibodies.com)
  • Diazepam is seen as an essential drug by the World Health Organisation, but it is excreted into waste water treatment works because people take more than can be metabolised in their body. (phys.org)
  • Diazepam gel was better than placebo gel in reducing the risk of non-cessation of seizures. (wikipedia.org)
  • Sex differences in the effect of diazepam on psychomotor skills were investigated in two placebo-controlled double-blind trials. (janusinfo.se)
  • In the first trial, healthy volunteers (78 men, 78 women) were divided into four groups receiving either an oral dose of 10 mg diazepam, placebo, alcohol in addition to diazepam, or a nonalcoholic drink in addition to placebo. (janusinfo.se)
  • In the second trial, subjects received diazepam or placebo in doses corrected for body weight. (janusinfo.se)
  • Participants will randomly be assigned by a computer-derived random number sequence (after pregnancy is ruled out) to either the treatment group (intravaginal diazepam) or the placebo group Investigators and patients will be blinded to group assignment. (clinicaltrials.gov)
  • The placebo or diazepam tablet will be distributed to the participant in the examining room on the day of allocation. (clinicaltrials.gov)
  • The participant will be instructed to insert the diazepam or placebo tablet into her vagina at home. (clinicaltrials.gov)
  • The placebo group will receive the standard conservative therapy, and an intravaginal tablet (visually indistinguishable from diazepam) commercially produced by the university pharmacy. (clinicaltrials.gov)
  • Diazepam (0.33 mg per kilogram of body weight) or placebo was administered orally every eight hours during all febrile illnesses. (nih.gov)
  • Fifteen out of 18 "pink and puffing" patients completed a double-blind, placebo-controlled cross-over trial of diazepam and promethazine for breathlessness and reduced exercise tolerance. (biomedsearch.com)
  • Of the three patients who did not complete the trial, one died during an exacerbation of breathlessness while taking diazepam, one was withdrawn because of mild hypercapnia while taking placebo, and one suffered intolerable drowsiness while taking diazepam. (biomedsearch.com)
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  • A series of rat reproduction studies was performed with diazepam in oral doses of 1, 10, 80 and 100 mg/kg. (nih.gov)
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  • In one study in mice, oral administration of diazepam enhanced the occurrence of hepatocellular tumours induced by N -nitrosodiethylamine. (inchem.org)
  • The extent of this is not of that magnitude that dose adjustment normally will be needed .In vitro data has shown that free fraction of diazepam was higher in women taking oral contraceptives than in women not taking oral contraceptives. (janusinfo.se)
  • Women without oral contraceptives had higher free fraction of diazepam than men . (janusinfo.se)
  • In part, these findings are supported by a small single-dose study (6 men, 5 women on oral contraceptives) on diazepam disposition. (janusinfo.se)
  • 4 Giving diazepam by mouth is difficult and hazardous when the dog is actively seizing, and absorption after oral administration is slow and unpredictable.4 On the other hand, rectal administration of diazepam results in higher and earlier blood levels compared with either oral or intramuscular routes, making this route of administration ideal for home treatment of cluster seizures. (canine-epilepsy.com)
  • Oral diazepam, given only when fever is present, is safe and reduces the risk of recurrent febrile seizures. (nih.gov)
  • Any increase in enzymes precludes the use of oral diazepam in such a patient. (marvistavet.com)
  • Effects of diazepam premedication and epinephrine-containing local anesthetic on cardiovascular and plasma catecholamine responses to oral surgery. (emedexpert.com)
  • Using diazepam rectal daily over long periods can actually make your seizures more frequent or more severe. (cigna.com)
  • Although rare, diazepam can cause a severe liver problem in cats that can be fatal. (petplace.com)
  • You should not use this medicine if you are allergic to diazepam or similar medicines (Klonopin, Xanax, and others), or if you have myasthenia gravis, severe liver disease, narrow-angle glaucoma, a severe breathing problem, or sleep apnea. (wellspan.org)
  • Current recommendations are for the administration of diazepam for seizures due to nerve agent poisoning and even for severe toxicity (severe respiratory distress or neuromuscular signs) in the absence of seizures. (cdc.gov)
  • A. Diazepam is recommended for severe nerve agent poisoning even in the absence of seizures. (cdc.gov)
  • Veterinarians typically administer diazepam by vein to quickly stop a seizure, but most clients are not adept at intravenous injections. (canine-epilepsy.com)
  • In the absence of α 1 subunits, a receptor was formed that was gated by GABA and modulated by diazepam similarly. (nature.com)
  • From this mutation work we conclude that the site for GABA is located at a β 2 +/β 2 − subunit interface and that the diazepam site is located at the β 2 +/γ 2 − subunit interface. (nature.com)
  • Thus, the β 2 subunit can take over the role of the α 1 subunit for the formation of both sites, its minus side for the GABA binding site and its plus side for the diazepam binding site. (nature.com)
  • Diazepam and other benzos are thought to improve the effectiveness of GABA, creating a tranquilized brain effect. (therecoveryvillage.com)
  • Usage in Pregnancy: An increased risk of congenital malformations associated with the use of minor tranquilizers (diazepam, meprobamate and chlordiazepoxide) during the first trimester of pregnancy has been suggested in several studies. (healthyplace.com)
  • DIAZEPAM is the brand name diazepam sale a specific benzodiazepine receptors have been deinstitutionalized. (angelfire.com)
  • These results suggest that the partial overlap in the discriminative stimulus effects of Delta(9)-THC and diazepam is not mediated by diazepam action at CBI receptors. (rti.org)
  • Over-simplified, when a person is feeling jumpy or on edge and their neurons are over-firing, diazepam comes in and gives the excited receptors a hug, ultimately calming them down and producing an overall feeling of relaxation. (study.com)
  • I recently got 1 milligram clonazepam and 10 milligram diazepam.Im not sure what one of the 2 pills are stronger,n i also would like to know how many,1mlg.clonazepam equal a 1 mlg zanax. (medhelp.org)
  • I really need to figure out how many of the diazepam,n how many of the clonazepam equal a 1 mlg zanax. (medhelp.org)
  • Clonazepam is 10 20 times more potent than diazepam. (emedexpert.com)
  • Consult with your veterinarian to determine if other drugs your pet is receiving could interact with diazepam. (petplace.com)
  • Grapefruit and grapefruit juice may interact with diazepam and lead to potentially dangerous effects. (medicineshoppe.com)