• The distribution of LV diastolic dysfunction after the CR exercise program was changed significantly only in the CR group (p value = 0.043). (ac.ir)
  • This distribution was changed respectively to 30.1, 61.6, 5.4, and 2.7 following CR, which showed a significant improvement due to CR in LV diastolic function, most prominently in the patients with grade I diastolic dysfunction (p value = 0.390). (ac.ir)
  • CONCLUSION: The RC exercise program can be effective in the augmentation of LV diastolic dysfunction after PCI, without significant changes in LV diameters. (ac.ir)
  • Echocardiograms demonstrated vigorous systolic function but substantial diastolic dysfunction of the left ventricle in all. (nih.gov)
  • The main pathophysiological correlate is impaired left ventricular filling, resulting in diastolic dysfunction with increased end-diastolic left ventricular pressure ( P LV,ED ), with consequent pulmonary congestion, increased stimulation of pulmonary vagal irritant receptors (J-receptors) and enhanced chemosensitivity of central and peripheral carbon dioxide receptors. (ersjournals.com)
  • Myocardial strain imaging, a reproducible measure of LV systolic function, can identify subclinical LV dysfunction and patterns that suggest specific cardiomyopathies (eg, ischemic cardiomyopathy, amyloidosis, hypertrophic cardiomyopathy, chemotherapy-induced cardiotoxicity). (medscape.com)
  • In patients with ischemic cardiomyopathy, TTE may show segmental areas of systolic dysfunction that are typically localized to a coronary distribution. (medscape.com)
  • Several structural abnormalities, such as myocyte hypertrophy, diffuse interstitial myocardial fibrosis, and impaired coronary microvascular perfusion, have been associated with diabetic hearts, as well as diastolic and systolic dysfunction. (news-medical.net)
  • Left ventricular remodeling after acute myocardial infarction (MI) is a complex pathological process producing alterations in topography of both the infarcted and non-infarcted regions of the ventricle leading to progressive dilatation and systolic dysfunction (2). (escardio.org)
  • This data suggested that acute oral sildenafil improved systolic and diastolic dysfunction in HF dogs. (vin.com)
  • Hypertrophic Cardiomyopathy Hypertrophic cardiomyopathy is a congenital or acquired disorder characterized by marked ventricular hypertrophy with diastolic dysfunction (eg, due to valvular aortic stenosis, coarctation. (msdmanuals.com)
  • However, left ventricular diastolic dysfunction, left atrial enlargement, and increased left ventricular mass index (LVMI) were more prevalent among the patients with CLD compared to controls (P (bvsalud.org)
  • Conclusion: The study demonstrated increased left atrial diameter, increased LVMI associated with diastolic dysfunction, and preserved systolic function at rest among CLD patients. (bvsalud.org)
  • BACKGROUND: To support the clinical distinction between systolic heart failure (SHF) and diastolic heart failure (DHF), left ventricular (LV) myocardial structure and function were compared in LV endomyocardial biopsy samples of patients with systolic and diastolic heart failure. (amsterdamumc.org)
  • Left ventricular (LV) ejection fraction, LV diastolic function, LV end-systolic and diastolic diameter, and right ventricular (RV) end-diastolic diameter were measured in the CR group before and after rehabilitation and compared to those in the control group at the same times. (ac.ir)
  • The opening of an infarct-related artery may improve ventricular function, collateral blood flow, and ventricular remodeling, and it may decrease infarct expansion, ventricular aneurysm formation, left ventricular (LV) dilatation, late arrhythmia associated with ventricular aneurysms, and mortality. (medscape.com)
  • Left ventricular systolic function is normal. (medhelp.org)
  • Left ventricular diastolic function was normal. (medhelp.org)
  • Normal right ventricular cavity size and systolic function noted. (medhelp.org)
  • Heart failure with normal left ventricular ejection fraction (HFNEF) is a clinical entity that embodies symptoms of heart failure in the presence of preserved systolic function of the left ventricle. (ersjournals.com)
  • These indices could complement conventional analysis of left ventricular function and contribute to the early accurate detection of cardiomyopathy in cats. (avma.org)
  • Right ventricular (RV) diastolic stiffness is increased in pulmonary arterial hypertension (PAH) patients. (ersjournals.com)
  • a measure of ventricular contractile function) in PAH patients [ 1 - 6 ]. (ersjournals.com)
  • AF could lead to the loss of atrial systolic function and ventricular irregular contraction and then promote the decline of cardiac diastolic function. (hindawi.com)
  • Evaluation of the left ventricular systolic and diastolic functions by echocardiography in patients with acute leukemia. (florence.com.tr)
  • Results indicated that left ventricular diastolic and systolic function declined at a younger age in males than in females. (avma.org)
  • This study aimed to assess acute effects of sildenafil on LV functions by using echocardiography in heart failure dogs induced by rapid right ventricular pacing. (vin.com)
  • Our aims were (i) to evaluate and compare levels of CMD in patients with TTS and patients with ischaemia and no obstructive coronary arteries (INOCA) and (ii) to investigate associations between CMD and clinical parameters, left ventricular function, and coronary atherosclerosis in TTS. (lu.se)
  • In the TTS patients, left ventricular function was assessed with echocardiography and cardiovascular magnetic resonance (CMR) imaging, and coronary atherosclerosis was visualized with intravascular ultrasound with near-infrared spectroscopy (IVUS-NIRS). (lu.se)
  • CFR and RRR correlated inversely with CMR-derived end-diastolic volume index, end-systolic volume index, and left ventricular mass index. (lu.se)
  • CMD in TTS is more severe in the apical compared with the midventricular phenotype of the syndrome, is associated with left ventricular function, but is unrelated to coronary atherosclerosis. (lu.se)
  • TTE is a relatively inexpensive and non-invasive imaging technique for diagnosis of right and left ventricular function and wall motion, chamber size and anatomy, valvular structure function, aortic root structure and intracardiac pressures. (msdmanuals.com)
  • Disorders of ventricular function in cardiomyopathies]. (bvsalud.org)
  • Changes in the systolic and diastolic ventricular function during and following ventriculography]. (bvsalud.org)
  • Imaging is also useful in detecting pericardial effusion, concomitant valvular or congenital heart disease, and marked depression of ventricular function that may interdict treatment in the acute phase with beta-adrenergic blockers. (medscape.com)
  • The aim of the study was to evaluate the left atrial and ventricular geometry, systolic and diastolic functions in patients with CLD. (bvsalud.org)
  • In addition, significant positive effects could be confirmed on absolute and predicted peak oxygen consumption, oxygen consumption at the individual aerobic-anaerobic threshold, oxygen pulse, as well as left atrial size, and transmitral flow patterns (mean early diastolic lengthening velocity and the ratio of peak early Doppler mitral inflow velocity to this lengthening velocity). (ersjournals.com)
  • Similar to persistent AF, paroxysmal atrial fibrillation (PAF) could also have a significant impact on cardiac diastolic function. (hindawi.com)
  • However, the ECG predictive models that were generated only accounted for 17%, 7%, 11%, and 8% of the variance in the right atrial end-systolic area, left atrial end-systolic area, MLVWT, and LVIDd, respectively. (avma.org)
  • Two-dimensional transthoracic echocardiography can confirm the clinical diagnosis of aortic stenosis and provide specific data on LV function. (medscape.com)
  • 1912. "Clinical investigation of cardiovascular function", 1934. (wikipedia.org)
  • Neutral impact on systolic and diastolic cardiac function of 2 years of intensified multi-intervention in type 2 diabetes: The randomized controlled Asker and Bærum Cardiovascular Diabetes (ABCD) study. (uib.no)
  • The authors were unable to account for these findings and concluded that any improvements in cognitive function were largely dependent on baseline levels of adiposity and cardiovascular disease history. (hospitalhealthcare.com)
  • Only recently TRT was not clearly associated with adverse cardiovascular (CV) events, but its impacts on endothelial function are still controversial. (usp.br)
  • Objectives: The term cirrhotic cardiomyopathy (CCM) has been used to describe the constellation of cardiovascular abnormalities including diastolic and systolic dysfunctions in patients with chronic liver disease (CLD). (bvsalud.org)
  • Based on the influence of the defensive hostility in the cardiovascular diseases, as a possible psychosocial risk factor, by the excessive functioning of the cardiovascular system, in the present study we plan to examine in a much more detailed and thorough manner this functioning along the three experimental phases in the laboratory: adaptation, task and recovery. (bvsalud.org)
  • The main aim has been to analyze the relationship between defensive hostility and cardiovascular functioning intra phase in detail. (bvsalud.org)
  • The results show that defensive hostile individuals presented the highest values registered in physiological variables as well as some less adaptive profiles, supporting the hypothesis about the greater predictive power of defensive hostility in relation to the cardiovascular functioning stress situations. (bvsalud.org)
  • Some prefer the term "periodic" since the term "triphasic" already has a specific application in arterial spectral Doppler waveforms and since "periodic" suggests that the waveform is transmitted by cardiac motion rather than systolic flow. (radiopaedia.org)
  • The diastolic function about the indices of NT-proBNP, E / e ′, e ′ was improved in the decreasing HR group, the decreasing mean arterial pressure (MAP) group, and the HFPEF group, correspondingly compared to the nondecreasing HR group, the non-decreasing MAP group, and the preoperative normal diastolic function group. (hindawi.com)
  • It defines stage 1 hypertension as 140 to 159 mm Hg systolic and 90 to 99 mm Hg diastolic and stage 2 hypertension as a systolic of 160 mm Hg or greater and diastolic of 100 mm Hg or greater. (medpagetoday.com)
  • Fenoldopam is indicated for in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function. (rxlist.com)
  • Hypertension and PAF can affect cardiac diastolic function. (hindawi.com)
  • The study aimed to evaluate the effect of RDN on cardiac diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • RDN could improve the diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • Long-term hypertension, especially long-term uncontrolled hypertension, could directly lead to myocardial hypertrophy, myocardial wall stiffness, and compliance decline, eventually causing a decrease in diastolic function. (hindawi.com)
  • In this study, we studied the changes in diastolic function in patients with refractory hypertension and PAF before and after RDN. (hindawi.com)
  • Hypertension (resting systolic BP above 150 or diastolic above 95 mm Hg). (who.int)
  • Assessment of heart rate variability (HRV), orthostatic hypotension, and 24 h blood pressure profiles provide indices of both parasympathetic and sympathetic autonomic function and can be used in clinical settings. (hindawi.com)
  • We investigated whether RV diastolic stiffness is associated with clinical progression and assessed the contribution of RV wall thickness to RV systolic and diastolic stiffness. (ersjournals.com)
  • RV diastolic stiffness is related to clinical progression in both baseline and treated PAH patients. (ersjournals.com)
  • Cell therapy is currently emerging as a potential new treatment for post MI patients with the assumption that recolonization of the areas of scarred myocardium with exogenously supplied surrogates or precursors of cardiomyocytes can restore function and ultimately affect clinical outcomes. (escardio.org)
  • Recent clinical studies of sildenafil in patients and rats with HF have reported improved cardiac functions. (vin.com)
  • The study explores the hypothesis by investigating effects of consumption of 1000 mg of PSO on total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), systolic (SBP) and diastolic (DBP) blood pressure ((BP). (scielo.br)
  • A study of elderly clergy, both men and women, found a significantly accelerated decline in leg function in those with higher blood pressures-about 30% more loss per year at a systolic pressure of 160 mm Hg compared with 120 mm Hg. (medpagetoday.com)
  • Participants in the current study were evaluated for cognitive function, vascular disease, diabetes, and blood pressure at baseline. (medpagetoday.com)
  • The average systolic and diastolic blood pressures were 135 mm Hg and 75 mm Hg, respectively. (medpagetoday.com)
  • Each 10 mm Hg increase in systolic blood pressure was associated with a significant increase in the rate at which leg function declined ( P =0.011). (medpagetoday.com)
  • A diastolic blood pressure greater than 90 mm Hg ( P =0.023) (rather than continuous measures) were also associated with a decline in gait over time. (medpagetoday.com)
  • Interestingly, although the inclusion of individuals who had a previous stroke did not diminish the association between leg function and blood pressure, controlling for strokes that occurred during the study eliminated the significance of the association ( P =0.099). (medpagetoday.com)
  • Controlling for baseline factors including cognitive function, diabetes, previous myocardial infarction, and leg claudication did not affect the association between systolic blood pressure and walking ability. (medpagetoday.com)
  • The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure's seventh blood pressure guidelines report (JNC VII) defines normal blood pressure as systolic of less than 120 and diastolic less than 80 mm Hg. (medpagetoday.com)
  • The cadmium workers had higher mean systolic and diastolic blood pressures than did referents. (cdc.gov)
  • blood organic mercury and blood total mercury were grouped in cluster 4, and cluster 6 included the liver function enzymes ALT, AST and GGT. (medrxiv.org)
  • Primary outcomes were changes in mean hemoglobin A1c (HbA1c) and mean systolic and diastolic blood pressure at baseline and at 12 months. (cdc.gov)
  • however, further research is warranted to examine isolated and combined impacts of blood pressure, age, body weight, and anesthetic agents on cardiac structure and function in chimpanzees. (avma.org)
  • Their visual and auditory patients with some degree of systolic dys- systems were also checked, and renal func- function, continuous IV infusion of deferox- tion tests and blood sugar were measured. (who.int)
  • Other blood tests are done to check heart and kidney functions and to check for infection. (medlineplus.gov)
  • Heart failure develops when the heart, via an abnormality of cardiac function (detectable or not), fails to pump blood at a rate commensurate with the requirements of the metabolizing tissues or is able to do so only with an elevated diastolic filling pressure. (medscape.com)
  • The physiological variables registered throughout all phases were: heart rate, systolic blood pressure and diastolic blood pressure. (bvsalud.org)
  • In the MOS cohort (Paper II), we found that adults born with low birth weight (LBW) but who attained a higher body mass index (BMI) at age 20 (mismatch) had significantly higher systolic and diastolic blood pressure (BP) compared to those born with LBW but continued to have low BMI at age 20. (lu.se)
  • The assessment of cardiac function is achieved by the detection and automated analysis of systolic and diastolic heart sounds and their temporal relationships to the electrocardiogram. (thoracickey.com)
  • Assessment of segmental function and overall LV performance provides prognostic information and is essential when MI is extensive, as judged by use of enzymatic criteria, or when MI is complicated by shock or profound HF. (medscape.com)
  • For the cognitive assessment arm, 1089 participants from the original study were recruited at year 8 or 9 of follow-up and undertook 2 or 3 cognitive assessments, that evaluated verbal learning, memory, speed of processing, executive function and global cognitive functioning. (hospitalhealthcare.com)
  • CONCLUSIONS: LV myocardial structure and function differ in SHF and DHF because of distinct cardiomyocyte abnormalities. (amsterdamumc.org)
  • ASV effectively attenuates CSR in patients with HFNEF and improves heart failure symptoms and cardiac function. (ersjournals.com)
  • The Aim of the present study was to examine whether there is a relationship between autonomic nervous system function and glycemic variability (GV) in patients with type 2 diabetes (T2D). (hindawi.com)
  • We aimed to investigate the association between 25(OH)D and islet function homeostasis in type 2 diabetes (T2D) patients. (researchsquare.com)
  • Duration of diabetes influence the effect of 25(OH)D on the ratio of glucagon/C-p, on behalf of islet function homeostasis, in T2D patients with abdominal obesity. (researchsquare.com)
  • The 190 patients were divided into the decreasing HR and nondecreasing HR group, the decreasing MAP and nondecreasing MAP group, the HFPEF group, and the normal diastolic function group, respectively. (hindawi.com)
  • Theoretically, the RDN also has a certain effect on cardiac diastolic function in these patients. (hindawi.com)
  • Several preliminary reports have demonstrated that local stem cell transplantation in patients with acute myocardial infarction is safe and may lead to improved myocardial function and perfusion. (escardio.org)
  • The commonest treatment for thalas- sion in thalassaemia patients with some saemia patients, apart from bone marrow degree of systolic function impairment. (who.int)
  • Haemosiderosis, which plays a considerable function in thalassaemia patients before and role in early mortality, can be prevented or after treatment with high-dose deferoxam- postponed by iron-chelating agents which ine. (who.int)
  • Efforts have been made to establish a the patients to determine pulse rate interval, safe treatment of cardiac complications in QRS duration, arrhythmia and systolic and thalassaemia patients. (who.int)
  • A power function of age was used to describe age-related differences in baseline MAP. (frontiersin.org)
  • Anthropometric indices, biochemical parameters, serum 25(OH)D, and islet function including C-peptide (C-p) and glucagon were measured. (researchsquare.com)
  • Before RDN, the indices about cardiac diastolic function were out of the normal range. (hindawi.com)
  • CMR imaging is used to determine HF due to its capacity to assess myocardial tissue characteristics, cardiac morphology, and function. (news-medical.net)
  • This suggests that intrinsic myocardial changes play a distinctive role in explaining RV diastolic stiffness at different stages of PAH. (ersjournals.com)
  • Taken together, these data lead to the question of whether duration (chronic versus short-term) is a key determinant of CR-induced changes in muscle mitochondrial mass and function. (medscape.com)
  • Disability, as measured by reduced physical functioning (1,2), frailty (3,4), and decreased cognitive functioning (5-8), is commonly reported among people with chronic kidney disease (CKD) and end-stage renal disease. (cdc.gov)
  • Prenatal insults or adverse events during the in-utero period may lead to suboptimal function of adult organs because of the impairment of critical organ development and growth, as linked to lower birth weight. (lu.se)
  • Coronary microvascular function was quantified invasively using the index of microcirculatory resistance (IMR), coronary flow reserve (CFR), and resistive reserve. (lu.se)
  • Advocated Doppler parameters include the aortic velocity-time integral (VTI), diastolic mitral inflow pattern, Doppler tissue imaging, and Doppler-derived dP/dt. (thoracickey.com)
  • Liver function tests provide added diagnosis and treatment information. (medlineplus.gov)
  • Impaired liver or kidney function. (who.int)
  • To comprehensively characterize cardiac structure and function, from infancy to adulthood, in male and female wild-born captive chimpanzees ( Pan troglodytes ) living in sanctuaries. (avma.org)
  • Occur- rence of chest pain, palpitations, peripheral oedema, dyspnoea, heart sounds S3, S4 and systolic murmur were determined according to the patient's medical history and physical examination. (who.int)
  • Injection of myoblasts into infarcted myocardium has been shown to augment systolic and diastolic functions in experimental animal studies (7). (escardio.org)
  • So in response to high glucose level or in type 2 diabetes, how 25(OH)D impact glucagon secretion from islet α-cells as well as the islet function homeostasis between islet α-cells and β-cells should be elucidated, which can provide new strategies for treating glucose metabolism disorders. (researchsquare.com)
  • In this study, researchers from several centres in the US have reported on the results from the Action for Health in Diabetes (look AHEAD) study which suggests that it is glycaemic control, rather than weight reduction, which has the greatest impact on cognitive functioning. (hospitalhealthcare.com)
  • However these therapies are of limited value for restoration of cardiac functions after myocardial infarction. (escardio.org)
  • Interestingly, contradictory data exist for transformation of bone marrow derived progenitor cells (BMPC) into new cardiomyocytes and alternative mechanisms as enhanced neovascularization, enhanced scar tissue formation due to augmented inflammatory response and decreased apoptosis have been suggested for the benefical effects of these cells on myocardial function after myocardial infarction (4). (escardio.org)
  • Targeted transcriptional profiling showed no effects on pathways involved inmitochondrial biogenesis, function, or oxidative stress. (medscape.com)
  • Acidosis can have a particularly deleterious effect on myocardial function. (medscape.com)
  • Elevated systolic pressure had the most consistent effect on lower limb function decline. (medpagetoday.com)
  • The effect of chordae tendineae on systolic flow. (uib.no)
  • We also review the cardiac complications of diphtheria and discuss how noninvasive bedside imaging technologies to monitor myocardial function and hemodynamic parameters can help improve the management of this neglected infectious disease. (cdc.gov)
  • Systolic and diastolic function analysis and strain images analysis were performed. (humankinetics.com)
  • One study demonstrated that although lifelong CR preserved muscle mitochondrial function in mice, it did so by protecting the integrity and function of existing mitochondrial cellular components rather than by increasing biogenesis. (medscape.com)
  • Systolic pressures above 160 mm Hg ( P =0.016) were associated with decline in lower limb function. (medpagetoday.com)
  • Specifically, HRV provides a noninvasive and objective method for assessing cardiovagal function and may be derived from electrocardiogram recordings [ 7 ]. (hindawi.com)
  • however, the evidence of their associations with organ function and physiological traits is limited. (lu.se)
  • however, having a "more coupled" (versus "less coupled") phenotype enables CR-induced improvements in muscle mitochondrial function. (medscape.com)
  • However, systolic pressure did not predict the level of limb function itself. (medpagetoday.com)
  • Heart failure (see the images below) may be caused by myocardial failure but may also occur in the presence of near-normal cardiac function under conditions of high demand. (medscape.com)
  • Heart failure always causes circulatory failure, but the converse is not necessarily the case, because various noncardiac conditions (eg, hypovolemic shock, septic shock) can produce circulatory failure in the presence of normal, modestly impaired, or even supranormal cardiac function. (medscape.com)
  • The CR exercise program had useful effects on LV diastolic function after PCI. (ac.ir)
  • Children's exposure to chemotherapeutic agents causes several long-term adverse effects but physical activity has been evidenced to be an effective strategy to improve cardiac function. (humankinetics.com)
  • The effects of caloric restriction (CR) on in vivo muscle mitochondrial function in humans are controversial. (medscape.com)
  • [ 12 ] The activity of key mitochondrial enzymes of the tricarboxylic acid cycle, β-oxidation, and the electron transport system, conversely, were unchanged, [ 12 ] leaving many unanswered questions regarding the effects of CR on muscle-specific mitochondrial function in humans. (medscape.com)
  • To date, there have been no randomized controlled trials that have examined the effects of long-term CR on muscle mitochondrial function in humans. (medscape.com)
  • In one study on 17 diastolic function. (who.int)