Diagnostic leukemia myeloid acute. Medical search. Frequent questions

The findings have been incorporated into clinical trials underway at St. Jude, through the Children's Oncology Group and internationally, that aim to improve cure rates and long-term outcomes for children with acute lymphoblastic leukemia, medulloblastoma, diffuse intrinsic pontine glioma and other childhood cancers. (stjude.org)
The trials include SJMB12, an international clinical trial for young people with medulloblastoma, TOTAL XVII for children with acute lymphoblastic leukemia and others. (stjude.org)
This national multi-center study, led by Genomic Medicine Sweden, aims to evaluate whether combined application of WGS and WTS (WGTS) is technically feasible and can be implemented as an efficient diagnostic tool in patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). (lu.se)
Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). (medlineplus.gov)
This is a type of acute lymphoblastic leukemia that has the Philadelphia chromosome. (medlineplus.gov)

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy. (genomeweb.com)
Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes too many immature white blood cells called myeloblasts. (medicalnewstoday.com)
This initial treatment aims to clear as many leukemia cells as possible in the blood and bone marrow and to induce remission. (medicalnewstoday.com)
Acute myeloid leukemia is a hematopoietic neoplasm of dismal prognosis that results from the accumulation of immature myeloid blasts in the bone marrow and the peripheral blood. (frontiersin.org)
Under the Master Collaboration Agreement, QIAGEN will develop and validate a real-time PCR-based in vitro diagnostic test that can be used to detect IDH1 gene mutations in whole blood and bone marrow aspirates in AML. (servier.com)
If blood tests reveal evidence of leukemia, your doctor will likely want to take a bone marrow biopsy . (healthline.com)
The contribution of the bone marrow (BM) immune microenvironment (TME) to acute myeloid leukemia (AML) development is well-known, but its prognostic significance is still elusive. (ntu.ac.uk)
In Menarini's diagnostics division, one thing that our team is working on is to be able to bring for multiple myeloma (a hematologic area), instead of bone marrow biopsy , a blood test that can enable MRD [minimal residual disease]-negative monitoring with circulating tumor cells. (medscape.com)
Examination of peripheral blood smear and bone marrow is diagnostic. (msdmanuals.com)
PROJECT SUMMARY Acute myeloid leukemia (AML), a malignant disease of hematopoietic precursor cells in the bone marrow, is one of the most common cancers in adults accounting for 1% of all cancers. (sbir.gov)
The results of this evalu- ized by bone marrow proliferation and peripheral blood ation indicated that inaccurate reporting of PV to the PCR erythrocytosis, thrombocytosis, or granulocytoses.1 In addi- led to PV risk estimates that were inflated over true values tion to PV, the MPNs include chronic myeloid leukemia by 13% to 62%2. (cdc.gov)

About 600 to 800 people develop acute promyelocytic leukemia (APL) in the United States each year. (healthline.com)
How is acute promyelocytic leukemia treated? (healthline.com)
Acute promyelocytic leukemia (APL) is a subtype of AML with recurrent genetic abnormalities. (msdmanuals.com)

Gene therapy is under development for the treatment of acute leukaemia such as relapsed and refractory acute myeloid leukemia (AML), acute lymphoid leukemia (ALL) and chronic myeloid leukemia (CML) after allogeneic hematopoietic stem cell transplantation. (globaldata.com)
Leukemia is either chronic or acute. (cancersupportcommunity.org)
Herrmann F, Komischke B, Odenwald E, Ludwig W. Use of monoclonal antibodies as a diagnostic tool in human leukemia, I: Acute myeloid leukemia and acute phase of chronic myeloid leukemia. (bdbiosciences.com)
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a myeloproliferative disorder characterized by increased proliferation of the granulocytic cell line without the loss of their capacity to differentiate. (medscape.com)
See Chronic Leukemias: 4 Cancers to Differentiate, a Critical Images slideshow, to help detect chronic leukemias and determine the specific type present. (medscape.com)
B19 has also been associated with fetal death (both spontaneous abortions and stillbirths), acute arthralgias and arthritis, and chronic anemia in immunodeficient patients (5-14). (cdc.gov)

2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. (qiagen.com)

4. Learn about the pathobiologic importance of epigenetic dysregulation in the development of acute myeloid leukemia and its clinical impact. (esh.org)
The myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic disorders characterized by cytopenias, dysplasia in one or more myeloid lineages, and the potential for development of acute myeloid leukemia. (jnccn.org)

Acute myeloid leukemia has a number of subtypes and precursor neoplasms that are distinguished from each other by morphology, immunophenotype, cytochemistry, and genetic abnormalities (see also The 2016 World Health Organization [WHO] Classification of myeloid neoplasms ) all of which have important implications for prognosis and treatment. (msdmanuals.com)
The fourth edition of the World Health Organization (WHO) classification of myeloid neoplasms refined the criteria for some previously described myeloid neoplasms and recognized several new entities based on recent elucidation of molecular pathogenesis, identification of new diagnostic and prognostic markers, and progress in clinical management. (nih.gov)
The NCCN Clinical Practice Guidelines in Oncology for MDS provide recommendations on the diagnostic evaluation and classification of MDS, risk evaluation according to established prognostic assessment tools (including the new revised International Prognostic Scoring System), treatment options according to risk categories, and management of related anemia. (jnccn.org)

Quest's expertise in molecular, infectious disease, and women's health diagnostics, and relationships with half of the country's physicians and hospitals, allow us to quickly make useful tests widely available for clinical use," Pesano added. (genomeweb.com)
Clinical trials are underway to find better ways of reducing symptoms and side effects of current leukemia treatments to improve comfort and quality of life for patients. (cancer.net)
QIAGEN's experienced regulatory teams will support clinical validation of the companion diagnostic and its approval in the US, the European Union and Japan. (servier.com)
The successful biannual ESH Conferences on acute myeloid leukemia (AML) have established themselves as scientific and educational programs at the interphase of molecular and biologic developments and clinical translation. (esh.org)
6. Gain insight into novel therapeutics of acute myeloid leukemia, including knowledge about their mechanisms of action, drug resistance mechanisms, the current developmental status of various targeted drugs and novel antibody-based and cell-transfer based immunotherapeutic approaches and their promises for future clinical application. (esh.org)
Now, research scientists at Virginia Commonwealth University (VCU) say they have developed a clinical laboratory diagnostic technique that could be far cheaper and more capable than standard DNA sequencing in diagnosing some diseases. (darkdaily.com)
Here are several abstracts selected from the proceedings of the 2016 ASCO Annual Meeting, focusing on clinical trials on therapeutics in different types of leukemia, multiple myeloma, follicular lymphoma, and central nervous system (CNS) lymphoma. (ascopost.com)
Once approved for clinical use, not only would these biomarkers become targets for specific cancer therapies, they also would require development of new diagnostic tests that anatomic pathologists could use to determine whether a biomarker was present in a patient. (darkdaily.com)
The Tumor Profiler Study is an observational clinical study combining a prospective diagnostic approach to assess the relevance of in-depth tumor profiling to support clinical decision-making ("fast diagnostic loop") with an exploratory approach to improve the biological understanding of disease ("exploratory science loop")," the TuPro website states. (darkdaily.com)
This research could lead to new precision medicine biomarkers for clinical laboratory cancer diagnostics and therapies. (darkdaily.com)
This approach has the potential to alter current diagnostics and paves the way for the translation of comprehensive molecular profiling into clinical decision-making," the study's authors wrote in Cancer Cell . (darkdaily.com)
Background: Whole-genome sequencing (WGS) and whole-transcriptome sequencing (WTS), with the ability to provide comprehensive genomic information, have become the focal point of research interest as novel techniques that can support precision diagnostics in routine clinical care of patients with various cancer types, including hematological malignancies. (lu.se)
Discussion: Data from this national multi-center study will be used to evaluate clinical performance of the integrated WGTS diagnostic workflow compared with standard of care. (lu.se)
Continuous updating of diagnostic and therapeutic strategies has not been effective in improving the clinical benefit of AML. (bvsalud.org)
Clinical Utility Of A Next-Generation Sequencing Panel For Acute Myeloid Leukemia Diagnostics. (cdc.gov)
He has published more than 110 scientific articles and many key findings have been translated into improved clinical diagnostics of leukemia and in the establishment of spin-out companies active in bioinformatics and in developing antibody-based therapies. (lu.se)
Acute myeloid leukemia (AML) is the most common acute leukemia in adults and is characterized by an aggressive clinical course and variable outcome due in part to clinical and biological heterogeneity. (medscape.com)

MPAL, mixed phenotype acute leukemia. (cancercentrum.se)

These discoveries help doctors better understand the causes of leukemia, determine the prognosis for each child, and even develop new drugs that target these specific genetic changes. (cancer.net)
DNA (cytosine-5)-methyltransferase 3A (DNMT3A)-mutated acute myeloid leukemia (AML) has a poor prognosis, but the exact mechanism is still unclear. (frontiersin.org)
Cancer researchers have linked these mutations, known as internal tandem duplications (ITDs), to a poor prognosis of acute myeloid leukemia (AML) and a more aggressive form of the disease, Nature Leukemia noted in " Targeting FLT3 Mutations in AML: Review of Current Knowledge and Evidence . (darkdaily.com)

To detect and type mutations in exon 4 of the IDH2 gene for differential diagnosis and prognostic stratification of glial tumors and acute myeloid leukemia. (mdanderson.org)
In the Swiss "Tumor Profiler" (TuPro) project, the research team is examining the cellular composition and biology of tumors of 240 patients with melanoma , ovarian cancer , and acute myeloid leukemia . (darkdaily.com)
The Childhood Solid Tumor Network and PROPEL support preclinical research into pediatric solid tumors and blood cancers such as leukemia. (stjude.org)
Results of WGS for tumor (90×) and normal/germline (30×) samples as well as WTS for tumors only will be compared to current standard of care diagnostics. (lu.se)

Objectives Acute myeloid leukemia (AML) is classified in part by recurrent cytogenetic abnormalities, often detected by both fluorescent in situ hybridization (FISH) and karyotype. (medscape.com)
It is common practice for laboratories to use interphase fluorescence in situ hybridization (FISH) panels in conjunction with karyotyping for the detection of the most prognostically significant recurrent AML-associated cytogenetic abnormalities, both in diagnostic specimens and during follow-up to monitor response to therapy. (medscape.com)

Treatment protocols for acute myeloid leukemia are provided below, including a general treatment approach and treatment recommendations for relapsed or refractory disease. (medscape.com)

Its AMLprofiler is a vitro diagnostic test that recognizes acute myeloid leukemia subtypes, and helps in making individualized therapy decisions. (researchandmarkets.com)

We discuss the value of lncRNAs as putative diagnostic, prognostic and therapeutic targets in myeloid leukemias and indicate novel directions in this exciting research field. (frontiersin.org)

SkylineDx BV (SkylineDx) is a developer and commercializer of gene signature-based diagnostic tests for personalized medicine in oncology. (researchandmarkets.com)

Paris (France), March 9, 2023 - Servier today announced it has entered into a strategic partnership with QIAGEN, a leading global provider of Sample to Insight solutions that enable customers to gain valuable molecular insights from samples containing the building blocks of life, to develop a companion diagnostic test that detects IDH1 mutations. (servier.com)
The American Cancer Society estimates that in the United States in 2023 there will be about 20,000 new cases of acute myeloid leukemia (AML) and about 11,300 deaths , almost all in adults. (msdmanuals.com)

Thus, this research may produce both diagnostic biomarkers and therapeutic targets. (darkdaily.com)
His research is focused on integrative genomic studies of acute leukemia, on functional/mechanistic studies of driver mutations, and on identifying new therapeutic targets on leukemia stem cells. (lu.se)

The cutting-edge program of the conference will deal with the molecular and functional features of leukemic stem cells and their interaction with the microenvironment, the role of somatic and germ-line mutations and epigenetic alterations in the biology of AML, the genomics of leukemogenesis, advances in molecular diagnostics and developmental therapeutics with a focus on molecular and immunotherapeutic targeted therapeutics. (esh.org)
I've been wondering lately: Are we perhaps in a new renaissance in health and healthcare, particularly as it relates to diagnostics and therapeutics for cancer, heart disease, obesity , and infectious disease? (medscape.com)

In acute myeloid leukemia (AML), malignant transformation and uncontrolled proliferation of an abnormally differentiated, long-lived myeloid progenitor cell results in high circulating numbers of immature blood cells and replacement of normal marrow by malignant cells. (msdmanuals.com)
Acute myeloid leukemia (AML) is a clonal hematopoietic neoplasm due to acquired oncogenic mutations that disrupts differentiation, resulting in the accumulation of immature myeloid blasts in the marrow. (utoronto.ca)

Early biomarker testing for an IDH1 mutation has grown in importance for targeted therapies and can play a critical role in the treatment of acute myeloid leukemia (AML). (servier.com)

Emergence of LSC is dependent on individual or combined genetic mutations that broadly determine the cellular affiliation of the leukemia, and permit or impose ectopic self-renewal and a restricted differentiation potential into what constitutes the proliferative bulk of the leukemia ( 5 , 6 ). (frontiersin.org)
QIAGEN and Servier are collaborating to develop a PCR-based companion diagnostic test that can be used to rapidly identify AML patients with IDH1 gene mutations. (servier.com)
The partnership with QIAGEN will lead to the development of a specific diagnostic test for IDH1 gene mutations with a rapid turnaround time. (servier.com)
Tefferi, A. and Pardanani, A. (2014) CALR mutations and a new diagnostic algorithm for MPN. (qiagen.com)
d Targeted Ampliseq is a polymerase chain reaction-based digital sequencing approach that allows for accurate determination of the frequency of specific mutations in acute myeloid leukemia samples. (jamanetwork.com)
Panels A through D show examples of different patterns of clearance of leukemia-associated mutations after induction therapy in 4 acute myeloid leukemia cases. (jamanetwork.com)

Akin to the normal hematopoietic system, leukemias are sustained by a small number of leukemia stem-like cells (LSC), which can be distinct from the normal hematopoietic stem cells (HSC) but also exhibit functional characteristics of self-renewal and (abnormal or hindered) differentiation, and are often quiescent ( 2 - 4 ). (frontiersin.org)
1. Understand the pathobiology of leukemia and its development with respect to alterations in hematopoietic stem cells, their microenvironment and altered signal transduction pathways. (esh.org)

The companion diagnostic will run on the QIAGEN Rotor-Gene Q MDx device, which is widely used by labs worldwide. (servier.com)
The first dataset was a gene-expression profile that characterizes the cancer cells of a group of acute myeloid leukemia patients. (biomedcentral.com)
Diagnostic Yield of Intellectual Disability Gene Panels. (cdc.gov)
If your health care provider thinks you may have a type of leukemia that involves the BCR-ABL1 gene , you may need a BCR-ABL1 genetic test to make a diagnosis. (medlineplus.gov)

At the same time, we are further strengthening our role in developing companion diagnostics for the ever-growing number of biomarkers being discovered in onco-hematology. (servier.com)

The study population consisted of 784 adults with acute myeloid leukemia in remission or myelodysplastic syndromes undergoing unrelated donor transplant reported to the Center for International Blood and Marrow Transplant Research. (haematologica.org)

T-cell large granular lymphocytic leukemia (T-LGLL) can present as a form of post-transplant lymphoproliferative disorder. (koreamed.org)
Investigating further, they determined a distinct overlap in expression patterns between infant AML and B-ALL (acute lymphocytic leukemia), a different form of acute leukemia. (fredhutch.org)

When you look at acute myeloid leukemia , today we have Flt3 inhibitors, IDH inhibitors. (medscape.com)

The cancer diagnostics market is on the verge of explosion, as the researchers approach major technological breakthroughs in tumor diagnosis and therapy, discover new specific antigens, and unlock the mystery of the genetic basis of the disease. (aarkstore.com)

All patient samples from the Ulm cohort were collected from adult patients enroled on German-Austrian AML Study Group (AMLSG) treatment protocols for younger adults (AMLSG-HD98A (NCT00146120) and AMLSG 07-04 (NCT00151242)) and comprised Ficoll gradient purified mononuclear cells mainly from diagnostic bm samples with blast counts of ~80% in all analyzed cases. (nature.com)
it is the most common acute leukemia in adults, with a median age of onset of 68 years. (msdmanuals.com)
Epidemiology of invasive fungal diseases in adults with newly diagnosed acute myeloid leukemia. (stanford.edu)
It accounts for 20% of all leukemias affecting adults. (medscape.com)
Diagnostic radiological examinations and risk of intracranial tumours in adults-findings from the Interphone Study. (who.int)

Many AML symptoms occur due to blood cell shortage, as leukemia cells crowd out healthy blood cells and prevent their production. (medicalnewstoday.com)
It aims to kill any remaining leukemia cells. (medicalnewstoday.com)
The genetics of leukemia cells are being tested to see if they can help doctors decide which patients may need more or less intense treatment. (cancer.net)
New methods to measure minimal residual disease (MRD) can find 1 leukemia cell in 10,000 healthy cells, which can help determine the likelihood of recurrence. (cancer.net)
The therapy comprises of T-cells genetically modified by lentiviral transduction to express TCR targeting the leukemia-associated minor H antigen, HA-1 and is administered as an intravenous infusion. (globaldata.com)
Leukemia is cancer of the blood cells. (cancersupportcommunity.org)
Leukemia is a group of cancers that develop in the cells that produce blood cells. (healthline.com)
Leukocyte Typing II: Human Myeloid and Hematopoietic Cells. (bdbiosciences.com)
Susceptibility of acute myeloid leukemia cells to ferroptosis and evasion strategies. (bvsalud.org)
RUNX1-positive leukemia cells in preclinical models. (lu.se)
These abnormal white blood cells are leukemia cells. (medlineplus.gov)

Bernstein ID, Self S. Joint report of the Myeloid Section of the Second International Workshop on Human Leukocyte Differentiation Antigens. (bdbiosciences.com)
Goyert SM, Ferrero E. Biochemical analysis of myeloid antigens and cDNA expression of gp55 (CD14). (bdbiosciences.com)

5. Evaluate the merits and relevance of molecular diagnostics and minimal residual disease assessment in relation to various management decisions. (esh.org)

Acute myeloid leukemia symptoms may be vague and resemble other common illnesses. (medicalnewstoday.com)
What are the general symptoms of acute myeloid leukemia? (medicalnewstoday.com)
Read on to learn about how APL differs from other leukemias, how to spot signs and symptoms, the diagnostic process, and how it's treated. (healthline.com)
The symptoms of APL tend to be nonspecific and can resemble those of many other conditions or other types of leukemia. (healthline.com)
You should consult a medical professional if you have any potential warning symptoms of APL, even if leukemia is unlikely to be the cause. (healthline.com)

The company offers MMprofiler and AMLprofiler molecular diagnostic tests for blood cancers. (researchandmarkets.com)

Acute myeloid leukemias (AMLs) are heterogeneous hematologic neoplasms characterized by myeloblast or promyelocyte proliferation without normal differentiation. (koreamed.org)

The ipsogen CALR RGQ PCR Kit is intended for in vitro diagnostic use. (qiagen.com)

Background: Application of the 2016 revised WHO criteria for categorization of acute myeloid leukemia (AML) highlights certain discrepancies from that of the 2008 WHO criteria. (koreamed.org)

Diagnostics, Imaging Agents, Biomarkers, stents and other drug delivery devices (covered in GlobalData's Medical Intelligence Center). (globaldata.com)
Particularly in cancer research, when reducing the number of features, i.e., genes, it is important to select the most informative features/potential biomarkers that could affect the diagnostic accuracy. (biomedcentral.com)

Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis. (thermofisher.com)
People who are exposed to high levels of radiation and the chemical benzene are more likely to get certain types of leukemia, as are smokers, people who have had chemotherapy and people with certain inherited diseases and blood disorders. (cancersupportcommunity.org)
Invasive fungal diseases (IFDs) are common in patients with acute myeloid leukemia (AML), but no recent data on incidence without antifungal prophylaxis are available. (stanford.edu)

The term 'therapy-related myeloid neoplasms' is used to cover the spectrum of disorders previously known as t-AML, t-MDS, or t-MDS/MPN occurring as complications of cytotoxic chemotherapy and/or radiation therapy. (nih.gov)

AML comprises about 25% of childhood leukemias, often developing in infancy. (msdmanuals.com)
Temporal changes of the incidence of childhood B-cell precursor acute lymphoblastic leukaemia in Germany during the COVID-19 pandemic. (who.int)

Therefore, this study analyzed the data of patients treated in three prospective trials of the "Study Alliance Leukemia" (SAL) study group for CNS involvement. (nih.gov)
In patients with risk factors, intense diagnostic and treatment strategies should be employed in the future. (nih.gov)
90% of reported cases is prolonged and profound neutropenia in patients with acute leukemia ( 6 , 7 , 9 ). (cdc.gov)
We are pleased to support Servier with a companion diagnostic in their mission to propose innovative treatment for IDH1 mutated AML patients. (servier.com)
Physicians should select advanced ovarian cancer patients for therapy based on a FDA-approved companion diagnostic. (merck.com)
Select patients for therapy based on an FDA-approved companion diagnostic for LYNPARZA. (merck.com)

a AML-RMG is a capture reagent consisting of all of the exons of the genes that are currently known to be recurrently mutated in acute myeloid leukemia, based on The Cancer Genome Atlas AML study. (jamanetwork.com)
Serial VAF measurements demonstrating the clearance patterns of several recurrently mutated acute myeloid leukemia genes in the set of 50 cases. (jamanetwork.com)
Particularly in cancer research, where data are obtained by microarrays, identifying "biomarker" genes can potentially improve diagnostic accuracy for applying individual therapeutic or preventive treatments [ 1 , 2 ]. (biomedcentral.com)

The subgroup 'acute myeloid leukemia (AML) with recurrent genetic abnormalities' has been expanded to include more molecular genetic aberrations. (nih.gov)

The availability of our new molecular Zika test provides physicians broad access to a diagnostic tool for managing the Zika outbreak," Rick Pesano, vice president of R&D for Quest Diagnostics, said in a statement. (genomeweb.com)

Today, the melanoma cohort is fully enrolled, and the ovarian cancer and acute myeloid leukemia cohorts are nearing complete enrollment. (darkdaily.com)

What are the treatments for acute myeloid leukemia? (medicalnewstoday.com)
This test will be for use with Servier's marketed and investigational targeted treatments in Acute Myeloid Leukemia (AML). (servier.com)
Before the development of modern medical treatments, APL had one of the poorest prognoses of all acute leukemias, and people usually died within a month . (healthline.com)

This new report from provides a strategic analysis of the major business opportunities emerging in the cancer diagnostics market during the next five years. (aarkstore.com)
During the next five years, the cancer diagnostics market is promising to be an exciting, dynamic and rapidly expanding field. (aarkstore.com)
More accurate but less-costly cancer diagnostics are the Holy Grail of cancer research. (darkdaily.com)

The assay, developed by the reference laboratory business of Quest's Focus Diagnostics subsidiary, is intended for the qualitative detection of Zika virus RNA in human serum specimens from certain individuals. (genomeweb.com)
Extensive listings of companies, universities and research centers developing new cancer diagnostic tests and detection technologies. (aarkstore.com)

Background: Exposures to DNA-damaging drugs and ionizing radiations increase risks of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). (houstonmethodist.org)

NEW YORK (GenomeWeb) - Quest Diagnostics said late on Thursday that it has received US Food and Drug Administration Emergency Use Authorization for the Zika Virus RNA Qualitative Real-Time RT-PCR test. (genomeweb.com)
The new assay can potentially be performed at any CLIA high-complexity laboratory in the Quest Diagnostics network, which includes several dozen labs in the US and Puerto Rico. (genomeweb.com)

Performance analysis of SiRe next-generation sequencing panel in diagnostic setting: focus on NSCLC routine samples. (cdc.gov)

Anatomy22

Organisms17

Diseases55

Chemicals and Drugs62

Analytical, Diagnostic and Therapeutic Techniques and Equipment65

Phenomena and Processes39

Disciplines and Occupations3

Information Science9

Named Groups1

Health Care22

Lymphoblastic Leukemia5

Bone marrow11

Promyelocytic leukemia3

Chronic6

Neoplasms and acute1

Development of acute myeloid2

Classification3

Clinical17

Mixed-phenotype acute leukemia1

Prognosis3

Tumors4

Cytogenetic abnormalities2

Refractory1

Subtypes1

Prognostic1

Oncology1

20232

Therapeutic targets2

Therapeutics2

Immature2

Treatment of acute1

Mutations6

Hematopoietic stem2

Gene4

Hematology1

Myelodysplastic syndromes1

Lymphocytic leukemia2

Flt31

Diagnosis1

Adults5

Cells11

Antigens2

Minimal residua1

Symptoms5

Cancers1

Hematologic1

Vitro diagnostic1

20161

Biomarkers2

Diseases3

Chemotherapy1

Childhood2

Patients6

Genes3

Recurrent1

Molecular1

Melanoma1

Treatments3

Cancer diagnostics3

Detection2

Syndrome1

Quest Diagnostics2

Sequencing1