Myelodysplastic SyndromesMyeloproliferative DisordersJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialSyndromeAnemia, RefractoryLeukemia, Myelomonocytic, ChronicReceptors, ThrombopoietinBone Marrow NeoplasmsAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteThrombocytosisLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeLeukemia, MyeloidBone MarrowMutationLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticChromosomes, Human, Pair 5Proto-Oncogene Proteins c-cblSplenomegalyHematologic NeoplasmsPrognosisHematopoietic Stem CellsAzacitidineKaryotypingLeukemia, Myelogenous, Chronic, BCR-ABL PositiveChromosome AberrationsLeukemiaDown SyndromeBlast CrisisPhiladelphia ChromosomeBone Marrow DiseasesHematologyTreatment OutcomeMonosomyDNA Mutational AnalysisPreleukemiaMyeloid Progenitor CellsJanus KinasesThalidomideChromosomes, Human, Pair 7Bone Marrow CellsMegakaryocyte Progenitor CellsMetabolic Syndrome XMegakaryocytesSTAT5 Transcription FactorDisease ProgressionAcute DiseaseMegakaryocyte-Erythroid Progenitor CellsMutation, MissenseCell Transformation, NeoplasticPancytopeniaAnemia, AplasticChromosome DeletionCytogenetic AnalysisNeoplasms, Second PrimaryClonal EvolutionAmino Acid SubstitutionMyelopoiesisPoint MutationRetrospective StudiesFusion Proteins, bcr-ablTrisomyGene Knock-In TechniquesHematopoietic Stem Cell TransplantationGranulocyte Precursor CellsAntineoplastic AgentsProtein Kinase InhibitorsCytogeneticsNeoplasmsHematopoiesisPhenotypeCase-Control StudiesProto-Oncogene ProteinsTranslocation, GeneticCohort StudiesAntimetabolites, AntineoplasticAntigens, CD34Polymerase Chain ReactionSurvival AnalysisChromosomes, Human, Pair 8Nephrotic SyndromeCell ProliferationErythropoietinBone Marrow ExaminationIn Situ Hybridization, FluorescenceExonsSjogren's SyndromeIron OverloadBlood Cell CountChromosomes, Human, Pair 20Fatal OutcomeSurvival RateErythrocyte TransfusionHematologic DiseasesRisk Factors