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Optic DiskOptic NerveOptic Disk DrusenOptic Nerve DiseasesGlaucomaRetinal Ganglion CellsRetinaOptic NeuritisOptic ChiasmOptic AtrophyOptic Nerve InjuriesOptic Lobe, NonmammalianOptic Neuropathy, IschemicOptic FlowOptics and PhotonicsOptic Nerve GliomaOptic Atrophies, HereditaryOptic Atrophy, Hereditary, LeberDelayed DiagnosisSensitivity and SpecificityPrenatal DiagnosisEarly DiagnosisDisk Diffusion Antimicrobial TestsOptic Atrophy, Autosomal DominantDiagnosisRetrospective StudiesPapilledemaFiber Optic TechnologyOphthalmoscopyMagnetic Resonance ImagingEyeSuperior ColliculiMicrobial Sensitivity TestsReproducibility of ResultsDiagnostic ErrorsVisual FieldsTomography, X-Ray ComputedAxonsIntraocular PressureNerve FibersTime FactorsPhotographyMesopic VisionEncyclopedias as TopicPhotoreceptor Cells, VertebrateVision, OcularLightRetinal Cone Photoreceptor Cells
RetinaGlaucomaEpisode of optic neuritisBeginning of the optic nerveOcularInflammation of the optic nerveNervesNeuritis usuallyClinicalBlood vesselsPapilledemaAtrophyDiseasesFibre-opticMiddle AgedToxic Optic NeurEtiologyRetrobulbar neuritisChiasmRetinal GanglMake an accurate diagnosisChoroidPeripapillaryPediatricVitreousNeuropathyBilateralDifferentialAcuteDiabetic retinopathyPathologyExaminationDiscVisualPaleTemporalRapid diagnosis and treatmentFindingsTreatmentDetectionRatioMultiple sclerosisMagneticBlindnessPatients
Retina14
Glaucoma18
  • Ruling out glaucoma in myopic eyes often poses a diagnostic challenge because of atypical optic disc morphology and visual field defects that can mimic glaucoma. (nih.gov)
  • We determined whether neuroretinal rim assessment based on Bruch's membrane opening (BMO), rather than conventional optic disc margin (DM)-based assessment or retinal nerve fiber layer (RNFL) thickness, yielded higher diagnostic accuracy in myopic patients with glaucoma. (nih.gov)
  • Myopic subjects with refraction error greater than -2 diopters (D) (spherical equivalent) and typical myopic optic disc morphology, with and without glaucoma, were recruited from a glaucoma clinic and a local optometry practice. (nih.gov)
  • The final classification of myopic glaucoma or myopic control was based on consensus assessment by 3 clinicians of visual fields and optic disc photographs. (nih.gov)
  • Bruch's membrane opening MRW is more sensitive than DM-RA and similar to RNFL thickness for the identification of glaucoma in myopic eyes and offers a valuable diagnostic tool for patients with glaucoma with myopic optic discs. (nih.gov)
  • It helps in the diagnosis of age-related macular degeneration, glaucoma, and optic nerve damages. (emergenresearch.com)
  • This ever-increasing incidence rate of glaucoma can be attributed to the delayed diagnosis of glaucoma due to its asymptomatic presentation. (docplexussolutions.com)
  • Pharma through its innovations can help in early and effective diagnosis of glaucoma by improving the QoL of patients. (docplexussolutions.com)
  • A recent article published in the review of ophthalmology states that gonioscopic examination is the gold standard for the diagnosis of primary closed-angle glaucoma (PCAG) . (docplexussolutions.com)
  • Perimetry or visual field examination forms the cornerstone for the diagnosis of primary open-angle glaucoma (POAG) . (docplexussolutions.com)
  • Thus in this regard, Pharma should consider guidelines, view of the medical community, and ease of disease diagnosis when innovating future medical devices for diagnosis of glaucoma. (docplexussolutions.com)
  • Optic nerve photography is also important for documenting and monitoring glaucoma. (medscape.com)
  • Computerized disk analysis and analysis of nerve-fiber layers has been gaining acceptance in the diagnosis and management of all forms of glaucoma. (medscape.com)
  • Because of its association with eye diseases such as myopia and glaucoma, PPA is an important indicator for diagnosis of these diseases. (duke.edu)
  • Glaucoma is a set of eye diseases that refers to damage of the optic nerve as a result of increased aqueous humor in the eye. (thefiftypluslife.com)
  • Although there is no cure to glaucoma, an early diagnosis can help prevent vision loss. (thefiftypluslife.com)
  • 40 years, ED aged ≥50 years, diabetes, family history of glaucoma, and/or preexisting diagnosis of glaucoma. (cdc.gov)
  • Recently, a novel neuroretinal rim parameter, based on the minimum rim width from Bruch's membrane opening to the neuroretinal surface (BMO-MRW), has demonstrated much greater effectiveness in evaluating the ONH for glaucoma than other optic disc margin measurements such as cup-to-disc ratio and rim area. (cdc.gov)
Episode of optic neuritis3
Beginning of the optic nerve1
Ocular4
  • The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules. (justia.com)
  • The present disclosure provides, at least in in part, methods and compositions for detecting and/or selectively targeting tumor cells, for example, for the diagnosis and/or treatment of cancer (e.g., ocular cancer). (justia.com)
  • The lines of force within the eye resulting from the pull of intrinsic and extrinsic ocular muscles on the relatively fixed site of the optic nerve have been studied. (medscape.com)
  • An ocular micrometer is a calibrated ruler etched on a glass disk that is used for measuring organisms under a microscope. (cdc.gov)
Inflammation of the optic nerve3
Nerves2
  • Optic neuritis is often a precursor of multiple sclerosis (MS), which is a chronic disease that results in damage and inflammation of the nerves of both the brain and spinal cord. (southeasternretinaspecialists.com)
  • Participants with normal optic nerves on exam received SDOCT of the optic nerve head (24 radial scans). (cdc.gov)
Neuritis usually2
Clinical9
  • The diagnosis is a clinical one, aided by information from temporal artery biopsies and, in some cases, MRI studies of the aorta and its primary branches. (hcplive.com)
  • The reason behind these varied sentiments was clinical pieces of evidence that showed that assessment of optic nerve (through OCT/ODP), along with perimetry provided complimentary clues for the diagnosis of POAG . (docplexussolutions.com)
  • Considering the above viewpoint of doctors, it can be said that when diagnosing a disease, doctors follow guidelines, consider the assessment ability of a diagnostic tool and at the same time use their clinical experience when confirming the diagnosis of a disease . (docplexussolutions.com)
  • The purpose of this study was to review the pathophysiology mechanisms and clinical features of arterial and venous thrombosis and to provide guidance for further research on the pathophysiological mechanism, clinical diagnosis, and treatment of venous thrombosis. (frontiersin.org)
  • The aim is to provide a reference for a comprehensive understanding of venous thrombosis and a scientific understanding of various pathophysiological mechanisms and clinical features related to venous thrombosis, which will contribute to understanding the pathogenesis of intravenous stroke and provide insight into diagnosis, treatment, and prevention. (frontiersin.org)
  • The clinical profile of optic neuritis: experience of the Optic Neuritis Treatment Trial. (bmj.com)
  • Prognosis is related directly to the clinical stage at diagnosis (See Prognosis ). (medscape.com)
  • The diagnosis of TBM cannot be made or excluded solely on the basis of clinical findings. (medscape.com)
  • Variable natural history and accompanying clinical features of TBM hinder the diagnosis. (medscape.com)
Blood vessels2
  • In addition to being the point where the optic nerve exits the eye, it is also where the major blood vessels enter to provide blood flow to the eye. (circat.cat)
  • If the blood vessels supplying the optic nerve become inflamed, it can lead to a condition called anterior ischemic optic neuropathy, which can cause sudden and permanent vision loss. (proprofs.com)
Papilledema1
Atrophy2
  • Current fundus examination of the right eye revealed pale optic disc, occluded retinal vessels, and diffuse chorioretinal atrophy (Fig. 2 ). (springeropen.com)
  • All patients had optic atrophy bilaterally, and all tested patients had visual field defects. (org.sa)
Diseases1
Fibre-optic4
  • Although the overlying neural tissue is partly transparent, and the accompanying glial cells have been shown to act as fibre-optic channels to transport photons directly to the photoreceptors, [7] [8] light scattering does occur. (wikipedia.org)
  • A new study by University of Toronto researchers offers the first-ever glimpse inside a laser while it's operating, a breakthrough that could lead to more powerful and efficient lasers for fibre-optic communication systems. (sciencedaily.com)
  • During the laser's operation, an electrical current flows into the chip, providing the energy to generate intense light at a specific wavelength used in fibre-optic communications. (sciencedaily.com)
  • Sargent says the findings could have larger implications for the creation of optical circuits for fibre-optic communication. (sciencedaily.com)
Middle Aged1
  • The coincidence of bilateral optic nerve damage and bilateral putaminal necrosis in a young or middle-aged male is very suspicious for methanol-induced damage. (org.sa)
Toxic Optic Neur1
  • But the most common situation occurs as isolated episodes, or epidemics of methanol poisoning and its toxic optic neuropathy, which are seen due to the contamination of handmade liquor, smuggled alcohol, and so forth with methyl alcohol. (org.sa)
Etiology1
  • This review summarizes the pathophysiological mechanisms, etiology, epidemiology, symptomatology, diagnosis, and treatment heterogeneity of venous thrombosis and compares it with arterial stroke. (frontiersin.org)
Retrobulbar neuritis3
  • Retrobulbar neuritis is a form of optic neuritis in which the optic nerve, which is at the back of the eye, becomes inflamed. (drugs.com)
  • In the early stages of retrobulbar neuritis, the optic disk appears normal. (drugs.com)
  • Optic neuritis (ON) may involve the retrobulbar (retrobulbar neuritis) or the intrabulbar (papillitis) portion of the optic nerve, or both. (bmj.com)
Chiasm1
  • The ophthalmic…, The medial rectus muscle is the largest of the eye's extraocular movement muscles, six individual muscles that surround the eye and help control the…, The optic chiasm or optic chiasma is an X-shaped space, located in the forebrain, directly in front of the hypothalamus. (circat.cat)
Retinal Gangl1
Make an accurate diagnosis1
  • To make an accurate diagnosis, it is necessary to visualize samples as clearly as possible. (cdc.gov)
Choroid1
  • Racial differences in the anatomy of the optic nerve head (ONH), such as larger optic discs and disc area, deeper cups, variation in lamina cribrosa position, and thicker overall retinal nerve fiber layer (RNFL) and peripapillary choroid thicknesses in AD individuals, have also been previously described. (cdc.gov)
Peripapillary1
  • The streaks intercommunicate in a ringlike fashion around the optic disc in 27% of cases and radiate outward in a tapering fashion from the peripapillary area in 73% of patients. (medscape.com)
Pediatric2
  • There are 2 main surgical approaches to the treatment of pediatric IIH: optic nerve sheath fenestration and CSF diversion (typically, lumboperitoneal shunting). (medscape.com)
  • Bilateral optic neuritis in pediatric systemic lupus erythematosus associated with antiphospholipid antibodies and neuromyelitis optica immunoglobulin. (psu.edu)
Vitreous1
  • The referring ophthalmologist confirmed the diagnosis of CMVR in the right eye after vitreous sampling and CMV PCR assessment. (springeropen.com)
Neuropathy2
  • The National Ethical and Research Com- optic neuropathy, that result in vision loss mittee of Oman approved this community- and blindness. (who.int)
  • Idiopathic ON, the most common form of ON, is an inflammatory optic neuropathy in the absence of evidence of a systemic inflammatory disease. (bmj.com)
Bilateral1
  • Methanol intoxication causes visual loss within 12-48 hours due to relatively severe, painless, bilateral optic nerve damage that may be somewhat variable between eyes, and is generally worse with advancing age. (org.sa)
Differential1
  • In the differential diagnosis, schwannoma and meningioma with pigmentation are to be considered as well. (wikipedia.org)
Acute1
  • TBM must be differentiated not only from other forms of acute and subacute meningitis, but also from conditions such as viral infections and cerebral abscesses (See Diagnosis ). (medscape.com)
Diabetic retinopathy2
  • The severity of this complication can lead to vision loss, creating an urgent need for early diagnosis and treatment of chronic diabetic retinopathy. (emergenresearch.com)
  • 3] S. W. Franklin and S. E. Rajan, 'Diagnosis of diabetic retinopathy by employing image processing technique to detect exudates in retinal images,' IET Image Processing, vol. 8, pp. 1-9, 2014. (jist.ir)
Pathology1
  • Given that the eye possesses clear optics and shares many neural and vascular similarities to the brain, it offers a direct window to cerebral pathology. (frontiersin.org)
Examination5
Disc4
  • Malignant transformation of optic disc melanocytoma? (wikipedia.org)
  • A doctor will use an ophthalmoscope or other specialized equipment (such as a slit lamp) to examine the back of the eye, particularly the optic disc. (drugs.com)
  • In order to eliminate optic disc and background noise in the fundus images, a simple preprocessing technique is introduced. (jist.ir)
  • When the optic cup becomes larger or the cup to disc ratio increases, the optic nerve can become damaged and result in loss of vision. (thefiftypluslife.com)
Visual5
Pale1
  • 9 however, the optic nerve gradually becomes pale within 30-60 days after ingestion. (org.sa)
Temporal1
  • Information from both temporal artery biopsies and MRI studies can assist in making the diagnosis. (hcplive.com)
Rapid diagnosis and treatment2
  • If untreated, TBM may have a poor outcome and permanent neurological sequelae, thus requiring rapid diagnosis and treatment. (medscape.com)
  • TBM is a very critical disease in terms of fatal outcome and permanent sequelae, requiring rapid diagnosis and treatment. (medscape.com)
Findings1
  • He says the findings could influence laser design, change the diagnosis of faulty lasers and potentially reduce manufacturing costs. (sciencedaily.com)
Treatment7
  • The growing incidence of retinal disorders across the glove, increased efficiency of diagnosis and treatment, and evolution of the retinal imaging systems are projected to propel the industry's growth over the coming years. (emergenresearch.com)
  • Jacksonville, FL area patients suffering from optic neuritis have numerous options for treatment regarding this common eye condition. (southeasternretinaspecialists.com)
  • Usually, optic neuritis resolves itself and requires no treatment. (southeasternretinaspecialists.com)
  • Healthline Media does not provide medical advice, diagnosis, or treatment. (circat.cat)
  • At present, the average survival from diagnosis to death is 4.6 years, affording little opportunity for treatment outside of palliative care. (frontiersin.org)
  • Prompt treatment is essential, as death or signfiicant neurological disability may occur as a result of missed diagnoses and delayed treatment. (medscape.com)
  • death may occur as a result of missed diagnoses and delayed treatment. (medscape.com)
Detection1
  • Diagnosis of ethylene glycol poisoning usually depends on the detection of the toxicant or toxic metabolites in serum or plasma. (cdc.gov)
Ratio1
Multiple sclerosis3
  • Between 20% and 40% of the 25,000 people who develop optic neuritis in the United States each year will develop multiple sclerosis within 5 years. (drugs.com)
  • Multiple sclerosis has also been shown to be a risk factor for developing optic neuritis since MS involves the immune system attacking the myelin sheath of the spinal cord and brain. (southeasternretinaspecialists.com)
  • Optic neuritis and multiple sclerosis. (bmj.com)
Magnetic1
  • Our state-of-the-art, on-site clean room allows us to efficiently and quickly address our customers damaged Hard Disk Drives (HDDs), Solid State Drives (SDDs), and RAID or NAS systems and recover magnetic, optic, and digital media. (carolinadatarecovery.com)
Blindness1
Patients6