Diagnosis of mesenchymal chondrosarcomas. Medical search. Frequent questions

There are three main types of bone sarcoma based on tissue type - an osteosarcoma, a Ewing's sarcoma, and a chondrosarcoma. (wikipedia.org)
Subtypes of chondrosarcomas have different features and different outlooks, they include:[citation needed] Dedifferentiated Dedifferentiated chondrosarcomas can change in part to cells that are like those of an osteosarcoma for example which has a faster rate of growth. (wikipedia.org)
A case of malignant mesenchymoma of the bladder containing leiomyosarcoma, rhabdomyosarcoma, chondrosarcoma, osteosarcoma, and myxomatous components is described. (biomedcentral.com)
Histopathologic diagnosis of the surgical piece: predominantly fibroblastic osteosarcoma of the maxillary sinus, Broders grade III-IV. (isciii.es)
Solid primary lesions of the hyoid bone are exceedingly rare and the reported cases have included plasmacytoma, osteosarcoma, giant cell tumor, aneurysmal bone cysts, osteoma, chondroma, and chondrosarcoma. (ajnr.org)
There are about 65 different subtypes of soft tissue sarcoma and three main subtypes of bone sarcoma: chondrosarcoma, osteosarcoma and ewing sarcoma. (denver7.com)
Osteosarcoma is a malignant mesenchymal tumor and is the most common primary bone tumor in dogs. (dogcancer.com)
With patients who present with locally advanced or metastatic chondrosarcoma, chordoma, or osteosarcoma, physicians should discuss the options surrounding deep-sequencing genomic tests, which may identify mutations that may be responsive to specific therapies and thus may guide referral to clinical trials. (medscape.com)

Mesenchymal chondrosarcoma (MC) must be differentiated from other malignant small cell tumors of bone and soft tissue . (webpathology.com)
The differential diagnosis of a malignant effusion is accordingly broad, especially for the small round blue cell tumors that includes not only mesenchymal tumors, but also non-mesenchymal tumors, such as neuroblastoma and Wilms tumor. (cytojournal.com)
The remaining sarcomas are made up of heterologous tumors-tumors that contain histologic components foreign to the uterus, such as rhabdomyosarcomas , osteosarcomas , and chondrosarcomas . (medscape.com)
Chondrosarcomas constitute approximately 11% of all primary bone tumors. (ajnr.org)

The histological features of mesenchymal chondrosarcoma was first described by Lichtenstein and Bernstein (1959), consist of primitive undifferentiated mesenchymal cells in which islands of cartilage are noted. (e-crt.org)
The tumor is composed of rich cellular and undifferentiated mesenchymal cells and well-differentiated cartilage. (e-crt.org)
Rhabdomyosarcoma is a neoplasm that develops from undifferentiated mesenchymal cells that have the capacity to differentiate into striated muscle. (reviewofophthalmology.com)

Ewing's sarcoma, and a chondrosarcoma. (wikipedia.org)
The cancer is different from the other sarcoma due to the presence of the unique myxoid chondrosarcoma. (healthadvicer.com)
Urinary bladder malignancy was suspected, and the differential diagnoses included urothelial cell carcinoma with blood clot, sarcoma, or other benign neoplastic mass. (biomedcentral.com)
Pathological examination led to a diagnosis of high-grade sarcoma composed of myofibrous differentiation, focal myxomatous pattern, and a few chondroid changes with marked nuclear atypia and increased mitotic figures (more than 10/10 high power field). (biomedcentral.com)
Sarcoma is a general term for a group of about 70 different types of cancers that start in mesenchymal cells, which are cells that develop into connective or lymphatic tissue and blood vessels. (denver7.com)
The average time between the radiation treatments and the diagnosis of a sarcoma is about 10 years. (denver7.com)
But if you're one of those people, a sarcoma or bone cancer diagnosis is life-changing. (mropa.com)
At Minneapolis Radiation Oncology, we understand the uncertainty that comes with a sarcoma or bone cancer diagnosis. (mropa.com)
We evaluated a cohort of 94 soft tissue sarcoma samples to assess the correlation between gene expression and protein expression by immunohistochemistry for endosialin and PDGFR- β , a reported interacting protein, across available diagnoses. (hindawi.com)
Within cohorts of soft tissue diagnoses assembled by tissue type (liposarcoma, leiomyosarcoma, undifferentiated sarcoma, and other), endosialin expression was significantly correlated with a better outcome. (hindawi.com)

Pneumoconioses: pathological findings and differential diagnosis, in particular silicosis and asbestosis. (unibo.it)
Granulomatous lung diseases: sarcoidosis and tuberculosis (and their differential diagnosis). (unibo.it)
Differential diagnosis of T2 hypointense masses in musculoskeletal MRI. (ocu-radiology.jp)
Review article: the differential diagnosis of bone marrow edema on wrist MRI. (ocu-radiology.jp)
A differential diagnosis of chondrosarcoma should be considered because of the life-threatening features of chondrosarcoma. (bvsalud.org)
The differential diagnosis also included infectious and neoplastic disorders such as cellulitis, primary bone lesions (benign or malignant), lymphoproliferative or vascular disorders, and secondary neoplasms including sinus-related lesions or distant metastases. (reviewofophthalmology.com)
With acquisition of these radiographic findings, a more complete and extensive bone-lesion differential diagnosis was drafted. (reviewofophthalmology.com)
Features and differential diagnosis of osteochondrolipoma are discussed. (sicot-j.org)

Primary retroperitoneal extraskeletal mesenchymal chondrosarcoma involving the vena cava: A case report. (docksci.com)
The current study presents a case of extraskeletal mesenchymal chondrosarcoma (ESMC) involving the vena cava that originally occurred in the retroperitoneum of a 61‑year‑old female. (docksci.com)
Extraskeletal mesenchymal chondrosarcoma (ESMC) may occur in any location that contains mesenchymal cells, however, the majority arise in the lower extremities (particularly the thigh), leptomeninges or the orbit (2). (docksci.com)

If the sample contains predominance of well-differentiated hyaline cartilage , it can be mistaken for conventional chondrosarcoma . (webpathology.com)
Radiographic features of MC also resemble those of conventional chondrosarcoma. (webpathology.com)
Mesenchymal chondrosarcomas are extremely rare in comparison to conventional chondrosarcomas and even more so when arising in an extraskeletal location. (docksci.com)
Conventional chondrosarcoma are further subdivided into grade I, grade II, and grade III. (abta.org)

Information from radiology, surgical, oncology and other clinical colleagues involved in the diagnosis and treatment of primary bone tumours should be properly assessed before undertaking a structured approach to specimen handling and histological reporting. (biomedcentral.com)
Small soft tissue masses indeterminate at imaging: histological diagnoses at a tertiary orthopedic oncology clinic. (ocu-radiology.jp)
Biopsy and histological examination by an experienced pathologist is mandatory for the final diagnosis. (jbstjournal.com)

A chondrosarcoma is the type of bone cancer that starts in the cartilage cells. (wikipedia.org)
The chondrosarcoma has cells producing cartilage. (healthadvicer.com)
Conventionally lipomas are composed of mature adipose tissue, but sometimes they can contain other mesenchymal elements such as fibrous tissue, blood vessels, and, less frequently, cartilage or bone. (sicot-j.org)
Chondrosarcoma , the second most common primary bone cancer, starts in cartilage cells. (mropa.com)
Chondrosarcoma is a malignant tumor involving the cells that produce cartilage matrix (the stuff cartilage is made from). (dogcancer.com)

It is also known as EMC (Extraskeletal Myxoid Chondrosarcoma). (healthadvicer.com)
We present the case of a periosteal, extraskeletal low grade myxoid chondrosarcoma of the ulna diaphysis. (openorthopaedicsjournal.com)

2008). This paper is about the macroscopic, surgical, radiological, and histopatholo-gical findings of chondrosarcoma in a cat. (ac.ir)
Surgical treatment may vary widely, based on an accurate diagnosis. (openorthopaedicsjournal.com)
The surgical therapy included an en-bloc resection with allograft reconstruction. (openorthopaedicsjournal.com)
Histopathologic study of the surgical piece revealed a malignant mesenchymal tumor of high cellular density arrayed in sheets and adopting different patterns in which fusiform, epithelioid, highly collagenized, and myxoid areas alternated. (isciii.es)
We present a case of chondrosarcoma of the hyoid bone with imaging, surgical, and pathologic correlation, and a review of the literature. (ajnr.org)
Accurate preoperative pathological diagnosis allows correct surgical planning and avoidance of reoperation. (hindawi.com)
Accurate preoperative pathological diagnosis allows correct surgical planning and avoidance of reoperation, either to achieve wider excision or for subsequent tumor recurrence [ 8 - 10 ]. (hindawi.com)
Diagnosis involves imaging techniques like X-rays, CT scans, MRIs, and surgical removal of loose bodies is the preferred treatment. (ijcmph.com)
Minimally invasive surgery soon expanded to extend beyond diagnosis and staging to surgical operations which previously had been performed as open procedures. (sarcomaoncology.com)
Standard treatment for chondrosarcoma is surgical removal, which may be followed by radiation therapy. (abta.org)

Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin and comprises the largest category of soft-tissue sarcomas both in children and adolescents. (biomedcentral.com)

Radiological examination could not identify primary soft tissue component in any localization at the time of diagnosis in either cases. (biomedcentral.com)
Malignant mesenchymoma, which was described by Stout in 1948, is defined as a malignant soft tissue tumor that consists of two or more distinctly different mesenchymal components in addition to fibrosarcomatous elements. (biomedcentral.com)
A 54-year-old woman was referred to the University Hospitals Leuven with the preliminary diagnosis of a soft tissue tumor in the right upper leg identified as a mass of 43 mm × 62 mm on plain radiograph and echography. (sicot-j.org)

Chondrosarcoma is an uncommon malignant neoplasm in which the neoplastic cells produce chondroid and fibrillar matrix (Durham, Popovitch, & Goldschmidt, 2008). (ac.ir)
Biopsy of the lesion demonstrated fibromyxoid to chondroid mesenchymal cells of unknown origin with no evidence of malign morphologic signs. (sicot-j.org)
The location beneath the mylohyoid muscles and the expansion of the hyoid bone with chondroid calcification should suggest the correct diagnosis. (ajnr.org)

A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer. (nih.gov)

Occasionally, imaging findings can suggest the correct diagnosis, but definitive diagnosis requires histologic evaluation of a representative biopsy specimen. (medscape.com)
Being familiar with the clinical and cytomorphologic features of these lesions, appropriately triaging the diagnostic material for ancillary testing, and correlating with radiologic findings are important in arriving at correct diagnoses and guiding management. (allenpress.com)
The diagnosis is made on the distinctive histologic characteristics and not on the clinical findings. (e-crt.org)
What is your diagnosis for the above findings? (cytojournal.com)
Mesenchymal chondrosarcoma: imaging features and clinical findings. (ocu-radiology.jp)

Destruhaut F, Dubuc A, Bos A. Diagnosis of Synovial Chondromatosis of Temporomandibular Joint: Case Report and Literature Review. (ijcmph.com)

Following excision of the masses, pathological examination confirmed a diagnosis of primary ESMC. (docksci.com)
Pathological diagnosis should be made according to the 2013 World Health Organization (WHO) classification. (medscape.com)

Radiation is occasionally used to try and prevent tumor recurrence, and chemotherapy is largely ineffective for this diagnosis. (sarctrials.org)
Chondrosarcoma may recur and may need treatment with surgery , chemotherapy or radiation . (wikidoc.org)
Mesenchymal chondrosarcomas can grow rapidly but respond to treatment with radiation and chemotherapy. (mropa.com)

Magnetic resonance imaging of trunk and extremity myxoid liposarcoma: diagnosis, staging, and response to treatment. (ocu-radiology.jp)

Complications that can develop as a result of chondrosarcoma are metastasis and recurrence. (wikidoc.org)
Follow up scans are extremely important for chondrosarcoma to make sure there has been no recurrence or metastasis . (wikidoc.org)

SC is a cartilaginous metaplasia of the mesenchymal remnants of the synovial tissue of the joints. (bvsalud.org)
The main cause is believed to be the metaplasia of embryonal mesenchymal tissue in the synovial membrane. (ijcmph.com)

The prognosis of chondrosarcoma correlates with the grade and stage of the lesion at the time of diagnosis . (wikidoc.org)
Also, the lack of high-grade squamous intraepithelial lesion which did not favor the diagnosis of SCC. (cytojournal.com)
The lesion may be present for a few weeks to a year before diagnosis. (msdmanuals.com)

Here, we report two challenging cases involving 17- and 9-years-olds males where diffuse and multiplex bone lesions suggested either a hematological disease or a primary bone tumor (mesenchymal chondrosarcoma). (biomedcentral.com)

Osteosarcomas are composed of mesenchymal cells that produce immature bone. (wikipedia.org)
Any of the mesenchymal elements present along the bone surface or the pluripotent cells found in the periosteum may give rise to these surface lesions. (openorthopaedicsjournal.com)
Pericytes and stromal fibroblasts derive from mesenchymal stem cells [ 3 ] and, as such, endosialin has been described as a mesenchymal marker. (hindawi.com)

Hence altogether, the final report concluded that carcinosarcoma is the most likely correct diagnosis. (cytojournal.com)
Besides a thorough patient history, imaging together with a biopsy is needed to establish a correct diagnosis. (openorthopaedicsjournal.com)
It was difficult and may be impossible to suggest the correct diagnosis by sonography. (ajnr.org)

Lipomas are the most common benign mesenchymal neoplasm in humans. (sicot-j.org)
Histopathologically, the neoplasm was composed of mature chondrocytes with minimal nuclear and cytoplasmic atypia compatible with grade I chondrosarcoma ( Fig 4 , Table ). (ajnr.org)

The mild chemotherapy drug imatinib shows some usefulness for this diagnosis, and SARC members consider it a standard of care for treatment of recurrences. (sarctrials.org)
It is not a substitute for diagnosis or treatment of any condition. (spineopedia.com)
As a condition of using the information on this website, Spineopedia.com and its physicians are not responsible for any advice, diagnosis, treatment or outcome you may obtain. (spineopedia.com)
Thus, incisional biopsy and histopathologic analysis are essential for final diagnosis and treatment planning. (ac.ir)
Correctly interpret the diagnoses of the pathologic conditions mentioned above, with a clear understanding of their value for the definition of patient prognosis and treatment. (unibo.it)
They selected a rare form of cancer, mesenchymal chondrosarcoma (MCS), which has not been well described and for which there is no effective treatment. (medindia.net)
AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. (medindia.net)
Dogs with intranasal chondrosarcomas may have better treatment responses than dogs with adenocarcinoma or squamous cell carcinoma 8 . (dogcancer.com)
Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment. (nih.gov)

Radiographic evaluation of OS of maxilla is important for diagnosis. (ac.ir)

Histopathology revealed grade 1 chondrosarcoma seen as mature chondrocytes with minimal nuclear and cytoplasmic atypia. (ajnr.org)

Chondrosarcoma is the rare type of bone cancer. (healthadvicer.com)

The preoperative diagnosis and proper management are crucial in phyllodes tumours because of their tendency to recur and malignant potential in some of these tumours. (hindawi.com)

Introduction Mesenchymal chondrosarcoma is a rare and aggressive variant subtype of chondrosarcoma, which represents ~1% of all chondrosarcomas. (docksci.com)

Clear cell Clear cell chondrosarcomas are rare, slow-growing, and seldom spread. (wikipedia.org)
Mesenchymal chondrosarcoma of the orbit is a exceedingly rare tumor. (e-crt.org)
Chondrosarcoma of the hyoid bone is rare. (ajnr.org)
Chondroma and chondrosarcoma are very rare. (abta.org)

Clear cell chondrosarcomas grow slowly. (mropa.com)

The tumor is composed of two cellular components: Epithelial and mesenchymal. (cytojournal.com)

Clear cell chondrosarcoma: 70% survival rate at 5 years. (wikidoc.org)
Dedifferentiated chondrosarcoma: 10% survival rate after 1 year. (wikidoc.org)
Early diagnosis and radical surgery are the keys to increasing survival rate. (ac.ir)

Cytologically the presence of both epithelial and stromal elements supports the diagnosis. (hindawi.com)

If your doctor suggests you have chondrosarcoma, then it means you have bone cancer. (healthadvicer.com)

It has relatively non-specific radiological appearance causing diagnostic challenges and may lead to erroneous diagnosis of a malignancy. (jbstjournal.com)

Unlike other cancers , chondrosarcoma can return many years later. (wikidoc.org)
While endometrial cancer affects reproductive age as well as postmenopausal women, 75% of endometrial cancers occur in postmenopausal women, with the mean age of diagnosis at 61 years. (medscape.com)

The value of FNAC in diagnosis of phyllodes tumour remains controversial, but core needle biopsy has high sensitivity and negative predictive value. (hindawi.com)

Chondrosarcomas are classified by grade as a measurement of their growth rate - I, II, and III. (wikipedia.org)

The use of ancillary studies including immunostaining, FISH, and molecular studies is thus often critical to reach a definitive diagnosis. (cytojournal.com)
The definitive diagnosis depends on histology. (bvsalud.org)

Most chondrosarcomas develop in the pelvis, legs or arms. (wikipedia.org)

Its diagnosis is a challenge to oral pathologists and is especially important in early stages to improve its prognosis. (ijofb.org)

Chondrosarcoma can rarely metastatize to skin. (wikidoc.org)

Diseases8

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes1

Anthropology, Education, Sociology and Social Phenomena1

Health Care1

Osteosarcoma8

Tumors4

Undifferentiated mesenchymal cells3

Sarcoma10

Differential8

Extraskeletal mesenchymal3

Conventional4

Histological3

Cartilage5

Myxoid chondrosarcoma2

Surgical10

Rhabdomyosarcoma1

Soft tissue3

Chondroid3

Prognostic1

Findings5

Synovial chondromatosis1

Pathological2

Radiation3

Liposarcoma1

Metastasis2

Metaplasia2

Lesion3

Primary1

Cells3

Correct diagnosis3

Neoplasm2

Treatment9

Radiographic1

Histopathology1

Type of bone1

Tumours1

Aggressive1

Rare4

Grow slowly1

Tumor is composed1

Survival rate3

Epithelial1

Bone Cancer1

Malignancy1

Cancers2

Biopsy1

Grade1

Definitive diagnosis2

Pelvis1

Prognosis1

Rarely1