• According to the records of the Department of Neurosurgery in Bielsko-Biała, 133 patients diagnosed with an intracranial meningioma confirmed by a histopathological test were operated in the last 10 years (2004-2014). (hindawi.com)
  • Ibebuike K, Ouma J, Gopal R. Meningiomas among intracranial neoplasms in Johannesburg, South Africa: prevalence, clinical observations and review of the literature. (medscape.com)
  • 18F-FDG PET in the assessment of tumor grade and prediction of tumor recurrence in intracranial meningioma. (medscape.com)
  • Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. (biomedcentral.com)
  • The three described cases demonstrate, that preoperative MRI and CT imaging is important for differential diagnosis to exclude intracranial connections of the tumors. (biomedcentral.com)
  • Meningiomas, craniopharyngiomas and gliomas are mainly intracranial lesions. (biomedcentral.com)
  • There was no evidence of a connection of this sinonasal meningioma to other intracranial masses, as indicated in CT scan in bone window and MR imaging (Fig. 2 ). (biomedcentral.com)
  • Spontaneous intracranial hemorrhage associated with an intracranial meningioma is rare, with a reported incidence of below 2.4% of all meningiomas. (bvsalud.org)
  • To evaluate the clinical, radiological and pathological properties of 56 patients diagnosed as intracranial meningioma between the years 1999 and 2010. (dergisi.org)
  • Due to the rapid developments of the diagnostic tests for intracranial meningiomas, it is getting easier to diagnose early and cure totally. (dergisi.org)
  • Meningiomas have an insidious clinical presentation with focal neurological findings (depending on location), seizures and signs of increased intracranial pressure. (neuropathology-web.org)
  • Meningioma comprises about one fourth of all primary tumors of the central nervous system (CNS). (medscape.com)
  • Anaplastic meningiomas often shed most of the obvious features of meningiomas, and their diagnosis may be difficult. (medscape.com)
  • In general, atypical meningiomas and anaplastic meningiomas comprise less than 10% of all meningiomas. (medscape.com)
  • Atypical and anaplastic meningiomas, however, show a male predominance. (medscape.com)
  • In the present work, we introduce a combination of mass spectrometry-based phosphoproteomics and peptide array kinomics to profile atypical and anaplastic (high-grade) meningiomas. (nature.com)
  • AKAP12 knockdown in benign meningioma cells SF4433 increases proliferation, cell cycle, migration, invasion, and confers an anaplastic profile. (nature.com)
  • Although most meningiomas are benign, 15-35% represents atypical or anaplastic forms 3 . (nature.com)
  • Anaplastic meningiomas lead to fatal outcomes despite surgery, radiation, and experimental medications. (nature.com)
  • A small proportion of meningiomas display overt cellular anaplasia and are classified as grade III (anaplastic or malignant meningioma) . (neuropathology-web.org)
  • Although meningiomas commonly arise in locations where meningothelial cells are found, the embryonic origin of intraventricular and pulmonary meningiomas are intriguing. (medscape.com)
  • Intraventricular meningiomas probably arise from the meningothelial cells of the tela choroidea, where there is an arachnoidal invagination into the stromal base of the choroid plexus. (medscape.com)
  • Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. (medscape.com)
  • Eom KS, Kim DW, Kim TY: Diffuse craniospinal metastases of intraventricular rhabdoid papillary meningioma with glial fibrillary acidic protein expression: a case report. (karger.com)
  • Although some of the observed variants, such as chondroid meningiomas, clear-cell meningiomas, papillary meningiomas, and rhabdoid meningiomas, are associated with unfavorable prognoses, the other histologic patterns are not indicators of unfavorable biologic behavior. (medscape.com)
  • Intracerebral cystic rhabdoid meningioma. (medscape.com)
  • Both rhabdoid and papillary meningioma are rare variants of meningioma categorized as WHO grade III. (karger.com)
  • Here, we report a rare case of combined rhabdoid papillary meningioma with discussion of its differential intraoperative cytologic diagnoses. (karger.com)
  • Rhabdoid papillary meningiomas, encountered less often, should be distinguished from metastatic tumors of rhabdoid or papillary configuration, astrocytomas, ependymomas and atypical teratoid/rhabdoid tumor. (karger.com)
  • We also emphasize that the present case is the first case of rhabdoid papillary meningioma with primary manifestation in the spinal cord. (karger.com)
  • Kepes JJ, Moral LA, Wilkinson SB, Abdullah A, Llena JF: Rhabdoid transformation of tumor cells in meningiomas: a histologic indication of increased proliferative activity: report of four cases. (karger.com)
  • Hojo H, Abe M: Rhabdoid papillary meningioma. (karger.com)
  • Al-Habib A, Lach B, Al Khani A: Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression. (karger.com)
  • Wakabayashi K, Suzuki N, Mori F, Kamada M, Hatanaka M: Rhabdoid cystic papillary meningioma with diffuse subarachnoid dissemination. (karger.com)
  • Wu YT, Ho JT, Lin YJ, Lin JW: Rhabdoid papillary meningioma: a clinicopathologic case series study. (karger.com)
  • Papillary meningioma: clinical and histopathological observations. (medscape.com)
  • The true diagnosis is based mainly on histopathological examination. (biomedcentral.com)
  • The histopathological diagnosis was a meningothelial meningioma corresponding to WHO grade I [ 3 ]. (biomedcentral.com)
  • Although the majority of meningiomas are benign, these tumors can grow slowly until they are very large, if left undiscovered, and, in some locations, can be severely disabling and life-threatening. (wanderluce.com)
  • The majority of meningiomas show loss of the entire chromosome 22 or 22q. (neuropathology-web.org)
  • In transitional meningiomas, tumor cells are arranged in whorls with hyalinized and calcified centers that are called psammoma (sand) bodies because they resemble tiny grains of sand. (neuropathology-web.org)
  • Developmental lesions such as heterotopia of meningothelial cells in the scalp are believed to be the origin of meningiomas under the scalp and skin of the head. (medscape.com)
  • With the exception that papillary meningiomas are more common in children, meningiomas are rather uncommon in children and almost never occur in infants. (medscape.com)
  • A tumor lesion was found with apoplexy, soft consistency, and violaceous color with abundant vascularity in the lesion's center, suggesting a probable angiomatous meningioma. (bvsalud.org)
  • Both non-neoplastic meningothelial cells and meningiomas possess mixed features of epithelial and mesenchymal cells. (medscape.com)
  • There are numerous subtypes of meningiomas, some of which demonstrate more a epithelial phenotype (e.g. microcystic, secretory, clear cell, chordoid, papillary) or more mesenchymal differentiation (e.g. fibrous, angiomatous, metaplastic)(Fletcher). (surgpath4u.com)
  • The differential diagnosis was an ONSM, a diffuse glioma of the optic nerve, or less likely, an atypical recurrence of pituitary adenoma. (drtimothysteel.com.au)
  • Most meningiomas (85-90 percent) are categorized as benign tumors, with the remaining 10-15 percent being atypical or malignant (cancerous). (wanderluce.com)
  • Over 40% of atypical meningiomas will reoccur after gross resection. (nature.com)
  • 15-20% of meningiomas are WHO grade II (atypical meningioma) . (neuropathology-web.org)
  • Atypical meningiomas grow more rapidly and are more prone to recur after surgical resection. (neuropathology-web.org)
  • Meningiomas are slow-growing tumors attached to the dura mater and are composed of neoplastic meningothelial cells. (wanderluce.com)
  • On gross examination, meningiomas may be attached to the dura, though they do not arise from the dura per se. (neuropathology-web.org)
  • Meningiomas , as defined by the 2016 World Health Organization (WHO), are "a group of mostly benign, slow-growing neoplasms that most likely derive from the meningothelial cells of the arachnoid layer. (medscape.com)
  • The unique structure of the tissue of this benign tumour, containing cells with cystic contents, causes interpretative difficulties already at the stage of an imaging diagnosis where the tumour needs to be differentiated from other intraosseous pathology. (hindawi.com)
  • An olfactory groove meningioma is a rare benign tumor with a rather insidious course. (symptoma.com)
  • Most meningiomas are benign. (medscape.com)
  • Meningioma tumors are often benign: You may not even need surgery. (wanderluce.com)
  • ICD-9-CM Diagnosis Code 225.2 : Benign neoplasm of cerebral meninges Free, official info about 2015 ICD-9-CM diagnosis code 225.2. (wanderluce.com)
  • Most meningiomas (80-85%) are benign (WHO grade I) and grow slowly. (neuropathology-web.org)
  • Body mass index, physical activity, and risk of adult meningioma and glioma: A meta-analysis. (medscape.com)
  • In all cases of intranasal or pharyngeal neoplasm the diagnosis of meningioma, craniopharyngeoma and glioma should be considered as differential diagnosis to optimize the surgical procedure. (biomedcentral.com)
  • In the 3 cases of anterior clinoidal meningioma, anterior clinoidectomy was performed easily and safely, and manipulation of the extended dural margin and origin dura mater was possible. (thejns.org)
  • Meningiomas , as defined by the World Health Organization (WHO), are "meningothelial (arachnoid) cell neoplasms, typically attached to the inner surface of the dura mater," and these tumors fall into WHO grades I, II, and III. (medscape.com)
  • The tumour is made up of specialized meningothelial cells that are normally attached to a part of the meninges called the dura. (mypathologyreport.ca)
  • Meningiomas are brain tumors that develop from the membrane (the "meninges") that covers the brain and spinal cord. (wanderluce.com)
  • Similar to other tumors, the risk factors for the development of meningiomas can be divided into those with clearly defined genetic etiology and those that are attributed to environmental and other nongenetic factors. (medscape.com)
  • The etiology of most meningiomas, however, remains unclear. (medscape.com)
  • 10.5137/1019-5149.JTN.9452-13.0 Extracranial meningiomas of the paranasal sinus are the rare tumors of unclear etiology. (turkishneurosurgery.org.tr)
  • This is the first report of the management of spheno-ethmoid sinus meningioma with the skull base surgery technique. (turkishneurosurgery.org.tr)
  • Abdel Kerim A, Bonneville F, Jean B, Cornu P, LeJean L, Chiras J. Balloon-assisted embolization of skull base meningioma with liquid embolic agent. (medscape.com)
  • Covering all aspects of skin disease from basic science through pathology and epidemiology to clinical practice, the text is recognized for its unparalleled coverage of diagnosis. (rooksdermatology.com)
  • Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. (beds.ac.uk)
  • abstract = "Background: Meningiomas are the most common tumor involving the cavernous sinus. (elsevierpure.com)
  • This strategy was used to better understand the underlying mechanisms of meningioma malignancy, aid in the development of novel therapies and markers of poor prognosis. (nature.com)
  • Loss of heterozygosity on chromosome 22q and 17p correlates with aggressiveness of meningiomas. (medscape.com)
  • These results demonstrate AKAP12 as a central regulator of meningioma aggressiveness with a possible role in progression. (nature.com)
  • To map the mechanisms of aggressiveness we aimed to investigate changes in protein phosphorylation across WHO grades of human meningiomas. (nature.com)
  • On the basis of imaging features and intraoperative findings, the tumor was diagnosed as primary extracranial meningioma of the sphenoethmoid sinus. (turkishneurosurgery.org.tr)
  • Conclusion: These findings suggest that in the case of cavernous sinus meningiomas with encasement and stenosis of the intracavernous ICA, invasion of the vessel wall has occurred. (elsevierpure.com)
  • The effect of these findings on the management of cavernous sinus meningiomas and the involved ICA is discussed. (elsevierpure.com)
  • Computed tomography (CT) scans confirmed the findings with the suspicion diagnosis of a frontal sinus mucocele. (biomedcentral.com)
  • Which MRI findings are characteristic of petrous apex meningioma? (wanderluce.com)
  • The histologic patterns and biologic spectrum of meningiomas partially reflect the aforementioned biologic functions and embryogenesis. (medscape.com)
  • In meningiomas, one feature may be dominant over the other, and this phenomenon partly contributes to the rich diversification of histologic patterns in these tumors. (medscape.com)
  • Some of the uncommon histologic patterns, such as the lymphoplasmacyte-rich meningioma, may raise concern for lymphoproliferative diseases. (medscape.com)
  • Patient demographic data, histologic diagnosis, and chondrosarcoma grade were recorded. (rsna.org)
  • The subtypes which most closely exhibits classic 'meningothelial' morphology are the meningotheliomatous (syncytial) and transitional (mixture of syncytial and fibrous subtypes) variants. (surgpath4u.com)
  • Histologically, meningiotheliomatous meningioma is composed of whorls of cells separated by a fibrous stroma. (surgpath4u.com)
  • According to our own records, out of 14 cases of the bone tumours of the calvaria operated in the period from January 2004 to February 2014 at our Department of Neurosurgery, meningiomas constituted 21% of the cases. (hindawi.com)
  • Pieper DR, Al-Mefty O, Hanada Y, Buechner D. Hyperostosis associated with meningioma of the cranial base: secondary changes or tumor invasion. (medscape.com)
  • Meningothelial meningiomas are composed of diffuse masses of arachnoidal-like cells. (neuropathology-web.org)
  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. (beds.ac.uk)
  • The following study presents the case of a microcystic meningioma found in a 59-year-old woman who underwent a successful surgical treatment. (hindawi.com)
  • Majchrzak K, Tymowski M. Surgical treatment of the tentorial and falco-tentorial junction meningiomas. (medscape.com)
  • With her symptoms progressing and the uncertainty of the diagnosis, the patient expressed a strong preference for surgical exploration and removal of the lesion with division of the optic nerve. (drtimothysteel.com.au)
  • Ideally, surgical removal of meningioma entails removal of a one-centimeter margin all the way around the tumor. (wanderluce.com)
  • Search for eosinophilic hyaline cytoplasm, rather than a fibrillary one, is critical for distinguishing it from other commonly encountered spinal cord tumors in the total absence of meningothelial whorls, like the present case. (karger.com)
  • Fibroblastic meningiomas are composed of fascicles of fiber-like cells with abundant interstitial collagen. (neuropathology-web.org)
  • Meningiomas, especially of the fibroblastic type, are one of the BT seen in BANF. (neuropathology-web.org)
  • Most patients are asymptomatic, with the diagnosis often established after an incidental finding or with pain, swelling, or fracture. (wikipedia.org)
  • Meningiomas are a diverse set of tumors arising from the meninges, the membranous layers surrounding the central nervous system….The ICD code D32 is used to code Meningioma. (wanderluce.com)
  • We describe the case of a 55-year-old woman with subdural hemorrhage over the frontoparietal region of the right hemisphere associated with a meningioma, generating a mass effect and shifting the third ventricle and lateral ventricle. (bvsalud.org)
  • No subdural involvement of the meningioma was seen at either end of the nerve segment. (drtimothysteel.com.au)
  • A definitive diagnosis requires specialized immunohistochemical examinations. (biomedcentral.com)
  • This would also explain the high incidence of meningiomas around the sagittal sinus, which has a high concentration of meningothelial cells. (medscape.com)
  • The overall incidence of meningioma in Norway is 1.5 per 100,000 population among men and 2.8 in women. (medscape.com)
  • Meningioma is essentially a tumor of adulthood, with a peak incidence in the sixth decade of life. (medscape.com)
  • With the close resemblance between meningiomas and meningothelial cells, these cells are believed to be the cell of origin of meningiomas. (medscape.com)
  • [ 4 , 5 ] are small perivascular nodules that are histologically and ultrastructurally identical to meningothelial cells of the CNS. (medscape.com)
  • The meningothelial cells do not invade the pial/arachnoid tissue. (drtimothysteel.com.au)
  • The authors evaluate the extent of carotid wall involvement in nine patients with cavernous sinus meningiomas encasing the ICA who underwent en bloc resection of the cavernous sinus. (elsevierpure.com)
  • Differentially regulated pathways were characteristic of high-grade meningiomas. (nature.com)
  • Meningiomas also express female sex hormone receptors, explaining their rapid growth during pregnancy. (neuropathology-web.org)
  • Although these tumors have been known to invade adjacent structures such as bone, soft tissue, and brain, invasion of the internal carotid artery (ICA) by meningiomas has only been recognized recently. (elsevierpure.com)
  • Meningiomas located inside the bone of the calvaria belong to the group of rare types of tumours. (hindawi.com)
  • Only one variant of microcystic meningioma was located inside the bone, which constitutes 0.75% of all the meningiomas operated. (hindawi.com)
  • The microcystic variant of meningioma located inside the bone of the calvaria is very rare [ 2 , 3 ]. (hindawi.com)
  • [ 6 ] Patients with multiple meningiomas generally comprise less than 10% of cases. (medscape.com)