• Neuro-oncology is the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life-threatening (astrocytoma, glioma, glioblastoma multiforme, ependymoma, pontine glioma, and brain stem tumors are among the many examples of these). (wikipedia.org)
  • Primary brain tumors can occur at any age, from infancy to late in life. (wikipedia.org)
  • Most types of primary brain tumors are more common in men with the exception of meningiomas, which are more common in women. (wikipedia.org)
  • The rapid growth of fast-growing high-grade brain tumors may damage the subcortical network essential for electrical transmission, whereas slow-growing tumors have been suggested to induce partial deafferentation of cortical regions, causing denervation hypersensitivity and producing an epileptogenic milieu. (wikipedia.org)
  • 1. Brain Tumor Presentations In general, patients with primary brain tumors or single metastatic tumors can present with any of these signs and symptoms, whereas patients with multiple brain metastases tend to present with generalized symptoms and may lack localized findings. (wikipedia.org)
  • A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (lookformedical.com)
  • Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. (lookformedical.com)
  • A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes. (lookformedical.com)
  • Brain tumors may be congenital in children younger than 3 years of age and range from benign complex lesions to highly malignant neoplasms. (medlink.com)
  • In contrast to medulloblastomas, which by definition originate from the cerebellum or dorsal brainstem, other CNS embryonal tumors may arise across the neuraxis. (medlink.com)
  • In this article, the authors provide an overview of current concepts of clinicopathologic characteristics, specific molecular diagnosis, and general treatment strategies for these rare embryonal tumors of childhood. (medlink.com)
  • The common embryonal brain tumor medulloblastoma and the rare atypical rhabdoid teratoid tumor are well-defined entities in terms of their histopathological features, immunophenotype, and genetic profiles, as are other brain tumors occurring in this age range, including choroid plexus tumors and infant gliomas, and they are discussed in separate articles. (medlink.com)
  • Although uncommon in children younger than 2 years of age, primary CNS tumors at this age comprise almost 15% of all childhood brain tumors. (medlink.com)
  • They can present as large tumors occupying contiguous cerebral lobes or as primary pineal, brainstem, or spinal cord tumors. (medlink.com)
  • Tumors of the cranial nerve sheath constitute 5% to 10% of all intracranial neoplasms, yet few articles have described their CT and MR characteristics. (ajnr.org)
  • On unenhanced CT scans, tumors were isodense with brain in six patients and hypodense in two. (ajnr.org)
  • Cranial nerve sheath tumors constitute 5% to 10% of all intracranial neoplasms. (ajnr.org)
  • Metastatic malignant tumors of the temporal bone are relatively uncommon. (ejao.org)
  • The Utility of Whole Body Imaging in the Evaluation of Solitary Brain Tumors. (beds.ac.uk)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
  • This theory holds that tumors arise from 1 of 2 undifferentiated stem cells: the excretory duct reserve cell or the intercalated duct reserve cell. (medscape.com)
  • Childhood extracranial germ cell tumors form from germ cells in parts of the body other than the brain. (cigna.com)
  • This summary is about germ cell tumors that form in parts of the body that are extracranial (outside the brain). (cigna.com)
  • For information on intracranial (inside the brain) germ cell tumors, see Childhood Central Nervous System Germ Cell Tumors Treatment. (cigna.com)
  • Childhood extracranial germ cell tumors may be benign or malignant. (cigna.com)
  • Malignant extracranial germ cell tumors are tumors that form outside the brain. (cigna.com)
  • Extragonadal extracranial germ cell tumors form in areas of the body other than the brain or gonads (testicles and ovaries). (cigna.com)
  • Surgery may in some cases be curative, but, as a general rule, malignant brain cancers tend to regenerate and emerge from remission easily, especially highly malignant cases. (wikipedia.org)
  • Among such inhibitors Vemurafenib, a competitive small molecule that selectively recognizes the ATP binding domain of the BRAFV600E mutant, has proved effective in the treatment of metastatic melanoma, a neoplasm frequently mutated for BRAF. (biomedcentral.com)
  • When a known cancer patient whose primary disease is controlled presents with otologic symptoms and a history of chronic mastoid infection, metastatic carcinoma of the temporal bone must be considered as an uncommon, but possible diagnosis. (ejao.org)
  • Knowledge of imaging characteristics of various mesenteric lesions helps in timely diagnosis and management. (sajr.org.za)
  • Understanding the characteristic radiological patterns on ultrasound (USG) and CT offers valuable insights for differential diagnoses of mesenteric lesions and their treatment. (sajr.org.za)
  • Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. (medscape.com)
  • There are three types of intracranial metastasis: brain metastasis, dural metastasis, and leptomeningeal metastasis. (wikipedia.org)
  • A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. (lookformedical.com)
  • Overview of Myeloproliferative Neoplasms Myeloproliferative neoplasms are clonal proliferations of bone marrow stem cells, which can manifest as an increased number of platelets, red blood cells (RBCs), or white blood cells (WBCs). (msdmanuals.com)
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • Among the malignant brain cancers, gliomas of the brainstem and pons, glioblastoma multiforme, and high-grade (highly anaplastic) astrocytoma/oligodendroglioma are among the worst. (wikipedia.org)
  • Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. (lookformedical.com)
  • Note: Pilocytic/juvenile astrocytoma M-9421 moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3. (cancer.gov)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • In cases involving pre-existing middle ear diseases, correct diagnosis is even more difficult. (ejao.org)
  • Some mesenteric diseases present with distinctive imaging findings while others have similar findings, thereby complicating their differential diagnosis. (sajr.org.za)
  • Experience in the SEER registries has shown that using the Supplemental List increases casefinding for benign brain and CNS, hematopoietic neoplasms, and other reportable diseases. (cancer.gov)
  • CT plays an essential role in the diagnosis of mesenteric disease. (sajr.org.za)
  • The results of a multiorgan workup performed at the time of diagnosis were predictive of which patients in this cohort manifested multisystem disease. (thedoctorsdoctor.com)
  • It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
  • Factors such as age, tumor location, and clinical presentation are helpful in differential diagnosis. (wikipedia.org)
  • 4 Differential diagnosis includes desmoid tumour and solitary fibrous tumour. (sajr.org.za)
  • Under the initial suspicion of a facial nerve complication stemming from chronic mastoiditis, a computed tomography (CT) of temporal bone was taken. (ejao.org)
  • Some clinical correlation is made, and differential diagnoses are discussed. (ajnr.org)
  • Brain metastasis can be single or multiple and involve any portion of the brain. (wikipedia.org)
  • The average age of the patients was 36 years (range, 19-63 years) at the time of diagnosis. (ajnr.org)
  • A multiorgan evaluation at the time of diagnosis may be predictive of the probability of multisystem involvement with LCH. (thedoctorsdoctor.com)
  • Medulloblastoma is the most common embryonal brain tumor, whereas other embryonal tumor types are considered "rare" and typically affect infants and very young children. (medlink.com)
  • Manifestations typically include those of brain or lung hypoxia (eg, encephalopathy, dyspnea, respiratory failure). (msdmanuals.com)
  • Secondary involvement of the mesentery from tumours elsewhere is much more common than primary mesenteric neoplasms such as desmoid tumour, inflammatory myofibroblastic tumour (IMFT), and others. (sajr.org.za)
  • Dural metastases can invade the underlying brain and cause focal edema and associated neurologic symptoms. (wikipedia.org)
  • Symptoms of hearing loss, vertigo, facial nerve paralysis, and tinnitus overlap those of chronic mastoiditis, and correct diagnosis may be delayed. (ejao.org)
  • Overview of Leukemia Leukemia is a malignant condition involving the excess production of immature or abnormal leukocytes, which eventually suppresses the production of normal blood cells and results in symptoms. (msdmanuals.com)
  • Recent advances in the molecular diagnosis and treatment of pineoblastoma, a rare embryonal tumor of the pineal gland with particular penetrance in infants and young children, are also highlighted in this review. (medlink.com)
  • Imaging helps in the diagnosis of these tumours and aids in directing appropriate treatment by assessing their size, extent and relationship with adjacent structures. (sajr.org.za)
  • WTC Health Program member benefits include periodic medical monitoring, diagnosis, and treatment for qualifying health conditions. (cdc.gov)
  • We retrospectively studied the imaging findings in nine patients (seven women and two men) with a diagnosis of schwannoma of the jugular foramen referred to our institution from 1984 to 1996. (ajnr.org)
  • In these cases, untreated survival usually amounts to only a few months, and survival with current radiation and chemotherapy treatments may extend that time from around a year to a year and a half, possibly two or more, depending on the patient's condition, immune function, treatments used, and the specific type of malignant brain neoplasm. (wikipedia.org)
  • However, SEER registries will CONTINUE to report these cases and code behavior as /3 (malignant). (cancer.gov)
  • Although primary neoplasms arising in the mesentery are rare, the mesentery is a major avenue for the dissemination of tumours, which can spread through hematogenous, lymphatic, direct or peritoneal seeding. (sajr.org.za)
  • Primary mesenteric solid neoplasms are rare and the majority of them are benign. (sajr.org.za)
  • Salivary gland neoplasms are rare in children. (medscape.com)
  • The histological examination of the residual lesion showed the presence, in addition to the glial component, of mature ganglion cells, leading to a diagnosis of ganglioglioma (GG) (Figure 2 ) with classical morphology, i.e. neoplastic astrocytes and ganglion cells with dysplastic, binucleated neuron, embedded in tissue with eosinhophilic granular body and lymphocytic intratumoral infiltrate. (biomedcentral.com)
  • A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. (lookformedical.com)
  • RESULTS: The median age at diagnosis of LCH was 1.8 years (range 0.1 to 14.6 years). (thedoctorsdoctor.com)
  • Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. (lookformedical.com)
  • Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
  • Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (lookformedical.com)
  • A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. (lookformedical.com)
  • Unspecified/other malignant neoplasm of skin of upper limb, incl. (cancer.gov)