Diagnosis of lassa fever. Medical search. Frequent questions

Nigeria is experiencing a smoldering Lassa fever outbreak. (upr.org)
The Lassa outbreak reveals a few inherent cracks in Nigeria's system and raises good lessons in determining how a country or region can best respond to emerging infections. (upr.org)
It was piloted using a Lassa fever (LF) outbreak scenario. (biomedcentral.com)
Patient with Ebola hemorrhagic fever during 1976 outbreak in Zaire demonstrating palatal petechiae and hemorrhage. (medscape.com)
An outbreak of Lassa fever in Nigeria has infected more than 350 people since January. (buzzfeednews.com)
During the 2018 Lassa fever outbreak in Nigeria, samples from patients with suspected Lassa fever but negative Lassa virus PCR results were processed through custom gene expression array cards and metagenomic sequencing. (cdc.gov)
During January–December 2017, state health departments across Nigeria collected a total of 160 samples according to Nigeria’s National Lassa Fever Outbreak Guidance for patients who met the case definition for Lassa fever (V. Navapurkar et al. (cdc.gov)
The statement said that NCDC had dispatched a team of epidemiologists to support Ogun State to respond to the recent outbreak where a case of Lassa fever was confirmed in a healthcare worker, who died later at the Federal Medical Centre, Abeokuta. (naijanews.com)
Throughout the dry season, a new communication plan would address priority antecedents of Lassa Fever outbreak to ensure prevention is guaranteed," he said. (naijanews.com)
The World Health Organisation (WHO) says that with declining numbers and only a handful of confirmed cases reported in recent weeks, the critical phase of Nigeria's largest Lassa fever outbreak is under control. (environewsnigeria.com)
These figures, according to WHO compare with earlier reports issued in January, the beginning of the outbreak, to Feb. 18, when the number of weekly reported Lassa fever cases increased from 10 to 70. (environewsnigeria.com)
He has provided management support for immunization activities across several states in Nigeria and has been involved in several epidemiological studies including investigation of Lassa fever outbreak (2016), Measles Outbreak (2012 to 2015) Evaluation of Acute Flaccid Paralysis (AFP) Surveillance System in (2012 to 2017), Quality Assessment of Malaria Microscopy among Laboratory Personnel and Suppliers (2018), and Retrospective Investigation of Monkeypox Outbreak in Lagos State, Nigeria (2019). (onehealthdev.org)
Cases of deaths arising from fresh outbreak of Lassa fever this year have risen to no fewer than 41across the country as at Jan. 28, 2020 and has continued to rise by the day. (com.ng)
The current outbreak of the viral disease, Lassa fever, in Nigeria has resulted in some 53 fatalities in 10 states and the Federal Capital Territory (FCT) since December, according to UN health officials Friday. (outbreaknewstoday.com)
Lassa fever outbreak is a yearly occurrence during the dry season in Nigeria but, this year's outbreak is more widespread with 10 states, 140 suspected and 30 confirmed cases. (outbreaknewstoday.com)
Pingback: Nigeria News Today: Lassa outbreak grows, Adewole points fingers? (outbreaknewstoday.com)
An outbreak of Lassa fever was declared in Nigeria on the 21st of January 2019. (nigeriahealthwatch.com)
Following the large Lassa fever outbreak in 2018, the NCDC together with partners instituted five key measures to ensure improved preparedness in 2019. (nigeriahealthwatch.com)
The progress recorded in the response to the 2019 Lassa fever outbreak including an early decline in the number of new cases and reduced case fatality have been attributed to various factors. (nigeriahealthwatch.com)
While the number of new Lassa fever cases have significantly reduced over the past weeks, intensified response activities are on-going to control the outbreak across Nigeria. (icanetwork.co.za)
As at 24 February, Bauchi, Gombe and Taraba have notably reported more cases (29, 24 and 03 cases respectively) than in 2018 during the worst Lassa fever outbreak to date. (icanetwork.co.za)
The medical researcher spoke on the outbreak of Lassa fever in Lagos State following which two persons have been confirmed dead. (politicsgovernance.com)
Iwalokun said that the major gap in the nation's health system was the low level of preparedness, which according to him, contributed to the constant outbreak of Lassa fever yearly in the country. (politicsgovernance.com)
We need to strengthen our clinical practices in all the health facilities by training the health personnel on how to handle emergency cases to reduce the delay in diagnosis and treatment of any outbreak," Iwalokun said. (politicsgovernance.com)
The Field under the agreement is the diagnosis, prevention and treatment of infections caused by pathogens on the WHO R&D blueprint priority list , Chikungunya, Lassa Fever and any novel or previously unrecognized pathogen likely to result in an Outbreak. (ghiaa.org)
Ebola virus disease outbreak occurred in 2014 in Liberia, Guinea and Sierra Leone, Monkeypox virus in Nigeria in 2017 and most recently Lassa virus in Nigeria, Togo and Benin in 2018. (who.int)

Lassa fever , also known as Lassa hemorrhagic fever (LHF) , is a viral hemorrhagic fever caused by the Lassa virus , which has been identified in parts of West Africa. (highratedgabru.com)
Lassa fever is relatively common in West Africa including the countries of Nigeria, Liberia, Sierra Leone, Guinea, and Ghana. (wikipedia.org)
That diagnosis allowed the mobilization of a public health infrastructure, which is much stronger than other countries in West Africa due to the investment made as part of the campaign to eradicate polio over the past 20 years. (upr.org)
Even when severe, they overlap with many diseases that are common in West Africa, including malaria, cholera, and Lassa fever . (vectorsjournal.org)
There are Lassa fever outbreaks every year in Nigeria, typically between the months of December and May, and the disease is endemic to West Africa, according to Dr. Pierre Rollin, an expert in hemorrhagic diseases at the US Centers for Disease Control and Prevention (CDC). (buzzfeednews.com)
The reservoir for the virus is a rodent that exists all over West Africa [multimammate rat], and it's chronically infected with Lassa all year," Rollin says. (buzzfeednews.com)
Lassa fever is endemic in West Africa and has been reported from Sierra Leone, Guinea, Liberia, and Nigeria. (folkhalsomyndigheten.se)
Studies reported in English, that investigated Lassa fever with reference to West Africa were identified using the Medline Entrez-PubMed search and were used for this review. (folkhalsomyndigheten.se)
Lassa fe- Lassa virus in many more districts and states in en- ver is endemic in West Africa and has been reported demic countries of the West African sub-region and from Sierra Leone, Guinea, Liberia, and Nigeria4-7. (folkhalsomyndigheten.se)
Lassa reported in English, that investigated Lassa fever with virus is spherical in shape and measures between 70 reference to West Africa were identified using the and 150 nm in diameter (Fig. 1). (folkhalsomyndigheten.se)
Combinations of face envelope with T-shaped spikes measuring 7-10 key words such as Lassa fever and West Africa were nm and built with glycoprotein. (folkhalsomyndigheten.se)
Lassa Fever is endemic in most parts of West Africa most especially Sierra Leone, Liberia, Guinea, and Nigeria. (helpinitiative.org)
Every year the number of reported Lassa virus infections in West Africa is estimated at 100,000 to 300,000, with approximately 5,000 deaths. (helpinitiative.org)
Lassa fever is a major public health challenge in West Africa, with Nigeria bearing the highest burden. (gov.ng)
Lassa fever, an acute viral disease that occurs in West Africa was first discovered in 1969 when two missionary nurses died in Lassa village in Borno. (com.ng)
I have been working in the space of infection diseases in the past 22 years, across West Africa and on Lassa fever, Ebola, monkey pox, yellow fever and coronavirus. (infactng.com)
Lassa fever is also endemic in certain areas of West Africa and may show symptoms similar to early EVD. (blogspot.com)

A diagnosis of Lassa fever can be difficult because the symptoms are similar to those of other diseases, such as malaria. (highratedgabru.com)
Other conditions that may present similarly include Ebola, malaria, typhoid fever, and yellow fever. (wikipedia.org)
Early symptoms include fever, headache, and sore throat so it's often confused with the most prevalent disease in tropical areas: Malaria," Rollin says. (buzzfeednews.com)
The early stages of Lassa fever present initially like other febrile illness such as malaria. (gov.ng)
Remember, not all fevers are due to malaria. (gov.ng)
Any febrile illness that has not responded to 48 hours use of anti-malaria or antibiotics should raise an index of suspicion for Lassa fever! (gov.ng)
Lassa fever presents initially like any other febrile illness such as malaria. (hsenations.com)
Secondly if you do have a fever, insist on getting tested for malaria using a rapid diagnostic test (RDT) - remembering that not every fever is malaria. (naijanews.com)
Health workers are urged to maintain a high index of suspicion for Lassa fever when handling patients with fever, headache, sore throat and general body weakness, especially when malaria has been ruled out with a Rapid Diagnostic Test. (environewsnigeria.com)
Tests for the following were negative: Ebola, Hantavirus infection, Lassa fever, Marburg and malaria. (health.gov.au)
He is one of the leading lights in the field of science in Africa and has carried out research with focus on Human Genomics, Molecular Biology and Genomics of Infectious Disease like Lassa Fever, Malaria and Ebola. (infactng.com)
My research focus is on Human Genomics, Molecular Biology and Genomics of Infectious Diseases, especially Malaria, Viral Haemorrhagic Fevers (Lassa fever, Ebola Virus Disease, and others), and HIV. (infactng.com)
This is because many of the symptoms of MVD are similar to those found in other diseases such as malaria, typhoid fever, Lassa fever or Ebola. (bigpharmanews.com)

This disease was first reported in the city of Lassa, located in Borno State in the northwestern region of Nigeria. (highratedgabru.com)
The virus was first described in 1969 from a case in the town of Lassa, in Borno State, Nigeria. (wikipedia.org)
This virus has both a large and a small genome section, with four lineages identified to date: Josiah (Sierra Leone), GA391 (Nigeria), LP (Nigeria) and strain AV. Lassa virus commonly spreads to humans from other animals, specifically the Natal multimammate mouse or African rat, also called the Natal multimammate rat (Mastomys natalensis). (wikipedia.org)
Nigeria quickly made the diagnosis in the initial case of Ebola within its borders. (upr.org)
Nigeria is presently suffering from another Lassa fever epidemic . (bvsalud.org)
Since January 1, there have been 353 laboratory confirmed cases of Lassa fever and 78 deaths, according to the Nigeria Centre for Disease Control , compared with 143 confirmed cases in all of 2017 and 109 in 2016. (buzzfeednews.com)
The Ministry of Health in Nigeria has improved survey techniques, Rollin says, and there are now three laboratories in the country that can confirm the Lassa fever diagnosis, so this could also contribute to the increase in confirmed cases. (buzzfeednews.com)
Lassa fever is named after the town in Nigeria where the first cases occurred. (cdc.gov)
Nigeria has recorded reoccurring Lassa Fever outbreaks over the past 3 years. (helpinitiative.org)
In Nigeria, most cases of Lassa fever are reported during the dry season between November to March. (helpinitiative.org)
The disease was first identified in Nigeria in 1969 and is named after Lassa, a town in Borno state, where the first cases occurred when a prominent expert in the disease, Aniru Conteh, died from the disease. (helpinitiative.org)
This resource describes the standard operating procedures for Lassa fever case management as outlined by the Nigeria Centre for Disease Control. (lassafever.info)
Nucleotide research on the virus has revealed that Lassa virus contains four lineages recognized in Nigeria, Guinea, Liberia, and Sierra Leone. (bestnursingpapers.com)
They are the first link to response and care for Lassa fever cases in Nigeria. (gov.ng)
It is reported that Lassa fever, an animal-borne, or zoonotic, acute viral illness spread by the common African rat also known as the mastomys rat species is endemic to Nigeria and some other West African countries. (hsenations.com)
In Nigeria, Lassa fever usually occurs during dry season between January and April, claiming many lives, as other people get quarantined while undergoing treatment. (com.ng)
He said that with the tropical climate in Nigeria, there is risk of infectious diseases like Lassa fever because of the vector - rats and other rodents - which is also the case in other West African countries with similar environment. (com.ng)
He explained that "Nigeria is contributing to research for the development of Lassa Fever vaccine to proffer lasting solution to the disease. (com.ng)
According to him, Nigeria is contributing to research and other activities for the development of a Lassa fever vaccine. (com.ng)
However, some experts lament that with the predictable cycle of the destructive disease, Nigeria should have learnt and developed a more lasting solution and approach by now that can save people from the grip of the fever. (com.ng)
Lassa Fever is no news to us in Nigeria. (com.ng)
When we look at Lassa Fever from 2018-2020 according to Nigeria Centre for Disease Control (NCDC), can we say we are making progress? (com.ng)
Over the last five weeks, there has been a decline in the number of new cases of Lassa fever reported in Nigeria. (nigeriahealthwatch.com)
Importantly, Nigeria introduced her national Lassa fever research plan and has been recognised as one of the leading stakeholders in global Lassa fever research. (nigeriahealthwatch.com)
In the next one year, Nigeria is expected to be part of clinical trials towards the development of Lassa fever vaccines. (nigeriahealthwatch.com)
Over the past weeks, the Nigeria Centre for Disease Control (NCDC) reported a decrease in the number of new Lassa fever cases in Nigeria. (icanetwork.co.za)
The Nigeria Centre for Disease Control (NCDC) has made a new revelation about the spread of Lassa fever in Nigeria. (naijatweet.ng)
He said that there was need to carry out research more on the epidemiology of strains of the Lassa fever virus circulating in Nigeria to effectively track the source of future outbreaks. (politicsgovernance.com)
The Nigeria Centre for Disease Control and Prevention (NCDC), has registered 1,068 Lassa fever infections across 112 local government areas in 28 states of the federation. (fellowpress.com)
Please if your healthcare worker suspects Lassa fever, advise him or her to contact your local government disease surveillance and notification officer to access care in Nigeria. (gov.ng)

It's possible to prevent infection by avoiding areas where there are known outbreaks of Lassa fever. (highratedgabru.com)
If you have symptoms of Lassa fever and have recently been in an area where the virus is common, your doctor will likely order a blood test to confirm infection. (highratedgabru.com)
Dengue and dengue hemorrhagic fever (DHF) result from infection by any of four serotypes of dengue viruses. (cdc.gov)
In vitro studies reveal these cytokines lead to shock and increased vascular permeability, the basic pathophysiologic processes most often seen in viral hemorrhagic fever infection. (medscape.com)
Acute kidney injury with oliguria is a prominent feature of hemorrhagic fever with renal syndrome (HFRS) seen in Hantavirus infection and may be seen in other VHFs as intravascular volume depletion becomes more pronounced. (medscape.com)
Lack of timely laboratory diagnosis, late detection, inadequate infection control practices at health care facilities, and weak vector control programmes could also prolong outbreaks of haemorrhagic fevers. (who.int)
The symptoms of Lassa fever essentially arise within 1-3 weeks after infection. (firstaidcprvictoria.ca)
This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. (lassafever.info)
Lassa fever is a severe viral hemorrhagic infection caused by Lassa virus, which is affiliated to arenavidae virus family. (bestnursingpapers.com)
The national guidelines for Lassa fever case management and Infection prevention and control are available on the NCDC website for download ( http://ncdc.gov.ng/diseases/guidelines ). (gov.ng)
Lassa fever infection can be prevented by practising proper hand hygiene at all times - before and after using a toilet, before and after cooking, after being in crowded places, after dealing with animals and at other times. (hsenations.com)
He said the communication targeted all key stakeholders, from presidency to households, and would emphasise on the ways to prevent Lassa fever infection. (naijanews.com)
He urged healthcare workers to always apply standard infection prevention and control precautions when caring for patients, regardless of their presumed diagnosis as the healthcare setting could be particularly risky. (naijanews.com)
This highlights the need to implement standard infection prevention and control precautions with all patients regardless of their diagnosis. (environewsnigeria.com)
The diagnosis, suspected on clinical grounds, has been supported by laboratory tests, which confirm hantavirus infection. (health.gov.au)
no other clinical entity has attached more attention now-a-day than those precipitated by the infection with a hemorrhagic fever virus. (liverpool.ac.uk)
Ensuring staff in Lassa fever treatment centres apply extra infection control measures to prevent contact with the patient's blood and body fluids and contaminated surfaces or materials. (com.ng)
This includes the early deployment of One-Health national RRTs, improvement of functions in Lassa fever treatment centres, revision of case management guidelines, enforcement of environmental sanitation in some states, introduction of the Infection Prevention and Control (IPC) ring strategy, targeted intensified risk communications activities, high level advocacy visits, operational research into response activities, amongst others. (nigeriahealthwatch.com)
Our research work has also resulted in identification of new genes associated with human resistance to infection of Lassa fever virus. (infactng.com)
"The outcome of the risk assessment placed the country at a very high risk of increased Lassa fever transmission due to an unprecedented upward trend in the number of confirmed cases being reported compared to previous years, increased number of states reporting cases in comparison to previous years and increased risk of healthcare worker infections and deaths due to Lassa fever infection," the statement reads. (naijatweet.ng)
Ahead of the projected rise of Lassa fever cases and as the country began to witness a rise in cases in the last week on November 2022, the NCDC prepositioned supplies for case management, infection prevention and control, laboratory diagnosis, etc. in all historical Lassa fever hotspots in the country. (naijatweet.ng)

Symptoms of Lassa fever and South American arenavirus hemorrhagic fevers usually start about 5 to 16 days after people are exposed to the virus. (merckmanuals.com)
Lassa fever, which is caused by an arenavirus, can affect multiple organs and cause bleeding in late stages. (upr.org)
Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to be responsible for a severe haemorrhagic fever characterised by fever, muscle aches, sore throat, nausea, vomiting and, chest and abdominal pain. (folkhalsomyndigheten.se)
Lassa virus, the causality of the Lassa fever belongs to genus arenavirus and arenavidae family (Clercq & Kern, 2003). (bestnursingpapers.com)
VHF refers to viral hemorrhagic fever caused by either Ebola, Lassa, Lujo, or Marburg virus, a New World arenavirus, or Crimean-Congo hemorrhagic fever. (cdc.gov)
Important agents are Lassa fever virus ( Arenavirus ), Ebola virus, Marburg virus ( Filoviradae ) and Crimean-Congo haemorrhagic fever virus. (nsw.gov.au)

The world body also urged health workers to adhere to standard precautions by wearing protective equipment like gloves, face masks, face shields and aprons when handling suspected Lassa fever patients. (environewsnigeria.com)

The precise species of the rodent associated with disease has not yet been discovered, but it is largely believed that species natalensis is responsible for fever. (bestnursingpapers.com)
The Lassa virus is transmitted to humans via contact with food or household items contaminated with infected rodent urine or faeces. (naijanews.com)
The animal host of Lassa virus is a rodent known as the "multimammate rat" of the genus Mastomys. (outbreaknewstoday.com)
Humans get infected with Lassa through aerosol or direct contact with excreta from the rodent. (outbreaknewstoday.com)
The preliminary results of 42 Lassa fever virus sequences indicate that rodent to human transmission, as observed in 2018, is still the dominant route of transmission. (nigeriahealthwatch.com)
Iwalokun said that Lassa fever could be transmitted to humans through food stuffs and household items contaminated with rodent urine and faeces. (politicsgovernance.com)

The A aegypti mosquito is a known transmitter of both dengue fever and yellow fever. (medscape.com)
In the Eastern Mediterranean Region, the main viral haemorrhagic fevers are yellow fever, Rift Valley fever, dengue fever, Crimean-Congo haemorrhagic fever and Ebola virus disease. (who.int)
mosquito bites (Rift Valley fever, Dengue) or ticks (Crimean-Congo haemorrhagic fever). (who.int)
In the past 2 decades, the Eastern Mediterranean Region has witnessed major outbreaks as well as sporadic cases of yellow fever, Rift valley fever, severe dengue and Crimean-Congo haemorrhagic fever in over 12 countries. (who.int)
Central disorders produce gaze pareses and nystagmus in the differential diagnosis of dengue fever, lassa fever virus is easily treatable. (surgicalimpex.com)

300,000 Lassa virus (LASV) infections occurring annually ( 1 ). (cdc.gov)
Hemorrhagic Fevers Overview Hemorrhagic fevers are serious viral infections characterized by bleeding (hemorrhage). (merckmanuals.com)
About 1% of all Lassa virus infections result in death. (wikipedia.org)
Lassa fever patients are advised to stay rehydrated, maintain normal blood pressure as well as treatment of any other complicating infections. (helpinitiative.org)
The mild infections include generalized malaise, light fever and headache . (firstaidcprvictoria.ca)
Avoiding nosocomial transmission of infections in health-care settings, with health care workers observing all necessary IPC precautions when caring for patients, regardless of their presumed diagnosis. (com.ng)
Despite the occasional disaster drill, very few of our medical staff have ever had to protect themselves from (life-threatening) hemorrhagic fever infections in their patients. (blogspot.com)

Typhoid fever and so on. (bvsalud.org)

About half of those who die of Lassa fever die within five days of developing symptoms. (highratedgabru.com)
If a person has been in an area where Lassa fever is common and has symptoms of the disease, a blood test can be done to look for the virus. (highratedgabru.com)
There is no specific cure for Lassa fever and treatment focuses on relieving symptoms and supporting the patient through the illness. (highratedgabru.com)
Diagnosis based on symptoms is difficult. (wikipedia.org)
Hence no laboratory evidence exists for any of them having had Ebola and so these diagnoses rest on symptoms alone. (vectorsjournal.org)
People who contract Lassa fever usually have mild or no symptoms, but in severe cases it can cause bleeding, deafness, or organ failure. (buzzfeednews.com)
However, these symptoms are typically mild, so a person may recover and never know that they had Lassa fever, which has to be confirmed with laboratory testing. (buzzfeednews.com)
One approach focuses on symptoms, Rollin says, which means getting the fever down and giving the person fluids and supportive care. (buzzfeednews.com)
An estimated 80% of people who become infected with Lassa virus have no symptoms, which increases the risk of transmitting the disease. (helpinitiative.org)
The signs and symptoms of Lassa fever typically occur 1-3 weeks after the patient comes in contact with the virus. (helpinitiative.org)
The symptoms of Lassa fever vary widely, and diagnosis can be difficult. (helpinitiative.org)
Lassa fever is a viral ailment carried by the multimammate rat (Mastomys natalensis) with various symptoms that can be deadly. (firstaidcprvictoria.ca)
Maintain a high index of suspicion for Lassa fever i.e. be vigilant and look out for Lassa fever symptoms. (gov.ng)
All the 396 contacts have not shown any abnormal symptoms or signs of Lassa fever, their temperature is under control and we have stationed our monitoring officer with each of the contacts to continue monitoring throughout a specific period in line with the World Health Organisation standard," health commissioner Babatunde Ipaye said. (naijanews.com)
However, because the symptoms of Lassa fever are so varied and non-specific, clinical diagnosis is often difficult, especially early in the course of the disease. (outbreaknewstoday.com)
While Lassa fever is mild or has no observable symptoms in about 80% of people infected with the virus, the remaining 20% have a severe multisystem disease. (outbreaknewstoday.com)
The symptoms of Lassa fever typically occur 1-3 weeks after the patient comes into contact with the virus. (outbreaknewstoday.com)
Clinical diagnosis of MVD is difficult in the early phase as symptoms are similar to other febrile illnesses. (unamhe.or.ug)

Hepatic involvement varies with the infecting organism and is at times seen with Ebola, Marburg, RVF, Crimean-Congo hemorrhagic fever (CCHF), and yellow fever. (medscape.com)
in 1987, an isolated case of fatal marburg disease was recognized during routine clinical haemorrhagic fever virus surveillance conducted in kenya. (liverpool.ac.uk)
Illness caused by Marburg virus begins abruptly, with high fever, severe headache, and severe malaise. (unamhe.or.ug)
History of travel to an endemic/epidemic area within 9 days (Marburg), 13 days (Crimean Congo) or 21 days (Lassa, Ebola) of illness onset. (nsw.gov.au)

Since the Lassa fever outbreaks typically last until April or May, Rollin says, there is still some time to go before the Ministry of Health has final numbers. (buzzfeednews.com)
Furthermore, Lassa virus has cluding Liberia, Sierra Leone, Guinea, Mali and been associated with nosocomial outbreaks with high Senegal5-7. (folkhalsomyndigheten.se)

According to Mr. Ihekweazu, the committee came up with an approach that focused on strengthening the capacities and capabilities of states to prevent, detect and respond to Lassa while the NCDC coordinates the efforts. (naijanews.com)
The NCDC boss noted that the five laboratories have the capacity to diagnose Lassa fever in the country. (com.ng)
In these states, NCDC has also supported full availability of drugs, personal protective equipment, laboratory reagents and other supplies required for case management and diagnosis of Lassa fever. (nigeriahealthwatch.com)
In January 2019, NCDC hosted the first Lassa fever International Conference. (nigeriahealthwatch.com)
The NCDC says the country is at a very high risk of increased Lassa fever transmission. (naijatweet.ng)
The NCDC said this via its official website on Tuesday in its Lassa Fever Situation Report for Week 37 (Sep. (fellowpress.com)
The NCDC said that early diagnosis and prompt medical care are crucial in managing the disease and preventing complications. (fellowpress.com)

Patients were suspected of having Lassa fever on clinical grounds by physicians of the United Nations peacekeeping troops and other international relief organizations. (cdc.gov)
She had the clinical acumen to suspect the diagnosis and ensure that her patient was tested. (upr.org)
Like other arenaviruses, Lassa virus lacks a ogy and clinical presentation, treatment, prevention conventional negative-strand coding arrangement and control as well as the current theories of its patho- and the isolates of the virus differ in their genetic, genesis and efforts in vaccine development. (folkhalsomyndigheten.se)
Additionally, much greater priority needs to be given to ensuring clinicians have the basic tools for clinical diagnosis, as well as greater investments in essential laboratory and radiographic diagnostics that help LMIC clinicians move beyond the sole reliance on algorithm based clinical decision making. (bvsalud.org)
This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. (lassafever.info)
This paper discusses Lassa fever, an infectious disease with regard to its causality organism, transmission, epidemiology, and factors causing the illness, clinical manifestation and diagnosis and the role of the nurse in controlling the illness. (bestnursingpapers.com)
Surveillance case definitions are not intended to be used by healthcare providers for making a clinical diagnosis or determining how to meet an individual patient's health needs. (cdc.gov)
My current research activities consist of using innovative approaches that combines patient care, fieldwork, laboratory, molecular biology and genomics methods for discoveries that have shifted the paradigm in clinical research and applications in parasites and viral diagnosis, parasites biology and genomics, Pharmacogenomics, and human genomics. (infactng.com)
Clinical diagnosis of MVD can be difficult, especially if only one case is involved. (bigpharmanews.com)
Crimean-Congo hemorrhagic fever virus) 5 to capture the majority of phylogenetic lineages and mitigate diagnostic errors on clinical interpretation. (nature.com)

If you are diagnosed with Lassa fever it is important to seek medical care because there are treatments available which can help prevent severe illness or death. (highratedgabru.com)
Lassa fever is an animal-borne, or zoonotic, acute viral illness spread by the common African rat. (cdc.gov)
When the RDT is negative, other causes of febrile illness including Lassa fever should be considered and cases investigated accordingly. (gov.ng)
It is an animal-borne or zoonotic illness caused by the Lassa virus, hence, it was named after the town where the first cases originated. (com.ng)
After an incubation period of 1-3 days after a tick bite or 5-6 days after exposure to infected blood, CCHF produces an initial illness with sudden onset of fever, weakness, malaise, and back pain lasting 2-7 days. (logicalimages.com)

Lassa fever can be difficult to distinguish clinically from other viral hemorrhagic fevers, such as Ebola virus disease. (wikipedia.org)
Viral hemorrhagic fevers (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. (medscape.com)

Lassa fever is not new and was first identified in 1969. (buzzfeednews.com)

In 2020, 195 cases of Lassa fever have been reported with about 29 recorded deaths. (helpinitiative.org)

Reliable laboratory diagnosis, particularly in acute cases, is crucial for triage, implementation of barrier nursing, and contact tracing, as well as for initiation of treatment with ribavirin. (cdc.gov)
Once a laboratory test confirms someone has Lassa fever, there are typically two types of treatment. (buzzfeednews.com)
Point-of-care and point-of-'can': Leveraging reference-laboratory capacity for integrated diagnosis of fever syndromes in the tropics. (cdc.gov)
The only definitive tests for Lassa fever are laboratory-based, and the handling of specimens can be hazardous. (helpinitiative.org)
The preparedness can be improved through continuous community-based surveillance of Lassa fever by public awareness and adequate laboratory to generate data for trend analysis. (politicsgovernance.com)
Most people will be critically ill (or dead) by the time a confirmed laboratory diagnosis can be made. (blogspot.com)

It is an acute viral haemorrhagic fever (VHF) caused by the Lassa virus. (gov.ng)

According to a statement issued by WHO's Communication Officer, Ms Charity Warigon in Abuja on Friday, May 11, 2018, continued vigilance is, however, needed as the country is still Lassa fever endemic. (environewsnigeria.com)

We recently discovered new viruses (EKV-1 and EKV-2, and developed new rapid diagnoses for Ebola virus disease (EVD), and Lassa fever virus. (infactng.com)

Hemorrhagic fevers can be caused by many different types of virus. (merckmanuals.com)
The diagnosis of Lassa fever or a South American hemorrhagic fever is confirmed by blood tests to identify the virus or antibodies to the virus. (merckmanuals.com)
Lassa fever is a viral hemorrhagic fever caused by the Lassa virus. (highratedgabru.com)
Who gets infected with the Lassa virus? (highratedgabru.com)
Lassa virus is transmitted to humans through contact with infected rodents, typically the multimammate mouse. (highratedgabru.com)
The Lassa virus is a member of the Arenaviridae family of viruses. (wikipedia.org)
The Lassa virus, which is carried and transmitted by rodents for the most part, poses different challenges. (upr.org)
Poor antibody response to yellow fever vaccination in children infected with human immunodeficiency virus type 1. (medscape.com)
Goujon C, Tohr M, Feuille V. Good tolerance and efficacy of yellow fever vaccine among subjects who are carriers of human immunodeficiency virus. (medscape.com)
Lassa fever is normally spread to humans from rodents carrying the Lassa virus. (buzzfeednews.com)
Lassa fever is caused by a virus that normally infects rodents. (buzzfeednews.com)
Epidemics of Lassa fever were have comprehensive information about the virus and also documented in other West African countries in- the disease it causes. (folkhalsomyndigheten.se)
A few cases of the importation of Lassa mortality10,11, hence, early identification of infected virus into other parts of the world for example by individuals is important for prompt implementation travellers were documented17-20. (folkhalsomyndigheten.se)
Alkhurma Hemorrhagic Fever Virus RNA in Hyalomma rufipes Ticks Infesting Migratory Birds, Europe and Asia Minor. (cdc.gov)
A high number of patients met the case definition for Lassa fever yet ultimately tested negative for the virus and no causative pathogen was identified. (cdc.gov)
The Lassa virus, shown here, causes Lassa fever. (cdc.gov)
Ribavirin an antiviral drug has proven useful in fighting the Lassa virus if prescribed early. (helpinitiative.org)
Ergonul & Whitehouse (2007) affirms that Lassa virus has receptors on its cell surface called the alpha-dystroglycan (alpha-DG) used for gaining access into the host cell. (bestnursingpapers.com)
Lassa virus' receptors are distinguished by a particular sugar alteration on alpha-DG referred to as glycosyltransferases (Frey & Price, 2003). (bestnursingpapers.com)
Lassa virus uses an endocrytic pathway that lacks clathrin, caveolin, dynamin, and actin unlike other enveloped viruses. (bestnursingpapers.com)
The multimammate rat scientifically referred to as mastomys natalensis is the natural reservoir of Lassa virus, which causes Lassa fever. (bestnursingpapers.com)
Rodents are present inside houses where people live and some of these rodents are the reservoir of the Lassa virus (Georgiev, 2009). (bestnursingpapers.com)
the media have brought to the public's attention many newly described infectious diseases, such as ebola virus hemorrhagic fever, that were not part of common medical parlance a decade ago. (liverpool.ac.uk)
The U.S. Food and Drug Administration (FDA) announced the addition of Lassa fever, chikungunya virus disease, rabies and cryptococcal meningitis to its list of tropical diseases. (precisionvaccinations.com)
Crimean-Congo hemorrhagic fever (CCHF) produces a viral hemorrhagic fever syndrome caused by a virus of the Bunyaviridae family. (logicalimages.com)

Our study underscores the utility and shortcomings of RT-PCR diagnostics for Lassa fever. (cdc.gov)

There were 1081 suspected cases and 90 reported deaths, however, only 317 cases and 72 deaths were confirmed as Lassa fever. (helpinitiative.org)

Transmission occurs through the bite of infected Aedes mosquitoes, principally Aedes aegypti, which is also the principal urban vector of yellow fever. (cdc.gov)
Yellow fever: a reemerging threat. (medscape.com)
The enigma of yellow fever in East Africa. (medscape.com)
Imported yellow fever in a United States citizen. (medscape.com)
Fatal yellow fever in a traveler returning from Venezuela, 1999. (medscape.com)
Fatal yellow fever in a traveler returning from Amazonas, Brazil, 2002. (medscape.com)
Barnett ED. Yellow fever: epidemiology and prevention. (medscape.com)
Yellow fever vaccines and international travelers. (medscape.com)
Patel D, Simons H. Yellow fever vaccination: is one dose always enough? (medscape.com)
Staples JE, Bocchini JA Jr, Rubin L, Fischer M. Yellow Fever Vaccine Booster Doses: Recommendations of the Advisory Committee on Immunization Practices, 2015. (medscape.com)
Staples JE, Gershman M, Fischer M. Yellow fever vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). (medscape.com)
Yellow fever vaccine: an updated assessment of advanced age as a risk factor for serious adverse events. (medscape.com)
Yellow fever vaccination and pregnancy: a four-year prospective study. (medscape.com)
Yellow fever vaccination during pregnancy and spontaneous abortion: a case-control study. (medscape.com)
A aegypti is sometimes referred to as the yellow fever mosquito. (medscape.com)
Viral haemorrhagic fevers are associated with occurrence of major epidemics with high case-fatality rates owing to the fact that there are no specific medical countermeasures such as vaccines or antivirals, the exception being yellow fever. (who.int)
The diagnosis of yellow fever by culture and PCR was confirmed today. (health.gov.au)

A vaccine for Lassa fever does not exist yet but researchers are working on developing one. (highratedgabru.com)
There is no vaccine for Lassa fever, and early treatment is critical. (buzzfeednews.com)

The main focus of the prevention of Lassa fever is maintaining community hygiene to control the rat population. (helpinitiative.org)
It added that prevention of Lassa fever involves avoiding contact with rodents and their droppings, practising good personal hygiene and taking precautions when caring for infected individuals. (fellowpress.com)

The use of buildings for housing and commercial activities was found to be a risk for the transmission of Lassa fever in the houses. (lassafever.info)
This is an advisory to health care workers, to prevent person to person transmission of Lassa fever especially in health care settings. (gov.ng)
Inappropriate use of personal protective equipment (PPE) such as gloves, masks and poor IPC practices, increase the risk of person to person transmission of Lassa fever. (gov.ng)

2019 . Lassa fever diagnostics: past, present, and future . (ajtmh.org)

On 5 August, the Robert Koch Institute in Berlin provided WHO with more details on the previously reported case of a man hospitalised with suspected haemorrhagic fever, after returning from a trip to C te d'Ivoire. (health.gov.au)
A case of haemorrhagic fever with renal syndrome (HFRS) has been confirmed in Kosovo. (health.gov.au)
ebola haemorrhagic fever. (liverpool.ac.uk)
Hospitalise at the Viral Haemorrhagic Fever Treatment Facility, Westmead Hospital. (nsw.gov.au)

Medical or hospital support staff preparing and/or handling dead bodies of Lassa fever patients without appropriate precautions. (gov.ng)

We summarize our experiences from testing 184 patients from Liberia with suspected cases of Lassa fever with the most widely used LASV-specific RT-PCR assay ( 6 ). (cdc.gov)
About 80% of cases of Lassa fever are mild and are often not diagnosed. (merckmanuals.com)
There have been more confirmed cases of Lassa fever in the first two months of 2018 than there have been in the last two years combined. (buzzfeednews.com)
Epidemiological data show that Lassa fever occurs throughout the year, but more cases are recorded during the dry season i.e. (gov.ng)
Please report all suspected cases of Lassa fever to your Local Government Area Disease Surveillance and Notification Officer (DSNO). (gov.ng)
Warigon said that in the week ending May 6, only three new confirmed cases of Lassa fever were reported, stating that people could still be infected throughout the year hence the need for continued vigilance. (environewsnigeria.com)
Strengthening of Lassa fever awareness campaign and education across the country, mostly at the primary healthcare level, so as to increase the level suspicion of index cases in rural areas. (politicsgovernance.com)
Seventy-five per cent of all confirmed Lassa fever cases were reported from these three states (Ondo, Edo, and Bauchi) while 25 per cent were reported from 25 states with confirmed Lassa fever cases. (fellowpress.com)

Practice standard precautions at all times while handling patients and body fluids i.e. always perform hand hygiene at the designated five moments, wear the correct PPE based on the procedure to be performed, irrespective of provisional diagnosis of the patient. (gov.ng)

Persons on humanitarian missions and peacekeeping forces in regions comprising Sierra Leone and Liberia are at risk for Lassa fever ( 2 - 4 ). (cdc.gov)
In some areas of Sierra Leone and Liberia, about 10-16% of people admitted to hospitals annually have Lassa fever. (cdc.gov)
This is an update on Lassa fever in Sierra Leone from the 14th June 1996. (lassafever.info)
Chapter 5 of Annie Wilkinson's PhD thesis, provides a detailed description of health seeking behaviours for Lassa Fever in rural Sierra Leone. (lassafever.info)

To confirm the diagnosis, doctors do blood and urine tests. (merckmanuals.com)
A combination of pharyngitis, pain behind the sternum, presence of excess protein in the urine and fever can indicate Lassa fever with higher specificity. (wikipedia.org)

Viral haemorrhagic fevers include a spectrum of relatively mild to severe life-threatening diseases characterized by sudden onset of muscle and joint pain, fever, bleeding and shock from loss of blood. (who.int)

Ihekweazu added that the laboratories would also play key roles in the Lassa fever epidemiological study that would provide data to guide research and response activities. (com.ng)

Organisms10

Diseases14

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Anthropology, Education, Sociology and Social Phenomena1

Named Groups1

Health Care3

Geographicals5

Outbreak26

West Africa17

Malaria13

Nigeria30

Infection21

Arenavirus6

Suspected Lassa fever patients1

Rodent6

Dengue5

Infections7

Typhoid fever1

Symptoms18

Marburg4

Outbreaks2

NCDC7

Clinical10

Illness5

Viral Hemorrhagic Fevers2

19691

20201

Laboratory6

Acute viral1

Endemic1

Ebola Virus D1

Virus25

Diagnostics for Lassa fever1

Deaths1

Yellow fever17

Vaccine for Lassa fever2

Prevention of Lassa fever2

Transmission of Lassa fever3

20191

Haemorrhagic fever4

Appropriate precautions1

Cases8

Precautions1

Sierra Leone4

Urine2

Mild1

Epidemiological1