Myelodysplastic SyndromesMyeloproliferative DisordersBone MarrowJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialBone Marrow CellsAnemia, RefractoryBone Marrow NeoplasmsLeukemia, Myelomonocytic, ChronicBone Marrow TransplantationReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteBone and BonesThrombocytosisSyndromeBone Marrow DiseasesLeukemia, MyeloidHematopoietic Stem CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeAnemia, SideroblasticMutationLeukemia, Myelomonocytic, JuvenileBone Marrow ExaminationChromosomes, Human, Pair 5LeukemiaHematologic NeoplasmsSplenomegalyLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProto-Oncogene Proteins c-cblPrognosisKaryotypingHematopoiesisBlast CrisisAzacitidineAnemia, AplasticChromosome AberrationsPhiladelphia ChromosomeBone RemodelingTreatment OutcomeMegakaryocytesPreleukemiaHematologyMyeloid Progenitor CellsPancytopeniaTransplantation, HomologousMonosomyDNA Mutational AnalysisAcute DiseaseHematopoietic Stem Cell TransplantationJanus KinasesThalidomideAntigens, CD34Disease ProgressionMegakaryocyte Progenitor CellsChromosomes, Human, Pair 7Colony-Forming Units AssaySTAT5 Transcription FactorMice, Inbred C57BLCell Transformation, NeoplasticBone DensityMegakaryocyte-Erythroid Progenitor CellsGranulocytesCytogenetic AnalysisMyelopoiesisFlow CytometryNeoplasms, Second PrimaryMutation, MissenseClonal EvolutionCell ProliferationCell DifferentiationChromosome DeletionBlood Cell CountFusion Proteins, bcr-ablAntineoplastic AgentsRetrospective StudiesGranulocyte Precursor CellsBone ResorptionPolymerase Chain ReactionWhole-Body IrradiationBone NeoplasmsCytogeneticsErythropoietinSurvival AnalysisNeoplasmsHematologic DiseasesPhenotypeImmunophenotypingGranulocyte Colony-Stimulating FactorPoint MutationGene Knock-In TechniquesAmino Acid SubstitutionTransplantation, AutologousTranslocation, GeneticBone Marrow PurgingProtein Kinase InhibitorsProto-Oncogene Proteins