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BacteremiaGram-Negative Bacterial InfectionsSepsisAnti-Bacterial AgentsStaphylococcal InfectionsGram-Positive Bacterial InfectionsRetrospective StudiesBloodCross InfectionDelayed DiagnosisEarly DiagnosisSensitivity and SpecificityPrenatal DiagnosisStaphylococcus aureusCatheters, IndwellingCatheterization, Central VenousVancomycinStreptococcal InfectionsEndocarditis, BacterialProspective StudiesTreatment OutcomeMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsRisk FactorsEscherichia coli InfectionsCatheter-Related InfectionsGram-Negative BacteriaDiagnosisInfant, NewbornCommunity-Acquired InfectionsBacteriological TechniquesPneumococcal InfectionsActinomycetales InfectionsKlebsiella InfectionsIncidenceMethicillin ResistanceEnterobacteriaceae InfectionsTime FactorsCohort StudiesPseudomonas InfectionsFeverVancomycin ResistanceEnterococcusCellulitisDrug Resistance, BacterialDiagnostic ErrorsFatal OutcomePredictive Value of TestsPolymerase Chain ReactionPrognosisSalmonella InfectionsGram-Positive BacteriaImmunocompromised HostBartonella InfectionsBartonella quintanaBacterial InfectionsDNA, BacterialAcinetobacter InfectionsStreptococcus pneumoniaeViridans StreptococciEndocarditisHospitals, UniversityTomography, X-Ray ComputedBacterial Typing TechniquesKlebsiella pneumoniaeDaptomycinTrench FeverEquipment ContaminationAbscessBiopsyAntibiotic ProphylaxisPneumonia, BacterialStaphylococcusRNA, Ribosomal, 16SNeutropeniaAntibodies, BacterialBacteriaFollow-Up StudiesUrinary Tract InfectionsNursing DiagnosisReproducibility of ResultsStreptococcusDiagnosis, Computer-AssistedMeningitisCoagulaseCase-Control StudiesHaemophilus InfectionsFever of Unknown OriginFungemiaIntensive Care UnitsPrevalencePseudomonas aeruginosaOsteomyelitisRecurrenceLeptotrichiaPneumonia, PneumococcalShock, SepticTooth ExtractionPregnancyAge Factors

MeningitisSeptic shockPneumoniaBacteriaOsteomyelitisEndocarditisSepsisBloodstreamInfectionsFeverSevereInfectionAureusStaphylococcalOccultRetrospective studyDiseaseBiomarkersProgressionFetusAntibioticAntibioticsDetectionAbscessLemierre'sTreatmentAcuteGonococcal ArthritisPatientsImmuneInfectiousBloodMortalityAdultsManagementPatientPediatricIntenseEarlyInitial diagnosisSpinal

Meningitis4

• These include urinary tract infections, bacteremia (bacteria in the blood) and bacterial meningitis (bacterial infection of the membrane housing the brain and spinal cord). (nih.gov)
• The most severe complications of cellulitis are meningitis and blood poisoning (if the bacteria get into the bloodstream, called bacteremia ). (medbroadcast.com)
• Infection can be invasive and result in pneumococcal pneumonia, pneumococcal bacteremia (bacterial infection of the blood), or pneumococcal meningitis. (who.int)
• Haemophilus influenzae non-type b strains can cause invasive disease clinically similar to type b (Hib) disease (pneumonia, bacteremia, meningitis, epiglottitis, septic arthritis, cellulitis, or purulent pericarditis). (cdc.gov)

Septic shock2

• Bacteremia may lead to septic shock, whose symptoms include decreased consciousness, rapid heart and breathing rates and multiple organ failures. (faqs.org)
• However, her clinical course was complicated and included disseminated CMV disease and subsequent septic shock due to bacteremia. (nih.gov)

Pneumonia1

• a diagnosis of pneumonia. (cdc.gov)

Bacteria6

• Viral replication leads to the host entering an immune-compromised state, evolving towards subsequent bacteraemia by opportunistic bacteria. (nature.com)
• Bacteremia, in which bacteria spread into your blood. (webmd.com)
• Bacteremia occurs when bacteria enter the bloodstream. (faqs.org)
• The bacteria most likely to cause bacteremia include members of the Staphylococcus, Streptococcus, Pseudomonas, Haemophilus, and Esherichia coli ( E. coli ) genera. (faqs.org)
• Bacteremia is diagnosed by culturing the blood for bacteria. (faqs.org)
• Occult bacteremia is the presence of bacteria in the bloodstream of febrile young children who have no apparent foci of infection and look well. (msdmanuals.com)

Osteomyelitis6

• [1] Vertebral osteomyelitis often has a nonspecific clinical presentation and thus delayed diagnosis up to several months is not uncommon. (nih.gov)
• The aim of this article is to elucidate key points in the presentation, workup, and treatment of vertebral osteomyelitis to support rapid clinical diagnosis and management. (nih.gov)
• [2] Thus a diagnosis of vertebral osteomyelitis should be assumed (without the need for a disc space aspiration or another tissue sampling) in a patient with S. aureus bacteremia within the preceding 3 months and compatible spine magnetic resonance imaging (MRI) findings. (nih.gov)
• Any condition that causes a bacteremia (even temporary bacteremia such as tooth brushing or venipuncture) may lead to hematogenous vertebral osteomyelitis. (wheelessonline.com)
• Any condition that causes a bacteremia may lead to hematogenous vertebral osteomyelitis. (wheelessonline.com)
• 34 Many now believe that the sluggish flow, scarcity of valves and convolution of the arterial or venous supply leads to vertebral osteomyelitis in patients with bacteremia. (wheelessonline.com)

Endocarditis1

• This clinic sees a wide variety of patients with diagnoses that include post-operative wound infections, endocarditis (inflammation around the heart), bacteremia (blood poisoning), as well as tropical diseases , sexually transmitted diseases, and tuberculosis. (ottawahospital.on.ca)

Sepsis3

• The management and diagnosis of early onset sepsis (EOS) in term and preterm infants continues to evolve with wide variation in practice globally. (bmj.com)
• 7 This means, that if the clinical diagnosis of chorioamnionitis is considered an absolute indication for empirical antibiotic administration, many healthy infants are ultimately treated with empirical antibiotics to treat suspected sepsis and prevent progression to severe clinical illness. (bmj.com)
• She was admitted from the ER with severe sepsis…and bacteremia. (beckershospitalreview.com)

Bloodstream3

• Septicemia is an infection in the bloodstream (also called bacteremia) that may travel to different body organs. (medlineplus.gov)
• Two recent studies published in Infection Control and Hospital Epidemiology draw attention to two simple clinical practices that can have a great impact on diagnosis and management of C difficile (laxative use) [ 1 ] and bloodstream infections (blood sample volume for blood cultures). (medscape.com)
• Obtaining an adequate sample volume for blood cultures is important in the detection of bacteremia because underfilling blood culture bottles is associated with increased levels of blood contamination, increased time to positivity, and reduced sensitivity for detecting bloodstream infections. (medscape.com)

Infections7

• Bacteremia can be prevented by preventing the infections which often precedeit. (faqs.org)
• The usefulness of blood culture time-to-positivity (TTP) in the diagnosis of endovascular infections has previously been shown. (lu.se)
• These infections are difficult to treat and delays in diagnosis further complicate patients' clinical management. (cdc.gov)
• Such infections could be minimized by early identification and treatment of the bacteremia. (msdmanuals.com)
• However, diagnosing bacteremia is challenging for clinicians, especially in children presenting with co-infections such as malaria and HIV. (listlabs.com)
• The most common sources are urinary tract infections and the transient bacteremia caused by genitourinary procedures. (wheelessonline.com)
• An evolving understanding of urinary tract infections has led one expert to describe them as an "ambiguous, expansive, overused diagnosis" that can lead to the myriad harms of antibiotic overtreatment. (acpinternist.org)

Fever5

• To use an index score to identify an adult with acute, unexplained fever who has bacteremia or an occult bacterial infection. (medicalalgorithms.com)
• Bacteremia may cause no symptoms and resolve without treatment, or it may produce fever and other symptoms of infection. (faqs.org)
• In the era before conjugate vaccines, about 3 to 5% of children aged 3 to 36 months with a febrile illness (temperature ≥ 39 ° C) and no localizing abnormalities (ie, fever without a source) had occult bacteremia. (msdmanuals.com)
• By the end of the investigation, serologic diagnosis of Q fever appeared to be positive for both IgG and IgM. (hindawi.com)
• Diagnosis of Q fever is based on the serologic test. (hindawi.com)

Severe2

• In another, a patient developed a severe infection during her pregnancy in a state with an abortion ban, but was sent home after an initial diagnosis of a preterm premature rupture of the membranes. (beckershospitalreview.com)
• P. aeruginosa bacteremia is a common and severe infection carrying high mortality in older adults . (bvsalud.org)

Infection7

• Since bacteremia is usually associated with an existing infection elsewhere in the body, finding and treating this infection isan important part of treatment. (faqs.org)
• Therefore, it is imperative that patients and providers are informed about the risk of infection associated with use of the 3T device and the need for appropriate diagnostic evaluation to facilitate timely diagnosis and treatment. (cdc.gov)
• Diagnosis is by blood culture and exclusion of focal infection. (msdmanuals.com)
• 36 months with bacteremia almost always looked ill and had an identifiable (ie, non-occult) focus of infection. (msdmanuals.com)
• The diagnosis of intra-amniotic infection is challenging and can only be definitively established by amniotic fluid culture, Gram stain or biochemical analysis. (bmj.com)
• Diagnosis is difficult as signs and symptoms of infection are not specific. (pediatriconcall.com)
• 5,14 That prevalence of this infection increases with age is possibly due to a number of factors: the increasing age of the population, increasing number of patients on renal replacement therapy, increasing number of patients with immunosuppressive medications and increasing rates of bacteremia due to intravascular devices and other forms of instrumentation. (wheelessonline.com)

Aureus1

• Usually results from bacteremia with virulent pathogens such as Staphylococcus aureus , Salmonella , or possibly Candida . (logicalimages.com)

Staphylococcal1

• In this manuscript, we also demonstrate the application of these methods for the detection of LPS in serum from pediatric patients with invasive Salmonella Typhimurium bacteremia (n=7) and those with Staphylococcal bacteremia (n=7) with 100% correlation with confirmatory culture. (listlabs.com)

Occult1

• The causes, evaluation, and management of possible occult bacteremia vary by children's age and immunization status. (msdmanuals.com)

Retrospective study2

• Comparison of clinical diagnoses and autopsy findings: six-year retrospective study. (ahrq.gov)
• Outcomes of octogenarians and nonagenarians with Pseudomonas aeruginosa bacteremia: a multicenter retrospective study. (bvsalud.org)

Disease8

• Sequencing of a skin biopsy specimen confirmed the diagnosis of Chagas disease. (nih.gov)
• thus education about all symptoms related to this disease is essential to ensure its early diagnosis. (jointhealthmagazine.com)
• The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease burden areas. (listlabs.com)
• Familiar with the clinical features of BS and the diagnosis and treatment plan can play a positive role in the prevention and treatment of the disease. (scirp.org)
• The epidemiology, mechanisms, diagnosis and treatment of cardiovascular disease in adult patients with HIV. (moffitt.org)
• This information day served as a reminder of advances in knowledge of this disease and the need to raise awareness of prevention, diagnosis and treatment. (pasteur.fr)
• In older adults with P. aeruginosa bacteremia , background conditions, place of acquisition, and disease severity are associated with mortality , rather than the antimicrobial regimen. (bvsalud.org)
• Positive antigen test results from urine or serum samples are unreliable for diagnosis of Haemophilus influenzae disease and should not be used as a basis for case classification. (cdc.gov)

Biomarkers1

• In this manuscript, we have developed and clinically validated a novel method for the direct detection of amphiphilic pathogen biomarkers indicative of bacteremia, directly in aqueous blood, by mimicking innate immune recognition. (listlabs.com)

Progression1

• The likelihood of progression to serious focal illness depended on the cause: 7 to 25% for bacteremia caused by H. influenzae type b but 4 to 6% for bacteremia caused by S. pneumoniae . (msdmanuals.com)

Fetus1

• We present a case of C. fetus subsp fetus bacteremia in a premature newborn of a substance-abusing mother with chorioamnionitis. (pediatriconcall.com)

Antibiotic2

• Regarding the clinical management of enterococcal bacteraemia, the evidence on the duration of antibiotic treatment is scarce and the studies do not discriminate between complicated and uncomplicated bacteraemia. (bmj.com)
• In a special article published online in May 2017 by the Journal of the American Geriatrics Society , he describes UTI as an "ambiguous, expansive, overused diagnosis" that can lead to the myriad harms of antibiotic overtreatment. (acpinternist.org)

Antibiotics1

• Methods The INTENSE study is a multicentre, open-label, randomised, pragmatic, phase-IV clinical trial to demonstrate the non-inferiority of a 7-day vs 14-day course for the treatment of uncomplicated enterococcal bacteraemia and incorporating the early switching to oral antibiotics when feasible. (bmj.com)

Detection1

• The study was not powered to look at the effect of draw location on culture positivity, but it raises awareness of an important aspect of bacteremia detection that must be monitored to optimize blood culture yield and contamination rates. (medscape.com)

Abscess1

• Schoenfeld D, Lee D, Arrington JA, Greene J, Klinkova O. Bacillus Cereus bacteremia complicated by brain abscess in a severely immunocompromised patient: Addressing importance of early recognition and challenges in diagnosis. (moffitt.org)

Lemierre's3

• Here, we investigated TTP in 41 patients with F. necrophorum bacteraemia and found an association between short TTP and Lemierre's syndrome (p = 0.026). (lu.se)
• This might delay the diagnosis of conditions such as Lemierre's syndrome, which involves symptoms resembling COVID-19-related throat manifestations. (biomedcentral.com)
• Lemierre's syndrome is frequently accompanied by persistent bacteremia and septic emboli, with the lungs being the most common sites of distant metastasis [ 1 ]. (biomedcentral.com)

Treatment7

• However, when bacteriaare introduced directly into the circulatory system, especially in a personwho is ill or undergoing aggressive medical treatment, the immune system maynot be able to cope with the invasion, and symptoms of bacteremia may develop. (faqs.org)
• The Content is not intended as a substitute for professional medical advice, diagnosis, or treatment. (faqs.org)
• This product/supplement review is not intended to provide diagnosis, treatment, or medical advice. (jointhealthmagazine.com)
• Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. (jointhealthmagazine.com)
• There is an urgent need for a rapid method for detecting bacteremia in pediatric patients with co-morbidities to inform treatment. (listlabs.com)
• To explore senile brucellosis spondylitis clinical features and diagnostic criteria, in order to improve the diagnosis rate and evaluate the clinical effects of treatment strategies. (scirp.org)
• Multidisciplinary approach in diagnosis and treatment of COVID-19-associated mucormycosis: a description of current reports. (moffitt.org)

Acute1

• The data indicated that the potential pathogens identified in the blood samples were associated with translocation from the gut, suggesting the presence of bacteremia, which transcriptome data suggested may induce or aggravate the acute-phase response observed during EVD. (asm.org)

Gonococcal Arthritis1

• In the pediatric population, the diagnosis of gonococcal arthritis must be considered if the patient is sexually active or abused. (medscape.com)

Patients3

• From January 2002 to August 2015, 62 patients with Brucella-associated spondylitis were treated with comprehensive diagnosis based on epidemiological history, clinical manifestations, imaging findings, laboratory tests, and local biopsy. (scirp.org)
• Patients will be thoroughly assessed to confirm their diagnosis through such things as x-rays, blood work, and body fluid testing. (ottawahospital.on.ca)
• Multivariate analysis for predictors of mortality among patients ≥ 80 years, demonstrated higher SOFA score ( odds ratio [OR] 1.36, 95% confidence interval [CI] 1.23-1.51, p corticosteroid therapy (OR 3.15, 95% CI 1.24-8.01, p = 0.016) and hospital acquired P. aeruginosa bacteremia (OR 2.30, 95% CI 1.33-3.98, p = 0.003) as predictors. (bvsalud.org)

Immune1

• People in good healthwith strong immune systems rarely develop bacteremia. (faqs.org)

Infectious1

• Cite this: Two Simple Ways to Improve Diagnosis of Infectious Diseases - Medscape - Mar 15, 2018. (medscape.com)

Blood1

• Bacteremia may cause no symptoms, but may be discovered through a blood testfor another condition. (faqs.org)

Mortality1

• Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. (listlabs.com)

Adults2

• We aimed to evaluate outcomes of P. aeruginosa bacteremia among old adults (≥ 80 years). (bvsalud.org)
• We included the 464/2394 (19%) older adults from a retrospective multinational (9 countries, 25 centers) cohort study of individuals hospitalized with P. aeruginosa bacteremia . (bvsalud.org)

Management1

• In 2015, the National Institute of Child Health and Human Development assembled a workshop to provide evidence-based guidelines for the diagnosis and management of chorioamnionitis. (bmj.com)

Patient1

• Emergent care should focus on making the correct diagnosis and stabilizing the patient. (medscape.com)

Pediatric1

• We conducted a retrospective cohort study using the Pediatric Health Information System database, which we queried for emergency department (ED)-only and hospital encounters between 2012 and 2017 for children aged 2 months to 18 years with diagnosis codes for SSTI. (aap.org)

Intense1

• 38.3°C (100.9°F) is present for most days and the diagnosis is unclear after 1 week of intense investigation. (bmj.com)

Early1

• In this regard, preventive efforts and early diagnosis before organ failure develops might be beneficial for improving outcomes. (bvsalud.org)

Initial diagnosis1

• Anchoring bias is the tendency to focus on an initial diagnosis despite later evidence to the contrary. (ahrq.gov)

Spinal1

• Often, a physician will need to confirm a diagnosis with a spinal tap ( lumbar puncture ), in which a small amount of fluid is extracted from the spinal canal. (nih.gov)