Diabetic retinopathy blood diabetic angiopathies. Medical search. Frequent questions

These findings suggest that LA could be considered an additional factor in the onset and/or progression of diabetic complications, acting as a link between the immunological and haemostatic systems in the pathogenesis of diabetic microangiopathy. (nih.gov)
In addition, individuals with diabetes must make lifestyle changes, such as consuming a healthy diet plan and getting routine workout, to help manage their blood sugar levels and avoid complications. (microqnix.com)
But, if a diabetic patient takes Ayurvedic treatment of diabetes, the chances of complications are less and the condition can be reversed naturally. (deepayurveda.com)
One of the most severe complications of the diabetes mellitus is a diabetic retinopathy, that is a progressive lesion of the retina, requiring laser and surgical intervention. (suaway.com)
Regardless of all usual measures, diet, exercise, surgical care and drug therapy, all complications of diabetic disease are an indication for HBOT. (oxy.hr)
Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. (ox.ac.uk)
OBJECTIVE: To determine whether tight control of blood pressure prevents macrovascular and microvascular complications in patients with type 2 diabetes. (ox.ac.uk)
CONCLUSION: Tight blood pressure control in patients with hypertension and type 2 diabetes achieves a clinically important reduction in the risk of deaths related to diabetes, complications related to diabetes, progression of diabetic retinopathy, and deterioration in visual acuity. (ox.ac.uk)
E08.59 Diabetes mellitus due to underlying condition with other circulatory complications E08.6 Diabetes mellitus due to underlying condition with other specified complications E08.61Diabetes mellitus due to underlying condition with diabetic arthropathy E08.610 Diabetes mellitus due to underlying condition with diabetic neuropathicarthropathy Diabetes mellitus due to underlying … The code E13.59 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions. (workout-transalp.fr)
complications 7 Circulatory None 8 Other specified complications Unspecified complications 9 Unspecified complications We investigated the trend of diabetic vascular complication-related deaths between 2000 and 2016 in the global diabetes … Find out here how to recognize the common symptoms of diabetes. (workout-transalp.fr)
But some may not understand that many of the most common complications of diabetes stem from one primary issue: the havoc that high blood sugar, also called hyperglycemia, causes for the … Possible complications include: Cardiovascular disease. (workout-transalp.fr)
Cardiac autonomic neuropathy (CAN) is one of the most common complications of diabetes, and represents a significant cause of morbidity and mortality in diabetic patients. (e-enm.org)
Diabetic microvasular complications, which are considered as an important group of hyperglycemia imperfections, caused by increased endothelial permeability and can progress to severe impairments in several organs. (scialert.net)
Although diabetic nephropathy, neuropathy and retinopathy are the most common microvascular complications of hyperglycemia, it also affects choroid plexus. (scialert.net)
Connective Tissue Growth Factor (CTGF) has recently been shown to be over-expressed in kidney, myocardium and aorta in diabetic animals, implicating CTGF role in the pathogenesis of both microvascular and macrovascular diabetic complications ( Brownlee, 2001 ). (scialert.net)
Diabetes mellitus (DM) is associated with macrovascular and microvascular complications (coronary artery disease, ischemic stroke, peripheral arterial disease, nephropathy, and retinopathy) [ 1 , 2 ]. (hindawi.com)
Platelets have a "key role" in atherogenesis and its thrombotic complications in subjects with DM [ 3 ], and the concomitant presence of multiple "classical" cardiovascular risk factors (arterial hypertension, cigarette smoking, and hyperlipidemia) in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
They play a role in damaging blood vessels, which can lead to diabetes complications. (diabetes.org)

Diminished blood supply to all organs, particularly to nerves (neuropathy), kidneys (nephropathy), and eye (retinopathy). (what-is-cancer.com)
Many small blood vessels become obstructed ( micro-angiopathy ) and cells die ( necrosis ) which is manifested by retinopathy, nephropathy and neuropathy. (what-is-cancer.com)

In individuals with diabetes, the body's ability to produce or utilize insulin, a hormone that helps to regulate blood sugar levels, suffers diabetic peripheral angiopathy without gangrene. (microqnix.com)
Diabetic polineuropathy: HBOT enhances motoric functions of peripheral nerves and recovery of peripheral sensitivity. (oxy.hr)
Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene: E08.52 Assessment: 66 year old male with diabetic peripheral angiopathy. (workout-transalp.fr)
Hamura turned around diabetic ketoacidosis medications to look at him, and said with national diabetes medical suppliers ccs a smile Okay, you can take charge of Beicheng District, and the rest of the area will be taken care of by other heroes However, your speed is not as treatment for diabetic peripheral angiopathy good as mine and Xiaolongjuan's in this aspect. (moviebill.com)

Mango leaf tea is helpful in treating diabetic angiopathy, diabetic retinopathy and hyperglycemia. (stuffslane.com)
Although all diabetic cells are exposed to elevated levels of plasma glucose, hyperglycemic damage is limited to those cell types that are unable to down regulate glucose transport into the cell (e.g., endothelial cells), leading to intra-cellular hyperglycemia ( Brownlee, 2001 ). (scialert.net)
Primary , marked by hyperglycemia, and a secondary , during which blood vessel changes predominate. (what-is-cancer.com)
When blood glucose rises (hyperglycemia), insulin increases glucose removal, glucagon reduces glucose mobilization, until the original glucose level (normoglycemia) is restored, and vice versa. (what-is-cancer.com)
As diabetes evolves, insulin becomes less effective in removing sugar from blood to tissues and blood glucose level rises (hyperglycemia). (what-is-cancer.com)
Hyperglycemia damages walls of small vessels which supply blood to tissues. (what-is-cancer.com)

This extract also improved diabetic micro-angiopathy and retinopathy. (naturalon.com)

In particular, his studies of diabetic retinopathy, in collaboration with ophthalmological colleagues at UWMS, defined the progression of changes that eventuate in retinal hemorrhages, plaques, exudates, and other lesions producing visual compromise. (wikipedia.org)
In the present study, we demonstrate that following exposure to plasma from diabetic patients, the human promonocytic cell line U937 exhibits a significant elevation in core 2 GlcNAc-T activity and increased adherence to cultured retinal capillary endothelial cells. (diabetesjournals.org)
Diabetic retinopathy is a progressive vision-threatening complication of diabetes, characterized by capillary occlusion, formation of microvascular lesions, and retinal neovascularization adjacent to ischemic areas of the retina ( 1 - 2 ). (diabetesjournals.org)
The exact pathogenic mechanism by which capillary nonperfusion, as demonstrated by fluorescein angiography, occurs is still unclear, but recent experimental animal studies ( 3 - 5 ) demonstrate that increased leukocyte entrapment in retinal capillaries of diabetic rats is an early event associated with areas of capillary nonperfusion and the development of endothelial cell damage. (diabetesjournals.org)
Among the most frequent retinal diseases there are age-related macular degeneration, hereditary retinal degenerations (including retinitis pigmentosa), complicated myopia, diabetic retinopathy. (suaway.com)
In the clinical practice this preparation turned out to be highly effective in the treatment of the aftereffects of retinal veins thrombosis, glaucoma, haemorrhagic retinopathies, retinal sun and laser burns and many other diseases. (suaway.com)
This publication is dedicated to the application of a complex of peptide bioregulators being highly effective in treatment of different retinal diseases (diabetic retinopathy, pigment retinitis, age-related macular degeneration etc. (antiaging-peptides.com)
Diabetic retinopathy (DR), one of the leading causes of blindness and vision impairment, is suggested to exhibit functional and structural changes in retinal neurons as the earliest manifestation, which could be used to predict the progression of related angiopathy. (biomedcentral.com)

He employed histochemistry and ultrastructural studies to assess lesions of the pancreatic islet cells and blood vessels in patients with diabetes mellitus. (wikipedia.org)
This pine bark extract encourages the production of nitric oxide, as well as improved dilation of blood vessels, and increased oxygen levels and blood flow. (naturalon.com)
He said that the leaves contain anti-hypertensive properties which help in strengthening the blood vessels and treating the problem of varicose veins. (guardian.ng)
Ayurvedic Treatment of Diabetes - Diabetes disease is described as a severe and chronic metabolic disorder characterized by elevated levels of blood glucose or blood sugar, which leads over time to serious damage to the blood vessels, eyes, heart, kidneys , and nerves . (deepayurveda.com)
Changes in small blood vessels in DM is strictly specific and characterized by thickening and splitting of the basement membrane of capillaries, venules, arteries, deposition in her gialinopodobnyh substances, fats, proteins, increased permeability of the vascular wall. (rv.ua)
Neuropathy (nerve damage) results from damage to the blood vessels that feed the nerves. (workout-transalp.fr)
Any disease of the blood vessels (veins, arteries, capillaries) or lymphatic vessels. (diabetes.org)
Usually when a tissue requires more resources, blood vessels dilate and bloodflow rises. (what-is-cancer.com)

Diabetic retinopathy in 2% of patients leads to complete blindness. (rv.ua)
Diabetic retinopathy (DR) is a particularly common cause of blindness worldwide. (laser-ophthalmos.com)

Retinopathy is a type of vision loss, especially for diabetic patients, caused by hemorrhages and vascular lesions. (naturalon.com)
Prevention of vascular disorders in diabetic patients using dietary supplements ART LIFE. (rv.ua)
1986 and others), a beneficial effect on the state of the vascular wall, blood rheology. (rv.ua)
It is called angiopathy and it depends on the inadequate or insufficient regulation of diabetes and on the length and type of diabetes combined with the patient's vascular resistance. (laser-ophthalmos.com)
The role of chronic administration of antiplatelet drugs in primary prevention of arterial vascular events is known to be less clear than in secondary prevention, and, also in diabetic patients, the decision to give primary prophylaxis should be taken on an individual-patient basis, after a careful evaluation of the balance between the expected benefits and the risk of major bleedings. (hindawi.com)
Although, currently, treatment has proven useful in reducing vascular events, diabetic patients continue to have a higher risk of adverse cardiovascular events compared with those in nondiabetic patients. (hindawi.com)
This paper reviews the role of currently available antiplatelet drugs in primary and secondary prevention of vascular events in diabetic patients and the limitations of these drugs, and it discusses the role of novel and more potent antiplatelets and of new agents currently under clinical development. (hindawi.com)

The IGF system has been associated with development and progression of diabetic retinopathy. (diabetesjournals.org)
We examined whether a simple measurement of the IGF system (serum total IGF-I) correlated with progression of diabetic retinopathy in pregnancy in type 1 diabetes. (diabetesjournals.org)
Serum IGF-I increased with increasing progression of retinopathy. (diabetesjournals.org)
Pregnancy is a prominent risk factor for the development and progression of retinopathy in women with type 1 diabetes. (diabetesjournals.org)
Progression of retinopathy has been reported to be associated with suboptimal regulation of blood glucose and blood pressure, albuminuria, and adverse perinatal outcomes. (diabetesjournals.org)
However, after it was shown that pituitary ablation could halt the progression of proliferative diabetic retinopathy, increased focus has been put on the hormonal changes with growth-stimulating potential that accompanies pregnancy ( 1 ). (diabetesjournals.org)
Although some regression of nonproliferative retinopathy occurs after delivery, new cases with progression of retinopathy during pregnancy have been reported with a prevalence ranging between 20 and 85% ( 3 - 5 ). (diabetesjournals.org)
The aim of the present study was to examine the correlation between serum IGF-I and progression of retinopathy in diabetic pregnancy in 103 pregnant women with type 1 diabetes. (diabetesjournals.org)
Changes in serum IGF-I and progression of retinopathy, as well as their time course during and after pregnancy, were studied in a cross-sectional manner. (diabetesjournals.org)

Can mango leaves cure diabetes, high blood pressure? (guardian.ng)
The plant pathologist said that mango leaves could also be used in treating high blood pressure. (guardian.ng)
Mango leaves contain tannins called anthocyanins, which help treat diabetes, as they help lower blood sugar, which is why it is also used in the treatment of angiopathy or diabetic retinopathy. (theyucatantimes.com)
Mango leaves contain tannins and anthocyanins which have the capability to improve insulin production, regulate blood sugar levels, manage diabetes (Type 2 diabetes), and relieve the symptoms of diabetes such as frequent urination at night, and help treating angiopathy and retinopathy diabetes. (africacheck.org)
Some studies have documented some anti-diabetic properties of mango extracts. (africacheck.org)

For people with type 2 diabetes, treatment might consist of lifestyle changes such as weight-loss and regular exercise, as well as oral medications to help control blood glucose levels. (microqnix.com)
SGLT2 inhibitors: These drugs block the reabsorption of glucose by the kidneys, which assists to lower blood glucose levels. (microqnix.com)
Blood glucose levels at presentation may be below those typically expected for diabetic ketoacidosis (eg, less than 250 mg/dL). (janssencarepath.com)
Assess for ketoacidosis regardless of presenting blood glucose levels in patients who present with signs and symptoms consistent with severe metabolic acidosis. (janssencarepath.com)
When these cells fail to respond adequately to circulating insulin, blood glucose levels rise. (thediabeticpharmacist.com)
Elevated blood fatty-acid concentrations (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. (thediabeticpharmacist.com)
Optimal diabetic control requires frequent self-monitoring of blood glucose levels, which allows rational adjustments in insulin doses. (medscape.com)
All patients with type 1 diabetes should learn how to self-monitor and record their blood glucose levels with home analyzers and adjust their insulin doses accordingly. (medscape.com)
Most require 2 or more injections of insulin daily, with doses adjusted on the basis of self-monitoring of blood glucose levels. (medscape.com)

Although these medicines are effective in treating … 172 - 174 In a retrospective study of >700 000 Veterans Affairs patients, using International Classification of Diseases-9 codes to identify diabetes mellitus, the risk of pulmonary embolism was 27% higher in the diabetic … It is characterized by high levels of sugar in the blood. (workout-transalp.fr)
5. Polymorphism of the angiotensin I-converting enzyme gene in diabetic retinopathy patients and type 2 diabetes mellitus patients with myocardial infarction. (klinika-tverskaya.ru)
In patients with type 1 diabetes mellitus, INVOKANA ® significantly increases the risk of diabetic ketoacidosis, a life-threatening event, beyond the background rate. (janssencarepath.com)

Lower-limb infections, gangrene, and diabetic foot ulcers were the most common precipitating medical events leading to the need for an amputation. (janssencarepath.com)

Levels of enzyme activity in plasma-treated U937 cells were closely dependent on the severity of diabetic retinopathy, with the highest values observed upon treatment with plasma of patients affected by proliferative retinopathy. (diabetesjournals.org)

It turned out that peptide bioregulators are most effective in case of age-related macular degeneration, retinitis pigmentosa, complicated myopia, diabetic retinopathy. (suaway.com)

Precipitating conditions for diabetic ketoacidosis or other ketoacidosis include acute febrile illness, reduced caloric intake, ketogenic diet, surgery, insulin dose reduction, volume depletion, and alcohol abuse. (janssencarepath.com)
It is not unusual for patients with type 1 diabetes to present with diabetic ketoacidosis (DKA). (medscape.com)

His experimental studies in dogs showed that meticulous control of glucose metabolism could effectively prevent diabetic angiopathy. (wikipedia.org)

Recent studies have shown that diabetic microangiopathies are associated with macroangiopathies and suggest that microangiopathies may have a prominent role in the pathogenesis of microangiopathy development [ 2 ]. (e-enm.org)

Some of these secondary health issues may present themselves in consistently elevated blood sugars, dark urine, nausea/vomiting, spotty vision and more. (workout-transalp.fr)
Aassociations between carotid atherosclerosis and both urine albumin excretion (UAE) and glomerular filtration rate (GFR) in diabetic patients have been investigated, but these studies showed only inconsistent results [ 5 , 13 , 14 ]. (e-enm.org)
Blood sugar rises and is spilled out into the urine. (what-is-cancer.com)

Treating these problems with pine bark extract helped to strengthen capillaries and stop blood leakage into the retina. (naturalon.com)
Growth hormone (GH) exerts many of its effects via the synthesis and release of IGF-I. IGF-I has been variably associated with diabetic microvascular disease, and a transient rise in IGF-I has been reported in the early phase of neovascularization of the retina ( 2 ). (diabetesjournals.org)
Position of the retina behind other optic structures, direct ingress of sun rays, peculiarities of the blood supply make it vulnerable to both external (sun rays, light striking, radiation) and internal factors. (suaway.com)
Diabetic retinopathy and maculopathy: HBOT lessens or changes the need for laser photocoagulation that leaves permanent scars on retina. (oxy.hr)

This pine bark extract was also noted in another study, published in the journal of Clinical and Applied Thrombosis and Hemostasis, which helped to improve overall blood circulation as well as minimize edema. (naturalon.com)

The prevalence of increased urinary albumin excretion (UAE) (micro- and macroalbuminuria) and its association with diabetic retinopathy (DR) (evaluated by fluorescent angiography), coronary heart disease (CHD), and various related risk factors were studied in 320 type 2 diabetic patients. (nih.gov)
We conclude that increased UAE is associated to a greater frequency of retinopathy and CHD in type 2 diabetic patients. (nih.gov)
The aim of this study was to evaluate if endothelial dysfunction and unmodulated haemostasis are amplified by the presence of LA in Type 1 diabetic patients. (nih.gov)
Plasma samples collected from clinically and biochemically well-characterized Type 1 diabetic patients were examined for LA, fibrinogen, prothrombin (PT), PTT, prothrombin degradation products (F1 + 2) and activated protein C (APC). (nih.gov)
For people with type 1 diabetes, treatment includes daily insulin injections and tracking of blood sugar level levels. (microqnix.com)
In this type, body cells cannot use blood sugar efficiently for energy. (deepayurveda.com)
A person who has blood pressure over 140/90 mm Hg is at great risk of having type 2 diabetes. (deepayurveda.com)
A close relationship between poor glycemic control and increased platelet activity (estimated by measuring mean platelet volume-MPV-as part of whole blood count) in patients with type 2 DM has been suggested [ 4 ]. (hindawi.com)
C57BLKsJ-db/db (db/db) mice (a type 2 diabetic mouse model) were used with their normoglycemic heterozygous littermates (db/+) serving as controls. (biomedcentral.com)
If this compensatory increase does not occur, blood glucose concentrations increase and type 2 diabetes occurs. (thediabeticpharmacist.com)

Based on the prominent role of TNF-α in the development of diabetic retinopathy, these observations further validate the significance of core 2 GlcNAc-T in the pathogenesis of capillary occlusion, thereby enhancing the therapeutic potential of specific enzyme inhibitors. (diabetesjournals.org)

This paper highlights the underlying pharmacological mechanisms of the anti-diabetic effects of ginsenosides. (frontiersin.org)

Many people with hypertension are either diabetic or pre-diabetic and have elevated insulin levels due to insulin resistance. (thediabeticpharmacist.com)

Diabetes is a chronic metabolic disease which leads to high blood sugar because the body does not make enough insulin, or does not use the insulin it produces properly. (africacheck.org)
Medicine presumes that diabetes is initiated by a random metabolic error , loss of blood glucose control due to a malfunction of insulin . (what-is-cancer.com)

We recently reported that raised activity of the glycosylating enzyme core 2 β 1,6- N -acetylglucosaminyltransferase (GlcNAc-T) through protein kinase C (PKC)β2-dependent phosphorylation plays a fundamental role in increased leukocyte-endothelial cell adhesion and capillary occlusion in retinopathy. (diabetesjournals.org)

Cardiovascular (CV) diseases are the leading cause of morbidity and mortality in diabetic patients. (hindawi.com)

Tomsk and Voronezh have been studied biologically active food additives (BAA) MEMORY RISE (production company ARTLIFE ) for the prevention and treatment of diabetic angiopathies, including diabetic foot. (rv.ua)
The US-based Centers for Disease Control and Prevention say diabetes can be managed with a healthy diet, insulin and other injectable oral medications, to help manage blood sugar, blood pressure and cholesterol levels. (africacheck.org)

Object: To evaluate antidiabetic activity of ethanolic extract of Holostemma ada Kodien Schults (EEHK) in normal, glucose fed ,alloxan-induced diabetic rats and to perform phytochemical and toxicity studies. (ac.ke)

Insulin resistance in muscle and fat cells reduces glucose uptake (and also local storage of glucose as glycogen and triglycerides , respectively), whereas insulin resistance in liver cells results in reduced glycogen synthesis and storage and a failure to suppress glucose production and release into the blood. (thediabeticpharmacist.com)

In the multivariate analysis, initial hearing thresholds of affected ear and timing of steroid treatment were significantly associated with hearing prognosis in diabetic patients with SSNHL. (ejao.org)

Moreover, the concomitant presence of multiple "classical" cardiovascular risk factors in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)

Simultaneous intratympanic dexamethasone (ITD) injections with systemic steroid did not confer an additional hearing gain or an earlier recovery rate in diabetic patients with SSNHL. (ejao.org)
Simultaneous ITD injections to improve hearing recovery in diabetic patients with SSNHL seems unnecessary. (ejao.org)

A large body of evidence now implicates increased leukocyte-endothelial cell adhesion as a key early event in the development of diabetic retinopathy. (diabetesjournals.org)

This study primarily aimed to investigate mitochondrial functional changes in a diabetic rodent model. (biomedcentral.com)

For the analysis of the anti-inflammatory study human blood was used, the inflammatory test was carried by the Hemolysis Inhibition Assay, post the analysis the extract showed potential to inhibit the breakdown of red blood cells. (ikprress.org)
The women were scheduled for ophthalmologic examination, including visual acuity testing and fundus photography, before pregnancy, once in each trimester, and 4 months after birth, according to the principles defined in the Early Treatment for Diabetic Retinopathy Study ( 6 ). (diabetesjournals.org)
This study aimed to evaluate the clinical features and the clinical factors associated with prognosis of sudden sensorineural hearing loss (SSNHL) in diabetic patients. (ejao.org)
After nine years of follow up the group assigned to tight blood pressure control also had a 34% reduction in risk in the proportion of patients with deterioration of retinopathy by two steps (99% confidence interval 11% to 50%) (P=0.0004) and a 47% reduced risk (7% to 70%) (P=0.004) of deterioration in visual acuity by three lines of the early treatment of diabetic retinopathy study (ETDRS) chart. (ox.ac.uk)

Therefore, we conducted a retrospective review to evaluate the clinical factors associated with prognosis and compare the efficacy of simultaneous and sequential systemic steroid and ITD treatment in diabetic patients with SSNHL. (ejao.org)
Also, we evaluated the clinical features of SSNHL in diabetic patients including the laboratory data which are known to be related to systemic inflammation and glycemic control. (ejao.org)
The role of novel and more potent antiplatelet strategies, currently under clinical development, seems attractive in diabetic patients. (hindawi.com)

Patients should be aware that if they do not carefully regulate their blood sugar level, then the prognosis of DR is not good, regardless of the laser treatment applied. (laser-ophthalmos.com)

It is very important to maintain a normal level of activity indicators of the blood coagulation system. (rv.ua)

Although the precise underlying mechanisms linking the diabetic microangiopathies and macroangiopathies are unclear, some evidence suggests that the effects of microangiopathies may be linked to subclinical atherosclerosis [ 3 - 5 ]. (e-enm.org)
Carotid atherosclerosis as estimated by carotid intima-media thickness (CIMT) and plaques is considered to reflect an early stage of atherosclerotic disease and is therefore used as a surrogate marker for diabetic macroangiopathies [ 6 - 8 ]. (e-enm.org)
So far, studies on the relationship between diabetic microangiopathies and carotid atherosclerosis have yielded inconsistent results. (e-enm.org)

Symptoms are dependent on how much blood sugar is elevated in a person. (deepayurveda.com)
These effects of diabetic plasma on enzyme activity and cell adhesion, mediated by PKCβ2-dependent phosphorylation of the core 2 GlcNAc-T protein, were found to be triggered by increased plasma levels of tumor necrosis factor (TNF)-α. (diabetesjournals.org)

Insulin: Insulin is a hormonal agent that assists to regulate blood sugar level levels. (microqnix.com)

Anatomy26

Organisms4

Diseases47

Chemicals and Drugs32

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Psychiatry and Psychology1

Phenomena and Processes9

Disciplines and Occupations5

Information Science3

Named Groups2

Health Care15

Geographicals3

Complications18

Nephropathy2

Peripheral4

Hyperglycemia6

Micro-angiopathy1

Retinal8

Vessels8

Blindness2

Vascular7

Progression9

Mango5

Glucose levels9

Diabetes mellitus3

Gangrene1

Proliferative1

Macular degeneration1

Ketoacidosis2

Metabolism1

Microangiopathy1

Urine3

Retina4

Thrombosis1

Type10

Pathogenesis1

Anti-diabetic1

Hypertension1

Metabolic2

Occlusion1

Diseases1

Prevention2

Rats1

Insulin resistance1

Significantly associated1

Cardiovascular1

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Study4

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Regulate1