• Proliferative diabetic retinopathy (PDR) accounts for severe impact on vision, its mechanism is still poorly understood. (frontiersin.org)
  • Diabetic retinopathy (DR) is the leading cause of blindness among working age people ( 1 - 4 ). (frontiersin.org)
  • The worldwide prevalence of DR has been estimated to be 34.6% in patients with diabetes, and the prevalence of vision-threatening DR, such as proliferative diabetic retinopathy (PDR) has been estimated to be 6.96% ( 5 ). (frontiersin.org)
  • An important innovation in the treatment of diabetic retinopathy (DR) and diabetic macular edema (DME), anti-VEGF agents can preserve visual acuity and even significantly improve vision in most patients with DME. (crstoday.com)
  • A Diabetic Retinopathy Clinical Research Network (DRCR.net) study in patients with DME and baseline visual acuity of 20/50 or worse demonstrated that patients receiving ranibizumab or aflibercept had better outcomes than those receiving bevacizumab, but all three agents offered significant visual and anatomic improvements over focal laser treatment. (crstoday.com)
  • 15 Diabetic patients with cataracts 16 or retinopathy 15 may be unable to properly examine their feet regularly. (diabetesjournals.org)
  • The Diabetic Retinopathy within the Regional Eye Centre at the National Referral Hospital is encouraging diabetic patients to a regular eye check. (com.sb)
  • Diabetic Retinopathy Officer, Edith Fanega explains, people must understand that diabetes can affect patients eyes. (com.sb)
  • Our general physicians would need detailed training if they are to be involved in early detection of diabetic retinopathy. (who.int)
  • However, there are nearly 35 000 people diagnosed with diabetes in the 1.9 million Omani population who would need frequent eye check-ups to rule out complications, mainly diabetic retinopathy [3]. (who.int)
  • Diabetic retinopathy is the fifth leading cause of blindness worldwide accounting for nearly 5% of all blindness. (ajol.info)
  • The study sought to determine the prevalence of, and factors associated with, retinopathy in diabetic patients. (ajol.info)
  • Longer duration of diabetes mellitus and lower serum creatinine, which is a marker of renal damage, were independent risk factors of diabetic retinopathy. (ajol.info)
  • Diabetic retinopathy , which is the leading cause of blindness in American adults. (medlineplus.gov)
  • This usually develops in people who already have other signs of diabetic retinopathy. (medlineplus.gov)
  • The US Food and Drug Administration (FDA) has approved aflibercept ( Eylea , Regeneron) injection solution to treat all stages of diabetic retinopathy, the manufacturer has announced. (medscape.com)
  • Millions of people have been robbed of their vision due to the progression of diabetic retinopathy," David Brown, MD, director of research at Retina Consultants of Houston, Texas, said in a company news release. (medscape.com)
  • The prevention of worsening diabetic retinopathy with Eylea provides a compelling rationale for early treatment of patients with this disease, particularly since eyes dosed with Eylea as infrequently as every 16 weeks showed significant improvements in the pivotal PANORAMA trial," said Brown. (medscape.com)
  • The FDA approved aflibercept for diabetic retinopathy based on 6-month and 1-year results from the phase 3 PANORAMA trial, which investigated aflibercept for improvement of moderately severe to severe nonproliferative diabetic retinopathy without diabetic macular edema compared with sham injection. (medscape.com)
  • In fact, 80% of patients who received the Eylea 8-week dosing regimen had significant improvement in their diabetic retinopathy," George Yancopoulos, MD, PhD, president and chief scientific officer at Regeneron, said in the release. (medscape.com)
  • Safety data from 269 patients with nonproliferative diabetic retinopathy through the first year were in line with the phase 3 VIVID and VISTA trials. (medscape.com)
  • The recommended dose for aflibercept in patients with diabetic retinopathy is 2 mg (0.05 mL) administered by intravitreal injection every 4 weeks (approximately every 28 days, monthly) for the first five injections followed by 2 mg (0.05 mL) by intravitreal injection once every 8 weeks (2 months). (medscape.com)
  • Cite this: FDA OKs Aflibercept (Eylea) for Diabetic Retinopathy - Medscape - May 14, 2019. (medscape.com)
  • It occurs typically before the age of 30 in patients with good vision and mild non‐proliferative diabetic retinopathy. (wikipedia.org)
  • Furthermore, people with diabetes are at increased risk for visual loss due to diabetic retinopathy, glaucoma, and cataracts. (cdc.gov)
  • However, since patients with retinopathy are usually asymptomatic at the most treatable stage of their disease, they may not seek an examination at that time. (cdc.gov)
  • Laser photocoagulation therapy is effective in reducing the risk of visual loss in patients with high-risk proliferative retinopathy and clinically significant macular edema. (cdc.gov)
  • Cystic fibrosis (CF) related diabetes is an increasingly common comorbidity in CF patients, with scarce data on end-stage complications in the CF population. (nih.gov)
  • To our knowledge, this is the first reported case of diabetic myonecrosis in a patient with CF, and highlights the need for pulmonary physicians to recognize this diabetic complication in CF patients, which is associated with a poor long-term prognosis and existing microvascular complications. (nih.gov)
  • With the increasing prevalence of diabetic patients undergoing surgery, and the increased risk of complications associated with diabetes mellitus, appropriate perioperative assessment and management are imperative. (medscape.com)
  • Infections account for 66% of postoperative complications and nearly one quarter of perioperative deaths in patients with DM. (medscape.com)
  • In addition to postoperative infectious complications, postoperative myocardial ischemia is increased among patients with DM undergoing cardiac and noncardiac surgery. (medscape.com)
  • Only 29 % of the patients reach the recommended goals for treatment to prevent disabling late diabetes complications. (news-medical.net)
  • Although peritoneal dialysis (PD) is becoming more widespread, PD among diabetic patients carries some concerns, such as worsened glycemic control due to constant exposure to glucose and operational errors due to diabetic complications. (springer.com)
  • This study investigates whether, compared to standard treatment, immediate restoration of blood flow (revascularization) can reduce complications and improve diabetic foot ulcer healing. (centerwatch.com)
  • To prevent severe foot burn injuries, continuous education should be provided for diabetic patients with sensory loss of the lower extremities due to neuropathic complications. (medscimonit.com)
  • It can be challenging for cataract and refractive surgeons to answer patient questions about possible ocular complications and how they are treated. (crstoday.com)
  • It is more than a cosmetic problem, and diabetic patients have a greater risk of serious complications from the disease, including limb amputations. (diabetesjournals.org)
  • 13 Because onychomycosis in diabetic patients can lead to many complications,most insurance companies cover treatment in documented cases. (diabetesjournals.org)
  • Educating these patients, improving their socioeconomic status will help them modify behaviours and identify foot at risk and complications. (scirp.org)
  • Poor glycaemic control, dyslipidaemia and HT are common in diabetic children, putting them at risk of cardiovascular complications in adulthood. (who.int)
  • Patients with an infected diabetic foot ulcer have a far worse prognosis than previously thought, with 15% of patients dying within a year, less than half of the ulcers healing in the same time period, and one in seven individuals having all or part of their foot amputated, results from a new UK study reveal. (medscape.com)
  • The analysis of almost 300 patients with infected diabetic foot ulcers also showed that, even if the ulcer healed, nearly 10% experienced a recurrence within 12 months and more than 25% of patients underwent some kind of procedure. (medscape.com)
  • Patients with diabetic neuropathy often can't feel injuries on their feet, which can lead to ulcers and amputation. (allaboutcircuits.com)
  • Currently, Ma explains, doctors must manually check their patients' feet for ulcers. (allaboutcircuits.com)
  • Siren feels confident that these smart socks can give patients peace of mind in between doctor visits, especially since ulcers can take only hours or days to develop. (allaboutcircuits.com)
  • Siren says its Neurofabric has the potential to be about 87% more effective in treating diabetic foot ulcers than conventional methods. (allaboutcircuits.com)
  • BUFFALO, N.Y. - Suramin, a 100-year old drug used to treat sleeping sickness, has been repurposed to fight oral mucositis and diabetic foot ulcers, according to University at Buffalo-supported research. (buffalo.edu)
  • Oral mucositis - or ulcers and sores of the mouth and throat - is a common side effect of chemotherapy and radiation in patients with head and neck cancer. (buffalo.edu)
  • People with diabetes face a similar problem: diabetic foot ulcers. (buffalo.edu)
  • These ulcers, the most common complication that diabetic patients experience, directly result in 85% of diabetes-related amputations, according to the American College of Physicians. (buffalo.edu)
  • Due to lower extremity arterial disease (LEAD), diabetic patients with foot ulcers often require lower limb amputation. (centerwatch.com)
  • The aim of this study is to demonstrate that in patients with low grade arterial disease of the lower extremities and diabetic foot ulcers, immediate revascularization results in fewer cardiovascular problems and amputations, as well as improved ulcer healing, compared to the current standard of care. (centerwatch.com)
  • Diabetic macular edema (DME) , which happens when blood vessels in the retina leak fluid into the macula (a part of the retina needed for sharp, central vision). (medlineplus.gov)
  • Aflibercept, a vascular endothelial growth factor (VEGF) inhibitor, is already approved in the United States for neovascular (wet) age-related macular degeneration, macular edema after central retinal vein occlusion, and diabetic macular edema . (medscape.com)
  • Current therapies for diabetes are not efficient preventing the progression of diabetic nephropathy to kidney failure, but in a new study published in the Journal of the American Society of Nephrology (JASN), researchers evaluated a new strategy. (pharmacytimes.com)
  • We investigated the correlation between zinc levels and Nrf2 expression and potential effects on the clinicopathology of patients with diabetic nephropathy (DN). (nature.com)
  • A decrease in the number and dysfunction of endothelial progenitor cells (EPC) may increase the risk for progression of cardiovascular disease (CVD) in type 1 diabetic patients with diabetic nephropathy (DN). (ku.dk)
  • Moreover, HCV patients with insulin resistance, with or without diabetes, have a poor response to antiviral treatment, increased progression of liver fibrosis and greater risk of developing liver cancer (hepatocellular carcinoma). (sciencedaily.com)
  • Similar to the group's prior study, Black and Hispanic patients were less likely than whites to be using continuous glucose monitoring or an insulin pump. (medpagetoday.com)
  • Thus, elderly patients usually treated with oral agents may need to be treated temporarily with insulin. (health.am)
  • Sliding scales of regular insulin can be useful for the acutely ill patient or postoperative patient who is unable to eat. (health.am)
  • in particular, diabetic patients treated with insulin had a threefold higher mortality risk compared to nondiabetic patients, while diabetic patients not treated with insulin had only a modestly and nonsignificantly higher mortality risk (HR 1.59) compared to nondiabetic patients with HF [ 22 ]. (hindawi.com)
  • Therefore, we studied the erythrocyte sialic acid content and hemorheological parameters in well controlled non-insulin dependent type 2 diabetic patients (17 non-obese and 19 obese). (iospress.com)
  • 1. Microvascular blood flow responses to injury and capillary ultrastructure were assessed by laser Doppler flowmetry and detailed light and electron microscopy respectively in skin biopsied from 28 patients with insulin-dependent diabetes and 17 control subjects. (portlandpress.com)
  • Patients with type 1 diabetes need to inject insulin to survive. (plos.org)
  • All patients should be informed (a) that sight-threatening eye disease is a common complication of diabetes mellitus and can often be present even with good vision and (b) that early detection and appropriate treatment of diabetic eye disease greatly reduce the risk of visual loss. (cdc.gov)
  • Further quantitative, qualitative or mixed methods research is needed to more fully understand common experiences of pain in patients with DPNP, and the common meanings ascribed to these experiences. (researchgate.net)
  • Patients and methods: An audit of consecutive patients who were referred and had amputation as a result of diabetic foot diseases in a tertiary institution in Sokoto, northwest Nigeria over a 2-year period was done. (scirp.org)
  • Methods: We examined EPC numbers in 37 type 1 diabetic patients with DN and 35 type 1 diabetic patients with long-standing normoalbuminuria. (ku.dk)
  • RESEARCH DESIGN AND METHODS -A heterogeneous sample of 363 type 2 diabetic patients completed the original Patient Assessment of Chronic Illness Care (PACIC), along with additional items that allowed it to be scored according to the "5As" (ask, advise, agree, assist, and arrange) model of behavioral counseling. (diabetesjournals.org)
  • Review patient evaluation methods that can be used to identify the most appropriate treatment options for chronic pain. (cdc.gov)
  • Mortality rates in diabetic patients have been estimated to be up to 5 times greater than in nondiabetic patients, often related to the end-organ damage caused by the disease. (medscape.com)
  • Different studies have shown a different prognosis in T2DM patients and T2DM elderly patients treated by CRT-D. We reviewed the literature data on CRT-D effect on adult and elderly patients with T2DM as compared with nondiabetic patients. (hindawi.com)
  • Therefore, we reviewed the literature data on CRT effect on adult and elderly patients with T2DM as compared with nondiabetic patients. (hindawi.com)
  • Onychomycosis is more common in diabetic than nondiabetic patients. (diabetesjournals.org)
  • The ultimate goal in the management of diabetic patients is to achieve outcomes equivalent to those in patients without DM. (medscape.com)
  • 2015 Guidelines on the management of diabetic patients. (viamedica.pl)
  • Albrecht von Graefe's archive for clinical and experimental ophthalmology JO - Albrecht Von Graefes Arch Klin Exp Ophthalmol VL - 206 IS - 1 N2 - Preoperative iris fluorescein angiograms (IFA) and ophthalmic records of 34 diabetic patients who underwent vitrectomy were reviewed. (unboundmedicine.com)
  • In a cross-sectional study of 180 with type 1 diabetes and lab-confirmed COVID-19 infection, Black and Hispanic patients were significantly more likely to also present with diabetic ketoacidosis than white patients, Osagie Ebekozien, MD, MPH, of the T1D Exchange in Boston, and colleagues wrote in the Journal of Clinical Endocrinology & Metabolism . (medpagetoday.com)
  • In patients under optimal medical therapy with moderate to severe HF and cardiac dyssynchrony, cardiac resynchronization therapy (CRT) with a defibrillator improves contractile function and reverse ventricular remodeling, ameliorating symptoms, quality of life (QoL), and clinical outcomes [ 7 , 8 ]. (hindawi.com)
  • In literature the most relevant studies and clinical trials on CRT-D clinical outcomes regard enrolled patients with mean age under 70 years. (hindawi.com)
  • We detected the levels of zinc, copper, and Nrf2 mRNA in their serum, and collected the clinical and pathological data of DN patients. (nature.com)
  • Additionally, DN patients with zinc deficiency were prone to have more severe clinical and pathological manifestations. (nature.com)
  • In this study, we sought to determine whether zinc deficiency affected Nrf2 expression in patients with DN and to ascertain the clinical and pathological features of DN patients with zinc deficiency. (nature.com)
  • Clinical Implications: Pain in patients with DPNP involves a range of threatening pain sensations, including sensations with burning, shooting, tingling, or cramping qualities, and additional more cognitive meanings linked to persistent pain, including a sense that pain disrupts daily life in an intrusive way. (researchgate.net)
  • Given the heavy personal burden that DPNP imposes on patients and the considerable challenge of managing the condition pharmacologically, clinical use of non-pharmacological therapies such as CBT for painful diabetic neuropathy might be warranted in individual patients. (researchgate.net)
  • Nilanjan Ghosh et al, Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease, Molecular Therapy-Nucleic Acids (2022). (medicalxpress.com)
  • Eligible patients were aged between 18 and 80 years, had a confirmed diagnosis of diabetes with acceptable glycemic control, had been receiving established diabetic therapy for at least 3 months, and had a clinical diagnosis of distal symmetric sensory neuropathy with daily DPN-associated pain for the previous 3 months. (nih.gov)
  • Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease. (otago.ac.nz)
  • Severe clinical consequences of foot burn injuries of unusual etiology may occur in diabetic patients with neuropathy. (medscimonit.com)
  • Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St. (medscimonit.com)
  • PLOS Medicine publishes research and commentary of general interest with clear implications for patient care, public policy or clinical research agendas. (plos.org)
  • Then, it is important to evaluate psychological aspects that could interfere with the comprehension of the procedure being a clinical study with uncertain results, and with patient adherence at all stages of the project. (bvsalud.org)
  • These are the two main clinical features that differentiate diabetic papillopathy from anterior ischemic optic neuropathy. (wikipedia.org)
  • The pedicled flap combined with membrane induction technique for repairing foot and ankle wounds in diabetic patients has the advantage of simple operation, preserved ankle joint function, and less postoperative infection recurrence , which is worth popularizing in clinical practice. (bvsalud.org)
  • From March 2019 to July 2021, 12 patients with diabetic foot and ankle wounds who met the inclusion criteria were admitted to Wuxi Ninth People's Hospital , including 7 males and 5 females , aged 20 to 92 years. (bvsalud.org)
  • In selected patients affected by HF and severe dysfunction of left ventricle ejection fraction (LVEF), with left bundle brunch block, the cardiac resynchronization therapy with a defibrillator (CRT) is the treatment of choice to improve symptoms, NYHA class, and quality of life. (hindawi.com)
  • Patients with infection-related diseases, malignant tumors, severe hypertension, and severe liver dysfunction were excluded. (nature.com)
  • We previously reported that preoperative IVR treatment in patients with severe PDR contributes to a decreased risk of postoperative neovascular glaucoma ( 11 ), and found further changes in vitreous protein profiles of PDR patients treated with and without IVR ( 12 ). (frontiersin.org)
  • Diagnosing whether or not a diabetic foot ulcer is infected can be difficult, especially in the presence of limb ischemia or peripheral neuropathy, the researchers note, but it is generally agreed that this decision should be based on signs or symptoms of inflammation or purulence. (medscape.com)
  • This week, medical device company Siren raised $11.8 million in funding for a smart wearable on course to change the lives of patients with diabetic neuropathy. (allaboutcircuits.com)
  • The Mayo Clinic explains that diabetic neuropathy can cause nerve damage , most often in the legs and feet, resulting in less sensation in those areas. (allaboutcircuits.com)
  • Ma she wanted to create a wearable that took a preventative approach to diabetic neuropathy. (allaboutcircuits.com)
  • Introduction: Diabetic peripheral neuropathy (DPN) affects almost 30% to 50% of patients with diabetes, 40% to 60% of whom suffer from diabetic peripheral neuropathic pain (DPNP). (researchgate.net)
  • Pain associated with diabetic peripheral neuropathy (DPN) has a substantial negative impact on patients' quality of life. (nih.gov)
  • Preliminary efficacy assessments included changes from baseline in scores on the pain intensity rating scale (PIRS), pain relief rating scale (PRRS), peripheral neuropathy quality-of-life instrument, and patients' diary assessments of sleep, present pain intensity, pain, and activity. (nih.gov)
  • Diabetic papillopathy has many characteristics similar to Non-arteritic anterior ischemic optic neuropathy (NAION). (wikipedia.org)
  • Fast Five Quiz: How Much Do You Know About Diabetic Neuropathy? (medscape.com)
  • For more on the risk factors for diabetic neuropathy, read here . (medscape.com)
  • Conclusions: Amputation was commonly done in the female diabetic housewife with no formal education. (scirp.org)
  • Conclusions: Asymptomatic patients with DN had EPC numbers similar to normoalbuminuric patients, which was related to aggressive CVD intervention therapy. (ku.dk)
  • CONCLUSIONS -The PACIC and the new 5As scoring method appear useful for diabetic patients. (diabetesjournals.org)
  • Background: Diabetic foot disease is a foot that exhibits any pathology that results directly from diabetic mellitus or any long-term chronic complication of diabetes mellitus. (scirp.org)
  • Diabetic papillopathy (also known as diabetic papillitis) is an ocular complication of diabetes mellitus characterized by optic disc swelling and edema of optic nerve head. (wikipedia.org)
  • Diabetic tractional retinal detachments are challenging to address in surgery. (crstoday.com)
  • Patients should be referred to an ophthalmologist promptly for unexplained visual symptoms, reduced corrected visual acuity, increased intraocular pressure, any retinal abnormalities, or any other ocular pathology that threatens vision. (cdc.gov)
  • Vitrectomy can restore vision in certain patients with recent traction retinal detachment and/or vitreous hemorrhage. (cdc.gov)
  • Fifty-two (17.4%) of patients had amputation of some part of the foot during follow-up, 18 (6.0%) underwent peripheral revascularization, and 10 (3.3%) underwent both procedures. (medscape.com)
  • A Forbes article on Siren socks explains that the wearables underwent heavy testing among patients experiencing Type 1, Type 2, and gestational diabetes in the United States and Canada. (allaboutcircuits.com)
  • Patients who met the inclusion criteria underwent a 2-week washout period during which all analgesics were discontinued, followed by 29 days of treatment with capsules containing DM 30 mg and Q 30 mg (DM30/Q30), beginning with 1 capsule/d and escalating at approximately 1-week intervals, as tolerated, to a maximum dose of 4 capsules/d (DM120/Q120). (nih.gov)
  • 4 Male diabetic patients have a three times higher risk of onychomycosis than female diabetic patients. (diabetesjournals.org)
  • Researchers reveal that antiviral therapy for hepatitis C virus (HCV) improves kidney and cardiovascular outcomes for patients with diabetes. (sciencedaily.com)
  • Results show that incidences of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus. (sciencedaily.com)
  • Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that incidents of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus. (sciencedaily.com)
  • But these issues are mitigated by HCV antiviral therapy, specifically pegylated interferon plus ribavirin, which was found to reduce risks of kidney disease, stroke and cardiovascular diseases in diabetic patients," concludes Dr. Wu. (sciencedaily.com)
  • Researchers developed a new approach that may help stop the progression of kidney disease in individuals with diabetes, a condition that affects about one-third of diabetic patients. (pharmacytimes.com)
  • It also slowed the progression of kidney disease in diabetic mice. (pharmacytimes.com)
  • Dialysis modality choice in diabetic patients with end-stage kidney disease: a systematic review of the available evidence. (springer.com)
  • Chonchol M, Cigolini M, Targher G. Association between 25-hydroxyvitamin D deficiency and cardiovascular disease in type 2 diabetic patients with mild kidney dysfunction. (medscape.org)
  • Dr Nelson emphasized that patients who undergo amputations generally have a lower quality of life than those who avoid this outcome and that having one amputation indicates a higher likelihood of a subsequent amputation because it signifies a poor vascular supply. (medscape.com)
  • Achieving arterial supply (revascularization) to the ulcer is the most important factor in healing the diabetic foot ulcer and reduces the risk of amputation. (centerwatch.com)
  • All the patients had comorbidity and 78.9% were Wagner's grade V. Ascending cellulitis and sepsis (68.4%) was the commonest indication for amputation. (scirp.org)
  • It was a retrospective audit of consecutive patients who were referred for and had amputation as a result of diabetic foot diseases in Sokoto, northwest Nigeria over a 2 year period from January 2016 to December 2017. (scirp.org)
  • Other parameters included presence or absence of Co-morbidity, duration of diabetics and indications for amputation. (scirp.org)
  • Ankle brachial index was also assessed while Doppler ultrasound was done in some patients and this was used to determine the nature of amputation to be done. (scirp.org)
  • Diabetic ketoacidosis was more prevalent among racial minorities with type 1 diabetes and COVID-19, researchers reported. (medpagetoday.com)
  • While only 13% of white patients with type 1 diabetes and COVID-19 presented with diabetic ketoacidosis, an alarming 33% of Hispanic and 55% of non-Hispanic Black patients did. (medpagetoday.com)
  • We used a diverse cohort of patients with type 1 diabetes and found there is a significantly increased risk of worse outcomes for Black and Hispanic patients with COVID-19 and diabetes. (medpagetoday.com)
  • Among the 180 patients with type 1 diabetes who tested positive, 34% where white, 24% were Black, and 20% were Hispanic. (medpagetoday.com)
  • Norwegian scientists with European partners have found evidence for the presence of Enterovirus in pancreatic islets of type 1 diabetic patients. (news-medical.net)
  • Minimal pancreatic tail resection was performed 3-9 weeks after onset of type 1 Diabetes in 6 adult patients (age 24-35 years). (news-medical.net)
  • VP1 was detected in the islets of all type 1 diabetes patients (2 of 9 controls). (news-medical.net)
  • The results provides evidence for the presence of enterovirus in pancreatic islets of type 1 diabetic patients, being consistent with the possibility that a low grade enteroviral infection in the pancreatic islets contribute to disease progression in humans. (news-medical.net)
  • Comparative therapeutic effects of orally administered 1,25-dihydroxyvitamin D(3) and 1alpha-hydroxyvitamin D(3) on type-1 diabetes in non-obese diabetic mice fed a normal-calcaemic diet. (medscape.org)
  • Cigolini M, Iagulli MP, Miconi V, Galiotto M, Lombardi S, Targher G. Serum 25-hydroxyvitamin D3 concentrations and prevalence of cardiovascular disease among type 2 diabetic patients. (medscape.org)
  • Serum 25-hydroxyvitamin D3 concentrations and carotid artery intima-media thickness among type 2 diabetic patients. (medscape.org)
  • In this research, we are going to consider the effect of discharge planning program on metabolic factors in type 2 diabetic patients. (magiran.com)
  • The samples consisted of 70 patients with type II diabetes, who were admitted to Vasei hospital in Sabzevar- Iran. (magiran.com)
  • These results implicate erythrocyte sialic acid in the erythrocyte rheology of hypertensive, obese, type 2 diabetic patients. (iospress.com)
  • Patient 1, a 51-year-old type 2 diabetic patient, was observed with a burn injury of the digits I-V of the right foot due to an unperceived thermal injury while working at a house construction site and wearing shoes. (medscimonit.com)
  • Patient 2, a 66-year-old type 2 diabetic patient, tried to treat a small dermal lesion caused by improper footwear by using a hot paraffin footbath, but during this unusual self-treatment a painless and unperceived burn injury developed. (medscimonit.com)
  • The pre-provider-visit appointment is just one type of encounter that Romero has with his patients. (migrantclinician.org)
  • This study aimed to assess the attitude and the popularity of using complementary and alternative medications and its perceived effect in diabetic control among Libyans adult who were diagnosed with type-2diabetes mellitus. (scialert.net)
  • Our aim was to evaluate EPC numbers in asymptomatic CVD type 1 diabetic patients with or without DN and to study the effect of CVD and medication on EPC numbers. (ku.dk)
  • Patients with type 2 diabetes mellitus are at increased risk of infections, with urinary tract being the most common site. (banglajol.info)
  • Effects of a Mediterranean-Style Diet on the Need for Antihyperglycemic Drug Therapy in Patients With Newly Diagnosed Type 2 Diabetes. (blogspot.com)
  • Idvall, M 2006, ' The xenotransplantation narratives of nine type 1 diabetic patients with renal failure ', Xenotransplantation , vol. 13, nr. 6, s. 509-511. (lu.se)
  • The condition may affect both type 1 and type 2 diabetic patients. (wikipedia.org)
  • Diabetic papillopathy is a self-limiting disease that may affect both type 1 and type 2 diabetic patients. (wikipedia.org)
  • We selected 30 patients with DN, diagnosed via renal biopsy at our hospital from March 2018 to November 2019, and enrolled 30 healthy individuals from a medical examination center as the control group. (nature.com)
  • We collected data from patients diagnosed with DN via renal biopsy at the Second Hospital of Jilin University from March 2018 to November 2019. (nature.com)
  • All patients were diagnosed in accordance with the classification standard of diabetes developed by the American Diabetes Association in 2018 [ 12 ]. (nature.com)
  • Thus, the pain literature includes limited information about the common meanings of living with diabetic peripheral neuropathic pain (DPNP) from the perspective of patients. (researchgate.net)
  • Wolf M, Thadhani R. Vitamin D in patients with renal failure. (medscape.org)
  • About 40% of patients who receive chemotherapy and nearly all patients who receive radiation develop oral mucositis, according to the Centers for Disease Control. (buffalo.edu)
  • A cross-sectional quantitative study was conducted among 192 adult diabetic patients, who are still under follow-up in two medical centers, Libya. (scialert.net)
  • A national committee for DM has existed since 1984 and all cases are registered and treated in diabetic centers and clinics free of charge including diagnostics facilities and medications 10 . (scialert.net)
  • The LA was significantly more prevalent in diabetic patients (P-value:0.001). (magiran.com)
  • Underlying this, Black and Hispanic patients had a significantly median HbA1c than white patients. (medpagetoday.com)
  • Technical and patient survivals did not differ significantly between groups ( P = 0.62, P = 0.34, respectively). (springer.com)
  • 0.002), measures of luminal and capillary size, respectively, were significantly reduced in all diabetic patients. (portlandpress.com)
  • Lower extremity edema significantly reduced in patients wearing the diabetic compression socks while the vascularity of the lower extremities was not affected. (sigvaris.com)
  • With diabetic compression socks, lower extremity edema was significantly reduced, while lower extremity vascularity remained unaffected. (sigvaris.com)
  • Conventional risk factors were significantly higher in patients with DN and they received more CVD-preventive treatment. (ku.dk)
  • Moreover, she noted that amputations are costly, in terms of the time patients have to spend in the hospital, the cost of hospital care, rehabilitation and prostheses, etc, and the postamputation care required. (medscape.com)
  • All patients who presented with diabetic ketoacidosis were admitted to the hospital. (medpagetoday.com)
  • A meta-analysis of 15 studies reported that hyperglycemia increased both in-hospital mortality and incidence of heart failure in patients admitted for acute myocardial infarction, independent of a previous diagnosis of DM, demonstrating that the presence of DM is not as important as the control of blood glucose concentrations. (medscape.com)
  • To determine the prevalence of dyslipidaemia and HT in paediatric diabetic patients seen at Tygerberg Hospital (TBH) and establish whether either is associated with body mass index (BMI), glycosylated haemoglobin (HbA1c) or duration of diabetes. (who.int)
  • The American Diabetes Association conservatively estimates that 12-25% of hospitalized adult patients have diabetes mellitus (DM). (medscape.com)
  • The current standard of care recommends revascularization after six weeks in patients with low-grade arterial disease of the lower extremities and nonhealing foot ulcer. (centerwatch.com)
  • Due to the sensory loss in the lower extremities, accidental foot injuries may develop in diabetic patients with distal sensorimotor polyneuropathy. (medscimonit.com)
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • A retrospective study of 154 diabetic patients, aged 1 - 19 years, seen at TBH between 2007 and 2017, was undertaken. (who.int)
  • To compare the differences of vitreous protein profiles in PDR patients before and after a complete anti-vascular endothelial growth factor (VEGF) loading dose with ranibizumab treatment. (frontiersin.org)
  • Twelve vitreous humor (VH) samples were collected from six PDR patients before (set as pre group) and after (set as post group) intravitreal injection of ranibizumab (IVR) treatment. (frontiersin.org)
  • While there have been no reports on the changes in vitreous humor (VH) protein profile before and after IVR treatment in the same patient. (frontiersin.org)
  • The most common adverse reactions (≥ 5%) reported in patients receiving aflibercept were conjunctival hemorrhage, eye pain, cataract, vitreous detachment, vitreous floaters, and increased intraocular pressure. (medscape.com)
  • For the analysis, the researchers performed a 12-month prospective observational assessment, via detailed review of case notes, of 250 patients with diabetes who had participated in the Concordance in Diabetic Foot Ulcer Infection (CODIFI) study and were still alive at the end of that, in May 2013. (medscape.com)
  • One limitation of this study was lack of data on the timing of diabetic ketoacidosis presentation relative to COVID-19 infection. (medpagetoday.com)
  • If the body is fighting an infection on the foot, unnoticed by the patient, a doctor can measure a temperature spike in the region of infection. (allaboutcircuits.com)
  • The team identified 1,411 patients with diabetes and HCV who were enrolled in the study, and received pegylated interferon plus ribavirin. (sciencedaily.com)
  • IMT is a non-invasive diagnostic and prognostic test in LA. The aim of this study was evaluate the carotid IMT and LA in diabetic patients as atherosclerosis surrogate marker. (magiran.com)
  • The case-control study was done on 100 diabetic patients and 100 controls. (magiran.com)
  • The purpose of this qualitative study was to elucidate the effects of DPNP on daily life and individual feelings regarding living with DPNP from the perspective of Turkish patients. (researchgate.net)
  • Conclusion: This study revealed that the majority of patients carry significant concerns about becoming a burden on their family and are afraid of becoming dependent on others because of DPNP. (researchgate.net)
  • The primary objective of this study was to evaluate the tolerability of capsules containing dextromethorphan (DM) and quinidine (Q) in patients with painful DPN. (nih.gov)
  • On study entry, patient-rated diabetic pain had to be moderate or greater. (nih.gov)
  • Three patients experienced 5 serious adverse events, only 1 of which was considered possibly related to study drug. (nih.gov)
  • The results of this open-label study indicated that the combination of DMIQ (dose range, DM30/Q30-DM120/Q120) was well tolerated in patients with pain associated with DPN. (nih.gov)
  • In one study, diabetic patients with onychomycosis had a 15% rate of secondary infections compared with a 6% rate of secondary infections in diabetic patients without onychomycosis. (diabetesjournals.org)
  • The results of the conducted study with two randomized groups show a positive effect of diabetic compression socks on lower extremity edema. (sigvaris.com)
  • The aim of this study was to assess whether diabetic socks with mild compression (18-25 mmHg) could reduce lower extremity edema in diabetic patients without negatively impacting vascularity ( 1 ). (sigvaris.com)
  • 38 patients with DCS and 39 patients with CON completed the study. (sigvaris.com)
  • This study demonstrates that mild-compression diabetic socks effectively reduce lower extremity edema in diabetic patients, without negatively impacting lower extremity vascularity. (sigvaris.com)
  • The aim of the study was to determine the risk factors and indications for amputations in diabetics and to correlate these risks with mortality in our environment. (scirp.org)
  • The purpose of this study was to determine the risk factors for amputations in patients with diabetic foot diseases and to correlate these risks with mortality. (scirp.org)
  • This study is designed to determine the causative organism of UTI in diabetic patient as well as their resistance pattern. (banglajol.info)
  • One hundred consecutive culture positive UTI in diabetic patient were enrolled in this study. (banglajol.info)
  • Diabetes mellitus patients attending the outpatients' clinic at Parirenyatwa Group of Hospitals between October 2013 and July 2014 were recruited into this analytical cross-sectional study. (ajol.info)
  • A total of 340 patients were enrolled into the study, of whom 73.2% were female. (ajol.info)
  • RESULTS -Findings replicated those of the initial PACIC validation study but with a much larger sample of diabetic patients and more Latinos. (diabetesjournals.org)
  • This study consisted of a series of cases with 22 diabetic patients of the Family Health Strategy (FHS), neighborhood of Dehon, city of Tubarão (SC). (bvsalud.org)
  • Suramin, the researchers discovered, is effective for wound healing and well-equipped to meet the needs of diabetic and cancer patient populations. (buffalo.edu)
  • Patients with rubeosis (Grades III and IV) on IFA had a 63% incidence of postoperative neovascular glaucoma, thus isolating them as a high risk group. (unboundmedicine.com)
  • The visual outcome of patients developing neovascular glaucoma was poor. (unboundmedicine.com)
  • Acute coronary syndrome -- an umbrella term the American Heart Association uses to define diseases, such as heart attack or angina, where blood to the heart is blocked -- occurred in 4.1%, 6.6% and 7.4% of treated, untreated and uninfected patients. (sciencedaily.com)
  • Like with so many diseases, NPs help patients focus intensely on prevention efforts and ways to take better control of their daily health," she says. (minoritynurse.com)
  • Diabetic foot diseases are responsible for more hospitalizations than any other complication of diabetes. (scirp.org)
  • In a paper published in 1825, this pharmacist stated that physicians and other persons attending patients with contagious diseases would benefit from moistening their hands with a liquid chloride solution ( 2 ). (cdc.gov)
  • 1 See paragraphs 16-18 of document A69/10, based on data included in the Noncommunicable diseases progress monitor 2015, availab le at http://www.who.int/nmh/publications/ncd-progress-monitor-2015/en/ (accessed 10 October 2016). (who.int)
  • 13 , 15 Some diabetic patients can be obese, which may make the act of bending over to examine their feet difficult. (diabetesjournals.org)
  • Background: The healing of foot wounds in patients with diabetes mellitus is frequently complicated by critical limb threatening ischemia (neuro-ischemic diabetic foot syndrome, DFS). (mdpi.com)
  • Background: In approximately 80% of diabetes-related lower extremity amputations, patients suffer from a foot ulcer, often caused by lower extremity arterial disease. (centerwatch.com)
  • Diabetic patients suffering from decreased foot sensation are more prone to trauma, which damages the nail and nail matrix, opening portals of entry for the fungus to infect the nail. (diabetesjournals.org)
  • Additionally, diabetic patients with onychomycosis had an approximately three times greater risk of gangrene or foot ulcer compared with diabetic patients without it. (diabetesjournals.org)
  • The diabetic foot is prone to neuroarthropathy, ulceration, infections (Cellulitis, deep skin and soft tissue infections, acute and chronic Osteomyelitis), and Gangrene. (scirp.org)
  • Effects of pedicled flap combined with membrane induction technique in repairing foot and ankle wounds in diabetic patients]. (bvsalud.org)
  • To explore the effects of pedicled flap combined with membrane induction technique in repairing foot and ankle wounds in diabetic patients . (bvsalud.org)
  • NPs have a daily responsibility to understand the risk factors and work with patients to mitigate those risks before they become diabetic. (minoritynurse.com)
  • The use of linagliptin as monotherapy or in combination with metformin, sulfonylureas, or pioglitazone led to improvement in glycemic control and was well tolerated by most patients. (dovepress.com)
  • 4 , 10 - 22 The outcome from not treating onychomycosis in diabetic patients can be worse than in those without diabetes. (diabetesjournals.org)
  • This One-Pager reviews the effects of mild-compression diabetic socks on lower extremity edema in patients with diabetes. (sigvaris.com)
  • To this end, 80 patients with diabetes and LE edema were randomized to receive either mild-compression knee-high diabetic socks („DCS") or non-compression knee-high diabetic socks („CON") . (sigvaris.com)
  • Wearing mild-compression knee-high diabetic socks may be effective and safe in reducing lower limb edema in patients with diabetes. (sigvaris.com)
  • As NPs, we discuss things like obesity, poor eating, and bad exercise habits as risk factors that drastically increase patients' chances of becoming pre-diabetic or diabetic. (minoritynurse.com)
  • Patients in the Mediterranean diet group also experienced greater weight loss and an improvement in some coronary risk factors. (blogspot.com)
  • Within that department, OCH offers Salud ("Health"), an in-clinic diabetes care management program in which patients work with CHWs, and Pasos Hacia Salud ("Steps Toward Health"), a community-based diabetes education program that is open to the public. (migrantclinician.org)
  • We evaluated relationships between survey scores and patient characteristics, quality of diabetes care, and self-management. (diabetesjournals.org)
  • Based on the preliminary efficacy results, a randomized, controlled, double-blind trial is warranted to assess the tolerability and efficacy of this combination in patients with DPN. (nih.gov)
  • 4 Many studies have been undertaken to assess whether diabetic individuals suffer from a higher incidence of onychomycosis than those without diabetes, 4 - 10 and most have concluded that they do. (diabetesjournals.org)
  • However, there are few instruments to assess the level of CCM-congruent activities that patients receive. (diabetesjournals.org)
  • Diabetic patients see the pancreatic islet transplantation (IT) as an idealized form of cure of the disease, and put great expectations in this treatment. (bvsalud.org)
  • To investigate the presence of xerostomia in patients with diabetes. (bvsalud.org)
  • Ten patients that presented the following characteristics were qualified: mood stability, family support, realistic judgment of the possible results of the treatment, adherence behavior and presence of coping strategies. (bvsalud.org)
  • Currently accepted criteria for diagnosis of diabetic papillopathy include: Presence of diabetes mellitus (Appr. (wikipedia.org)