Loading...
  • glucose in the b
  • Often it is a sign of diabetes, which is very dangerous for its many complications.His late diagnosis leads to a constant increase in the level of hyperglycemia and the toxic effects of high concentrations of glucose in the blood vessels, nerves. (vitamedd.com)
  • Quite often diagnosed hyperglycemia and infectious diseases.Here, the role played by at least two factors.Needless effects of an infectious agent may affect glucose levels.On the other hand, the disease is any such organism to stress, which should be the standard cascade of reactions starting with the ejection mechanism of glucose in the blood. (vitamedd.com)
  • vascular
  • We will then test the hypothesis that enhanced vascular inflammation augments monocyte recruitment in peripheral arteries, and that hyperglycemia raises intracellular free cholesterol levels, thereby promoting the unfolded protein response and premature apoptosis of macrophage foam cells. (grantome.com)
  • Thus, in Aim 2, we will test the hypothesis that hyperglycemia impairs transcriptional reprogramming of vascular cells and thereby the removal of arterial lipid, the egress of macrophages and the accumulation of collagen in response to lipid lowering. (grantome.com)
  • Hyperglycemia is a prime cause of vascular complications, including kidney disease. (oncologynurseadvisor.com)
  • We hypothesized that ER stress pathways interact with inflammatory signaling leading to retinal barrier dysfunction in diabetic retinopathy (DR). Using a well characterized chronic proinflammatory tie2-TNF mouse model and retinal endothelial cells we assessed the connection between ER stress and hyperglycemic stress in mediating vascular permeability. (arvojournals.org)
  • Tie2-TNF and age matched wildtype mice were made diabetic with intraperitoneal injections of Streptozotocin and evaluated for retinal vascular permeability by fluorescein labeled-BSA leakage assay. (arvojournals.org)
  • mice
  • Unfortunately, studies of existing mouse models of atherosclerosis were often marred by the recently recognized effect by which hyperglycemia increases plasma cholesterol levels in diabetic mice. (grantome.com)
  • Studies in which hyperglycemia was found to accelerate atherosclerosis also reported increased plasma cholesterol in diabetic mice. (grantome.com)
  • When fed a low-fat chow diet, these mice, while moderately dyslipidemic, are resistant to further hyperglycemia-induced hypercholesterolemia. (grantome.com)
  • Diabetic mice had loss of NADPH diaphorase-stained myenteric neurons, delayed gastric emptying, and increased intestinal transit time. (nih.gov)
  • The pathophysiological effects of hyperglycemia (apoptosis, reduced Akt phosphorylation, loss of inhibitory neurons, motility changes) were reversed in diabetic glial fibrillary acidic protein-GDNF (GFAP-GDNF) Tg mice. (nih.gov)
  • This study aimed to investigate the role of ATPSβ in regulation of hepatic ATP content and glucose metabolism in diabetic mice. (diabetesjournals.org)
  • ATPSβ expression and ATP content were both reduced in the livers of type 1 and type 2 diabetic mice. (diabetesjournals.org)
  • Hepatic overexpression of ATPSβ elevated cellular ATP content and ameliorated hyperglycemia of streptozocin-induced diabetic mice and db / db mice. (diabetesjournals.org)
  • In this study, we report that ATPSβ expression is reduced and correlated with ATP content in the livers of type 1 and type 2 diabetic mice. (diabetesjournals.org)
  • Next, about 3 × 10 6 differentiated cells were transplanted into the renal sub-capsular space of streptozotocin (STZ)-induced diabetic nude mice. (drcalapai.net)
  • Transplantation of functional IPCs into the renal subcapsular space of STZ-induced diabetic nude mice ameliorated the hyperglycemia. (drcalapai.net)
  • Interestingly, whole mount retinal preparation from diabetic tie2-TNF mice demonstrated hyper permeable vessels with strong extravasation of FITC-BSA and extravasation of red blood cells. (arvojournals.org)
  • patients
  • Yamamoto M, Yamaguchi T, Yamaguchi M, Kaji H, Sugimoto T (2009) Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications. (springermedizin.de)
  • 160 non-diabetic ASA I or II patients, aged between 18-65 years were selected for the trial. (docphin.com)
  • metabolism
  • As a lipophile I have long wondered whether, outside of the neurons, palmitic acid might be a reasonable substitute for ketones in rescuing muscle metabolism damaged by hyperglycaemia. (blogspot.com)
  • hepatic
  • Given the crucial role of ATPSβ in controlling mitochondrial ATP synthesis ( 4 , 5 ), we hypothesized that its expression in the liver may be deregulated and associated with increased hepatic glucose production under diabetic conditions. (diabetesjournals.org)
  • lack
  • Moreover, the lack of suitable mouse models of atherosclerosis regression have hampered studies designed to address the effects of diabetic hyperglycemia on atherosclerosis regression, a promising clinical treatment strategy for cardiovascular disease. (grantome.com)
  • peripheral
  • 2002) UKPDS 59: Hyperglycaemia and other potentially modifiable risk factors for peripheral arterial disease in type 2 diabetes. (diabetesaid.com)
  • 2001). Hyperglycaemia is well recognised to be an important pathogenic factor in the development of peripheral neuropathy , and several studies have shown that peripheral neuropathy, defined as the absence of Achilles tendon reflexes and impaired vibration sense in the great toe, is an independent predictor of amputation even after adjustment for age, sex and duration of diabetes (Nelson etal. (diabetesaid.com)
  • survival
  • We examined the effects of hyperglycemia on enteric neuronal survival and the effects of glial cell line-derived neurotrophic factor (GDNF) on modulating this survival. (nih.gov)
  • causes
  • specialist will determine if hyperglycemia is a symptom of diabetes or associated with other causes.Perhaps he will recommend to purchase a portable blood glucose meter for self-monitoring of blood sugar throughout the day.Current models give a fairly accurate reading, the error is comparable to laboratory analyzes. (vitamedd.com)
  • study
  • This follow-up study showed risk reduction of diabetic nephropathy persists long-term, even after glycemic control equalized between the two groups, with a mean A1c of 8% for both groups for several years after the DCCT. (oncologynurseadvisor.com)
  • The study aimed to determine the prevalence of hyperglycemia in sick children admitted into the emergency rooms and to investigate its relationship with adverse outcomes. (ovid.com)
  • Balanced hydroxyethyl starch solution and hyperglycaemia in non diabetics - a prospective, randomized and controlled study. (docphin.com)
  • Nath SS, Pawar ST, Ansari F, Debashis R. Balanced hydroxyethyl starch solution and hyperglycaemia in non diabetics - a prospective, randomized and controlled study. (docphin.com)
  • health
  • If it's not treated, hyperglycemia can cause serious health problems. (kidshealth.org)
  • In addition to regular doctor's visits and testing - particularly for a youth who may not be accustomed to the discipline necessary - a diabetic may have a health care team assigned to help administer their unique program. (bestdrugrehabilitation.com)
  • possible
  • Publishing their results in the Archives of Internal Medicine, representatives from the Institute for Clinical Evaluative Sciences and the Women's College Research Institute at Women's College Hospital from Toronto, Canada, it was said that hyperglycaemia was very possible in such individuals. (barchester.com)