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  • polycystic ovary sy
  • The objective of this study was to evaluate and compare the clinical, biochemical, hormonal and gynecological aspects of polycystic ovary syndrome at a hospital in South India. (ijpsonline.com)
  • The observational, case-controlled study was conducted from April 2011 to January 2014 and recruited 192 polycystic ovary syndrome patients and 205 normal women. (ijpsonline.com)
  • About 16% of polycystic ovary syndrome women were obese and 91% reported to have an increased waist/hip ratio. (ijpsonline.com)
  • Oligomenorrhea was observed in 74% women with polycystic ovary syndrome. (ijpsonline.com)
  • The tested variables revealed that body mass index, waist/hip ratio, hirsutism, testosterone, insulin, ovarian volume and follicular count were elevated in polycystic ovary syndrome patients compared to the control subjects. (ijpsonline.com)
  • Increased testosterone levels correlated positively with luteinizing hormone/follicle-stimulating hormone ratio (p=0.023), hirsutism (p=0.001) and antral follicular count (p=0.004) in polycystic ovary syndrome patients in the studied population. (ijpsonline.com)
  • Increased testosterone levels, ovarian volume and antral follicular count or combination of these have been considered to be risk factors in developing polycystic ovary syndrome patients. (ijpsonline.com)
  • Polycystic ovary syndrome (PCOS) is the most common and highly complex endocrinopathy, which has obtained a great deal of importance in recent years owing to it being the most prevalent cause of anovulatory infertility. (ijpsonline.com)
  • Identification of the metabolic fingerprints in women with polycystic ovary syndrome using the multiplatform metabolomics technique. (nih.gov)
  • risk factors
  • Acai-rich smoothies may reduce cholesterol levels and improve metabolic syndrome risk factors in overweight subjects, suggest preliminary findings from a pilot study. (nutraingredients-usa.com)
  • One month later, the researchers analyzed risk factors of metabolic syndrome, including cholesterol levels, insulin and glucose levels, and blood levels of C-reactive protein (CRP), a marker for inflammation. (nutraingredients-usa.com)
  • Of these, the 2001 Third Report of the NCEP's Adult Treatment Panel has emerged as the most widely used definition, primarily because it provides a relatively simple approach for diagnosing the metabolic syndrome by employing easily measurable risk factors ( 3,6 ). (onlinejacc.org)
  • These data emphasize that metabolic dysregulations are the leading risk factors for occlusive vascular events and early death in patients with severe psoriasis. (clinicaltrials.gov)
  • Receiver operating characteristic curve analysis suggested that yielding at least 80% sensitivity, the WC value of 90 cm in both genders was more appropriate in predicting the presence of two or more metabolic syndrome risk factors in this population. (umd.edu)
  • A control group of 30 subjects had less than two risk factors for metabolic syndrome, with normal glucose and triglyceride levels. (ucdavis.edu)
  • incidence
  • Based on medical records and glucose tolerance test (OGTT), the cumulative incidence of diabetes was analyzed in this five-year study by Cox regression models. (biomedcentral.com)
  • Obesity is a heterogeneous disorder related to environmental and genetic factors, whose incidence has dramatically increased. (springer.com)
  • T2DM
  • Many people do not manifest typical signs or symptoms commonly associated with T2DM and therefore, if feasible, all persons over the age of 25 years should undergo an annual test to rule out the presence of diabetes. (diabetesindia.com)
  • cholesterol
  • Such individuals often are offspring of type 2 diabetic parents, themselves developing type 2 diabetes at relatively young ages, having history of myocardial infarction and of cholesterol cholelithiasis. (diabetesjournals.org)
  • Objectives We sought to conduct a systematic review and meta-analysis of the cardiovascular risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol Education Program (NCEP) and 2004 revised National Cholesterol Education Program (rNCEP) definitions. (onlinejacc.org)
  • Ever since the metabolic syndrome was described by Reaven in 1988 ( 2 ), a number of definitions have been published by organizations including the National Cholesterol Education Program (NCEP) ( 3 ), the International Diabetes Federation ( 4 ), and the World Health Organization ( 5 ), among others. (onlinejacc.org)
  • Few studies have examined the association between alcohol consumption and the metabolic syndrome as defined by the National Cholesterol Education Program ( 11 - 13 ), and data are limited on how the relation may be modified by type of alcohol, sex, or race/ethnicity ( 14 , 15 ). (diabetesjournals.org)
  • Hyperglycemia
  • The diagnosis of diabetes made by a using a meter should always be confirmed by repeat testing on another day, preferably in a laboratory, unless there is unequivocal hyperglycemia or obvious symptoms. (diabetesindia.com)
  • hepatic
  • NAFLD may be considered an additional feature of the metabolic syndrome, with specific hepatic insulin resistance. (diabetesjournals.org)
  • The investigators propose that these alterations in lipid kinetics account for the phenotypic changes characteristic of this syndrome: increased lipolysis would facilitate peripheral lipoatrophy, increased intra-adipocyte re-esterification (if selective in intrabdominal depots) would contribute to the central obesity, and increased hepatic re-esterification together with impaired VLDL- and chylomicron-TG clearance would lead to hypertriglyceridemia. (clinicaltrials.gov)
  • Inflammation
  • "To our knowledge, this is the first study investigating the effects of decaffeinated green tea supplementation on biomarkers of inflammation and features of metabolic syndrome in obese population in the US," ​ wrote the researchers. (nutraingredients.com)
  • The UC Davis study found that fat stored in the buttock area - also known as gluteal adipose tissue - secretes abnormal levels of chemerin and omentin-1, proteins that can lead to inflammation and a prediabetic condition know as insulin resistance in individuals with early metabolic syndrome. (ucdavis.edu)
  • As it's also an indicator of inflammation and insulin resistance, it could also emerge as part of a biomarker panel to define high-risk obesity states. (ucdavis.edu)
  • Diagnosis
  • Due to the polysymptomatic nature of this syndrome and lack of consensus on its diagnostic criteria there is a strong need of finding a reliable biochemical or molecular marker, which would facilitate making the accurate diagnosis of PCOS. (nih.gov)
  • Currently, no specific WC thresholds for diagnosis of central obesity in Hispanics are available. (umd.edu)
  • testosterone levels
  • The relationship between obesity and low testosterone levels in men is complex and apparently bidirectional. (springer.com)
  • By contrast, obesity predicts low total and free testosterone levels. (springer.com)
  • Several epidemiological studies have established an inverse correlation between obesity and serum total and free testosterone levels in men of all ages [ 3 , 4 , 5 , 6 ], however, although many underlying pathophysiological mechanisms have been proposed, many more need to be elucidated. (springer.com)
  • The relationship between obesity and low testosterone levels appears to be complex and multifactorial. (springer.com)
  • Although it is reported that obesity is associated with profound alterations in testosterone production rate and metabolic clearance, it is also true that, by contrast, low testosterone levels in primary or secondary hypogonadic states may in turn lead to increase visceral adiposity and insulin resistance. (springer.com)
  • This review will focus on the recent findings on the relationship between testosterone levels and obesity. (springer.com)
  • Thus
  • Besides that, according to the National Health and Morbidity Surveys (2011), 15.1% of Malaysians aged 18 and above were obese thus Malaysia has the highest rate of obesity in south east Asia and the 6th in Asia. (hindawi.com)