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  • mouse embryonic
  • Time-lapse microscopy is being performed on cultured mouse embryonic kidney explants overexpressing green fluorescent protein-tagged components of the Wnt and FGF signaling pathways. (nsf.gov)
  • A mammalian protein similar in structure to the active component of honeybee royal jelly - the queen-making goop that helps worker bees raise a new egg-laying diva for the hive - functions as kind of a fountain of youth for mouse embryonic stem cells, according to researchers at the Stanford University School of Medicine . (stanford.edu)
  • They applied royalactin to mouse embryonic stem cells to study the cells' response. (stanford.edu)
  • gene-expression
  • One can attempt to isolate mRNA from every tissue at different developmental stages, measure gene expression, and assign expression indexes to every tissue at every time for every gene, in order to recreate the entire developmental expression pattern. (biomedcentral.com)
  • Based on publicly available gene expression profiling data, one unique pattern for cancer embryonic stem cell-like attractors was identified alongside deficiency of Mi-2/NuRD and its partner's chromatin remodel systems (CRS) critical for germline-reactivated cancers, and particularly extendable to deficiency of regulatory components of cell-cycle and cell-division. (omicsonline.org)
  • Moreover, our results of Gene Expression Dynamics Inspector (GEDI) assays exemplified with the state of cell attractors of fruitfly l(3)mbt brain tumor reveals that cancer embryonic stem cell-like attractors might fall in between those of two-cell embryos and onset of differentiation states. (omicsonline.org)
  • protein
  • Bringing together the facts that (1) the ix phenotype is female-specific and (2) functions at the end of the sex determination hierarchy, yet (3) is expressed sex non-specifically and appears likely to encode a transcription factor with no known DNA-binding domain, leads to the inference that ix may require the female-specific protein product of the doublesex ( dsx ) gene in order to function. (biologists.org)
  • A modern description of a gene must consider not only its structure, as a length of DNA, but also its function, as a unit of heredity in transmission from one generation to the next and in development as a carrier of coded information of the sequence of a protein or RNA molecule. (encyclopedia.com)
  • Kevin Wang holds a flask of cells that have been engineered to produce the Regina protein, a mammalian protein similar in structure to the active component of honeybee royal jelly. (stanford.edu)
  • describe
  • Conversely, when taxa are the component parts themselves, the nested hierarchies describe a different kind of timetree that explores the chronology of component innovation of the organismal system. (frontiersin.org)
  • forebrain
  • Thus, the highest level divisions of the Developmental CNS Model are the Telencephalon, Mesencephalon, and Rhombencephalon, which correspond to a large extent, but with significant exceptions, to the forebrain , midbrain , and hindbrain of the Classical Model. (washington.edu)
  • proteins
  • After the embryonic segments have formed, the Hox proteins determine the type of appendages (e.g. legs, antennae, and wings in fruit flies) or the different types of vertebrae (in humans) that will form on a segment. (hitchhikersgui.de)
  • neuroscience
  • The Functional Model is most useful for addressing the fundamental challenge of neuroscience, namely to understand the relations between neural structure and function. (washington.edu)
  • changes
  • It is well established that post-menopausal women are at increased risk for developing osteoporosis, but could that be related to subtle pre-menopausal changes in bone structure? (news-medical.net)
  • We aim to examine the potential relation of changes in developmental timing (heterochrony) to the origin of limb morphological diversity in an explicit comparative and quantitative framework. (biomedcentral.com)
  • Term
  • The number of paths to term (in this case, one) indicates how many paths through the DAG structure can be traversed to reach the term. (nih.gov)
  • The number of genotypes and annotations following the term 'lethality-embryonic/perinatal' is a hypertext link to those data. (nih.gov)
  • novel
  • Finally such features may contribute to a better understanding of carcinogenesis under cancer embryonic stem celllike attractors theory and provide novel angles for cancer therapeutic interventions. (omicsonline.org)
  • diversity
  • Tetrapods exhibit great diversity in limb structures among species and also between forelimbs and hindlimbs within species, diversity which frequently correlates with locomotor modes and life history. (biomedcentral.com)
  • data
  • Davidson and Baldock announced the project in an article titled "A Real Mouse for Your Computer," citing the need to manage and analyze the volume of data that overwhelmed developmental biologists. (asu.edu)
  • find
  • Consistent with this inference, we find that for all sexually dimorphic cuticular structures examined, ix and dsx are dependent on each other to promote female differentiation. (biologists.org)
  • The Classical Model is reflected in the hierarchy of human and macaque brain structures that you find when you click 'Locus in Brain Hierarchy' below. (washington.edu)