Developmental functional laterality. Medical search. Frequent questions

We used functional transcranial Doppler ultrasound (fTCD) to assess cerebral blood flow during language production in 57 four-year-olds, including 15 children who had been late-talkers when first seen at 20 months of age. (peerj.com)
Measurement of language laterality using functional transcranial Doppler ultrasound: a comparison of different tasks. (ox.ac.uk)
Her DPhil work in the Faculty of Primary Education of the National & Kapodistrian University of Athens (NKUA) focuses on the differences in language laterality among children with intellectual disability, typical developement and intellectual giftedness using behavioural and neuropsychological indices, as well as a brain imaging technique, functional transcranial Doppler ultrasound (fTCD). (frederick.ac.cy)

Thus, compared to non-autistic individuals, they show subtle changes in the asymmetry of the brain structure and a lower laterality of functional activation, in terms of the use of the left or right hemisphere in the brain. (mpg.de)
Researchers locate one cause in altered patterns of brain asymmetry, possibly related to atypical lateralisation of functional processes. (mpg.de)
Asymmetry is a key feature of brain organisation, supporting flexible interplay between local neuronal modules linked to the functional specialisation that underlies human cognition,' explains Bin Wan, lead author of the study. (mpg.de)
When segregating unimodal and transmodal systems, reduced left-directed functional asymmetry of language network organisation was observed in individuals with autism compared to non-autistic individuals. (mpg.de)
The researchers found that there are large differences in the asymmetry of functional organization in autistic and non-autistic individuals. (mpg.de)
Sofie Valk, head of the Cognitive Neurogenetics research group at MPI CBS, classifies: 'Taken together, our work shows that there are subtle differences in the asymmetry of functional organisation in autistic and non-autistic individuals. (mpg.de)

An apparent paradox in the field of neuropsychology is that people with atypical cerebral lateralization do not appear to suffer any cognitive disadvantage, yet atypical cerebral lateralization is more common in children and adults with developmental language disorders. (peerj.com)
We categorized cerebral lateralization as left, right or bilateral, and compared proportions with each type of laterality with those seen in a previously tested sample of children aged 6-16 years. (peerj.com)
Even when is diferent on every children, our recommendation is attach to the development of "laterality in children" as we exercise right-left and they have to be able to understand the instructions, there are studies supporting the thesis of a functional lateralization in complex coordinative tasks and in maximal strength during developmental ages at 6-11 years old. (capoeiras.com)
2005a ), as well as the functional lateralization of the two hemispheres (Gotts et al. (springer.com)

This longitudinal developmental calcium FC dataset provides an essential resource for further algorithm development and studies of healthy development and neurodevelopmental disorders. (biorxiv.org)
This is particularly controversial in childhood, where aspects of cognition, such as working memory, are closely related to school success and are implicated in numerous developmental disorders. (ox.ac.uk)
Research has consistently shown significant prefrontal activation during tasks in typically developed children, but this activation may be abnormal in children with developmental disorders. (frontiersin.org)
Interestingly, many neurodevelopmental and psychiatric disorders have been associated with altered functional hemispheric asymmetries. (johnshopkins.edu)
It may allow us to identify new kinds of language disorders and will clarify the relationships between language impairment and other developmental disorders. (brookes.ac.uk)
Studies show that developmental language disorders run in families - a brother or sister of someone who has already been diagnosed will have an increased risk of developing the disorder themselves. (brookes.ac.uk)
developmental language disorders are genetic and is therefore caused (at least in part) by the genes passed on from parents to children. (brookes.ac.uk)
Her research interests focus on Special education and especially on children with Developmental Disorders (Intellectual Disability, Autism Spectrum Disorder), Gifted children, Early Intervention and Educational Neuroscience. (frederick.ac.cy)

Comparative research contributions continue to strengthen the position that ancient functional and anatomical brain biases are preserved in modern humans. (bbk.ac.uk)

Bin Wan and Sofie Valk from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and Forschungszentrum Jülich (Germany), together with international researchers from South Korea, UK, Switzerland, and Canada, have now investigated in a study whether such functional asymmetries in autism are indicative of altered systematic organisation in the brain in general. (mpg.de)
Laterality: Asymmetries of Body, Brain and Cognition 26 (3), pp. 330-335. (bbk.ac.uk)

Part of your child's vision development includes the concepts of laterality and directionality. (thevisiontherapycenter.com)
Through a functional vision test , however, they can diagnose vision problems that affect the development of laterality and directionality and create symptoms like word reversal. (thevisiontherapycenter.com)

Journal of Developmental Biology (2023) 11 (1): 9. (biologists.com)
Developmental Biology (2023) 496: 36. (biologists.com)

This may suggest that the atypical functional laterality in autism results from altered developmental trajectories. (mpg.de)
However, developmental trajectories of neural circuitry subserving emotion regulation and the role that they may play in illness onset have not yet been examined in patients at risk for psychosis. (nih.gov)
Longitudinal data are needed to confirm aberrant developmental trajectories intra-individually and to examine whether these abnormalities are predictive of conversion to psychosis, and of later deficits in socioemotional functioning. (nih.gov)

However, how they unfold over developmental time and contribute to cognitive abilities is still unclear. (bbk.ac.uk)
Individual learning performance of cognitive function is related to functional connections within 'task-activated' regions where activities increase during the corresponding cognitive tasks. (nature.com)
Her Audiology research incorporates elements of Developmental psychology, Cognitive psychology and Brain mapping. (research.com)

However, the emergence of functional connectivity (FC) in development has not been fully characterized, and hemodynamic-based measures are vulnerable to any neurovascular coupling changes occurring in parallel. (biorxiv.org)
Functional connectivity (FC) imaging is a minimally invasive technique by which circuit and network function can be observed in vivo in the human and animal brain. (biorxiv.org)
While structural connectivity characterizes intra- and interregional physical connections, FC investigates the functional relationship between neural activity in different brain regions, and has been used extensively in clinical populations as well as in animal models to probe healthy function and disease-related dysfunction. (biorxiv.org)
We measured cortical atrophy as well as disruption in resting-state functional connectivity (rsFC) and then investigated longitudinal brain changes in a subset of CJD patients. (bvsalud.org)
The present study employed a cross-sectional analysis to examine age-related functional activation in amygdala and prefrontal cortex, as well as functional connectivity between these regions, in adolescents at clinical high risk (CHR) for psychosis relative to typically developing adolescents. (nih.gov)
Moreover, a psychophysiological interaction analysis revealed decreased amygdala-prefrontal functional connectivity among CHR adolescents, consistent with disrupted brain connectivity as a vulnerability factor in schizophrenia. (nih.gov)
These results suggest that the at-risk syndrome is marked by abnormal development and functional connectivity of neural systems subserving emotion regulation. (nih.gov)
We calculated functional connectivity patterns of whole-brain intrinsic networks and examined whether a sparse linear regression model predicts a performance plateau from the individual patterns. (nature.com)
To test our hypothesis, we calculated functional connectivity patterns among whole-brain networks in resting-state functional magnetic resonance imaging (fMRI) and examined whether the patterns predict individual learning performance in a short period of training (80-90 min). (nature.com)
An element of great interest in functional connectivity is 'homotopic connectivity' (HC), namely the connectivity between two mirrored areas of the two hemispheres, mainly mediated by the fibers of the corpus callosum. (springer.com)
HC refers to the (structural or functional) connectivity between two homologous areas of the two hemispheres, mainly mediated by the fibers of the corpus callosum (Goldstein et al. (springer.com)
Is resting-state functional connectivity altered in regular cannabis users? (edu.au)

Development: For advances in developmental biology and stem cells. (lu.se)

We therefore used optical fluorescence imaging to trace longitudinal calcium FC in the awake, resting-state mouse cortex in the same mice at 5 developmental time points beginning at postnatal day 15 (P15) and ending in early adulthood (P60), resulting in over 500 imaging epochs with both calcium and hemodynamics available as a resource for the field. (biorxiv.org)
Proof-of-principle analyses revealed that calcium FC displayed coherent functional maps as early as P15, and FC significantly varied in connections between many regions across development, with the developmental trajectory's shape specific to the functional region. (biorxiv.org)

The comparison list generation task was not systematically lateralised, but nevertheless laterality indices (LIs) from this task were significantly correlated with the other two tasks. (ox.ac.uk)

Therefore, we hypothesized that learning performance is determined by functional connections among intrinsic networks that include both task-activated and less-activated networks. (nature.com)
My collaborators and I believe that our studies are providing insight into the nature of normal brain development and the consequences of disrupting the partnership between intrinsic developmental mechanisms and early sensorimotor experience. (duke.edu)

Alternating hemiplegia of childhood (AHC) is a distinct clinical disorder characterized by recurrent episodes of hemiplegia, abnormal ocular movement, and progressive developmental delay. (malvernlegacyproject.org)
[ 5 , 6 ] a patient's splenic phenotype should be viewed as merely one phenotypic aspect of an underlying laterality disorder, even though many prior reviews of heterotaxy syndrome have divided patients into 2 groups based on only splenic phenotype. (medscape.com)

CONCLUSIONS: CJD shows unique anatomical and functional disruptions in the cerebral cortex, distinct from AD. (bvsalud.org)
My primary interest is to understand how sensorimotor experience in early life influences - for better or worse - the formation and maturation of functional neural circuits in the cerebral cortex. (duke.edu)

Clinical Physiology and Functional Imaging. (lu.se)
Despite the importance of the developmental pathways followed by these small groups of progenitor cells and their impact on the physiology of the organism, we still know little about the set of developmental strategies that progenitor cells deploy in vivo to overcome the challenges imposed by the environment as they travel to the site of terminal differentiation. (elifesciences.org)

More generally, laterality preference is associated with one's success in sports. (capoeiras.com)

Her study in Neuroplasticity, Functional magnetic resonance imaging and Serial reaction time is done as part of Neuroscience. (research.com)

While FC imaging is a powerful tool that provides insight into how the brain functions under a wide variety of conditions, the development of the functional connectome between birth and adulthood is not well-characterized. (biorxiv.org)
Skeletal class II and III anomalies are a developmental condition, in most cases, not due to pathological processes, but to a moderate distortion of normal development, this causes alteration of the aesthetic that influences the levels of self-esteem of the patients. (sld.cu)
It therefore facilitated stable development of laterality in most cases also when presomite stages were taken into culture. (studylibde.com)
Here, we examine this question during the early stages of morphogenesis of the embryonic laterality organ, the first organ to form during vertebrate development, using the zebrafish as a model organism. (elifesciences.org)

2017 ). The presence of functional HC has been also confirmed by numerous meta-analytic studies based on neuroimaging data and by applying different methods (Laird et al. (springer.com)

Background: Relative blood flow in the two middle cerebral arteries can be measured using functional transcranial Doppler sonography (fTCD) to give an index of lateralisation as participants perform a specific task. (ox.ac.uk)
Language laterality has mostly been studied with fTCD using a word generation task, but it is not clear whether this is optimal. (ox.ac.uk)

We applied an individual-based approach to characterize the functional brain organization of 10 patients with CJD, 8 matched patients with AD, and 8 normal controls. (bvsalud.org)
An important contributing factor is the difficulty of probing the functional organization of children's brains between 1 and 3-4 years of age, when language makes the biggest developmental leap (e.g. (biorxiv.org)
Topographic mapping of neural circuits is fundamental in shaping the structural and functional organization of brain regions. (mdpi.com)

Developmental studies have reported behavioral evidence showing that EF changes significantly during preschool years. (frontiersin.org)

These differences may be developmental and vary greatly from person to person. (mpg.de)
Throughout the article reference is made to individual differences and developmental changes associated with interhemispheric interaction. (virginia.edu)

This articles looks at developmental ages and stages to encourage tooth brushing for babies, toddlers, preschoolers and school-age children. (yourkidsot.com)

Donati, G. and Forrester, Gillian (2021) Hindsight 20/20: the future of laterality research. (bbk.ac.uk)

Using a combination of genetic and live imaging approaches, we are aiming to dissect the functional links between neuro-epithelial polarity and Delta/Notch signalling. (unice.fr)

This suggests that word and sentence generation involve adding a constant directional bias to an underlying continuum of laterality that is reliable in individuals but not biased in either direction. (ox.ac.uk)
Visual electrodes responded to both contralateral and ipsilateral sounds with a contralateral bias, suggesting that previously observed laterality effects do not emerge from a distinct neural generator but rather reflect laterality-biased responses in the same neural populations that produce phase-resetting responses. (mit.edu)

As expected in cases of early left hemisphere (LH) damage, we find that EG has a fully functional language network in her right hemisphere (RH) and performs within the normal range on standardized language assessments. (biorxiv.org)

Cellular membranes are essential for the functional compartmentalization of the organism. (unice.fr)

In future research we suggest that consistency of laterality across tasks might have more functional significance than strength or direction of laterality on any one task. (ox.ac.uk)

Our work suggests that another important function of the ESCRT machinery is to promote the virus-like cell surface budding of extracellular vesicles that ensure the transport of developmental signaling molecules such as the major developmental morphogen Hedgehog (Matusek et al, 2014, Juan and Fürthauer, 2018). (unice.fr)
Se realizó un estudio cuasi-experimental modalidad antes y después sin grupo control, en 35 pacientes con clase II y III esqueletal, ingresados en la Consulta de Ortodoncia de la Clínica Universitaria de Especialidades Estomatológicas "Manuel Cedeño", en el período comprendido entre enero a noviembre de 2018. (sld.cu)

The widespread behavioural alterations observed in people with autism are accompanied by reports of structural and functional changes in the sensory and associative regions of the brain. (mpg.de)

In each case, PCP is critical to the function of these cells and tissues, and errors in the signaling system controlling PCP lead to human diseases and developmental defects, including congenital deafness, neural tube closure defects and cardiac outflow tract anomalies. (stanford.edu)

The position of the teeth inside the jaws and the shape of the occlusion are determined by developmental processes that act on these and their associated structures during the periods of formation, growth and postnatal modification. (sld.cu)

METHODS: To obtain reliable, subject-specific functional measures, we acquired 24 min of resting-state fMRI data from each subject. (bvsalud.org)
Violence-related content in video game may lead to functional con-nectivity changes in brain networks as revealed by fMRI-ICA in young men. (fzpe.de)

Together, these studies have led to the general consensus that individual learning performance is determined by activity or functional connections only within task-activated brain regions. (nature.com)

The last decade of laterality research has been bolstered by a significant broadening in theoretical framing and investigative approaches. (bbk.ac.uk)

This study also provided evidence that cilia-driven leftward flow is indispensable for the determination of laterality in rabbit embryos. (studylibde.com)

In cases where a child has been diagnosed with dyslexia, we strongly recommend a functional vision test. (thevisiontherapycenter.com)

Anatomy23

Organisms8

Diseases16

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Psychiatry and Psychology17

Phenomena and Processes14

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science2

Health Care3

Geographicals1

Transcranial Doppler ultrasound3

Asymmetry6

Lateralization4

Disorders8

Humans1

Asymmetries2

Directionality2

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Trajectories3

Cognitive3

Connectivity12

Biology1

Calcium2

Indices1

Intrinsic2

Disorder2

Cortex2

Physiology2

One's1

Neuroscience1

Development4

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FTCD2

Organization3

Behavioral1

Differences2

Stages1

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Genetic1

Bias2

Language1

Cellular1

Tasks1

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Structural and functional1

Human1

Processes1

FMRI2

Studies1

Research1

Study1

Cases1