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  • water
  • Typhoid is spread by eating or drinking food or water contaminated with the feces of an infected person. (wikipedia.org)
  • therapeutics
  • Dr Ryan is President of AVANT Immunotherapeutics, which discovers and develops innovative vaccines and therapeutics that harness the human immune system to prevent and treat disease. (bris.ac.uk)
  • This report provides comprehensive information on the therapeutic development for Typhoid Fever, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. (marketresearch.com)
  • infectious
  • to try to gauge future developments and suggest a reasonable organization to provide medical and nursing care for current cases of infectious disease and be capable of expansion to deal with any epidemic situation. (johnpowell.net)
  • serotypes
  • Nevertheless, ongoing disease due to vaccine serotypes such as 19A is observed in the elderly, suggesting a reservoir of carriage in the community. (ox.ac.uk)
  • paratyphi
  • Salmonella enterica serotype Paratyphi A is a human-restricted pathogen and the cause of paratyphoid A fever. (asm.org)
  • However, in recent years a Salmonella paratyphi A strain that is naturally devoid of capsule has caused frequent outbreaks of typhoid fever in Southern China, leading to the need for identification of additional antigens that could be incorporated into new vaccines. (pacific.edu)
  • As the spaO and h1a genes of S. paratyphi A are sequence conserved, extensively distributed and highly expressed, the rSpaO and rH1a immunogens should be considered in the development of novel vaccines to prevent S. paratyphi A-caused typhoid fever. (pacific.edu)
  • develop vaccines
  • But, according to Ted Fjällman, PhD, CEO of Prokarium, a UK synthetic biology company that has secured £2m from UK and Mexican Government contracts to develop vaccines against plague, Zika, bacterial diarrhoea and enteric fever, the biggest challenge is to speed up the R&D of new vaccines and allow clinical trials to be performed in a fast track mode, if and when there are signs of an epidemic unfolding. (pharmaceutical-technology.com)
  • subunit
  • The vaccinations under development in the Phase III clinical trials include Herpes Zoster Subunit (HZ/su), a recombinant version of the "Shingles Vaccine", which is determined to be successful in 51% of the tested adults, aged 60 and above, however the effectiveness is found to decrease with age. (grandviewresearch.com)
  • deaths
  • Typhoid fever is a major public health problem in developing countries, conservatively estimated to occur in 17 million cases and be responsible for 200,000 deaths annually. (asm.org)
  • Salmonella enterica subspecies enterica serotype Typhi is responsible for 17 million new cases of typhoid fever and 200,000 deaths annually ( 5 ). (asm.org)
  • clinical trials
  • Moreover, Merck & Co., Inc., and Oklahoma Medical Research Foundation have engaged in a collaborative research endeavor to develop the therapeutic Alzheimer's vaccine, CAD106 vaccine, which is under phase II clinical trials. (grandviewresearch.com)
  • Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. (giichinese.com.tw)
  • polio
  • Biological E and Statens Serum Institut (SSI) entered into a technology transfer arrangement for inactivated polio vaccine in 2013 and technology transfer was started immediately. (biologicale.com)