Development dental plaque is biofilm biofilms. Medical search. Frequent questions

Dental caries are also associated with poverty, poor cleaning of the mouth, and receding gums resulting in exposure of the roots of the teeth. (wikipedia.org)
Prevention of dental caries includes regular cleaning of the teeth, a diet low in sugar, and small amounts of fluoride. (wikipedia.org)
Treating a mother's dental caries may decrease the risk in her children by decreasing the number of certain bacteria she may spread to them. (wikipedia.org)
Worldwide, approximately 3.6 billion people (48% of the population) have dental caries in their permanent teeth as of 2016. (wikipedia.org)
The World Health Organization estimates that nearly all adults have dental caries at some point in time. (wikipedia.org)
A lesion that appears dark brown and shiny suggests dental caries were once present but the demineralization process has stopped, leaving a stain. (wikipedia.org)
Dental caries can also cause bad breath and foul tastes. (wikipedia.org)
The pathogenic bacterial complex can lead to dental caries, periodontitis and gingivitis. (encyclopedia.pub)
It was shown that 40-50% of plaque remains after tooth brushing, and the effects of biofilm retention are clearly evident in the prevalence of caries, gingivitis and periodontal disease. (encyclopedia.pub)
Presence of plaque rich in bacteria (especially Streptococcus mutans ) directly destroys the enamel layer by dissolving tooth minerals (mainly hydroxyapatite, Ca 10(PO 4) 6(OH) 2) resulting in caries. (encyclopedia.pub)
In another report, the maximum concentrations of butyric (8.8 mM), propionic (33.7 mM), acetic (52.6 mM) and formic acids (5.8 mM) were also detected in dental plaques from caries-free and caries-susceptible young subjects [ 32 ]. (biomedcentral.com)
His group has applied engineering methods and nanotechnology to study bacterial-fungal biofilms in childhood caries and nanoparticles for caries prevention. (upenn.edu)
When considering the role of supragingival dental plaque in caries, the proportion of acid producing bacteria (particularly S. mutans ), has direct relevance to the pathogenicity of the plaque. (biomedcentral.com)
Hence, the factors influencing expression of gtf genes are very important for prevention of dental plaques, caries, gingivitis, gingival abscess and even bacteremia following dental manipulation. (biomedcentral.com)
Because the caries-causing plaque is highly acidic, the new therapy is able to precisely target areas of the teeth harboring pathogenic biofilms without harming the surrounding oral tissues or microbiota. (decisionsindentistry.com)
We used plaque samples from caries-active subjects to reconstruct these highly pathogenic biofilms on real human tooth enamel," says Koo. (decisionsindentistry.com)
Further studies in a rodent model that closely mirrors the stages of caries development in humans showed that twice-a-day rinses of ferumoxytol and hydrogen peroxide greatly reduced the severity of caries on all of the surfaces of the teeth and also completely blocked the formation of cavities in the enamel. (decisionsindentistry.com)
The etiologic role of oral biofilms in dental caries and periodontal diseases has been previously documented [ 9 ] . (encyclopedia.pub)
Majority of the studies, including clinical trials concerning biofilm research, are related to stomatognathic diseases and address a wide range of issues such as caries, periodontitis, and demineralization [ 10 ] . (encyclopedia.pub)
This has led to dental studies that focus on reducing caries incidence, improving the prognosis of periodontitis and decreasing halitosis and candidiasis. (scielo.edu.uy)
generando en la comunidad odontológica estudios con enfoque en: reducción de la incidencia de caries, mejorar el pronóstico de periodontitis y disminución de halitosis y candidiasis. (scielo.edu.uy)
In the last decade, the use of probiotics has generated interest within the dental community with the development of studies focused on reducing caries incidence, improving the prognosis of periodontitis, eliminating halitosis and infections such as oral candidiasis 4 , 7 , 9 . (scielo.edu.uy)
Dental caries results from surface demineralization caused by an organized biofilm exposed to fermentable carbohydrates from the diet [1]. (bvsalud.org)
Both are able to proliferate and survive in acidic media, resulting in an elevated potential for caries development [3,4]. (bvsalud.org)
In order to prevent the clinical appearance of dental caries and to reduce its progression, several products with antimicrobial activity can be used [5,6]. (bvsalud.org)

This involves adherence of food to the teeth and acid creation by the bacteria that makes up the dental plaque. (wikipedia.org)
Bacteria often switch from a free-living lifestyle to a surface adapted, structured lifestyle known as a biofilm. (southampton.ac.uk)
We found that subpopulations of biofilm bacteria undergo cell death and lysis as a feature of the Pseudomonas aeruginosa biofilm life cycle. (southampton.ac.uk)
We isolated and named this phage, showed that it becomes superinfective to its host during biofilm development, and found that it plays a role in phenotypic diversification of biofilm bacteria. (southampton.ac.uk)
moreover, commensal vaginal flora or dental plaque bacteria may create such complex microbial consortia. (am-online.org)
Bacteria frequently grow in communities called biofilms, which are aggregates of cells and polymers. (virology.ws)
Biofilms are medically important as they can allow bacteria to persist in host tissues and on catheters, and confer increased resistance to antibiotics and dessication. (virology.ws)
If not removed regularly, the biofilm undergoes maturation, which is connected with a progressive shift from a Gram-positive to a Gram-negative anaerobic species, which results in formation under the gingival surface, where bacteria grow profusely [ 1 ] . (encyclopedia.pub)
Periodontitis is a complex, chronic inflammatory disease caused by an abnormal host response to bacteria from dental plaque. (encyclopedia.pub)
Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)
Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)
These carbohydrates act as nutrients for biofilm bacteria, especially acidogenic and aciduric species. (bvsalud.org)

Van Leeuwenhoek, using his simple microscopes, first observed microorganisms on tooth surfaces and can be credited with the discovery of microbial biofilms. (cdc.gov)

However, these four criteria are not always enough to cause the disease and a sheltered environment promoting development of a cariogenic biofilm is required. (wikipedia.org)
To evaluate in vitro the effect of a red propolis ethanolic extract (RPE) in the prevention of growth of a cariogenic biofilm and its cytotoxic potential. (bvsalud.org)

Biofilms are increasingly recognised as the predominant mode of bacterial growth including within medical, engineered, and environmental contexts. (southampton.ac.uk)
We discovered that exogenous nitric oxide can act as a signal for the dispersal of bacterial biofilms. (southampton.ac.uk)
An increase in bacterial mutation rate can promote biofilm formation. (southampton.ac.uk)
Dental plaque is a community of microorganisms found on the surface of teeth or other hard surfaces like dentures and embedded in a matrix of polymers of both host and bacterial origin. (encyclopedia.pub)
Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
Materials with low surface energies are associated with a higher affinity for bacterial adhesion, and many dental materials present higher surface energies than natural enamel [ 14 ] [ 15 ] . (encyclopedia.pub)
Antibiotic sensitivity patterns showed concordance of bacterial cultures from dental plaque and oropharyngeal cavity in 13 patients. (who.int)

Tooth mineral is solubilized, thereby buffering the plaque and maintaining an environment suitable for Streptococcus mutans growth. (encyclopedia.pub)
Streptococcus mutans is associated with pathogenesis of oral cavity, gingivoperiodontal diseases and bacteremia following dental manipulations. (biomedcentral.com)
The most frequent oral infections include gingivoperiodontal diseases including gingivitis and periodontitis, are caused by dental plaque, which is a S. mutans produced biofilm[ 9 - 11 ]. (biomedcentral.com)
Cellulose membrane disks (13 mm, N=12) were used for biofilm formation (24 h) of S. mutans and L. casei , which were treated (1 min) with 0.4% RPE or 0.12% Chlorhexidine (CHX). (bvsalud.org)
Red propolis extract showed antibacterial activity against the tested strains, exhibited acceptable cytotoxicity and reduced the colonization of S. mutans and L. casei in a biofilm membrane model. (bvsalud.org)

Microorganisms attach to surfaces and develop biofilms. (cdc.gov)
Rediscovery of a microbiologic phenomenon, first described by van Leeuwenhoek, that microorganisms attach to and grow universally on exposed surfaces led to studies that revealed surface-associated microorganisms (biofilms) exhibited a distinct phenotype with respect to gene transcription and growth rate. (cdc.gov)
These biofilm microorganisms have been shown to elicit specific mechanisms for initial attachment to a surface, development of a community structure and ecosystem, and detachment. (cdc.gov)
5 ) in 1978 put forth a theory of biofilms that explained the mechanisms whereby microorganisms adhere to living and nonliving materials and the benefits accrued by this ecologic niche. (cdc.gov)

An example of a biofilm is the dental plaque on your teeth. (virology.ws)
Methacrylate-based resin composites and polymers are the main components of dental restorative materials used to address the restoration of carious and missing teeth [ 4 ] . (encyclopedia.pub)
Accessibility of such differed alternatives relying upon the kind of teeth is probably going to drive the market for dental air cleaning in the next couple of years. (tmrresearchblog.com)
The dental air polishers find wide use in decreasing plaque, biofilms, and stains, from the teeth. (tmrresearchblog.com)

We investigated the contribution of cell density to biofilm phenotypic resistance. (who.int)
When biofilms were resuspended before testing, phenotypic resistance remained, but organisms, when diluted to 1 x 10(3) cells/ml, were susceptible. (who.int)
These observations suggested that cell density has a role in the phenotypic resistance of biofilm, that neither the drug efflux pumps tested nor quorum sensing through Chk1p contributes to resistance, and that azole drug tolerance at high cell density differs mechanistically from tolerance at low cell density. (who.int)

The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)

Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. (cdc.gov)
A biofilm is an assemblage of surface-associated microbial cells that is enclosed in an extracellular polymeric substance matrix. (cdc.gov)
This can contribute to biofilm dispersal, and provides a mechanism for the release of extracellular DNA (eDNA) within biofilms. (southampton.ac.uk)
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular assemblies. (virology.ws)

Periodontal pathogens have been found in carotid and coronary atherosclerotic plaques. (medscape.com)
Dental plaque biofilm may promote oral and oropharyngeal colonization of respiratory pathogens in hospitalized subjects. (who.int)

The knowledge of specific traits of multi-species biofilms may contribute to better understanding of the etiology of infectious diseases, increase the effciency of energy production in microbial fuel cells and lower the cost of biofouling prevention. (am-online.org)

Sucrose fermentation causes pH to drop rapidly to 5.0 or less at the point where the plaque contacts the tooth enamel. (encyclopedia.pub)

A. oris induces the coaggregation of the early colonizers Streptococcus gordonii and Streptococcus sanguinis with the intermediate colonizer Fusobacterium nucleatum in oral biofilms [ 1 ]. (biomedcentral.com)

Zwitterionic polymers (ZPs) have unique features that resist protein adhesion and prevent biofilm formation while maintaining biocompatibility. (encyclopedia.pub)

Cells may also communicate via quorum sensing, which may in turn affect biofilm processes such as detachment. (cdc.gov)

In addition, dental biofilm, especially subgingival plaque in patients with periodontitis, has been associated with cardiovascular and respiratory disease and diabetes mellitus, and recently constituting a high risk for developing severe illness due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection [ 2 ] . (encyclopedia.pub)

The nanoparticles break apart dental plaque through a unique pH-activated antibiofilm mechanism. (decisionsindentistry.com)

Biofilms have great importance for public health because of their role in certain infectious diseases and importance in a variety of device-related infections. (cdc.gov)
6. Multi-species biofilms and the development of infections. (am-online.org)
Dental plaque is an ecologically dominant form of oral biofilm associated with cariogenic and periodontal infections. (encyclopedia.pub)
Flowchart showing the possible mechanisms linking oral/dental infections to systemic diseases. (medscape.com)

Two major thrusts in the last decade have dramatically impacted our understanding of biofilms: the utilization of the confocal laser scanning microscope to characterize biofilm ultrastructure, and an investigation of the genes involved in cell adhesion and biofilm formation. (cdc.gov)
Accordingly, novel materials that can resist biofilm formation have attracted significant attention. (encyclopedia.pub)
In the host-factors, the critical factor of microbiological interaction at the surface leads to biofilm formation [ 8 ] . (encyclopedia.pub)
The control group of biofilm formation was not submitted to any treatment. (bvsalud.org)

Le biofilm constitué par la plaque dentaire peut favoriser la colonisation orale et oropharyngée par des agents pathogènes respiratoires chez les sujets hospitalisés. (who.int)

Much additional work by our group and others' is now elucidating the nitric oxide and c-di-GMP-mediated signalling pathway, and its exploitation for biofilm control in medical and industrial contexts. (southampton.ac.uk)

3 ) used scanning and transmission electron microscopy to examine biofilms on trickling filters in a wastewater treatment plant and showed them to be composed of a variety of organisms (based on cell morphology). (cdc.gov)
Biofilms that formed in microtiter plate wells, like high-density planktonic organisms, were resistant to drugs. (who.int)
A fluconazole-resistant strain showed greater resistance at high planktonic cell density, in biofilm, and in resuspended biofilm than did low-density planktonic or biofilm organisms. (who.int)

This tolerance often links biofilms with persistent and chronic infection, and provides ideal conditions for the acquisition or evolution of AMR. (southampton.ac.uk)

Biofilms are notorious for their resistance to environmental stresses, including antimicrobial compounds. (southampton.ac.uk)
Treatment of biofilms with nitric oxide also reduced their resistance to antimicrobial compounds. (southampton.ac.uk)

Dr. Blatz is the recipient of multiple teaching and research awards and has published and lectured extensively on dental esthetics, restorative materials, and implant dentistry. (upenn.edu)

We showed that strains of Pseudomonas aeruginosa with increased mutation rates (caused by deletion of genes involved in DNA mismatch repair) produced more biofilm biomass in laboratory experiments. (southampton.ac.uk)

The improved scientific evidence also indicates an active interaction at the dental materials and oral biofilm interface. (encyclopedia.pub)
Nevertheless, it is essential to note that the interfacial interaction between the dental material and biofilm is multifactorial. (encyclopedia.pub)

Such high predominance of dental issues is probably going to foreshadow well for the market over the time period of investigation, from 2019 to 2029. (tmrresearchblog.com)

These biofilms can be also found in the industrial water distribution systems, on surfaces of the metalworking fluids tanks, in food production plants, etc. (am-online.org)
Most of them attach to different surfaces to form some type of biofilm matrix that is highly structured and spatially organized. (encyclopedia.pub)
Biofilms are formed on surfaces inside the oral cavity covered by the acquired pellicle and develop into a complex, dynamic, microbial environment. (encyclopedia.pub)

The last few decades have seen notable developments in dental materials, and properties such as adhesion to the tooth surface and biomimetics have been extensively explored [ 1 ] . (encyclopedia.pub)

20 generations, a few days of biofilm growth) within biofilms. (southampton.ac.uk)
The issue free way and proficiency of this framework is foreseen to promote the growth of the dental air cleaning market in the years to come. (tmrresearchblog.com)

Dental plaque, which leads to oral diseases, may be a risk factor causing a severe course of COVID-19 similar to those in above mentioned chronic diseases. (encyclopedia.pub)

Oral streptococci are important components of the complex oral biofilm known as dental plaque. (biomedcentral.com)

A widely published and internationally respected lecturer, Dr. Blatz's main focus within clinical practice and research is esthetic dentistry with an emphasis on implantology and dental materials, particularly ceramics and adhesion. (upenn.edu)

Multi-species biofilms form in many natural settings: water, soil or even on dust particles in the air. (am-online.org)
Dental biomaterials form the backbone, which helps prevent, restore, and rehabilitate oral form and function. (encyclopedia.pub)

Dr. Koo's research focuses on understanding how biofilms cause oral infectious diseases and seeking new therapeutic strategies to control biofilms. (upenn.edu)
Oral biofilm is a causative factor of dental and periodontal diseases. (encyclopedia.pub)

This approach is providing new technologies and strategies to control biofilms in industrial and medical settings. (southampton.ac.uk)

How to gain and use knowledge about multi-species biofilms? (am-online.org)
Confocal microscopy in conjunction with fluorescence in situ hybridization as well as the atomic force microscopy are both very useful techniques to study the three-dimensional structure of the mixed-species biofilms. (am-online.org)
However, many technical obstacles may occur with these consortia during experimentation, e.g., how to grow multi-species biofilms with high reproducibility regarding the quantitative composition of these communities, and whether it is possible to quantitative by assess the metabolic activity and virulence of particular species when grown together in multi-species biofilm. (am-online.org)
2. Research methods in the multi-species biofilm studies. (am-online.org)
3. Dental plaque multi-species biofilm. (am-online.org)
4. Multi-species biofilms in water. (am-online.org)
5. Multi-species biofilms in industrial environment. (am-online.org)

On episode #368 of the science show This Week in Virology, a plaque of virologists explores the biology of Zika virus and recent outbreaks, and the contribution of a filamentous bacteriophage to the development of biofilms. (virology.ws)

Role of a new filamentous prophage Pf4 in Pseudomonas aeruginosa biofilm development. (southampton.ac.uk)

Since that time, the studies of biofilms in industrial and ecologic settings and in environments more relevant for public health have basically paralleled each other. (cdc.gov)

These glucans are important components of the matrix of cariogenic biofilms. (biomedcentral.com)

Tissue injury, flossing, dental treatment and even chewing and eating can induce blood vessel injury near spaces covered in dental plaque. (encyclopedia.pub)
This simulation showed that our treatment not only disrupts the biofilm but also prevents mineral destruction of the tooth's surface. (decisionsindentistry.com)

My research group aims to understand how biofilms develop and disperse and how they respond to environmental stresses including therapeutic compounds. (southampton.ac.uk)

Dental biomaterials differ from the hard tissues in the oral cavity in terms of both their physical and chemical properties. (encyclopedia.pub)

An established biofilm structure comprises microbial cells and EPS, has a defined architecture, and provides an optimal environment for the exchange of genetic material between cells. (cdc.gov)

Cell lysis as a feature of biofilm development. (southampton.ac.uk)
A strain lacking drug efflux pumps CDR1, CDR2, and MDR1, while susceptible at a low azole concentration, was resistant at high cell density and in biofilm. (who.int)
FK506, reported to abrogate tolerance to azole drugs at low cell density, had no effect on tolerance at high cell density and in biofilm. (who.int)

Based on observations of dental plaque and sessile communities in mountain streams, Costerton et al. (cdc.gov)

By using a specific polysaccharide-stain called Ruthenium red and coupling this with osmium tetroxide fixative, these researchers were also able to show that the matrix material surrounding and enclosing cells in these biofilms was polysaccharide. (cdc.gov)
Biofilms of Candida albicans are less susceptible to many antifungal drugs than are planktonic yeast cells. (who.int)

Les schémas de sensibilité aux antibiotiques ont montré une concordance au niveau des cultures bactériennes issues de la plaque dentaire et de la cavité oropharyngée chez 13 patients. (who.int)

Anatomy15

Organisms38

Diseases26

Chemicals and Drugs47

Analytical, Diagnostic and Therapeutic Techniques and Equipment52

Psychiatry and Psychology2

Phenomena and Processes22

Disciplines and Occupations10

Anthropology, Education, Sociology and Social Phenomena7

Technology, Industry, Agriculture18

Humanities1

Information Science3

Named Groups8

Health Care44

Caries25

Bacteria13

Microbial biofilms1

Cariogenic biofilm2

Bacterial7

Mutans5

Microorganisms4

Teeth4

Phenotypic3

Disrupt1

Extracellular4

Pathogens2

Etiology1

Enamel1

Streptococcus1

Polymers1

Quorum1

Periodontitis1

Nanoparticles1

Infections4

Formation4

Colonisation1

Signalling pathway1

Organisms3

Persistent1

Resistance2

Restorative materials1

Genes1

Interaction2

20191

Surfaces3

Tooth surface1

Growth2

Chronic1

Streptococci1

Clinical1

Form2

Diseases2

Control1

Species7

Contribution1

Filamentous1

Studies1

Important1

Treatment2

Develop1

Tissues1

Environment1

Cell3

Communities1

Cells2

Patients1