Determine the tissue distribution. Medical search. Frequent questions

It does not provide any information on the distribution of the adipose tissue in the organism. (hindawi.com)
The conducted studies have revealed that it is necessary to determine the adipose tissue distribution in the organism. (hindawi.com)
Further supporting this hypothesis, accurate predictions have been reported for acidic and neutral drugs in these same tissues and also for the same basic lipophilic drugs in tissues with less abundant lysosomes (e.g., brain, muscle, and adipose tissue). (aspetjournals.org)
Cancer-associated cachexia -- a condition that manifests as a loss of body weight, specifically of skeletal muscle and adipose tissue -- is a significant contributor to morbidity and mortality in patients with non-small cell lung cancer, wrote a team led by Dr. Othman Al-Sawaf of University College London Cancer Institute in the U.K. (auntminnie.com)
The team found that patients with 20% or more loss of skeletal muscle or adipose tissue at the time they were diagnosed had lower lung-cancer specific and overall survival rates. (auntminnie.com)
But one of the study's most important findings was that there is an association between circulating GDF15 (a gene that regulates inflammatory pathways, angiogenesis, cell repair and cell growth) and loss of body weight, skeletal muscle, and adipose tissue, which the investigators noted supports "the potential therapeutic relevance of targeting GDF15 in the management of CAC. (auntminnie.com)
Adipose tissue inflammation appears to be a risk factor for the progression of chronic kidney disease (CKD), but the effect of CKD on adipose tissue inflammation is poorly understood. (mdpi.com)
The purpose of this study was to clarify the involvement of uremic toxins (indoxyl sulfate (IS), 3-indoleacetic acid, p-cresyl sulfate and kynurenic acid) on CKD-induced adipose tissue inflammation. (mdpi.com)
In obese patients, although circulating concentrations of cortisol are not consistently elevated, the conversion of the inactive cortisol precursor (called cortisone) to active cortisol in adipose tissue may be abnormal. (dietdetective.com)
The cellular character of the adipose tissue of 21 nonobese and 78 obese patients has been examined. (jci.org)

Its receptor - the neurokinin type 1 - is distributed over cytoplasmic membranes of many cell types (neurons, glia, endothelia of capillaries and lymphatics, fibroblasts, stem cells, white blood cells) in many tissues and organs. (wikipedia.org)
39 An establishment that stores cells, tissues or organs must ensure that any of them that are untested or for which the results of tests on donor blood samples are positive or reactive for transmissible disease agents or markers or are unavailable are segregated from all other cells, tissues and organs. (gc.ca)
41 (1) A source establishment that distributes cells, tissues or organs under section 40 must keep a copy of the notice of exceptional distribution in its records. (gc.ca)
ii) if the cells, tissues or organs were imported, the establishment that imported them. (gc.ca)
2) If the establishment that receives a notice under subsection (1) is the establishment that imported the implicated cells, tissues or organs, it only has to notify the source establishment. (gc.ca)
Open to individuals involved or interested in the banking of cells, organs, eyes, or tissues who support our objectives, policies, and ethical standards. (aatb.org)
Advances in microfabrication, stem cell technology, tissue engineering, and mathematical modeling have created unprecedented in vitro models-organs-on-a-chip (OOC) systems-to predict risk and efficacy of drugs candidates, and accelerate their steps to the market. (mdpi.com)
In order to do this justification assessment, the radiation exposure and absorbed dose to various organs and tissues have to be thoroughly determined. (lu.se)

The original discovery of Substance P (SP) was in 1931 by Ulf von Euler and John H. Gaddum as a tissue extract that caused intestinal contraction in vitro. (wikipedia.org)
Partition coefficients were experimentally determined in rat tissues and blood samples using an in vitro vial equilibration technique. (cdc.gov)

If Aa penetrates through the junctional epithelium and underlying connective tissue, it can reach the root cementum surface and bone tissue and install in these locations, which makes difficult its eradication through mechanical means. (bvsalud.org)
Mycetoma is a chronic, progressively destructive inflammatory disease of the skin, subcutaneous and connective tissue, muscle and bone. (who.int)

Previous reports suggest that the dilution, homogenization, and incubation process necessary to determine unbound tissue fraction by equilibrium dialysis may disrupt or destroy intracellular components that contribute to distribution in vivo. (aspetjournals.org)
In vivo distribution of ACNVs was detected in healthy and tumor-bearing mice after scavenger receptors (SRs) blockade. (dovepress.com)

A physiologically based pharmacokinetic (PBPK) model to describe the absorption, distribution, metabolism, and elimination of methyl ethyl ketone (MEK) in rats was developed. (cdc.gov)
Cortisol and glucocorticoids in general play an important role in determining adipose (fat) tissue metabolism and distribution of body fat. (dietdetective.com)

During the development of an organism, tissues are sculpted into different three-dimensional forms. (elifesciences.org)

Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
The defect in the myosin motor activity in these mutants is evident in developing Drosophila embryos where tissue recoil following laser ablation is decreased compared to wild-type tissue. (elifesciences.org)
Overall, our data highlights that myosin activity is required for rapid cell contraction and tissue folding in developing Drosophila embryos. (elifesciences.org)

We apply STAMP to a variety of developmental stages and tissues in Drosophila including adult ovaries. (bvsalud.org)

Higher T numbers indicate a larger tumor and/or more extensive spread to tissues surrounding the breast. (medscape.com)
The long-circulating and higher tumor accumulation of E/PCF-NPs resulted in complete ablation of breast tumor tissue through the enhanced photothermal effect by NIR laser irradiation-mediated cell apoptosis. (dovepress.com)
The investigators also reported that those patients who developed cancer-associated cachexia at relapse of lung cancer and showed loss of fatty or muscle tissue or body-mass weight loss had particular tumor genomic and transcriptomic profiles compared with people who didn't develop these features -- specifically "inflammatory signaling" and "epithelial-mesenchymal transitional pathways," the team wrote. (auntminnie.com)
The first solid tumor exomes to be investigated were from 11 breast and 11 colorectal cancer tissue samples. (frontiersin.org)
To account for this, the team created a standardized metric for nerve density to clarify the variation in distribution of nerves in the oral cavity, called normalized nerve density, and showed its importance in tumor progression. (newswise.com)
As a result, it was possible to determine the malignancy of a breast tumor with up to 95.8% accuracy. (reachmd.com)

Pharmacokinetic studies and tissue distributions were performed and detected by an ultra-high performance liquid chromatography/mass spectrometry system. (dovepress.com)
However, many of the critical pharmacokinetic implications can be derived from information regarding the overall extent of tissue binding estimated nonspecifically. (aspetjournals.org)
Producers Association (MPA), and Vinyl Acetate Toxicology Group (VATG), have spon- sored development of physiologically based pharmacokinetic (PBPK) models for nasal tis- sue dosimetry with, respectively, acrylic acid (AA), methyl methacrylate (MMA), and vinyl acetate (VA). These compounds cause lesions in nasal epithelial tissues and are clas- sified as "Category 1" gases within the U.S. EPA (1994) classification scheme. (cdc.gov)

By segmenting CVH brain tissues into cerebrospinal fluid (CSF), gray matter (GM), white matter (WM), or other anatomical structures, we can study human brain and apply it in various fields, such as anatomical education, medical image interpretation, and disease diagnosis [ 3 ]. (hindawi.com)
Cerebrospinal fluid levels of chlorambucil have not been determined. (nih.gov)

The rate of increase of FEP and the latent period were influenced by the percentage absorption of the lead from the gastrointestinal tract, the distribution of absorbed lead within the body and the rate of release of new erythrocytes from the bone marrow into the peripheral blood (Cools et al. (inchem.org)

Here, we determine the embryonic ontogeny of the two main striatal pathways (striatonigral and striatopallidal) and identify novel (non)cell-autonomous roles for the axon guidance receptor Frizzled3 in uncharacterized aspects of striatal pathway formation (i.e., anterior-posterior axon guidance in the striatum and axon entry into the globus pallidus). (jneurosci.org)
Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. (ca.gov)
In contrast, CD135(+)GFP(+) hESCs gave rise to tissues representing all three embryonic germ layers, and were virtually indistinguishable from CD135(-)-derived tissues. (ca.gov)

In many cases, transporters exhibit extremely high Gini coefficients, even when their supposed substrates might be expected to be available to all tissues, indicating a much higher degree of specialisation than is usually assumed. (biorxiv.org)
By contrast, the Gini coefficients for ABC transporters tend to be larger in cell lines than in tissues, implying that some kind of a selection process has taken place. (biorxiv.org)

The cell viability, reactive oxygen species (ROS) levels, ratios of oxidized nicotinamide adenine dinucleotide to its reduced form (NAD + /NADH), apoptosis assays, and cellular uptake of E/PCF-NPs were determined on 4T1 cells. (dovepress.com)
Holotomography is used to image a microscopic label-free three-dimensional object in real time, such as tissues or cells using a laser. (news-medical.net)
Holotomography can determine the morphological, chemical, and mechanical properties of cells, including the presence of viral infection which is associated with unusually high refractive index values. (news-medical.net)
Macrophages are specialized immune cells that promote tissue inflammation by secreting inflammatory molecules, which can lead to insulin resistance and metabolic disease. (sciencedaily.com)
Further, our results link Frizzled3 to corridor guidepost cell development and suggest that an abnormal distribution of these cells has unexpected, widespread effects on the development of different axon tracts (i.e., striatal and thalamocortical axons). (jneurosci.org)
Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
In this study, immunohistochemistry revealed the CD11b + cells (neutrophils, macrophages/monocytes) present in the CL after luteal P4 synthesis ceased were distributed throughout the tissue. (bioone.org)
To determine if the immune cells that enter luteal tissue during structural regression are functionally different from those that are present during peak function, CD11b + or CD16 + populations were enriched from mid-late stage (functional) and regressing (days 1.8 ± 0.3 postmenses) CL using antibody-conjugated magnetic microbeads. (bioone.org)
Adipose cell size (lipid per cell) was determined in three different subcutaneous and deep fat depots in each patient and the total number of adipose cells in the body estimated by division of total body fat by various combinations of the adipose cell sizes at six different sites. (jci.org)
These data establish that subpopulations of proliferating hESCs whose tissue fate is predetermined exist, and challenge the notion that all cells within proliferating hESC cultures are truly 'pluripotent. (ca.gov)
The stiffness levels and distributions of biological materials reflect disease-related information, from cells to tissues. (reachmd.com)
In the human body, iron is present in all cells and has several vital functions -- as a carrier of oxygen to the tissues from the lungs in the form of hemoglobin (Hb), as a facilitator of oxygen use and storage in the muscles as myoglobin, as a transport medium for electrons within the cells in the form of cytochromes, and as an integral part of enzyme reactions in various tissues. (cdc.gov)
Recent results showed that the fruit fly equivalent of CTPS drives fat cells to stick together, which is necessary to maintain and form fat tissue. (bvsalud.org)

However, multiple light scattering through large volumes of biological tissue prevents acquisition of clear images. (news-medical.net)
We illustrate where such mechanisms of pattern formation arise in biological systems from cellular to tissue scales, with an emphasis on morphogenesis. (mpi-cbg.de)

The Gini index (coefficient) characterises inequalities of distributions, and is used in a novel way to describe the distribution of the expression of each transporter among the different tissues and cell lines. (biorxiv.org)
means that to understand drug distributions we must understand transporter distributions. (biorxiv.org)
We showed that the 5-HT neurotoxin, 5,7-dihydroxytryptamine (5,7-DHT), reduces brain tissue 5-HT, decreases expression of 5-HT transporter (SERT) protein and increases expression of glial fibrillary acidic protein (GFAP). (erowid.org)

Recent studies suggest exosome-like nanovesicles (ELNVs) from fruits and vegetables are involved in tissue renewal process and functional regulation against inflammatory diseases or cancers. (dovepress.com)

The morphological alterations of prostate, breast, and skin tissues that have become cancerous can be examined by holotomography to observe specific scattering effects. (news-medical.net)
Many macroalgal species have biomechanical designs that minimize damage by these sources, such as flexibly reconfiguring into streamlined shapes in flow, having either strong or extensible tissues that are tough, and having chemical and morphological defenses against herbivores and epibionts. (frontiersin.org)
provides an ideal framework to study macroalgal damage that incorporates sources of injury in the environment, structural design and tissue material properties that resist or compensate for damage, and effects of morphological changes caused by breakage on the performance of the macroalgae in natural habitats, and thus on their survival and reproduction. (frontiersin.org)

In contrast, doses of (+/-)-3,4-methylenedioxymethamphetamine (MDMA) that decrease brain tissue 5-HT fail to alter expression of SERT or GFAP. (erowid.org)
Using a new and highly sensitive anti-SERT antibody, we determined if MDMA alters the subcellular distribution of SERT protein by measuring SERT expression in endosomes and plasma membranes 2 weeks after MDMA administration. (erowid.org)
Rat brain tissues (caudate, cortex, hippocampus) were collected 3 days and 2 weeks after MDMA (7.5 mg/kg i.p., q 2hr x 3 doses) or 5,7-DHT (150 microg/rat, icv) administration. (erowid.org)
At both 3 days and 2 weeks post-injection, MDMA decreased tissue 5-HT (60%) and had no effect on GFAP expression. (erowid.org)
These findings indicate that a dosing regimen of MDMA that depletes brain 5-HT does not alter SERT protein expression or the distribution of SERT between endosomes and the plasma membrane, and does not produce detectable evidence for neurotoxicity. (erowid.org)
In this study, regional tissue distributions of the amphetamine analogue 3,4-methylenedioxymethamphetamine MDMA, 'ecstasy' and its metabolite 3,4-methylenedioxyamphetamine MDA in a fatal overdose are presented. (erowid.org)

Furthermore, we reconstructed three-dimensional surfaces of these tissues, which show their potential in exploring the high-resolution anatomical structures of human brain. (hindawi.com)
The anatomical structures of the brain tissues are very complex and associated with a number of neurological diseases. (hindawi.com)
Once damage occurs, macroalgae have a variety of biomechanical responses, including increasing tissue strength, thickening support structures, or altering thallus shape. (frontiersin.org)
Both the tissue Pb concentrations, and tissue-blood Pb ratios were significantly higher in the bone structures of the young animals than in the adults. (inchem.org)
CTPS, a metabolic enzyme, forms filamentous structures termed cytoophidia in various tissues. (bvsalud.org)

42 A source establishment that distributes a cell, tissue or organ under section 40 before the donor suitability assessment is complete must, after the distribution, complete the assessment, carry out any other appropriate follow-up testing and notify the relevant transplant establishment of the results. (gc.ca)
Micro-tissue units, e.g., self-assembled, differentiated, 3D-printed or tissue-engineered units, were constructed within this microchip and microenvironment, and were engineered to recapitulate the specified/targeted tissue or organ responses. (mdpi.com)
The organ and tissue doses are calculated based on biokinetic models that are obtained by means of repeated gamma camera or PET-camera measurements of the distribution of the activity in the body and models of various physiological processes. (lu.se)

Precursor pool turnover rate, distribution volumes, and red blood cell-plasma concentration ratios were determined. (nih.gov)

Although, the non-muscle myosin II holoenzyme (myosin) is a molecular motor that powers contraction of actin cytoskeleton networks, recent studies have questioned the importance of myosin motor activity cell and tissue shape changes. (elifesciences.org)

Cell number has also been estimated on the basis of various assumed distribution of total fat between the subcutaneous and deep fat depots. (jci.org)
The disease commonly affects young adults, particularly men aged between 20 and 40 years.2 Infection is thought to be acquired by traumatic inoculation of fungi or bacteria into the subcutaneous tissue following minor trauma or a penetrating injury, commonly thorn pricks. (who.int)

These solubility ratios were in agreement with previous human-based estimates that MEK is uniformly soluble within all tissues. (cdc.gov)

In addition the activated ALAD activity was also determined: this was done in the presence of a chelating agent which removes the lead from the enzyme. (inchem.org)
To our knowledge, angiotensin converting enzyme ( ACE ) gene I/D polymorphisms have not yet been investigated in AS patients in Turkish population.This study was conducted in Turkish patients with AS to determine the frequency of I/D polymorphism genotypes of angiotensin converting enzyme gene. (molvis.org)
Previous research identified an enzyme, called CTP synthase (CTPS), which is produced in large amounts by the liver and fat tissue in mammals, and the equivalent in fruit flies, known as the fat body. (bvsalud.org)

Although advances in tissue typing and cross-match testing have helped to deter severe transplant rejection, rejection may result from direct cellular attack (cellular rejection) or be mediated by antibodies (humoral rejection). (medscape.com)

18 F]FB-IL2 kinetics in this animal model of inflammation could be best described by a reversible two-tissue compartment model. (springer.com)
To learn more about how the brain becomes inflamed, they looked at increases in the amount and location of fat tissue as well as levels of sex hormones and brain inflammation in male and female mice at different time intervals as they grew fatter on a high-fat diet. (neurosciencenews.com)

These models have been developed to gain a better understanding of both the physiologi- cal and anatomical characteristics of animal species and the physico- chemical characteristics of specific inhaled materials that determine the amounts of gases absorbed by tissues in various regions of the respiratory tract. (cdc.gov)

Considering the substantial differences in concentrations in blood samples taken from various sites in the body and the high levels in some tissues e.g., in liver, we concluded that the influence of postmortem redistribution should be taken into account in the interpretation of toxicological data when an appropriate peripheral sample cannot be obtained or when blood samples are not available because of putrefaction. (erowid.org)

For example, it has been suggested that disruption of the postnuclear fractions containing the acidic organelles (e.g., lysosomes) may explain reported under-predictions in the distribution of the basic lipophilic drugs imipramine, desipramine, chlorpromazine, and methadone from liver, lung, and kidney homogenates ( Clausen and Bickel, 1993 ). (aspetjournals.org)

They found again the distinctive patterns of fat distribution in males and females in response to a high-fat diet. (neurosciencenews.com)
A varied range of devices is used in various domains such as monitoring drug response during drug development, evaluating the bio-distribution patterns of new molecules, and cancer cell research. (grandviewresearch.com)

Online learning and education surrounding all aspects of tissue donation, tissue banking, research, and transplantation. (aatb.org)

DNeasy Blood & Tissue Kits are intended for molecular biology applications. (qiagen.com)
However, the regional microstructural tissue effects of these molecular mechanisms in the heart have yet to be spatially linked and further elucidated. (researchgate.net)
Taken together, CITED4 expression is necessary for exercise-induced regional remodeling of the heart's microstructural helicity revealing how a key molecular regulator of cardiac remodeling manifests into downstream local tissue-level changes. (researchgate.net)
Expression of transcription factor CITED4 is necessary for exercise-induced regional remodeling of the heart's microstructural helicity, revealing how a key molecular regulator of cardiac remodeling mediates local tissue-level changes. (researchgate.net)

Drug-target engagement assessment of new molecules or preclinical bio-distribution is critical in determining drug efficacy to optimize drug formulations and find suitable profiles. (grandviewresearch.com)
Work will be happening in collaboration with the provincial government of Saskatchewan and the Department of Fisheries and Oceans Canada to complete a standardized and unified assessment of lake sturgeon abundance and distribution. (alberta.ca)

Chlorambucil and its metabolites are extensively bound to plasma and tissue proteins. (nih.gov)
The laboratory is especially interested in transport proteins and their impact on tissue drug distribution and elimination. (uwo.ca)

We investigated whether Norwalk virus or viruslike particles bind specifically to oyster tissues after bioaccumulation or addition to tissue sections. (cdc.gov)
Since noroviruses attach to carbohydrates of the histo-blood group family, tests using immunohistochemical analysis were performed to evaluate specific binding of virus or viruslike particles to oyster tissues through these ligands. (cdc.gov)
We tested whether oysters can actively capture noroviruses and determined the fate of prototype genogroup I Norwalk virus particles in bioaccumulation experiments. (cdc.gov)

A peculiar characteristic that makes it important and that hinders its elimination is its high capacity for tissues invasion. (bvsalud.org)

These data show that the oyster can selectively concentrate a human pathogen and that conventional depuration will not eliminate noroviruses from oyster tissue. (cdc.gov)
These methods need accurate estimation of probability density function and for those images with largely overlapped tissues, it is hard to match real distribution of data in a high accuracy. (hindawi.com)
PET data were analysed using Logan and Patlak analysis as well as one-tissue and two-tissue compartment models. (springer.com)
AIC indicated that data could be modelled best by a two-tissue reversible compartment model. (springer.com)
The injection sites were imaged using optical coherence tomography (OCT) amplitude data to determine injection depth. (spie.org)
Participants emphasized several generic data needs in relation to nasal vapor uptake studies in human subjects, to broader discussion of tissue diffusion models, and to extensions to other classes of gases. (cdc.gov)
The global burden of mycetoma cannot be determined accurately as there is a lack of accurate data on its incidence, prevalence and distribution. (who.int)

Similar trends hold true for the expression profiles of transporters in different cell lines, suggesting that cell lines exhibit largely similar transport behaviour to that of tissues. (biorxiv.org)

Tissue residue distribution and withdrawal time estimation of trimethoprim and sulfachloropyridazine in Yugan black-bone fowl ( Gallus gallus domesticus Brisson). (cabi.org)

Univariate Cox regression analysis showed that Annexin A2 and S100A10 in stromal tissue correlated with shorter overall survival (OS). (cancerindex.org)

We analyse two comprehensive transcriptome datasets from human tissues and human-derived cell lines in terms of the expression profiles of the SLC and ABC families of membrane transporters. (biorxiv.org)
Expression of Annexin A2 and S100A10 was evaluated in EOC tissue samples (n=303) by immunohistochemistry. (cancerindex.org)
Moreover, the role of nuclear receptors in determining the expression of drug metabolizing enzymes and transporters is also an area of interest. (uwo.ca)
Quantification of CITED4 expression and microstructural tissue helicity reveals a significant correlation across both sedentary and exercise mouse cohorts. (researchgate.net)

After 10 minutes, cerebral blood FDG activity levels were found to be a minor fraction of tissue activity. (nih.gov)

Scattering parameters of a tissue can be determined as laser light passes through significant volumes of tissue. (news-medical.net)

With relatively few assumptions, qualitative insight into the extent of tissue binding is easily obtained by pairing distribution measures with unbound plasma fraction. (aspetjournals.org)

This study aimed to determine the tissue residue depletion kinetics of trimethoprim and. (cabi.org)
Assessing lung cancer sufferers' body composition with CT imaging can help clinicians determine whether patients have developed cancer-associated cachexia (CAC), and thus assess prognosis, according to a study published April 12 in Nature Medicine . (auntminnie.com)
This study was conducted to determine the distribution of [14C]C60 in the pregnant rat and fetuses, and in the lactating rat and offspring. (rti.org)

Cryosection brain images in Chinese Visible Human (CVH) dataset contain rich anatomical structure information of tissues because of its high resolution (e.g., 0.167 mm per pixel). (hindawi.com)
In this paper, we propose a supervised learning-based CVH brain tissues segmentation method that uses stacked autoencoder (SAE) to automatically learn the deep feature representations. (hindawi.com)
Experimental results validated the effectiveness of our method and showed that it outperformed four other classical brain tissue detection strategies. (hindawi.com)
Unbound fractions in mouse brain and plasma were determined for 31 structurally diverse central nervous system (CNS) drugs and two active metabolites. (aspetjournals.org)

The TRACKMAN Connected system guides researchers through the DNeasy Blood & Tissue protocols while automatically adjusting the Bluetooth-enabled PIPETMAN M Connected pipette settings. (qiagen.com)
Normalized nerve density provides researchers with another datapoint to determine the best course of treatment. (newswise.com)

The only accreditation program for tissue establishments, recognizing the highest commitment to the quality and safety of donated human tissue. (aatb.org)
A PCT system, the ECAT, was used to determine the rate constants, lumped constant, and stability of the model in human beings. (nih.gov)
Most of the work was done with human tissue and the team then validated the findings using a mouse model. (newswise.com)

Injected tissue was rapidly frozen and sectioned with a keratome to reveal the mixture dispersion with a fluorescence microscope. (spie.org)
Noninvasive near infrared (NIR) fluorescence imaging provides visualization and detection of full body tissue bio-distribution of a new drug in real-time. (grandviewresearch.com)

The efficient DNeasy Blood & Tissue procedure enables high yields of total DNA from animal blood and tissue samples (see table Typical DNA yields from animal tissues using DNeasy Blood & Tissue Kits and figure DNA yields. DNA was purified from 100 µl whole blood using the DNeasy Blood & Tissue Kit. Goat : DNA was purified from 50 µl goat whole blood. Using more than 50 µl goat blood gave no significant increase in DNA yield. Chicken : DNA was purified from 5 µl chicken whole blood. Bird blood contains nucleated erythrocytes, giving higher DNA yields than mammalian blood. "> DNA yields ). (qiagen.com)
Tissue samples were collected from primary pterygia, recurrent pterygia, and normal conjunctiva to perform the following experiments: immunohistochemical measurement of IPO13 and K17. (molvis.org)

In addition, some methods estimate distribution of each class with probability density of Gaussian mixture model [ 6 ]. (hindawi.com)
The optical phase of laser is affected by transmission through an object, such that the resulting difference in the phase of light upon recombination can be used to determine the density of a sample. (news-medical.net)
They used adjacent tissue to compare and determine a "normalized" density for different regions in the oral cavity. (newswise.com)

Norwalk virus strain 8FIIa was purified from a stool sample of an infected volunteer and assayed by reverse transcription-polymerase chain reaction (RT-PCR) endpoint dilution (RT-PCR units) to determine the amount of viral RNA in the sample ( 19 ). (cdc.gov)

Tracer techniques and quantitative autoradiographic and tissue counting models for measurement of metabolic rates were combined with positron computed tomography (PCT) and (F-18)2-fluoro-2-deoxy-D-glucose (FDG) for the measurement of local cerebral metabolic rate for glucose (LCMRGlc) in humans. (nih.gov)

Macroalgae provide food and habitat to a diversity of organisms in marine systems, so structural damage and breakage of thallus tissue can have important ecological consequences for the composition and dynamics of marine communities. (frontiersin.org)

Ultrasound elastography can non-invasively determine the degree and shape of the tissue stiffness and is used for diagnosing breast cancer due to its low cost. (reachmd.com)

The team also expects the device to be helpful in low-power and high-accuracy disease diagnosis and applications such as robotic surgery where a surgical site needs to be quickly determined in an environment humans cannot directly contact. (reachmd.com)

Since noroviruses can attach to carbohydrates of the ABH and Lewis histo-blood group family in humans, we also examined the possibility of a similar specific binding to oyster tissues through related carbohydrates ( 17 , 18 ). (cdc.gov)
DNeasy Blood & Tissue Kits provide fast, easy silica-based DNA extraction without phenol or chloroform in convenient spin-column and 96-well-plate formats. (qiagen.com)
Extracting DNA using the DNeasy Blood & Tissue Kit can be automated on the QIAcube Connect . (qiagen.com)
DNeasy Blood & Tissue standard protocols can also be executed using the TRACKMAN Connected system, paired with PIPETMAN M Connected pipettes, both from Gilson. (qiagen.com)
In partnership with My Green Lab, we've also assessed the environmental impact of the DNeasy Blood & Tissue Kit (250). (qiagen.com)
For an eco-friendlier alternative to this kit, see our QIAwave DNA Blood & Tissue Kit . (qiagen.com)
The distribution between blood components did not vary significantly with age. (inchem.org)
1976, 1977) have determined the ALAD activity, and the lead level in the blood of 47 urban mothers, and in the cord blood of their infants. (inchem.org)

The lowest four in tissues are FAM32A, ABCB7, MRPL21 and PCBP1, while the lowest three in cell lines are SF3B2, NXF1 and RBM45. (biorxiv.org)
PCBP1 is both reasonably highly expressed and has a low Gini coefficient in both tissues and cell lines, and is an excellent novel housekeeping gene. (biorxiv.org)
Altogether there are four main datasets, namely 409 "SLCs" in 59 tissue types and 56 cell lines, and 48 ABCs in the same tissue types and cell lines. (biorxiv.org)
Non-muscle cell contractility is critical for tissues to adopt shape changes. (elifesciences.org)
Cell shape changes and cell movements drive these tissue-scale transformations. (elifesciences.org)
This co-culture approach also will enable identification of other distinct hESC subpopulations, and selection for these should prove valuable in generating tissue-specific reagents for cell-based therapy. (ca.gov)

Other methods, like region growing, extend threshold by combining it with connectivity, but they need seeds for each region and have the problem for determining suitable threshold for homogeneity. (hindawi.com)

The exact amount of radioactivity in the application solution was determined by Liquid Scinitillation Counting (LSC) resulting in 21.5 MBq, equivalent to 308 mg of undiluted 14C-Silan 449029 VP. (europa.eu)

The causative organisms can be detected by examining either the discharge from wounds or surgical tissue biopsies. (who.int)

Anatomy48

Organisms29

Diseases5

Chemicals and Drugs76

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Phenomena and Processes52

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture4

Information Science4

Health Care1

Adipose tissue10

Organs8

Vitro2

Connective tissue2

Vivo2

Metabolism2

Organism1

Embryos3

Drosophila1

Tumor6

Pharmacokinetic3

Cerebrospinal2

Gastrointestinal tract1

Embryonic3

Coefficients2

Cells13

Biological2

Transporter3

Inflammatory1

Morphological3

MDMA6

Structures5

Organ3

Precursor1

Contraction1

Subcutaneous2

Ratios1

Enzyme3

Cellular1

Inflammation2

Amounts1

Concentrations1

Liver1

Patterns2

Transplantation1

Molecular4

Assessment2

Proteins2

Particles3

Elimination1

Data7

Largely1

Bone1

Regression1

Expression4

Levels1

Volumes1

Fraction1

Study3

Brain4

Researchers2

Human3

Fluorescence2

Samples2

Density3

Dilution1

Metabolic1

Structural1

Breast1

High1

Blood8

Cell6

Suitable1

Radioactivity1

Surgical1