BenzamidesPiperazinesPyrimidinesCardiotoxinsToxicity TestsDiphenylcarbazideGastrointestinal Stromal TumorsDrugs, InvestigationalFusion Proteins, bcr-ablAntineoplastic AgentsProto-Oncogene Proteins c-kitProtein Kinase InhibitorsTransplantation ConditioningHematopoietic Stem Cell TransplantationReceptor, Platelet-Derived Growth Factor alphaLeukemia, Myeloid, Chronic-PhaseDose-Response Relationship, DrugLiverReceptor, Platelet-Derived Growth Factor betaDrug Resistance, NeoplasmBlast CrisisHypereosinophilic SyndromeGenes, ablCytogenetic AnalysisProto-Oncogene Proteins c-ablProtein-Tyrosine KinasesHypopigmentationK562 CellsGastrointestinal NeoplasmsTreatment OutcomePhiladelphia ChromosomeLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeRemission InductionReceptors, Platelet-Derived Growth FactorEnzyme InhibitorsDermatofibrosarcomaMastocytosis, SystemicDrug ApprovalCell Line, TumorThiazolesDisease-Free SurvivalPregnatrienesFibromatosis, AggressiveAntineoplastic Combined Chemotherapy ProtocolsAdministration, OralDrug Administration ScheduleProto-Oncogene Proteins c-sisTime FactorsApoptosisHarringtoninesLeukemia, Myeloid, Accelerated PhaseCell ProliferationSurvival AnalysisInterferon-alphaMutationDrug SynergismLichenoid EruptionsPhosphorylationmRNA Cleavage and Polyadenylation FactorsNeoplasm, ResidualSurvival RateSalvage TherapyPrognosisKetonesPyrrolesDisease ProgressionCell SurvivalToxicity Tests, AcuteTreatment FailureGene Expression Regulation, LeukemicUnited States Food and Drug AdministrationReverse Transcriptase Polymerase Chain ReactionFuransCytogeneticsCombined Modality TherapyRifabutinSignal TransductionRecurrencePrimary MyelofibrosisRNA, MessengerHydroxyureaOrgan TransplantationTissue and Organ ProcurementIn Situ Hybridization, FluorescenceInhibitory Concentration 50Chromosomes, Human, Pair 9Cells, CulturedNeoplastic Stem CellsPlatelet-Derived Growth FactorFollow-Up StudiesSTAT5 Transcription FactorPrecursor Cell Lymphoblastic Leukemia-LymphomaImmunohistochemistryScleroderma, SystemicBlood Cell CountIndolesStem Cell FactorHistiocytoma, Malignant FibrousGastrostomyBone Marrow