• To assess the incidence of and risk factors for clinical and subclinical dengue virus (DENV) infection, we prospectively studied 1,207 adult short-term travelers from the Netherlands to dengue-endemic areas. (cdc.gov)
  • The risk for DENV infection for short-term travelers to dengue-endemic areas is substantial. (cdc.gov)
  • Primary infection with 1 serotype confers lifelong immunity to that serotype but increases the risk for severe dengue illness after secondary infection with another serotype ( 6 ). (cdc.gov)
  • Most other epidemiologic studies are retrospective and focus on symptomatic patients who seek care at a clinical site, thus disregarding the nonspecific nature of the infection and the increased number of travelers to dengue-endemic areas ( 5 , 8 , 9 , 12 , 13 ). (cdc.gov)
  • Dengue and dengue hemorrhagic fever (DHF) result from infection by any of four serotypes of dengue viruses. (cdc.gov)
  • And today's presentation I'll be covering the new guidance for U.S laboratories testing for Zika virus infection. (cdc.gov)
  • Following infection with one serotype, subsequent infection with a different serotype increases a person's risk of severe dengue and death. (paho.org)
  • Nevertheless, clinics in Brazil may not have adequate testing reliability as they rely on symptoms rather than PCR viral sequencing, which is expensive and time consuming, in many cases there may be co-infection with other similar mosquito-borne viruses. (wikipedia.org)
  • The oropouche virus is responsible for causing massive, explosive outbreaks in Latin American countries, making oropouche fever the second most common arboviral infection seen in Brazil. (wikipedia.org)
  • Z ported human infections indicated that clinical characteris- ika virus (ZIKV) is a mosquito-transmitted virus in the tics of infection with ZIKV included fever, headache, mal- family Flaviviridae and genus Flavivirus . (folkhalsomyndigheten.se)
  • The cases were later confirmed as Marburg virus infection by reverse transcriptase-polymerase chain reaction (RT-PCR) at the National Public Health Laboratory, Tanzania. (unamhe.or.ug)
  • Marburg virus infection often results from prolonged exposure to mines or caves inhabited by Rousettus bat colonies. (unamhe.or.ug)
  • Detection of ongoing/recent dengue virus infection by both molecular (RT-PCR) and serological methods (IgM) was available in 15/19 participating laboratories. (who.int)
  • Dengue is a mosquito-borne viral infection associated with significant morbidity and mortality caused by any of four closely related virus serotypes (DENV-1,-2,-3 and -4), all of which circulate in the World Health Organization (WHO) Western Pacific Region. (who.int)
  • 2. Musso D, Ko AI, Baud D. Zika Virus Infection - After the Pandemic. (rjppd.org)
  • Pathophysiology and Mechanisms of Zika Virus Infection in the Nervous System. (rjppd.org)
  • A review on Zika virus outbreak, epidemiology, transmission and infection dynamics. (rjppd.org)
  • Zika virus infection experimentally induced in a human volunteer, 442-448. (rjppd.org)
  • Zika virus infection with prolonged maternal viremia and fetal brain abnormalities. (rjppd.org)
  • Virus and antibody dynamics in acute West Nile virus infection. (rjppd.org)
  • This is because the immune response from the first infection increases the risk of developing DHF upon re-infection, a phenomenon known as antibody-dependent enhancement. (tanzirislambritto.com)
  • The primary cause of Dengue Hemorrhagic Fever (DHF) is infection by one of the four dengue virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). (tanzirislambritto.com)
  • Interestingly, it's not the first infection with the dengue virus that usually causes DHF but rather a subsequent infection with a different dengue serotype. (tanzirislambritto.com)
  • In ADE, antibodies from a first dengue infection fail to neutralize a second dengue virus of a different serotype during re-infection. (tanzirislambritto.com)
  • The primary response of our immune system to an infection is to produce specific antibodies that can neutralize the invading pathogen. (tanzirislambritto.com)
  • These antibodies will neutralize the virus and aid in its clearance, thus resolving the infection. (tanzirislambritto.com)
  • The antibodies from the first infection can't neutralize the new serotype effectively. (tanzirislambritto.com)
  • For instance, infants born to dengue-immune mothers are at a higher risk of severe disease due to the presence of maternal antibodies, which can enhance viral infection. (tanzirislambritto.com)
  • Suspected infection with Japanese Encephalitis virus and has travel to endemic area. (canada.ca)
  • A fourfold or greater increase or decrease in titre between the acute phase and convalescent phase serum is considered to be diagnostic of infection with Japanese Encephalitis virus. (canada.ca)
  • A 4 fold rise or greater in neutralizing antibody titre, is required to document a 'confirmed case' of infection with associated illness. (canada.ca)
  • Therefore, both basic infection research and diagnostic population screenings would benefit from improved methods to determine virus-neutralising activity in patient samples. (pasteur.fr)
  • Dengvaxia is approved for use in individuals 9 through 16 years of age with laboratory-confirmed previous dengue infection and living in endemic areas. (cdc.gov)
  • Previous dengue infection can be assessed through (a) medical records of a previous laboratory-confirmed dengue infection or (b) serological testing prior to vaccination . (cdc.gov)
  • The meetings provided up-to-date information on the current situation and agreed on a set of actions for the countries to undertake to enhance their preparedness and response capacities to Zika virus infection and its complications. (who.int)
  • Many medically important and emergent arboviruses (arthropod-borne viruses) originated in non-human primates (NHPs), which typically show no clinical signs of infection but become viraemic and help maintain the virus in nature [ 1 ]. (biomedcentral.com)
  • We propose that additional investigation into the role of ADCP in protective viral responses, the specific virus epitopes targeted by ADCP antibodies, and the types of phagocytes and Fc receptors involved in ADCP at sites of virus infection will provide insight into strategies to successfully leverage this important immune response for improved antiviral immunity through rational vaccine design. (frontiersin.org)
  • and monoclonal recombinant antibodies are also currently being pursued for prevention of HIV-1 infection in large Phase IIb clinical trials (NTC02716675 and NCT02568215). (frontiersin.org)
  • Pregnant women who reside in areas with ongoing Zika virus transmission have an ongoing risk for infection throughout their pregnancy. (cdc.gov)
  • Health care providers should discuss reproductive life plans, including pregnancy intention and timing, with women of reproductive age in the context of the potential risks associated with Zika virus infection. (cdc.gov)
  • Evidence suggesting an association of Zika virus infection with an increased risk for congenital microcephaly and other abnormalities of the brain and eye ( 5 ) prompted the World Health Organization to declare the Zika virus outbreak a Public Health Emergency of International Concern on February 1, 2016 ( http://www.who.int/mediacentre/news/statements/2016/1st-emergency-committee-zika/en/ external icon ). (cdc.gov)
  • There is currently no vaccine or medication to prevent Zika virus infection. (cdc.gov)
  • When the Zika epidemic spread through the American continent and then later to Africa and Asia in 2015, researchers compared the characteristics of the Zika infection to Dengue, considering both these viruses were transmitted primarily through the same vector, the Aedes aegypti female mosquitoes. (frontiersin.org)
  • During virus infection, the specific immune signals produced from infected cells are important for dictating the recruitment and activation of innate or adaptive immune cells that are required to fight virus infection. (nature.com)
  • For SARS-CoV-2, lung epithelial cells are the primary site of infection and therefore are responsible for initiating immune responses to virus infection. (nature.com)
  • In addition to direct viral sensing, cells have also evolved ways to detect the indirect effects of virus infection, such as nuclear or mitochondrial damage caused by the heavy cellular burden imposed by virus replication. (nature.com)
  • Moreover, cGAS is an important molecule for regulating basal expression levels of cell-intrinsic immune genes in cells and is, therefore, a central protein in immune responses to virus infection 10 . (nature.com)
  • However, the relationship between serum PFAS and antibody levels following SARS-CoV-2 infection or COVID-19 vaccination has not been examined. (cdc.gov)
  • We examined differences in peak immune response and the longitudinal decline of antibodies following SARS-CoV-2 infection and COVID-19 vaccination by serum PFAS levels in a cohort of essential workers in the United States. (cdc.gov)
  • Higher perfluorooctane sulfonic acid (PFOS), perfluorohexane sulfonic acid (PFHxS), and perfluorononanoic acid (PFNA) concentrations were associated with a lower peak antibody response after infection (p = 0.009, 0.031, 0.015). (cdc.gov)
  • Dengue virus infection has emerged as marker in clinical practice ( 11 ). (who.int)
  • Given that these enhanced responses are triggered by failed attempts to control the infecting virus, VAED typically presents with symptoms related to the target organ of the infection pathogen. (cov19longhaulfoundation.org)
  • Since ZIKV, DENV and other flaviviruses including chikungunya, an arbovirus, co-circulate in the same regions, a positive result for one of these viruses does not preclude infection with the others. (healthresearch.org)
  • Another drawback of PRNT is that it has difficulties distinguishing the infecting virus (primary) in people with, or vaccinated against, a secondary infection. (healthresearch.org)
  • An extra step in our assay measures IgG antibodies by avidity testing, which determines the time-frame of infection, whether primary or secondary, and is quick and simple. (healthresearch.org)
  • For this reason, synthetic HPV particles such as virus-like particles (VLPs), PsVs and quasivirions (QVs) have been substituted for native HPV virions in studies investigating aspects of infection, transmission, immunogenicity, and viral structure [ 18 ]. (biomedcentral.com)
  • West Nile virus (WNV) is a re-emerging mosquito-borne viral infection. (kjccm.org)
  • Thus, the incidence of infection with these five viruses is generally lowest in industrialized and developed countries and highest in less-developed regions. (nationalacademies.org)
  • The immune system could play a crucial role in virus infection. (medsci.org)
  • The successful development and implementation to intervene prevention and treatment of virus infection over the past hundred years have had great advances on human and animal health. (medsci.org)
  • However, to this day, in the fight against virus infection, there is no real winner. (medsci.org)
  • The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
  • however, the virus can cross the placental barrier during the infection and is characterized by embryonic and fetal infection and death. (thenativeantigencompany.com)
  • Following infection, virus is shed in the secretions and excretions from the animal for approximately two weeks. (thenativeantigencompany.com)
  • The use of these vaccines induces antibody titres that can reduce clinical manifestations, but cannot prevent infection. (thenativeantigencompany.com)
  • Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France. (ox.ac.uk)
  • In contrast, at lower doses mice were able to clear the inoculum from the liver and spleen over a 3- to 4-week period, but persistence of the organism at other sites resulted in a chronic infection of between 2 and 16 months duration which was eventually lethal in all of the animals tested. (tropmedres.ac)
  • Neutralization of either tumor necrosis factor alpha or interleukin-12 but not granulocyte-macrophage colony-stimulating factor, also increased susceptibility to infection in vivo. (tropmedres.ac)
  • 33 Antigen detection assays are not available for MVEV, but have been used for JEV and Dengue fever virus. (mja.com.au)
  • Other tests can be used such as antibody-capture enzyme-linked immunosorbent assay (ELISA), antigen-capture detection tests, serum neutralization tests, electron microscopy, and virus isolation by cell culture. (unamhe.or.ug)
  • All nine laboratories performing NS1 antigen detection obtained the correct results. (who.int)
  • Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody-antigen immune complexes and immunoproteins or Fc receptor expressing immune effector cells. (frontiersin.org)
  • The Fc receptor-dependent function of antibody-dependent cellular phagocytosis (ADCP) provides mechanisms for clearance of virus and virus-infected cells, as well as for stimulation of downstream adaptive immune responses by facilitating antigen presentation, or by stimulating the secretion of inflammatory mediators. (frontiersin.org)
  • Some functions, such as neutralization, mainly depend on interaction of the Fv domain ( Figure 1A ) with antigen and are therefore predominantly Fc domain independent. (frontiersin.org)
  • Fc receptor-dependent antibody functions are also involved in activation of downstream adaptive immune responses by facilitating antigen presentation or by stimulating the secretion of inflammatory mediators ( 12 , 13 ). (frontiersin.org)
  • This was determined by indirect immunofluorescent (IF) staining of cultures using monoclonal antibody against a dengue-3 type-specific antigen. (microbiologyresearch.org)
  • Dengue-1 PI cultures stained with this antibody 3 days after superinfection with dengue-3 virus (m.o.i. of 2) had dengue-3 antigen in 0.1 to 1.0% of the cells. (microbiologyresearch.org)
  • Control cultures infected with dengue-3 at the same multiplicity contained dengue-3 antigen in greater than 90% of the cells. (microbiologyresearch.org)
  • A small population of cells was also found (about 1%) that contained type-specific antigen of both dengue virus types. (microbiologyresearch.org)
  • Progress in this arena, however, is being made with a new generation of merozoite antigen targets identified in recent years that exhibit relatively low levels of polymorphism and against which functional neutralizing antibodies can be raised by vaccination. (nature.com)
  • Developed by scientists at the New York State Department of Health Wadsworth Center and the University of Texas Medical Branch, the assay outperforms single antigen/antibody ZIKV IgM-Capture ELISA testing in overall sensitivity, specificity, positive predictive value and negative predictive value by detecting IgG-IgA-IgM antibodies to Zika Virus (ZIKV) and Dengue virus (DENV) serotypes 1-4. (healthresearch.org)
  • Our serologic assay overcomes these barriers by using an antibody-antigen sandwich formed on six Luminex beads with ZIKV envelope, ZIKV NS1, DENV1 NS1, DENV2 NS1, DENV3 NS1 and DENV4 NS1 conjugated to polyvalent IgG+IgA+IgM detector antibodies. (healthresearch.org)
  • Human leucocyte antigen ( HLA ) -DR plays a crucial role in the immune response against hepatitis B virus (HBV). (biomedcentral.com)
  • PsVs for Merkel cell polyoma virus (MCV) have been generated by co-transfection with the VP1 and VP2 genes of MCV strain 339 and a Green fluorescent protein (GFP) reporter plasmid of 293TT cells engineered to stably express the cDNA of Simian virus 40 (SV40) T antigen [ 3 ]. (biomedcentral.com)
  • This allows me to test the exciting hypothesis that a non-HIV antigen may be required to elicit HIV-bnAbs. (wrfseattle.org)
  • Dengue virus (DENV) is a flavivirus transmitted through the bite of an infected Aedes spp. (cdc.gov)
  • 10) Adding to the concern of indigenous dengue transmission is the recent establishment in the United States of another known dengue vector, Aedes albopictus, which was probably imported in shipments of tires from Asia. (cdc.gov)
  • The causative agents, enveloped single-strand RNA viruses from the genus Flavivirus with 4 serotypes, are transmitted by the bite of Aedes mosquitoes. (msdmanuals.com)
  • Aedes mosquitoes may acquire the virus when they feed on humans during this period. (msdmanuals.com)
  • In the Americas, Aedes aegypti is the mosquito vector that is the main source of dengue transmission. (paho.org)
  • This virus is an arbovirus and is transmitted among sloths, marsupials, primates, and birds through the mosquitoes Aedes serratus and Culex quinquefaciatus. (wikipedia.org)
  • tory testing to the Arbovirus Diagnostic Laboratory at the Over the next 20 years, several ZIKV isolates were Centers for Disease Control and Prevention (CDC, Fort obtained from Aedes spp. (folkhalsomyndigheten.se)
  • The Aedes mosquito, mainly Aedes aegypti and, to a lesser extent, Aedes albopictus, plays a crucial role in transmitting the dengue virus, which causes Dengue Hemorrhagic Fever. (tanzirislambritto.com)
  • Zika virus is primarily transmitted by Aedes aegypti mosquitoes, which are found throughout much of the region of the Americas, including parts of the United States ( 2 , 3 ). (cdc.gov)
  • Dengue is a disease transmitted by mosquitoes, with the primary vector being the Aedes Aegypti mosquito. (frontiersin.org)
  • Cultured Aedes albopictus cells (clone C6/36), persistently infected (PI) with dengue virus type 1 (dengue-1) were found resistant to superinfection with dengue virus type 3 (dengue-3). (microbiologyresearch.org)
  • Semliki Forest virus replication in cultured Aedes albopictus cells: studies on the establishment of persistence. (microbiologyresearch.org)
  • Morphogenesis of Sindbis virus in cultured Aedes albopictus cells. (microbiologyresearch.org)
  • Characteristics of Aedes albopictus cells persistently infected with dengue virus. (microbiologyresearch.org)
  • 125 countries includ- female mosquitoes, Aedes aegypti and Serum samples that tested positive ing Pakistan ( 2 , 3 ). (who.int)
  • The introduction of the naturally occurring wMel Wolbachia strain into Aedes aegypti mosquitoes has been shown to reduce the ability of the mosquitoes to transmit dengue and other viruses. (mvcac.org)
  • 1) Outbreaks of the more severe form of dengue, DHF, occurred in Cuba in 1981 (2) and in Venezuela in 1989. (cdc.gov)
  • 9) Outbreaks of indigenous dengue transmission occurred in Texas in 1980 and again in 1986. (cdc.gov)
  • Moreover, during the dry season there is a deceased chance of outbreaks which decreases the amount of midges this is because the amount of outbreaks is related to the number of human population that has not yet been exposed to this virus. (wikipedia.org)
  • In the Western Pacific Region, dengue outbreaks occur yearly in multiple countries, driven by a complex interplay of virus, vector and host biology, climatic and socioeconomic factors as well as international travel and trade. (who.int)
  • In 2013, outbreaks resulted in 44 098 dengue cases in the Lao People's Democratic Republic, 39 222 cases in Malaysia, 10 548 cases in New Caledonia and 22 170 cases in Singapore. (who.int)
  • Has the threat of Zika virus outbreaks come to an end? (rjppd.org)
  • There is currently no specific treatment for dengue, and vector control and vaccination are the only effective methods to prevent future outbreaks. (who.int)
  • In the Brazilian Amazon, oropouche is the second most frequent viral disease, after dengue fever. (wikipedia.org)
  • This leads to increased viral replication, a higher viral load, and a much more severe disease, resulting in DHF or even more severe dengue shock syndrome (DSS). (tanzirislambritto.com)
  • Isolation of an arbovirus, detection of specific antibody by plaque reduction neutralization assay or detection of nucleic acid by real-time RT-PCR in a clinical specimen would constitute firm evidence of viral association with illness and provide 'confirmed case' status. (canada.ca)
  • Finally, a summary of the immune biomarkers that have been reported for dengue and Zika viral infections are discussed which may be useful indicators for future anti-viral targets or predictors for disease severity. (frontiersin.org)
  • Like all plus-strand RNA viruses, the SARS-CoV-2 replication process within cells requires de novo production of viral RNA species, including single-strand (ss)RNA and double-strand (ds)RNA that can be sensed by cytosolic pattern recognition receptors (PRRs) subsequently activating antiviral pathways 7 . (nature.com)
  • ABSTRACT Dengue is one of the most important arthropod-borne viral diseases. (who.int)
  • Dengue virus is transmitted to was approved by the Ethics Committee borne viral diseases worldwide ( 1 ). (who.int)
  • PsV systems permit the continuous production of virus particles mimicking naturally occurring particles, and provide high-throughput systems for evaluating anti-viral agents and vaccine candidates. (biomedcentral.com)
  • In contrast to most bacteria, fungi, or parasites, viruses are completely dependent on the host cell for their replication, hijacking the cell's biochemical machinery through the actions of viral genome-encoded factors. (genetex.com)
  • Attachment of a virus to a specific receptor on a host cell leads to internalization and frequently the initiation of a new round of viral replication. (genetex.com)
  • Included in this viral pathogen list are the influenza viruses, dengue virus, Japanese encephalitis virus (JEV), hepatitis viruses (e.g. (genetex.com)
  • 11 It is also possible that prior immunisation with yellow fever virus or JEV vaccine may induce cross-reactive antibodies. (mja.com.au)
  • Here we describe a robust, objective, and scalable Fluorescence Reduction Neutralisation Test (FluoRNT) for yellow fever virus, relying on flow cytometric detection of cells infected with a fluorescent Venus reporter containing variant of the yellow fever vaccine strain 17D (YF-17D-Venus). (pasteur.fr)
  • One of the most effective prevention measures against YF is vaccination with the live, attenuated YF 17D substrain virus vaccine. (cdc.gov)
  • YF vaccine is recommended for persons aged ≥9 months who are traveling to or living in areas with risk for YF virus transmission [CDC 2010]. (cdc.gov)
  • In the United States, the current ACIP YF vaccine recommendations note that "[International Health Regulations] require revaccination at intervals of 10 years to boost antibody titer. (cdc.gov)
  • Antibodies are a key component of the human adaptive immune system, and the elicitation of antibodies has been correlated with vaccine efficacy in many diseases ( 1 ). (frontiersin.org)
  • Together, this information appraises the current understanding of both Zika and Dengue infections, providing insights for future vaccine design approaches against both viruses. (frontiersin.org)
  • The antibodies induced by one protein variant were shown to be qualitatively similar to responses induced by other vaccine platforms. (nature.com)
  • Anti-merozoite vaccine studies have long relied on the standardized in vitro assay of growth inhibition activity (GIA) 12 , whereby purified IgG antibodies are tested against parasites cultured in human red blood cells (RBC) in the absence of other cell types. (nature.com)
  • Classic examples of VAED are atypical measles and enhanced respiratory syncytial virus (RSV) occurring after administration of inactivated vaccine for these pathogens. (cov19longhaulfoundation.org)
  • The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. (biorxiv.org)
  • TWiV 1045: Less Lassa, CRISPR RNA viruses September 17, 2023 TWiV reviews a Lassa virus mRNA vaccine that confers protection against disease without inducing neutralizing antibodies, and a CRISPR-based method for engineering the genome of RNA viruses. (microbe.tv)
  • With this information, I hope to design a template for a vaccine that can teach our bodies to make HIV broadly neutralizing antibodies from scratch and protect us against HIV diversity. (wrfseattle.org)
  • An important person in the story is Max Theiler, who was Professor of Epidemiology and Public Health at Yale from 1964-67, and whose work on virus attenuation created the modern vaccine and earned him the Nobel Prize. (brewminate.com)
  • Blood samples were tested for antibodies against DENV. (cdc.gov)
  • The four dengue serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) circulate throughout the Americas, and in some countries simultaneously. (paho.org)
  • Laboratory testing with a rapid conducted at that time showed that 6.1% of the residents assay suggested that a dengue virus (DENV) was the caus- in nearby regions of Uganda had specifi c antibodies to ative agent. (folkhalsomyndigheten.se)
  • Some arboviruses, like dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV), have become fully adapted to urban cycles and no longer require NHPs, forest mosquitoes and a sylvatic cycle for their maintenance [ 7 ]. (biomedcentral.com)
  • Dengue virus (DENV) is an enveloped, single-stranded RNA virus belonging to the Flaviviridae family. (frontiersin.org)
  • Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate. (biomedcentral.com)
  • On 21 March 2023, the Ministry of Health (MoH) of the United Republic of Tanzania declared an outbreak of Marburg virus disease (MVD) in the country. (unamhe.or.ug)
  • WPV1 was detected in sewage samples from a site in the south region in May 2023 and one in the north region in June 2023, the first detections since February 2021 and March 2020, respectively. (cdc.gov)
  • TWiV 1047: Long COVID and avian flu in ferrets September 24, 2023 TWiV explains a study of postacute sequelae of COVID-19 at 2 years, and airborne transmission of human-isolated avian H3N8 influenza virus between ferrets. (microbe.tv)
  • Dengue-like epidemics occurred in Egypt and on Java in 1779, but these may actually have been caused by chikungunya virus. (cdc.gov)
  • For dengue, chikungunya, Zika and yellow fever viruses, sylvatic (forest) transmission cycles also exist in some regions and involve non-human primates and forest-dwelling mosquitoes. (biomedcentral.com)
  • Here we review the investigation methods and available data on sylvatic cycles involving non-human primates and dengue, chikungunya, Zika and yellow fever viruses in Africa, dengue viruses in Asia and yellow fever virus in the Americas. (biomedcentral.com)
  • These mosquitoes can also transmit dengue and chikungunya viruses ( 4 ). (cdc.gov)
  • All travelers to or residents of areas with ongoing Zika virus transmission should be advised to strictly follow steps to avoid mosquito bites because of the potential for exposure to Zika, dengue, and chikungunya viruses ( 6 ). (cdc.gov)
  • To prevent human-to-mosquito-to-human transmission, persons infected with Zika, dengue, or chikungunya virus should protect themselves from mosquito exposure during the first week of illness. (cdc.gov)
  • Overview of Arbovirus, Arenavirus, and Filovirus Infections Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes). (msdmanuals.com)
  • These mosquitoes are highly adaptive to the human environment, coupled with increasing urbanization and inadequate vector control, which has led to a surge in dengue transmission in urban and semi-urban settings. (tanzirislambritto.com)
  • Molecular screening of dengue virus in mosquitoes collected from field for early warning signals. (ncdc.gov.in)
  • Included within the series are papers on orbiviruses transmitted by Culicoides, lesser known viruses transmitted by mosquitoes including Cache Valley, Everglades, Jamestown Canyon, and LaCrosse, and recently discovered viruses transmitted by ticks including Bourbon, Heartland, Colorado tick fever, and Powassan. (mvcac.org)
  • 20 , 29 - 32 The use of PCR in conjunction with serological tests can increase the sensitivity of WNV diagnostic tests to 94% compared with 45% for serological tests alone. (mja.com.au)
  • Serological tests remain the mainstay of confirmatory diagnostic testing. (mja.com.au)
  • 29 , 37 Most reference laboratories have developed in-house MVEV serological tests that can detect total antibody by haemagglutination inhibition, IgG by immunofluorescence assays (IFA) or enzyme immunoassays (EIA), and IgM by IFA or EIA. (mja.com.au)
  • This first round of external quality assessment of dengue diagnostics was successfully conducted in national-level public health laboratories in the WHO Western Pacific Region, revealing good proficiency in both molecular and serological testing. (who.int)
  • Serological detection of total antibodies (IgM and IgG) directed towards Japanese Encephalitis (JE) virus by Hemagglutination Inhibition (HI) assay. (canada.ca)
  • This is an important distinction since currently serological assays only use ZIKV envelope or ZIKV NS1 antigens, as well as only one antibody, usually IgM, for their diagnostic assays. (healthresearch.org)
  • This increase may reflect increased incidence of dengue among travelers, increased number of travelers to areas in which dengue is endemic, increased awareness of the disease among physicians, or a combination of these factors. (cdc.gov)
  • Our findings are based on serologic testing in a cohort of short-term travelers from the Netherlands to dengue-endemic areas. (cdc.gov)
  • 1 countries to which dengue is endemic. (cdc.gov)
  • The second reason dengue should concern health care providers in this country is the potential for encountering cases of dengue among travelers arriving from dengue-endemic areas. (cdc.gov)
  • all the rest were travelers arriving from dengue-endemic areas. (cdc.gov)
  • Dengue is endemic to the tropical regions of the world in latitudes from about 35 ° north to 35 ° south. (msdmanuals.com)
  • 10 years living in areas where dengue is endemic. (msdmanuals.com)
  • An important difference to note, however, was that the Zika epidemic diffused in a shorter time span compared to the persisting feature of Dengue infections, which is endemic in many Asian countries. (frontiersin.org)
  • Zika virus (ZIKV) has been presumed to be endemic in Southeast Asia (SEA), with a low rate of human infections. (ox.ac.uk)
  • The early history of dengue is clouded by the similarity of its clinical picture to that of other febrile illnesses. (cdc.gov)
  • Prior to CDC, Dr. Ottendorfer's work experience included laboratory positions at the state public health reference laboratory at the Florida Department of Health for clinical laboratory testing and diagnosis of arboviral diseases. (cdc.gov)
  • 2004 . Clinical diagnosis and assessment of severity of confirmed dengue infections in Vietnamese children: is the world health organization classification system helpful? (ajtmh.org)
  • 1,2 Dengue presentation is broad and non-specific, which may confound clinical diagnosis. (who.int)
  • DHF is marked by the unique clinical features that differentiate it from common dengue fever. (tanzirislambritto.com)
  • Patient name and / or identifier (specimen reference number), date of birth, test(s) requested, collection date of specimen, date of on-set of symptoms, and clinical and travel history of patient. (canada.ca)
  • YF virus causes an estimated 200,000 cases of clinical disease and 30,000 deaths annually [WHO 1992]. (cdc.gov)
  • Updated guidelines include a new recommendation to offer serologic testing to asymptomatic pregnant women (women who do not report clinical illness consistent with Zika virus disease) who have traveled to areas with ongoing Zika virus transmission. (cdc.gov)
  • For pregnant women with clinical illness consistent with Zika virus disease,* testing is recommended during the first week of illness. (cdc.gov)
  • Despite revised clinical classifications of dengue infections by the World Health Organization, the wide spectrum of the manifestations of dengue illness continues to pose challenges in diagnosis and patient management for clinicians. (frontiersin.org)
  • Virus genomics as a clinical and epidemiological tool. (cdc.gov)
  • To confirm the dengue out-break from suspected clinical samples with the help of molecular diagnostic test (PCR/RT-PCR). (ncdc.gov.in)
  • Dengue endemicity was based on information from The Global Infectious Diseases and Epidemiology Online Network ( 14 ). (cdc.gov)
  • Dengue Branch and the Division of Vector Borne Infectious Diseases, Centers for Disease Control, CID, Fort Collins, CO. Duane J. Gubler, Sc.D and Edward B. Hayes, MD. (cdc.gov)
  • d WHO Collaborating Centre for Arbovirus Reference and Research (Dengue/Severe Dengue), Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. (who.int)
  • Download the latest version of GeneTex's Lateral Flow Antibody Pairs for Respiratory Infectious Diseases flyer. (genetex.com)
  • Robert H. Purcell is head of the Hepatitis Viruses Section of the Laboratory of Infectious Diseases, National Institute of Allergies and Infectious Diseases, National Institutes of Health, Bethesda, Maryland. (nationalacademies.org)
  • The serum neutralization test confirmed that 70 of the 173 ELISA-positive sera had neutralizing antibodies against TBEV. (biomedcentral.com)
  • Chunpeng Yang , Rui Gong , Natalia de Val , 2019: Development of Neutralizing Antibodies against Zika Virus Based on Its Envelope Protein Structure, Virologica Sinica, 34, 168-174. (virosin.org)
  • Xue-ling WU , Chun-tao ZHANG , Xiao-ke ZHU , You-chun WANG , 2010: Detection of HPV Types and Neutralizing Antibodies in Women with Genital Warts in Tianjin City, China, Virologica Sinica, 25, 8-17. (virosin.org)
  • The WNV RNA prevalence was 1.9% (95% CI, 1.4 to 2.9), while 14.3% (95% CI, 12.9 to 15.8) had WNV-neutralizing antibodies. (kjccm.org)
  • In animals, the pooled seroprevalence of anti-WNV IgM and IgG was 90.3% (95% CI, 84.3 to 94.6) and 3.5% (95% CI, 1.9 to 5.8), respectively, while 20.0% (95% CI, 12.9 to 21.4) had WNV-neutralizing antibodies. (kjccm.org)
  • I study the developmental pathway of HIV broadly neutralizing antibodies (bnAbs) in longitudinal samples of super-infected individuals. (wrfseattle.org)
  • These super defenses are called broadly neutralizing antibodies. (wrfseattle.org)
  • Positive and equivocal samples were confirmed for anti-ZIKV-neutralizing antibodies by virus neutralization tests. (ox.ac.uk)
  • However, cross-reactive antibodies remain problematic, and may complicate the ability to distinguish between MVEV and other flaviviruses. (mja.com.au)
  • Due to the cross-reactive nature of anti-flavivirus antibody, (Eg. (canada.ca)
  • It is transmitted by the bite of a mosquito infected with one of the four serotypes of dengue virus. (paho.org)
  • We determined the frequency of different serotypes of dengue virus to highlight its hyperendemicity in Rawalpindi, Pakistan. (who.int)
  • In 2%-3% of patients, dengue hemorrhagic fever develops ( 5 ). (cdc.gov)
  • Although the incidence of hemorrhagic dengue in United States travelers abroad is low,(13,15) clinicians in this country may encounter severe cases of dengue, particularly among immigrants from areas with a high incidence of DHF. (cdc.gov)
  • 17) Hemorrhagic manifestations, including gastrointestinal hemorrhage, were described during dengue epidemics in Texas and Louisiana in 1922. (cdc.gov)
  • 14,18,19) Nevertheless through the first half of the 20th century, dengue was generally described as a self-limited, nonfatal febrile illness, with occasional hemorrhagic manifestations such as petechiae, epistaxis, gingival bleeding and menorrhagia, that only rarely resulted in more severe or fatal outcomes. (cdc.gov)
  • Dengue can also cause potentially fatal hemorrhagic fever with a bleeding tendency and shock. (msdmanuals.com)
  • Treatment is symptomatic and, for dengue hemorrhagic fever, includes meticulously adjusted intravascular volume replacement. (msdmanuals.com)
  • Dengue Hemorrhagic Fever (DHF) is an acute and potentially lethal complication of dengue fever, a tropical disease caused by the dengue virus. (tanzirislambritto.com)
  • What Causes Dengue Hemorrhagic Fever? (tanzirislambritto.com)
  • Dengue hemorrhagic fever - Do we know its cause? (microbiologyresearch.org)
  • We assessed predominantly pediatric patients in Vietnam with dengue and other febrile illness 3 months after acute illness. (researchgate.net)
  • and identify Zika virus laboratory testing algorithms and resources. (cdc.gov)
  • Zika virus, yellow fever, and COVID-19). (cdc.gov)
  • Zika virus (ZIKV), a mosquito-borne transplacentally transmissible flavivirus, is an enveloped virus with an ~10.8 kb plus-strand RNA genome that can cause neurological disease. (mdpi.com)
  • Zika virus (ZIKV) is a mosquito-borne fl avivirus fi rst studies in the absence of epidemics ( 6 - 8 ). (folkhalsomyndigheten.se)
  • The Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) belonging to the Flavivirus genus and the Flaviviridae family. (rjppd.org)
  • Zika virus in the Americas: Early epidemiological and genetic findings:345-349. (rjppd.org)
  • History and Emergence of Zika Virus. (rjppd.org)
  • Zika virus in Asia. (rjppd.org)
  • ABSTRACT Following the WHO declaration on 1 February 2016 of a Public Health Emergency of International Concern (PHEIC) with regard to clusters of microcephaly and neurological disorders potentially associated with Zika virus, the WHO Regional Office for the Eastern Mediterranean conducted three rounds of emergency meetings to address enhancing preparedness actions in the Region. (who.int)
  • Zika virus like other vector-borne diseases poses a particular challenge to the countries because of their complex nature which requires multidisciplinary competencies and strong rapid interaction among committed sectors. (who.int)
  • CDC has updated its interim guidelines for U.S. health care providers caring for pregnant women during a Zika virus outbreak ( 1 ). (cdc.gov)
  • This update also expands guidance to women who reside in areas with ongoing Zika virus transmission, and includes recommendations for screening, testing, and management of pregnant women and recommendations for counseling women of reproductive age (15-44 years). (cdc.gov)
  • For asymptomatic pregnant women residing in areas with ongoing Zika virus transmission, testing is recommended at the initiation of prenatal care with follow-up testing mid-second trimester. (cdc.gov)
  • Local health officials should determine when to implement testing of asymptomatic pregnant women based on information about levels of Zika virus transmission and laboratory capacity. (cdc.gov)
  • The Zika virus outbreak continues to spread ( http://www.cdc.gov/zika/geo/index.html ), with ongoing Zika virus transmission recently reported in U.S. territories. (cdc.gov)
  • 181B potentially associated with Zika virus (ZIKV) has highlighted the urgent need to identify individuals infected with ZIKV. (who.int)
  • Taking advantage of this expertise we also developed a diagnostic test for Zika virus that does not require sophisticated equipment or extensive laboratory personnel training. (utmb.edu)
  • These releases were undertaken under operational conditions with the aim of rapidly scaling the intervention in response to the Zika virus crisis. (mvcac.org)
  • The Zika virus (ZIKV) is one of the most infamous mosquito-borne flavivirus on recent memory due to its potential association with high mortality rates in fetuses, microcephaly and neurological impairments in neonates, and autoimmune disorders. (asme.org)
  • Low Zika Virus Seroprevalence in Vientiane, Laos, 2003-2015. (ox.ac.uk)
  • Zika virus seroprevalence observed in the studied blood donors was low, 4.5% in 2003-2004 with an increase in 2015 to 9.9% (P = 0.002), possibly reflecting the increase of ZIKV incident cases reported over this period. (ox.ac.uk)
  • Notre objectif est de décrire le schéma de présentation des patients atteints de la maladie qui ont été pris en charge lors de l'épidémie de 2020 qui s'est produite dans l'État du Delta. (bvsalud.org)
  • 38 Neutralisation tests or an epitope-blocking ELISA can help identify MVEV-specific antibodies. (mja.com.au)
  • 2015 we analysed the serum samples of 140 patients with a suspicion of dengue, using ELISA and multiplex polymerase chain reaction. (who.int)
  • Les échantillons de sérum de 140 patients susceptibles d'avoir contracté le virus de la dengue ont été analysés entre mai et octobre 2015 à l'aide du test ELISA et de l'amplification en chaîne par polymérase multiplexe. (who.int)
  • A pregnant woman can pass the dengue virus to her fetus during pregnancy or around the time of birth, although the rate of vertical transmission appears low (see World Health Organization [WHO]: Dengue and severe dengue ). (msdmanuals.com)
  • The illness can evolve to severe dengue, characterized by shock, respiratory distress, severe bleeding, and/or serious organ impairment. (paho.org)
  • The disease can evolve into severe dengue, characterized by shock, shortness of breath, severe bleeding and / or complications in the organs. (paho.org)
  • Illness caused by Marburg virus begins abruptly, with high fever, severe headache, and severe malaise. (unamhe.or.ug)
  • The majority (~75%) of infections in humans are asymptomatic, but a small proportion of symptomatic patients develops severe dengue characterized by rapid progression into shock, severe bleeding and/or multiorgan impairment, which leads to death if unattended or mismanaged. (who.int)
  • It causes high fever and the typical flu-like symptoms seen in dengue and leads to severe bleeding, blood plasma leakage, and low platelet count. (tanzirislambritto.com)
  • Instead, they aid the virus entering host cells, enhancing its reproduction ability and leading to severe disease. (tanzirislambritto.com)
  • The HI assay is used to measure the level of antibodies in a patient's serum that will prevent the agglutination of susceptible erythrocytes by inactivated antigens that are able to attach to the erythrocyte receptors on red blood cells. (canada.ca)
  • FluoRNT: A robust, efficient assay for the detection of neutralising antibodies against yellow fever virus 17D. (pasteur.fr)
  • One of the earliest, if not the first, dengue epidemics described in the medical literature occurred in Philadelphia in 1780. (cdc.gov)
  • 5-7) Dengue epidemics were reported in various parts of the south- eastern United States through the 19th and 20th centuries, (6) most recently in Louisiana in 1945. (cdc.gov)
  • 7) Dengue or dengue-like epidemics were reported through- out the 19th and early 20th centuries in the Americas, southern Europe, North Africa, the Middle East, Asia and Australia and on various islands in the Indian Ocean, South and Central Pacific and the Caribbean. (cdc.gov)
  • 7) Deaths occurred during dengue epidemics in Australia in 1897 and in Greece in 1928, when over 1000 deaths were reported. (cdc.gov)
  • Urban transmission cycles of arboviruses in densely populated tropical regions can result in explosive epidemics and pandemics, although there can also be low levels of transmission only sufficient to maintain the viruses in the population. (biomedcentral.com)
  • Hundreds of thousands of cases of dengue and DHF are reported each year in tropical regions of the Americas, Africa, Asia and Oceania. (cdc.gov)
  • From 1980 through 1987, 879 632 cases of dengue were reported to the Pan American Health Organization from countries in the American region. (cdc.gov)
  • 13-15) From 1980 through 1989, 1457 suspected and 276 confirmed cases of dengue in the continental United States and Hawaii were reported to the Centers for Disease Control. (cdc.gov)
  • 50-100 million cases of dengue fever brate hosts of dengue virus in nature cessed by multiplex polymerase chain and 500 000 of dengue haemorrhagic are humans and several species of Asian reaction (PCR) in which the presence fever (DHF) reported annually ( 4 ). (who.int)
  • Since the initial outbreak of the disease, it has been recognized that the sensitivities and specificities for current ZIKV testing algorithms have shortcomings. (healthresearch.org)
  • Of primary concern is the risk of dengue transmission within the continental United States. (cdc.gov)
  • Approximately 500 million people in the Americas are today at risk of dengue. (paho.org)
  • is the vector mosquito for dengue and is widely distributed in the Americas. (paho.org)
  • Only Canada and continental Chile are free from dengue and its vector. (paho.org)
  • The oropouche virus has evolved to an urban cycle infecting humans though midges as its main transporting vector. (wikipedia.org)
  • To sum up, the cause of DHF is multi-factorial, involving not only the dengue virus and its serotypes but also the human immune response, the vector mosquito species, and various ecological factors. (tanzirislambritto.com)
  • Although it has been sought, arthropod-borne or other vector-mediated transmission of the blood-borne hepatitis viruses has not been found. (nationalacademies.org)
  • This review discusses similarities between Dengue and Zika infections, comparing their disease transmissions and vectors involved, and both the innate and adaptive immune responses in these infections. (frontiersin.org)
  • Consideration of the genetic identity of both the Dengue and Zika flaviviruses as well as the cross-reactivity of relevant T cells along with the actions of CD4+ cytotoxic cells in these infections are also presented. (frontiersin.org)
  • The attempts to treat virus infections occur even earlier than there was an understanding of the concept of a virus as an independent entity. (medsci.org)
  • Yellow Fever, Dengue, Powassan, etc.) detection of total anti-JE virus specific antibody in a single serum sample is indicative of past or present exposure to this agent, or a related agent from the same virus genus. (canada.ca)
  • Dengue fever usually results in abrupt onset of high fever, headache, myalgias, arthralgias, and generalized lymphadenopathy, followed by a rash that appears with a recurrent fever after an afebrile period. (msdmanuals.com)
  • Oropouche fever is caused by a specific arbovirus, the Oropouche virus (OROV), of the Bunyaviridae family. (wikipedia.org)
  • The oropouche virus is an emerging infectious agent that causes the illness oropouche fever. (wikipedia.org)
  • Oropouche fever is caused by the oropouche virus (OROV) that belongs to the Peribunyaviridae family of arboviruses. (wikipedia.org)
  • Identification of a novel lineage of Crimean-Congo haemorrhagic fever virus in dromedary camels, United Arab Emirates. (cdc.gov)
  • From 1981 through 1986, 796 386 cases of DHF and 9774 deaths caused by dengue were reported to the World Health Organization (WHO) from countries in Southeast Asia. (cdc.gov)
  • The objective of this programme was to assess dengue diagnostic proficiency among national-level public health laboratories in the World Health Organization (WHO) Western Pacific Region. (who.int)
  • Dengue-like illness occurred in 5 of the 14 travelers who seroconverted. (cdc.gov)
  • This occurs when two genetically related viruses infect the same cell at the same time forming a progeny virus and this virus holds various components of genetic L, M and S segments from the two parental viruses. (wikipedia.org)
  • To study the genetic variation in dengue virus. (ncdc.gov.in)
  • Pseudoviruses (PsV) are synthetic viruses that can include genetic material such as DNA and RNA, and are closely related to the structures and characteristics of its native viruses, but lack characteristics shown in the authentic viruses such as capability for replication [ 1 ]. (biomedcentral.com)
  • Deoxyribonucleic acid that makes up the genetic material of viruses. (lookformedical.com)
  • Viruses whose genetic material is RNA. (lookformedical.com)
  • Porcine parvovirus 5 (PPV5) is still not classified in the ICTV taxonomy proposal, but genetic analysis showed that this virus is most closely related to PPV4. (thenativeantigencompany.com)
  • 46 There are numerous reports of immunotherapy for WNV encephalitis in Israel and the United States with WNV-specific intravenous immunoglobulin (Omr-IgG-am, Omrix Biopharmaceuticals, Tel Aviv, Israel) obtained from donors with high titres of WNV antibodies. (mja.com.au)
  • It accurately measures neutralising antibody titres in human serum samples within as little as 24 h. (pasteur.fr)
  • Further comprehensive diagnostic testing for dengue virus and other priority pathogens in the Region will be assessed during future rounds. (who.int)
  • Fc receptor-dependent antibody functions are important components of the immune response that provide mechanisms for clearance of infected host cells, immune complexes, or opsonized pathogens. (frontiersin.org)
  • Instead, they form complexes with the virus that are more readily taken up by cells involved in the immune response. (tanzirislambritto.com)
  • These Fc receptor-dependent antibody functions provide a direct link between the innate and adaptive immune systems by combining the potent antiviral activity of innate effector cells with the diversity and specificity of the adaptive humoral response. (frontiersin.org)
  • Receptors for the Fc region of IgG (Fc gamma Rs) are members of the Ig superfamily that function in the activation or inhibition of immune responses such as degranulation, phagocytosis, ADCC (antibody-dependent cellular toxicity), cytokine release, and B cell proliferation (1‑3). (novusbio.com)
  • Plus-strand RNA viruses have evolved numerous ways to limit or block these cellular immune pathways. (nature.com)
  • My job is to learn from the patients' samples what is required to induce our immune system to make these super-effective antibodies. (wrfseattle.org)
  • Reference Dengue is a mosquito-borne disease caused by a flavivirus. (msdmanuals.com)
  • Dengue is transmitted by the bite of an infected mosquito. (paho.org)
  • Murray Valley encephalitis virus (MVEV) is a mosquito-borne virus that is found across Australia, Papua New Guinea and Irian Jaya. (mja.com.au)
  • Zika: the origin and spread of a mosquito-borne virus. (rjppd.org)
  • A mosquito-borne encephalitis caused by the Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE) occurring throughout Eastern Asia and Australia. (curehunter.com)
  • The tests' validation studies will be performed in collaboration with the Texas Department of State Health Services and the Harris County Mosquito Control District. (utmb.edu)
  • more recently, dengue incidence has increased in Central and South America. (msdmanuals.com)
  • Dengue incidence has increased in the Americas over the past four decades, from 1.5 million cumulative cases in the 1980s to 16,2 million in the decade 2010-2019. (paho.org)
  • 28 Indeed, by the time neurological symptoms develop, PCR testing of serum or CSF often returns a negative result. (mja.com.au)
  • To demonstrate seroconversion, both acute and convalescent samples must be tested in parallel. (canada.ca)
  • Referred and suspected cases of HBV and HCV from different hospitals of Delhi and adjoining areas were confirmed by molecular diagnostic test (PCR/RT-PCR)targeting surface gene, core gene and 5'UTR gene region. (ncdc.gov.in)
  • To indicate the dengue virus type and genotype of the Dengue out-break with the help of molecular characterization and genotyping of dengue virus based on gene sequencing. (ncdc.gov.in)
  • Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response. (lookformedical.com)
  • 26. Mohammed H, Tomashek KM, Stramer SL, Hunsperger E. Prevalence of anti-dengue immunoglobulin G antibodies among American Red Cross blood donors in Puerto Rico, 2006. (rjppd.org)
  • As stated by Kuno & Chang [ 15 ], "The three commonly used data for identifying vertebrate reservoirs for arboviruses have been (i) virus isolation from suspected animals, (ii) relatively high antibody prevalence in the animals captured in the field and (iii) demonstration of viraemia (of higher virus titre and duration) in the suspected animals typically obtained under laboratory conditions" [ 15 ]. (biomedcentral.com)
  • Nineteen national-level public health laboratories performed routine dengue diagnostic assays on a proficiency testing panel consisting of two modules: one containing commercial serum samples spiked with cultured dengue viruses for the detection of nucleic acid and non-structural protein 1 (NS1) (Module A) and one containing human serum samples for the detection of anti-dengue virus antibodies (Module B). A review of logistics arrangements was also conducted. (who.int)
  • Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses. (rjppd.org)
  • Identification of dengue viruses from the Caribbean by plaque-reduction neutralization test. (microbiologyresearch.org)
  • this population is not likely to qualify for access to confirmatory plaque reduction neutralization testing (PRNT) and therefore the virus could go undetected. (healthresearch.org)
  • e WHO Collaborating Centre for Reference and Research on Tropical and Emerging Virus Diseases, Nagasaki University, Nagasaki, Japan. (who.int)
  • Other viruses, principally from the families Arenaviridae, Bunyaviridae, Flaviviridae, Filoviridae, and Herpesviridae , also cause hepatitis as part of systemic diseases, but these are generally not grouped with the hepatitis viruses. (nationalacademies.org)
  • Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
  • A general term for diseases produced by viruses. (lookformedical.com)
  • Blood-stage vaccines seek to induce antibodies against the merozoite form of the parasite that invades erythrocytes 2 , and could complement pre-erythrocytic immunity afforded by RTS,S/AS01, protect against disease severity and/or reduce transmission by accelerating the control and clearance of blood-stage parasitemia. (nature.com)
  • Our group has developed sensitive and specific field-applicable diagnostic tests for multiple infectious agents, principally parasites ( Leishmania , Cryptosporidium , Giardia , Entamoeba , Plasmodium and Trypanosoma cruzi ). (utmb.edu)
  • I built tools to study this virus and contributed to a diagnostic test during the first year of my M.Sc. (wrfseattle.org)
  • Depuis 2017, le Nigéria est confronté à des flambées annuelles de la maladie malgré la disponibilité d'un vaccin sûr et efficace qui a été introduit dans le Programme élargi de vaccination du pays en 2004. (bvsalud.org)
  • PFOA, PFOS, PFHxS, and PFNA serum concentrations prior to vaccination were not associated with differences in peak antibody response after vaccination or with differences in decline of antibodies over time after vaccination. (cdc.gov)
  • The potential for vaccination against SARS-CoV-2 to be associated with disease enhancement is of theoretical concern, given similar observations with other respiratory viruses in general, and in animal models of highly pathogenic coronaviruses in particular [14] . (cov19longhaulfoundation.org)
  • It has been observed that new mutations in the capsid protein can modify antigenic properties, and may reduce the cross neutralization ability of sera raised against strains commonly used in commercial vaccines. (thenativeantigencompany.com)
  • MÉTHODES: Les données ont été recueillies à partir des notes de cas de 27 patients pris en charge pour la maladie, à l'aide d'un proforma décrivant leurs symptômes, signes, mesures de traitement et résultats. (bvsalud.org)
  • However, pleurodynia most commonly affects adults infected with the virus, with fewer than 10% of cases occurring in patients younger than 20 years. (medscape.com)
  • 李红霞 , 孟小林* , 徐进平 , 王 健 , 鲁 伟 , 曹 旭 , 2004: Expression of Recombinant Envelope Proteins VP19 and VP28 of WSSV and Preparation of Neutralizing Antibody, Virologica Sinica, 19, 587-590. (virosin.org)
  • Proteins found in any species of virus. (lookformedical.com)
  • Two nonstructural proteins, NS1 and NS2, operate in the replication of the virus, particularly for DNA replication. (thenativeantigencompany.com)
  • SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. (nature.com)
  • Each belongs to an entirely different family of viruses, and they have very little in common except the target organ they affect, the liver, and a certain degree of shared epidemiology. (nationalacademies.org)
  • Changes in human ecology and behavior have had discernable effects on the epidemiology of the hepatitis viruses in different ways and to different degrees. (nationalacademies.org)
  • This paper is the introduction to Special Collection of 10 papers on the epidemiology and ecology of emerging and lesser-known viruses of public and veterinary importance within the United States. (mvcac.org)
  • Dengue prevention and control must be intersectoral and involve the family and the community. (paho.org)
  • PAHO/WHO provides advice and technical support for dengue prevention and control based on a regional strategy adopted by PAHO / WHO member States in 2016, called the " Strategy for arboviral disease prevention and control " (CD55.R6). (paho.org)