- Chromosomal-mediated AmpC β-lactamases represent a new threat, since they confer resistance to 7-alpha-methoxy-cephalosporins (cephamycins) such as cefoxitin or cefotetan but are not affected by commercially available β-lactamase inhibitors, and can, in strains with loss of outer membrane porins, provide resistance to carbapenems. (wikipedia.org)
- TEM-3, TEM-4, and SHV-2 ) which confer resistance to expanded-spectrum (extended-spectrum) cephalosporins. (wikipedia.org)
- When the strain produces class A -lacta- cephamycinases, which confer resistance to expanded- mases, including TEM- or SHV-derived ESBLs, or CTX- spectrum cephalosporins (22,23), and no CTX-M-type - M-type enzymes, the color of a disk containing ben- lactamase producer has been isolated from animals. (cdc.gov)
- Thus ESBLs confer multi-resistance to these antibiotics and related oxyimino-beta lactams. (wikipedia.org)
- 1 Since then, extended-spectrum β-lactamases (ESBLs) have become an increasingly important resistance mechanism among Enterobacteriaceae worldwide. (ajlmonline.org)
- Among Gram-negative bacteria, the emergence of resistance to extended-spectrum cephalosporins has been a major concern. (wikipedia.org)
- Beta-lactamases (β-lactamases) are enzymes (EC 3.5.2.6) produced by bacteria that provide multi-resistance to beta-lactam antibiotics such as penicillins, cephalosporins, cephamycins, monobactams and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. (wikipedia.org)
- Among Gram-negative bacteria, the emergence of resistance to extended-spectrum cephalosporins has been a major concern. (wikipedia.org)
- Chromosomal-mediated AmpC β-lactamases represent a new threat, since they confer resistance to 7-alpha-methoxy-cephalosporins (cephamycins) such as cefoxitin or cefotetan but are not affected by commercially available β-lactamase inhibitors, and can, in strains with loss of outer membrane porins, provide resistance to carbapenems. (wikipedia.org)
- TEM-3, TEM-4, and SHV-2 ) which confer resistance to expanded-spectrum (extended-spectrum) cephalosporins. (wikipedia.org)
- These findings suggest that CTX-M-2 metallo--lactamase, which show resistance to carbapen- producers might have originated from cattle through the ems and cephamycins as well as various expanded-spec- use of cephalosporins such as ceftiofur and that cattle trum cephalosporins, have been identified in Japan (15), could be a reservoir of CTX-M-2-producing E. coli . (cdc.gov)
- When the strain produces class A -lacta- cephamycinases, which confer resistance to expanded- mases, including TEM- or SHV-derived ESBLs, or CTX- spectrum cephalosporins (22,23), and no CTX-M-type - M-type enzymes, the color of a disk containing ben- lactamase producer has been isolated from animals. (cdc.gov)
- Beta-lactamases are enzymes ( EC 3.5.2.6 ) produced by some bacteria and are responsible for their resistance to beta-lactam antibiotics like penicillins , cephalosporins , cephamycins and carbapenems . (wikidoc.org)
- Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. (wikipedia.org)
- Given that A. baumannii is associated with higher mortality and greater antibiotic resistance, being able to differentiate between the different species with the A. calcoaceticus-A. baumannii complex is important. (medscape.com)
- A few years later, resistance appeared in bacterial species not naturally producing AmpC enzymes (K. pneumoniae, Salmonella spp. (wikipedia.org)