• This drug can be given orally, by nasal spray that's absorbed through the mucous membranes, or by S.C. or l.V. injection. (health-care-clinic.org)
  • The use of Desmopressin Acetate Nasal Spray in patients with an established diagnosis will result in a reduction in urinary output with increase in urine osmolality and a decrease in plasma osmolality This will allow the resumption of a more normal life-style with decrease in urinary frequency and nocturia . (wikidoc.org)
  • The nasal spray pump can only deliver doses of 0.1 mL (10 mcg) or multiples of 0.1 mL. (wikidoc.org)
  • Discard Desmopressin Acetate Nasal Spray after 50 sprays since the amount delivered thereafter per spray may be substantially less than 10 mcg of drug. (wikidoc.org)
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  • The nasal spray is absorbed through the nasal mucosa and enters the bloodstream. (rawoodfoundation.org)
  • Similar to the nasal spray, the nasal solution is also administered through the nostrils. (rawoodfoundation.org)
  • It's usually used for similar indications as the nasal spray, and the liquid form allows for controlled dosing. (rawoodfoundation.org)
  • Desmopressin is administered as a nasal spray, as oral tablets or through injection. (icloudhospital.com)
  • Desmopressin can be administered orally in tablet form, as a nasal spray, or through injection. (mrmed.in)
  • The nasal spray is administered by spraying into the nostrils, alternating nostrils with each dose. (mrmed.in)
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  • The present invention relates generally to vitamin B12 nasal spray compositions and methods of using the same in the treatment of vitamin B12 deficiency and various disorders that are related to such deficiency. (justia.com)
  • In particular embodiments, the present invention is directed to treatment methods comprising intranasal administration of a cobalamin composition according to a particular dosing and frequency schedule and to a preservative-free nasal spray composition comprising a cobalamin compound useful in the practice of such treatment methods. (justia.com)
  • Among these are parenterally, including intramuscular and subcutaneous injection, orally as a component of a tablet or solution, and nasally, as a component of a nasal spray or gel. (justia.com)
  • For example, NASCOBAL nasal spray solution containing 0.5% by weight cyanocobalamin is administered in one nostril once weekly in a dose of 500 μg (i.e., 500 μg cyanocobalamin per 0.1 mL actuation of the spray bottle pump). (justia.com)
  • FOR IMMEDIATE RELEASE - Parsippany, NJ - August 5, 2020- Ferring Pharmaceuticals US is voluntarily recalling all lots on the market of DDAVP® Nasal Spray 10 mcg/0.1mL, Desmopressin Acetate Nasal Spray 10 mcg/0.1mL, and STIMATE® Nasal Spray 1.5 mg/mL listed in the table below to the consumer. (ferringusa.com)
  • Do not use MINIRIN Nasal Spray to treat any other complaints unless your doctor tells you to do so. (urinaryhealthtalk.com)
  • Avadel Pharmaceuticals plc has announced the launch of desmopressin acetate , an emulsified microdose nasal spray. (urinaryhealthtalk.com)
  • The nasal spray is a proprietary emulsified microdose of desmopressin combined with a permeation enhancer that increases the transport of desmopressin across the nasal mucosa. (urinaryhealthtalk.com)
  • Fluticasone nasal spray ( Veramyst , GlaxoSmithKline) was approved for the treatment of seasonal and year-round allergy symptoms in adults and children aged ≥2 years. (formularywatch.com)
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  • These include poor intranasal absorption, nasal congestion and blockage, nasal discharge, atrophy of nasal mucosa, and severe atrophic rhinitis. (druglib.com)
  • Although maintenance therapy with vitamin B 12 nasal compositions has proven generally effective, those undergoing such therapy may experience some irritation of the nasal mucosa and discomfort due, in part, to the high dosage of the cobalamin compound typically administered as well as preservatives and other additives often present in these compositions. (justia.com)
  • Most cases of gestational DI can be treated with desmopressin (DDAVP), but not vasopressin. (wikipedia.org)
  • For central diabetes insipidus, synthetic vasopressin or desmopressin (a synthetic form of vasopressin) can be prescribed to help regulate water balance. (rawoodfoundation.org)
  • Desmopressin is a medication that mimics the action of the hormone vasopressin in the body. (mrmed.in)
  • Desmopressin is a synthetic analog of the natural antidiuretic hormone arginine vasopressin (ADH), which has increased antidiuretic activity, prolonged duration of action, decreased pressor actions, and fewer side effects than the natural hormone. (veteriankey.com)
  • As an alternative to water deprivation testing, a simpler and more practical method of diagnosis is evaluation of the clinical response to a closely monitored therapeutic trial with desmopressin (DDAVP, Stimate, Minirin). (veteriankey.com)
  • This is one of the more common forms of desmopressin. (rawoodfoundation.org)
  • When comparing the cost of the proprietary forms of desmopressin, the tablet form is a more cost-prohibitive alternative compared with the conjunctival or subcutaneous routes of administration. (veteriankey.com)
  • Typically, many DI symptoms are treated with a man-made hormone called desmopressin (DDAVP, Minirin, et al. (icloudhospital.com)
  • Patients with nasal congestion and blockage have often responded well to intranasal Desmopressin Acetate. (wikidoc.org)
  • The cost of daily oral desmopressin in animals is roughly 2.5 times that of conjunctival drops and roughly 6 times that of subcutaneous injections of desmopressin. (veteriankey.com)
  • Desmopressin is available in tablet form, which can be taken orally. (rawoodfoundation.org)
  • Instruct the client in the administration of medications as prescribed (DDAVP may be administered by injection, intranasally, or orally). (surenapps.com)
  • Desmopressin acetate is also available as an intranasal preparation. (druglib.com)
  • Continued response to intranasal desmopressin acetate can be monitored by urine volume and osmolality . (wikidoc.org)
  • Desmopressin Acetate is also available as a solution for injection when the intranasal route may be compromised. (wikidoc.org)
  • You'll usually start taking the anti-androgen tablets before your first injection or implant. (crworkshops.com)
  • The proprietary and generic oral preparations of desmopressin are available both as a sublingual dissolve melt tablet and as 0.1 mg and 0.2 mg tablets. (veteriankey.com)
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  • Desmopressin acetate is effective for 8 to 20 hours, depending on the dosage. (health-care-clinic.org)
  • Desmopressin Acetate Injection 4 mcg/mL dosage must be determined for each patient and adjusted according to the pattern of response. (druglib.com)
  • For patients with adipsia or are newly diagnosed, routine blood sodium testing may be required to ensure sodium levels are within a safe range and to reach a proper dosage of desmopressin. (rawoodfoundation.org)
  • Desmopressin Acetate Injection 4 mcg/mL is administered as an intravenous infusion at a dose of 0.3 mcg desmopressin acetate/kg body weight diluted in sterile physiological saline and infused slowly over 15 to 30 minutes. (druglib.com)
  • About 1/4 to 1/3 of patients can be controlled by a single daily dose of Desmopressin Acetate administered intranasally. (wikidoc.org)
  • For example, the prescribed initial therapeutic dose is generally from about 100 μg to about 1000 μg, and is most often administered by intramuscular injection. (justia.com)
  • Typically, such therapy includes relatively infrequent, high dose nasal administration of a cobalamin composition. (justia.com)
  • It will take about 2 hours for you to receive your entire dose of infliximab injection. (oncology-drugs.net)
  • This formulation is administered subcutaneously or by direct intravenous injection. (druglib.com)
  • Similar to the case for desmopressin, a single intravenous tail injection of CPT into Sprague-Dawley rats reduced urine output and increased urinary osmolality. (bvsalud.org)
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  • Advice regarding Desmopressin is to always consult with a healthcare professional before starting or making any changes to your medication regimen. (mrmed.in)
  • I have been on this medication since the early eighties and the nasal spay is much better than the injections that I was originally given. (webmd.com)
  • A medication that's commonly prescribed to take care of frequent urination is desmopressin acetate. (acsp.ac.th)
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  • Desmopressin Acetate Injection 4 mcg/mL is indicated as antidiuretic replacement therapy in the management of central (cranial) diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. (druglib.com)
  • Desmopressin acetate is ineffective for the treatment of nephrogenic diabetes insipidus. (druglib.com)
  • Desmopressin (nasal) is a hemostatic and metabolic agent that is FDA approved for the treatment of central cranial diabetes insipidus , temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. (wikidoc.org)
  • Can desmopressin be used for the treatment of diabetes insipidus in pregnancy? (mrmed.in)
  • The use of desmopressin for diabetes insipidus during pregnancy requires careful evaluation by a healthcare provider. (mrmed.in)
  • In the US, Desmopressin (desmopressin systemic) is a member of the drug class antidiuretic hormones and is used to treat Diabetes Insipidus , Hemophilia A , Nocturia , Primary Nocturnal Enuresis and von Willebrand Disease . (drugs.com)
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  • In central and gestational DI, treatment is with desmopressin. (wikipedia.org)
  • Treatment with desmopressin may lead to water intoxication. (wikipedia.org)
  • Desmopressin acetate is not indicated for the treatment of hemophilia A with factor VIII coagulant activity levels equal to or less than 5%, or for the treatment of hemophilia B, or in patients who have factor VIII antibodies. (druglib.com)
  • Desmopressin acetate is not indicated for the treatment of severe classic von Willebrand's disease (Type I) and when there is evidence of an abnormal molecular form of factor VIII antigen. (druglib.com)
  • Further research examining the physiological reasoning behind this gender-specific dosing for desmopressin and the optimal recommended treatment duration of desmopressin for those over 65 is needed. (bvsalud.org)
  • Among the 40 small molecules are two previously unapproved marketed drugs: calcium gluconate injection for symptomatic hypocalcemia (original approval 1941) 1 and ascorbic acid injection (Ascor) for the short-term treatment of scurvy (initial approval 1947). (mhmedical.com)
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  • FDA has granted full approval for cytarabine liposome injection ( DepoCyt , Enzon) for the treatment of patients with lymphomatous meningitis. (formularywatch.com)
  • In rare cases, however, an abnormality in the thirst mechanism causes gestational DI, and desmopressin should not be used. (wikipedia.org)
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  • Bleeding time and factor VIII coagulant activity, ristocetin cofactor activity, and von Willebrand factor antigen should be checked during administration of desmopressin acetate to ensure that adequate levels are being achieved. (druglib.com)
  • This agent was previously approved to treat and prevent bleeding in patients with hemophilia A and to treat spontaneous and traumatic bleeding in patients with severe von Willebrand disease and in patients with mild-to-moderate von Willebrand disease when desmopressin use is known or suspected to be inadequate. (formularywatch.com)
  • Desmopressin can also be administered via injection, either intramuscularly or subcutaneously. (rawoodfoundation.org)
  • There is limited information regarding Off-Label Guideline-Supported Use of Desmopressin (nasal) in adult patients. (wikidoc.org)
  • There is limited information regarding Off-Label Non-Guideline-Supported Use of Desmopressin (nasal) in adult patients. (wikidoc.org)
  • Precautions to consider when using desmopressin include closely monitoring fluid intake and output, as well as sodium levels, to prevent fluid imbalance. (mrmed.in)
  • Desmopressin was first approved by the U.S. Food and Drug Administration (FDA) for medical use on November 1, 1978. (mrmed.in)
  • This behavior is reminiscent of desmopressin, the most widely prescribed antidiuretic drug in the world. (bvsalud.org)
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  • The choice of the appropriate form of desmopressin depends on the patient's condition, the severity of the condition, the desired speed of onset, and individual preferences. (rawoodfoundation.org)
  • Infliximab injection comes as a powder to be mixed with sterile water and administered intravenously (into a vein) by a doctor or nurse. (oncology-drugs.net)
  • Desmopressin acetate will often maintain hemostasis in patients with hemophilia A during surgical procedures and postoperatively when administered 30 minutes prior to scheduled procedure. (druglib.com)
  • Desmopressin acetate will also stop bleeding in hemophilia A patients with episodes of spontaneous or trauma-induced injuries such as hemarthroses, intramuscular hematomas or mucosal bleeding. (druglib.com)
  • Desmopressin acetate will usually stop bleeding in mild to moderate von Willebrand's patients with episodes of spontaneous or trauma-induced injuries such as hemarthroses, intramuscular hematomas or mucosal bleeding. (druglib.com)
  • In addition, cranial surgical procedures, such as transsphenoidal hypophysectomy, create situations where an alternative route of administration is needed as in cases of nasal packing or recovery from surgery. (druglib.com)