• Method for preparing a steroidal carbothioic acid by reacting steroidal carboxylic acids or salts with carbodiimides alone or in conjunction with a coupling enhancer followed by reaction with a nucleophilic sulfur containing agent. (allindianpatents.com)
  • The present invention relates to a novel process for the conversion of steroidal carboxylic acids to carbothioate derivatives such as fluticasone propionate via novel intermediates. (allindianpatents.com)
  • Coupling agents and enhancers have primarily been used in peptide chemistry where the need to activate carboxylic acids in order to facilitate peptide couplings has been recognized for decades (Handbook of Reagents for Organic Synthesis, Activating Agents and Protecting Groups, ed. (allindianpatents.com)
  • Carboxylic acids. (lookformedical.com)
  • Carboxylic acids can be saturated, unsaturated, or aromatic. (lookformedical.com)
  • Novel oxazolidinone derivatives with a difluorophenyl moiety, represented by Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition containing the same as an active ingredient are provided. (justia.com)
  • The present invention relates to novel oxazolidinone derivatives with a difluorophenyl moiety, pharmaceutically acceptable salts thereof, a method for preparing the same, and an antibiotic composition containing the same as an active ingredient. (justia.com)
  • and a reaction layer containing at least pyrrolo-quinoline quinone dependent glucose dehydrogenase, formed in contact with or in the vicinity of the electrode system, and the reaction layer contains at least one kind of additive selected from the group consisting of gluconic acid and salts thereof. (patsnap.com)
  • New oxathiazin-like compounds and their derivatives are useful as antineoplastic and antimicrobial agents. (justia.com)
  • belongs to the class of organic compounds known as perfluorooctane sulfonic acid and derivatives. (t3db.ca)
  • These are organic compounds containing an octyl chain attached to the sulfur of a sulfonic acid (or a derivative thereof), where all hydrogens of the octyl chain are replaced by fluorine atoms. (t3db.ca)
  • The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. (patsnap.com)
  • This group of compounds includes amino acids and fatty acids. (lookformedical.com)
  • Amide group has a high chemical activity which can forms a series of derivatives with many kinds of compounds. (atamanchemicals.com)
  • Contains the nine amino acids that the body cannot produce and essential fatty acids. (hautecustombeauty.com)
  • Rich in Vitamin A, B and E for deep hydrating and soothing effects and its fatty acids help with a purified look. (hautecustombeauty.com)
  • Numerous skin benefits from its bioactive molecules including vitamin C, vitamin E, folate and restorative fatty acids with superior deep hydration properties. (hautecustombeauty.com)
  • Has restorative properties and a rich source of fatty acids for soothing benefits. (hautecustombeauty.com)
  • WO 2006/135881 describes quaternized ammonium salts prepared by condensation of a hydrocarbyl-substituted acylating agent and of an oxygen- or nitrogen-containing compound with a tertiary amino group, and subsequent quaternization by means of hydrocarbyl epoxide in the presence of stoichiometric amounts of an acid, especially acetic acid. (trea.com)
  • Except for a few solvent such as acetic acid, acrylic acid, ethylene glycol, glycerol and formamide, Anionic Polyacrylamide is generally insoluble in organic solvents. (atamanchemicals.com)
  • In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. (patsnap.com)
  • The reagent comprises dehydrogenase enzyme that has specificity for the analyte, NAD, an NAD derivative, pyrrolo-quinoline quinone (PQQ), or a PQQ derivative, a tetrazolium dye precursor, a diaphorase enzyme or an analog thereof, and a nitrite salt. (patsnap.com)
  • In general, the invention relates to a process for the preparation of acesulfame or a derivative thereof. (justia.com)
  • More specifically, the invention relates to a process, to a product obtainable by the process and the use of a specified velocity of flow for improving yield in the preparation of acesulfame or a derivative thereof. (justia.com)
  • The invention relates to a process for the preparation of a product, the product being 6-methyl-3,4-dihydro1,2,3-oxathiazin-4-one 2,2-dioxide or a derivative thereof, the process comprising the following steps: a. (justia.com)
  • The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. (gc.ca)
  • The problem to be solved by the present invention is to provide a new method for the preparation of steroidal carbothioic acid and derivatives thereof such as fluticasone propionate, especially a method in which a number of the relevant method steps may be performed as a continuous one-pot synthesis. (allindianpatents.com)
  • The present invention provides a method which comprises A) reacting a steroidal carboxylic acid or a salt thereof with a coupling agent alone or in conjunction with a coupling enhancer, and B) reacting the product of step A) with a nucleophilic agent comprising a sulfur atom. (allindianpatents.com)
  • Derivatives of ethylene, a simple organic gas of biological origin with many industrial and biological use. (lookformedical.com)
  • Disclosed is a process for preparing a pharmacologically active compound, in which at least one internal conjugation site of an Fc domain sequence is selected that is amenable to conjugation of an additional functional moiety by a defined conjugation chemistry through the side chain of an amino acid residue at the conjugation site. (patsnap.com)
  • An appropriate amino acid residue for conjugation may be present in a native Fc domain at the conjugation site or may be added by insertion (i.e., between amino acids in the native Fc domain) or by replacement (i.e., removing amino acids and substituting different amino acids). (patsnap.com)
  • A non-essential amino acid that is synthesized from GLUTAMIC ACID. (lookformedical.com)
  • An amino acid derived from silk that boosts skin appearance and supports the look of a replenished, lifted complexion. (hautecustombeauty.com)
  • Compound 12 displayed more potent DPPH radical scavenging activity than prenylated and (or) glucosided derivatives (2-4, or 10). (bvsalud.org)
  • 9~ yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R, 5S, cis)-4-amino-5- fluoro-l-(2~ hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, EmtrivaTM, (-)-cis FTC) and their physiologically functional derivatives. (gc.ca)
  • The intermediate (such as an ester of formula (III)) is very suitable for use in a method for the conversion of a steroidal carboxylic acid to a steroidal carbothioic acid or a carbothioate. (allindianpatents.com)
  • In the preparation of fluticasone propionate, the introduction of the CH2F-moiety has been accomplished by the reaction of the carbothioic metal salt with a dihalomethane derivative, preferably a fluorohalomethane. (allindianpatents.com)
  • These dyes and compositions are also useful as probes in nucleic acid and protein detection. (justia.com)
  • B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases. (patsnap.com)
  • Disclosed are a preparation method for a kinase inhibitor and a use thereof. (justia.com)
  • Methods: This review aims to cover the different polymer-based gel types, the development and characterization methods, as well as applications thereof. (eurekaselect.com)
  • Within the field of steroids the use of coupling agents have also found use, especially in the preparation of carbothioic acids and esters of the androstane series (e.g. (allindianpatents.com)
  • The activity and capacity of gallic acid (GA) and methyl gallate (MG) in scavenging DPPH· were determined in different solvents. (bvsalud.org)
  • Provided is a resist composition which generates an acid upon exposure to light and of which the solubility in a developing solution changes due to the action of an acid. (sumobrain.com)
  • Provided are, inter alia, an active-ray-sensitive or radiation-sensitive resin composition containing a resin that increases in polarity under the action of acid and a compound having a specified structure, an active-ray-sensitive or rad. (sumobrain.com)
  • This resist composition, which generates an acid by being exposed to light and of which the solubility in a developer changes due to the action of the acid, contains a resin component (A1) of which the solubility in a developer changes d. (sumobrain.com)
  • The reagent comprises dehydrogenase enzyme that has specificity for the analyte, NAD, an NAD derivative, pyrrolo-quinoline quinone (PQQ), or a PQQ derivative, a tetrazolium dye precursor, a diaphorase enzyme or an analog thereof, and a nitrite salt. (patsnap.com)