• Lambert, Tristan H. / Cross-coupling of sulfonic acid derivatives : Via aryl-radical transfer (ART) using TTMSS or photoredox . (psu.edu)
  • Nacsa, ED & Lambert, TH 2018, ' Cross-coupling of sulfonic acid derivatives: Via aryl-radical transfer (ART) using TTMSS or photoredox ', Organic Chemistry Frontiers , vol. 5, no. 1, pp. 64-69. (psu.edu)
  • We developed a novel synthetic method of a chiral cyclohexenyl amine derivative having an aryl group at the 2-posotion by palladium catalyst for the synthesis of (-)-mesembrine. (heterocycles.jp)
  • Aryl sulfonic acids are produced by the process of sulfonation . (wikizero.com)
  • Many sulfonic acids are prepared by hydrolysis of sulfonyl halides and related precursors. (wikizero.com)
  • Thus, perfluorooctanesulfonic acid is prepared by hydrolysis of the sulfonyl fluoride, which in turn is generated by the electrofluorination of octanesulfonic acid. (wikizero.com)
  • Similarly the sulfonyl chloride derived from polyethylene is hydrolyzed to the sulfonic acid. (wikizero.com)
  • In general, the invention relates to a process for the preparation of acesulfame or a derivative thereof. (justia.com)
  • More specifically, the invention relates to a process, to a product obtainable by the process and the use of a specified velocity of flow for improving yield in the preparation of acesulfame or a derivative thereof. (justia.com)
  • The invention relates to a process for the preparation of a product, the product being 6-methyl-3,4-dihydro1,2,3-oxathiazin-4-one 2,2-dioxide or a derivative thereof, the process comprising the following steps: a. (justia.com)
  • These are organic compounds containing an octyl chain attached to the sulfur of a sulfonic acid (or a derivative thereof), where all hydrogens of the octyl chain are replaced by fluorine atoms. (t3db.ca)
  • In this regard, the present study reports the green synthesis of new benzaldazine and ketazine derivatives via the condensation of various carbonyl compounds (aldehydes and ketones with the 3-(1-hydrazineylideneethyl)-1H-indole using the grinding method with one drop of acetic acid). (dntb.gov.ua)
  • For example, p -Toluenesulfonic acid and methanesulfonic acid have p K a values of −2.8 and −1.9, respectively, while those of benzoic acid and acetic acid are 4.20 and 4.76, respectively. (wikizero.com)
  • WO 2006/135881 describes quaternized ammonium salts prepared by condensation of a hydrocarbyl-substituted acylating agent and of an oxygen- or nitrogen-containing compound with a tertiary amino group, and subsequent quaternization by means of hydrocarbyl epoxide in the presence of stoichiometric amounts of an acid, especially acetic acid. (trea.com)
  • [a] Salts or esters of sulfonic acids are called sulfonates . (wikizero.com)
  • This strategy demonstrated five component reactions of two equivalents of aldehydes, two equivalents of anilines and (3-keto esters in ethanol using 10 mol% of camphor sulfonic acid at reflux. (lupinepublishers.com)
  • The chiral cyclohexenyl amine derivative having the sylyloxymethyl group at the 2-position was synthesized using the palladium catalyst. (heterocycles.jp)
  • The progress of the synthesis of a chiral cyclohexenyl amine derivative having the substituent at the 2-position was described. (heterocycles.jp)
  • A sulfonic acid can be thought of as sulfuric acid with one hydroxyl group replaced by an organic substituent . (wikizero.com)
  • They are also usually colourless and nonoxidizing, [6] which makes them suitable for use as acid catalysts in organic reactions. (wikizero.com)
  • Also, camphor sulfonic acid (CSA) is achieving enormous significance in organic synthesis, as this catalyst is used in the synthesis of chromans, ligands, and pseudo glycosides, as an auxiliary and in some polymerization reactions [8]. (lupinepublishers.com)
  • belongs to the class of organic compounds known as perfluorooctane sulfonic acid and derivatives. (t3db.ca)
  • Methods for the preparation of a lipid-nucleic acid composition are provided. (justia.com)
  • According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino lipid and a lipid such as a PEG- or Polyamide oligomer-modified lipid is combined with a buffered aqueous solution of a charged therapeutic agent, for example polyanionic nucleic acids, to produce particles in which the therapeutic agent is encapsulated in a lipid vesicle. (justia.com)
  • This invention relates to compositions comprising a combination of a lipid and a therapeutic agent, particularly to lipid-nucleic acid compositions, for in vivo therapeutic use. (justia.com)
  • Additionally, the invention provides methods of making the compositions, as well as methods of introducing the nucleic acids into cells using the compositions and treating disease conditions. (justia.com)
  • No clinical assessment currently employs the basic phosphodiester chemistry found in natural nucleic acids, because of these and other known problems. (justia.com)
  • These dyes and compositions are also useful as probes in nucleic acid and protein detection. (justia.com)
  • Furthermore, the anticancer activities of the reported azine derivatives were evaluated against colon, hepatocellular, and breast carcinoma cell lines using the MTT technique with doxorubicin as a reference medication. (dntb.gov.ua)
  • These results along with the structure-activity relationship (SAR) of the reported derivatives will pave the way for the design of additional azines bearing indole with potential anticancer activities. (dntb.gov.ua)
  • Koeberg‐Telder A, Cerfontain H . Acid-catalyzed transfer sulfonation of anisole using overcrowded polymethylbenzenesulfonic acids†‡ Recueil Des Travaux Chimiques Des Pays-Bas . (academictree.org)
  • Ansink HRW, Cerfontain H . Sulfonation of 1, 2‐(methylenedioxy)benzene, 1, 2‐(ethylenedioxy)benzene, 2‐methylanisole, 2, 3‐dihydrobenzofuran, chromane, benzo‐15‐crown‐5 and dibenzo‐30‐crown‐10 in concentrated sulfuric acid and with sulfur trioxide Recueil Des Travaux Chimiques Des Pays-Bas . (academictree.org)
  • Cerfontain H , Koeberg-Telder A. Sulfonation and sulfation on reaction of 1,4‐dihydroxybenzene and its methyl ethers in concentrated sulfuric acid Recueil Des Travaux Chimiques Des Pays-Bas . (academictree.org)
  • Combined with the trivial preparation of the substrates from activated sulfonic acids and 2-halophenols or anilines, this work presents a useful means to employ sulfonic acid derivatives in cross-coupling transformations. (psu.edu)
  • The intramolecular cross-coupling of sulfonic acid derivatives occurs in the presence of tris(trimethylsilyl)silane (TTMSS) at room temperature and in air to form biaryl compounds. (psu.edu)
  • New oxathiazin-like compounds and their derivatives are useful as antineoplastic and antimicrobial agents. (justia.com)
  • Perfluorooctanesulfonic acid or perfluorooctane sulfonate (PFOS), is a man-made fluorosurfactant and global pollutant. (t3db.ca)
  • The development of new approaches for the synthesis of new bioactive heterocyclic derivatives is of the utmost importance for pharmaceutical industry. (dntb.gov.ua)
  • A simple and efficient protocol has been developed for the synthesis of highly substituted Piperidines derivatives. (lupinepublishers.com)
  • So far, to the best of our knowledge, there is no report available on the use of camphor sulfonic acid as an organ catalyst for the synthesis of highly substituted Piperidines. (lupinepublishers.com)
  • [4] Sulfonic acids are known to react with solid sodium chloride ( salt ) to form the sodium sulfonate and hydrogen chloride. (wikizero.com)
  • The molecular interactions between derivatives 3a-h, 7, 9, 11, 13, and the CDK-5 enzyme (PDB ID: 3IG7) were studied further using molecular docking indicating a high level of support for the experimental results. (dntb.gov.ua)
  • The overall geometry of the sulfur centre is reminiscent of the shape of sulfuric acid . (wikizero.com)
  • Various spectroscopic techniques were used to identify the structures of the synthesized derivatives. (dntb.gov.ua)
  • Hydrogen bonding significantly influences the properties of primary and secondary amines as well as the protonated derivatives of all amines. (newworldencyclopedia.org)
  • Their polarity, in conjunction with their high acidity, renders short-chain sulfonic acids water-soluble, while longer-chain ones exhibit detergent-like properties. (wikizero.com)
  • A comparative study was established between the present derivative (I-6) and their previously prepared isomer. (dntb.gov.ua)
  • The sulfonic acid group, RSO 2 OH features a tetrahedral sulfur centre, meaning that sulfur is at the center of four atoms: three oxygens and one carbon. (wikizero.com)
  • Recently, our group synthesized 1,5-benzodiazepine, α-hydroxy and α-amino phosphonates using camphor sulfonic acid as organ catalyst [7]. (lupinepublishers.com)
  • For instance, various sources have reported the p K a of methanesulfonic acid to be as high as −0.6 [3] or as low as −6.5. (wikizero.com)
  • Because of their polarity, sulfonic acids tend to be crystalline solids or viscous, high-boiling liquids. (wikizero.com)
  • DSC and POM investigations revealed that all the synthesized derivatives are purely nematogenic exhibiting only nematic (N) mesophase, except for the longest chain derivative (I-12) that is dimorphic possesses smectic A and N phases. (dntb.gov.ua)
  • Alkylsulfonic acids can be prepared by many methods. (wikizero.com)
  • They are commonly cited as being around a million times stronger than the corresponding carboxylic acid. (wikizero.com)