• The most widely used fluoresceins include fluorescein isothiocyanate (FITC) for labeling proteins (in particular antibodies) and carboxyfluoresceins (5-FAM and 5(6)-FAM ) for labeling peptides and oligonucleotides. (aatbio.com)
  • TAMRA is one of the few fluorescent dye molecules that can be used to label proteins, so it is widely used as the marker of peptides and proteins. (bocsci.com)
  • 5-TAMRA is widely used to prepare biological fluorescent groups, including peptides, proteins, nucleic acids, nucleotides, fluorescent antibodies, especially antibody fluorescent groups and avidin derivatives in immunohistochemistry. (bocsci.com)
  • 6-TAMRA is mainly used for automatic DNA sequencing and can react with primary or secondary amine groups in proteins, nucleic acids and other biomolecules. (bocsci.com)
  • FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. (axispharm.com)
  • Peptides are chains of proteins responsible for metabolic processes in our body, as well as for. (npcriz.co)
  • These projects involve mostly the chemistry of nucleotides and nucleic acids, the synthesis of peptides and b-lactame derivatives and the methodological developments for post-functionalization of biomolecules. (gp2a.org)
  • Synthesis of the DOTA-PNA conjugates was followed by automated elongation with a peptide sequence (PTD-4-glycine, PTD-4-G), known to mediate cellular internalization of impermeable effector molecules, or its retro-inverso analogue (ri-PTD-4-G). Preparation of the four conjugates required an innovative synthetic strategy, using mild acid conditions to generate hydrophobic, partially deprotected intermediates. (nih.gov)
  • Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics. (univ-rennes.fr)
  • Synthesis of Some Cyclic Methylene 1,3-Diaza Barbiturates Derivatives. (mpg.de)
  • Facile synthesis of peptide nucleic acids and peptide nucleic acid-peptide conjugates on an automated peptide synthesizer. (mpg.de)
  • MR contrast agent composed of cholesterol and peptide nucleic acids: Design, synthesis and cellular uptake. (mpg.de)
  • Peptides represent over decades of innovative peptide synthesis expertise. (anaspec.com)
  • AnaSpec offers 320 reagents for peptide synthesis. (anaspec.com)
  • She co-organized « the XXII Roundtable on Nucleosides, Nucleotides and Nucleic Acids », at the Pasteur Institut, (Paris, july 2016). (gp2a.org)
  • We offer a broad selection of fluorescein products including reactive fluorescein and fluorescein derivatives for labeling antibodies, nucleic acids and other biomolecules, conjugates, indicators, and substrates for detecting enzymatic activity in cells, homogenates and solution. (aatbio.com)
  • TAMRA, carboxyl tetramethy lrhodamine, is a luciferin derivative of rhodamine, which is widely used in the preparation of biological conjugated fluorophore, especially for fluorescent antibodies and avidin derivatives used in immunochemistry. (bocsci.com)
  • Four peptide-PNA constructs were synthesized by a combination of manual and automated stepwise elongation techniques, including bcl-2 antisense conjugates and nonsense conjugates with no complementarity to any known mammalian gene or DNA sequence. (nih.gov)
  • These intermediates were purified by semipreparative reversed-phase HPLC and completely deprotected to yield pure peptide-PNA conjugates in 6% to 9% overall yield. (nih.gov)
  • Pyrene-PEG-COOH, with a pyrene and a carboxyl group at each end of the molecular chain, is a fluorescent heterofunctional PEG derivative. (bocsci.com)
  • Fluorescein derivatives are one of the most commonly used fluorescent labels for biological detection in flow cytometry and immunofluorescence due to their high absorptivity, excellent fluorescence quantum yields and good water solubility. (aatbio.com)
  • Using modifications of this synthetic strategy, the ri-PTD-4-G conjugate of bcl-2 antisense PNA was prepared using a lysine derivative of tetramethylrhodamine (TMR) for fluorescence microscopy. (nih.gov)
  • Synthetic peptide nucleic acid oligomers have been used in recent years in molecular biology procedures, diagnostic assays, and antisense therapies. (wikipedia.org)
  • With over 25 years of peptide manufacturing experience, AnaSpec is your trusted source of highly complex peptides. (anaspec.com)
  • AnaSpec manufactures many categories of peptides in Fremont, California, USA. (anaspec.com)
  • Biofilm prevention, inhibition and controlling process (antibiofilm) using natural or synthetic peptides derived from 2S-sulfur-rich seed storage protein 2-like protein or their peptidomimetic (synthetic) derivatives. (univ-rennes.fr)
  • 2019 Peptides NPCRIZ: Effective Protection of the Liver and Pancreas The human body works as a single, well-coordinated mechanism and any failure in the work of. (npcriz.co)
  • The objective of this work was to synthesize an antisense peptide nucleic acid (PNA) complementary to the first six codons of the bcl-2 open reading frame, conjugated to a membrane-permeating peptide for intracellular delivery, and modified with a bifunctional chelating agent for targeting imaging and therapeutic radiometals to tumors overexpressing bcl-2. (nih.gov)
  • Comparison of a lipid- vs. peptide-based delivery system for intracellular targeted MR imaging probes. (mpg.de)
  • Either stereo reactants or stereo catalysis from achiral or chiral molecules are a prerequisite to obtain pure enantiomeric lipid derivatives. (mdpi.com)
  • The various purine and pyrimidine bases are linked to the backbone by a methylene bridge (-CH 2-) and a carbonyl group (-(C=O)-). PNAs are depicted like peptides, with the N-terminus at the first (left) position and the C-terminus at the last (right) position. (wikipedia.org)
  • Though an unmodified PNA cannot readily cross the cell membrane to enter the cytosol, covalent coupling of a cell penetrating peptide to a PNA can improve cytosolic delivery. (wikipedia.org)
  • Role of exofacial protein thiols in the cytosolic delivery of the cysteine-rich cell penetrating peptide CyLoP-1. (mpg.de)
  • 2017 Peptides in bodybuilding Hormones take a leading position among drugs to increase muscle mass, burn fat and increase stamina. (npcriz.co)
  • PEG linkers between pyrene and carboxylic acid groups offer better water solubility, fewer steric hindrances and higher stability. (bocsci.com)
  • Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. (bocsci.com)
  • Scanning confocal fluorescence microscopy of TMR-labeled ri-PTD-4-G-anti-bcl-2 PNA in Raji lymphoma cells demonstrated that the retro-inverso peptide was active in membrane permeation and mediated cellular internalization of the antisense PNA into the cytoplasm, where high concentrations of bcl-2 mRNA are expected to be present. (nih.gov)
  • Modulation of tight junctions by peptides to increase drug penetration across biological barriers. (u-szeged.hu)
  • Seven gelatin authentication methods that have been developed include: nucleic acid based, immunochemical, electrophoretic analysis, spectroscopic, mass-spectrometric, chromatographic-chemometric and chemisorption methods. (halalnews.info)
  • BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. (bocsci.com)
  • 2018 Which peptides are the most important President of the Gerontological Society at the Russian Academy of Sciences, Doctor of Medical. (npcriz.co)
  • Pseudonajide is a short peptide antibiotic derived from snake venom that acts at low concentration interfering with cell wall and inhibiting biofilm. (univ-rennes.fr)
  • 2017 The difference between peptides like GHRP-2 and GHRP-6 from Chavinson peptides All bodybuilders must read this article!Ghrp peptides A few years ago the world of bodybuilding was. (npcriz.co)
  • described a trans-acting DNA-based amphiphatic delivery system for convenient delivery of poly A tailed uncharged nucleic acids (UNA) such as PNAs and morpholinos, so that several UNA's can be easily screened ex vivo. (wikipedia.org)
  • The approaches include use of the amino acid profile, the presence of specific peptide and DNA markers and the spectral fingerprint of gelatins or its peptides. (halalnews.info)
  • Plasma stability studies showed that (111)In-DOTA-labeled ri-PTD-4-G-anti-bcl-2 PNA was stable for 168 h at 37 degrees C, unlike the conjugate containing the parent peptide sequence. (nih.gov)
  • Evaluation of the oncopharmacological potentials of the novel A-ring modified 13α-estrone derivatives. (u-szeged.hu)
  • As a research organization that provides full-service PNA services, Creative Peptides ' customer-centric collaborative approach helps us build true partnerships with customers. (creative-peptides.com)
  • 2018 Previn and Peptide complex 19 - a complex for the prevention of cardiovascular diseases September 29 all over the world, at the initiative of the World Heart Federation, with the support. (npcriz.co)
  • Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation. (univ-rennes.fr)
  • Improvement of the solubility and dissolution rate of nifluminic acid to achieve rapid drug release. (u-szeged.hu)
  • 2018 Antitumor effect of peptides The modern period of development of medicine is characterized by significant achievements in the. (npcriz.co)
  • In: Peptides 2008: Chemistry of Peptides in Life Science Technology and Medicine, 4-19-122, pp. 550 - 551 (Eds. (mpg.de)