• A Rational Design of Catechol-Based Compounds: An Experimental and Theoretical Study of Optical Properties. (univ-grenoble-alpes.fr)
  • The antioxidant activities of all isolated compounds were examined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. (bvsalud.org)
  • The antioxidant properties of these compounds were determined by their rates of reaction with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and their oxidation potentials from cyclic voltammetry. (bvsalud.org)
  • Heterocyclic compounds derived from catechol ethers. (royalsoc.org.au)
  • Isomer-dependent catalytic pyrolysis mechanism of the lignin model compounds catechol, resorcinol and hydroquinone. (psi.ch)
  • In the convergent mode, structurally diverse aromatic compounds are converted to one of a few aromatic ring cleavage substrates such as catechol, gent sate, protocatechuate and their derivatives [ 5 ]. (biomedcentral.com)
  • Orto - and para -dihydroxybenzene (DHB) compounds, such as catechol (CAT) and hydroquinone (HQ), have capacity to reduce iron(III) 9 9 Chen, R. (scielo.br)
  • It belongs to the family of compounds known as catecholamines and derivatives. (hmdb.ca)
  • These are compounds containing 4-(2-aminoethyl) pyrocatechol [4-(2-aminoethyl) benzene-1,2-diol] or a derivative thereof. (hmdb.ca)
  • Belongs to the class of organic compounds known as catechols. (hmdb.ca)
  • Catechols are compounds containing a 1,2-benzenediol moiety. (hmdb.ca)
  • Any compound having a catechol structure, like catecholestrogens and catechol-containing flavonoids, are substrates of COMT. (en-academic.com)
  • p-Xylene-grown cells contained an inducible NAD+-dependent dehydrogenase which formed catechols from cis-p-toluate diol and the analogous acid diols formed from the other hydrocarbon substrates listed above. (rhea-db.org)
  • Oxygenases belong to the oxidoreductive group of enzymes (E.C. Class 1), which oxidize the substrates by transferring oxygen from molecular oxygen (O 2 ) and utilize FAD/NADH/NADPH as the co-substrate. (biomedcentral.com)
  • Substrates containing a -COOH group are inhibitors for catechol oxidase. (lookformedical.com)
  • A comparison of Langmuirian binding constants for alizarin red S (1.4 x 10(5) mol(-1) dm(3)), catechol (8.4 x 10(4) mol(-1) dm(3)), caffeic acid (7.5 x 10(4) mol(-1) dm(3)), dopamine (1.0 x 10(4) mol(-1) dm(3)), and L-dopa (8 x 10(3) mol(-1) dm(3)) reveals that a combination of hydrophobicity and electrostatic interaction causes considerable selectivity effects. (bath.ac.uk)
  • Substrate specificity of catechol oxidase from Lycopus europaeus and characterization of the bioproducts of enzymic caffeic acid oxidation. (lookformedical.com)
  • It is the N-acetylated derivative of dopamine. (wikipedia.org)
  • However, the mechanisms involved in SUD are far more complex and rely also on structural changes of the prefrontal cortex (PFC) with reduction of the activity of this region, through a mechanism of downregulation of dopamine receptors type 2 (DRD2), in the striatum, resulting in impaired self-control and impulsive behaviours [ 6 ]. (biomedcentral.com)
  • 2 Levodopa enters dopaminergic neurons where it is metabolised to dopamine, replacing the depleted endogenous neurotransmitter. (bmj.com)
  • Both of these subclasses target dopamine D 2 -type receptors. (bmj.com)
  • Apomorphine, one of the first dopamine agonists shown to improve parkinsonian symptoms, is a combined D 1 and D 2 agonist but has to be administered subcutaneously. (bmj.com)
  • Catechol- O -methyltransferase is involved in the inactivation of the catecholamine neurotransmitters ( dopamine , epinephrine , and norepinephrine ). (en-academic.com)
  • It is an endogenously produced derivative or metabolite of dopamine. (hmdb.ca)
  • The contribution of irradiation and the dihydroxybenzenes (DHB), catechol (CAT) and hydroquinone (HQ), added or formed as phenol oxidation intermediates, was evaluated for the reduction of Fe III and for phenol degradation via Fenton processes. (scielo.br)
  • Hydroquinone is an aromatic organic compound that is a type of phenol, and a derivative of benzene. (camlinfs.com)
  • In humans, catechol- O -methyltransferase protein is encoded by the COMT gene . (en-academic.com)
  • [ 2 ] As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. (en-academic.com)
  • A new synthesis of the catechol-𝑂-methyltransferase (COMT) inhibitor, entacapone (E-isomer) has been achieved under mild conditions by amine-mediated demethylation of the precursor 2-Cyano-3-(3-hydroxy-4-methoxy-5-nitrophenyl) prop-2-eneamide, wherein the methoxyl group adjacent to a nitro group gets demethylated under nucleophilic attack. (ias.ac.in)
  • 2) N-dealkylation, deamination and only for MDA, MDMA, MDE oxidation to the corresponding benzoic acid derivatives conjugated with glycine. (erowid.org)
  • Pt( II ) catecholates containing 2,2′-bipyridine-4,4′-di-carboxylic acid (dcbpy) have been prepared from their parent iso-propyl ester derivatives, complexes of 2,2′-bipyridine-4,4′-di-C(O)O i Pr, (COO i Pr) 2 bpy, and their photophysical and electrochemical properties studied. (rsc.org)
  • Modifying diimine Pt( II ) catecholates with carboxylic acid functionality has allowed for the anchoring of these complexes to thin film TiO 2 , where steric bulk of the complexes (3,5-di t Bu-catechol vs. catechol) has been found to significantly influence the extent of monolayer surface coverage. (rsc.org)
  • The N-hexadecyl-pyridinium-4-boronic acid hexafluorophosphate monolayer acts as an active receptor for 1,2-dihydroxy-benzene (catechol) derivatives in aqueous media. (bath.ac.uk)
  • It is shown that the immobilised boronic acid monolayer acts as sensor film for a wider range of catechols. (bath.ac.uk)
  • Treatment of P. putida BG1 with nitrosoguanidine led to the isolation of a mutant strain which, when grown with fructose, oxidized both p-xylene and p-toluate to (-)-cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylic acid (cis-p-toluate diol). (rhea-db.org)
  • The structure of the diol was determined by conventional chemical techniques including identification of the products formed by acid-catalyzed dehydration and characterization of a methyl ester derivative. (rhea-db.org)
  • Structure-dependent antiviral activity of catechol derivatives in pyroligneous acid against the encephalomycarditis virus. (researchmap.jp)
  • Exogenous application of SA and some other chemicals including: polyacrylic acid, acetyl salicylic acid, 2, 6-dichloroisonicotinic acid, methyl salicylate, jasmonic acid and jasmonic methyl ester, benzothiadiazole derivatives, DL-B-aminobutyric acid and oxalic acid, can induce accumulation of pathogenensis-related proteins and lead to reduced incidence of several diseases on many crops (Gozzo, 2003). (scialert.net)
  • The principal routes of metabolism are methylation of the catechol and conjugation. (drugs.com)
  • N-Acetyldopamine is the organic compound with the formula CH3C(O)NHCH2CH2C6H3(OH)2. (wikipedia.org)
  • Catechol is a natural compound found in various fruits and vegetables. (dpsnutrition.net)
  • Compound 12 displayed more potent DPPH radical scavenging activity than prenylated and (or) glucosided derivatives (2-4, or 10). (bvsalud.org)
  • If the catechol substrate is not symmetric and its cleavage site preference is unknown, the compound is cleaved on both sides of the vic -dihydroxyl group. (ethz.ch)
  • 4-Tert-butyIcatechoI is an organic chemical compound obtained by the butylation of Catechol using Isobutene gas. (camlinfs.com)
  • The highest stoichiometries for GA vs. MG were in 2-PrOH (6.67 vs. 5.37), followed by EtOH (5.84 vs. 4.57), MeOH (5.34 vs. 3.8) ~ acetone (5.02 vs. 4.44), MeCN (3.68 vs. 3.05) ~ t-BuOH (3.14 vs. 2.99), THF (2.34 vs. 2.2), ethyl acetate (1.2 vs. 0.93), and 1,4-dioxane (0.34 vs. 0.35). (bvsalud.org)
  • Similar demethylation was achieved on ethyl 2-cyano-3-(3,4-dimethoxy-5-nitrophenyl) prop-2-enoate, 2-cyano-3-(3,4-dimethoxy-5-nitrophenyl)-N,N-diethylprop-2-enamide, ethyl 2-cyano-3-(3-hydroxy-4-methoxy-5-nitrophenyl) prop-2-enoate and ethyl 2-cyano-3-(4-methoxy-3-nitrophenyl) prop-2-enoate. (ias.ac.in)
  • Analogues of ethyl 2-cyano-3-(3,4-dimethoxy-5-nitrophenyl) prop-2-enoate wherein a methoxyl group is not adjacent to a NO 2 group are unaffected and phenolic derivatives yield the amine salts. (ias.ac.in)
  • Compared with other published methods, condensation with a preexisting cyclohexane moiety in the precursor is needed to gain the heterogenic tricycle systems, whereas we present a novel strategy towards cannabinoid derivatives based on a flexible modular synthesis. (beilstein-journals.org)
  • The 3-O-methyl derivative of dobutamine is inactive. (drugs.com)
  • On the threshold photoelectron spectrum of fulvenone, a reactive ketene derivative in lignin valorization. (psi.ch)
  • The concentrations of lignin derivatives (specifically humic substances) were hypothesized to have direct influences on sulfide color reversion. (auburn.edu)
  • [8] . Another example, indicating the importance of the well-known [4 + 2] cycloaddition in natural-product synthesis, is the first published total synthesis of Taxol ( 2 ) by Nicolaou. (beilstein-journals.org)
  • One study showed in increase in NGF of 140% over controls (2), multiple other studies have confirmed the de novo NGF synthesis capability of 4-MC while also demonstrating its ability to significantly increase myelination and nerve blood flow (3-6). (dpsnutrition.net)
  • The synthesis of 2-aminomethyl-benziminazole and related substances. (royalsoc.org.au)
  • Synthesis of 1:2-dimethoxyacridine. (royalsoc.org.au)
  • We also investigated whether other chemically distinct siderophores (yersiniabactin and aerobactin) or the monomeric catechol 2,3-dihydroxybenzoate could provide protection against oxidative stress and found that only catecholate siderophores have this property. (nih.gov)
  • Segmented catalytic co-pyrolysis of biomass and high-density polyethylene for aromatics production with MgCl 2 , and HZSM-5. (psi.ch)
  • The Diels-Alder reaction is one of the most important processes for carbon-carbon-bond formation in organic chemistry [1,2] . (beilstein-journals.org)
  • The rate and degree of color reversion has been hypothesized to be related to four main mechanisms: 1) anaerobic color reduction, 2) anaerobic color generation via sulfide reaction, 3) aerobic color reversion, and 4) aerobic decolorization. (auburn.edu)
  • An enzyme of the oxidoreductase class that catalyzes the reaction between catechol and oxygen to yield benzoquinone and water. (lookformedical.com)
  • The plasma half-life of dobutamine in humans is 2 minutes. (drugs.com)
  • The catechol substituent is susceptible to redox and crosslinking. (wikipedia.org)
  • The free amino group of the corresponding oxazaborolidinone 33 was easily protected as a benzyl carbamate and then deprotected rapidly by treatment with 2-aminoethanol under microwave irradiation to furnish mono-protected 34 . (organic-chemistry.org)
  • The use of MOF as stationary phase in high resolution GC separation of aromatic hydrocarbons has also gained significant attention 2 . (ukessays.com)
  • It includes extradiol ring cleavage of vic -dihydroxybenzenoids ( bt0008 ) and distal ring cleavage of 1-amino-2-hydroxybenzenoids ( bt0041 ) to form 2-hydroxymuconate semialdehyde and 2-aminomuconate semialdehyde derivatives, respectively. (ethz.ch)
  • 3-Carboxyl catechols, such as 2,3-dihydroxy- p -cumate , undergo decarboxylation of the 3-carboxy group following meta cleavage. (ethz.ch)
  • Other important advantages are the relatively low cost of the reagents involved, the mild operation conditions employed, absence of iron toxicity and the environmentally benign character of H 2 O 2 at the concentrations used. (scielo.br)
  • Hydrolysis of the C5-C6 bond ( bt0040 ), or oxidation of the aldehyde to a carboxylate (bt0003), followed by decarboxylation (bt0051), produces a 2-amino-2,4-dienoate derivative or an enol product, which quickly tautomerizes to a 2-oxopent-4-enoate derivative. (ethz.ch)
  • The cis-relative stereochemistry of the hydroxyl groups was determined by the isolation and characterization of an isopropylidene derivative. (rhea-db.org)
  • 1,2,3,4-TCDD has been prepared by refluxing a mixture of catechol, potassium carbonate, pentachloronitro benzene and acetone in nitrogen (IARC 1977). (cdc.gov)
  • Water for Injection, USP is chemically designated H 2 O. (drugs.com)
  • 10.1002/ejoc.201300064 ) a procedure for the selective acetolysis of the perbenzylated sugar 1 to furnish 3 using isopropenyl acetate ( 2 ) instead of the more typical and high-boiling acetic anhydride. (organic-chemistry.org)
  • In the alveoli, agonism of beta-2 adrenergic receptors, activates similar pathways to the heart, however the end result is regulation of sodium channels, the cystic fibrosis transmembrane conductance regulator (CFTR), and sodium potassium ATPase. (drugbank.com)
  • In the first method, 2-bromo-4-chlorophenol and potassium hydroxide are dissolved in methanol and evaporated to dryness. (cdc.gov)
  • DCDD can also be synthesized by heating the potassium salt of 2,4-dichlorophenol in the presence of copper powder in a vacuum sublimation apparatus (IARC 1977). (cdc.gov)
  • 1,2,4,6,7,9-HxCDD has been made by heating the potassium salt of 2,3,5,6-tetrachlorophenol with powdered copper and potassium carbonate in a vacuum sublimation apparatus (IARC 1977). (cdc.gov)
  • 2-Aminomuconate semialdehyde derivatives undergoes hydrolytic deamination (bt0032) to form the 2-hydroxymuconate semialdehyde product. (ethz.ch)
  • condensation of a polychlorophenol and direct halogenation of the parent dibenzo- p -dioxin or a monochloro-derivative. (cdc.gov)
  • A dicyanamide bridged 2D polynuclear complex of copper(II) having molecular formula [Cu-2(L) (mu(1,5)-dca)(2)](n) (1) has been synthesized using the Schiff base ligand N,N'-bis(salicylidene)-1,3-diaminopentane, (H2L) and sodium dicyanamide (dca). (sdu.edu.tr)
  • Pore size can be a key in adsorption on MOFs due to micropore filling mechanism 2 , which suggests adsorption capacity depends on molecular cross-sectional area rather than minimum diameter. (ukessays.com)
  • 4-methylcatechol is a specific, bioavailable and well-researched form of catechol that provides some potent physiological effects. (dpsnutrition.net)